Paul M. Brennan - Publications, H-index & Citations

Paul M. Brennan

University of Edinburgh

58H指数

470论文数

2.1W被引数

收录论文 116

发表时间

Sequential Design of Activatable Photosensitizers for Ablation of Glioma Cells in Brain Cancer Tissues 用于脑癌组织中胶质瘤细胞消融的可激活光敏剂的顺序设计

Angewandte Chemie-International Edition

IF16.9

2026-10-01

OAAI

Utsa Karmakar; Zhiming Cheng; Andrew D. M. Green; Sam Benson; Eleni Nestoros; Clarissa Lim; Justyna Cholewa-Waclaw; Fabio de Moliner; Paula Lusarreta; Deborah Seah; Alsadeg Bilal; Neza Alfazema; Thibaud Aymoz-Bressot; Gillian Morrison; Sonja Vermeren; Steven M. Pollard; Paul M. Brennan; Michael G. Tanner; Marc Vendrell

Does earlier diagnosis and treatment of brain tumours matter? Time-to-treatment intervals and tumour size at detection; impact on survival and other patient outcomes 脑肿瘤的早期诊断和治疗是否重要？治疗时间间隔和检测时肿瘤大小对生存率及其他患者结局的影响

Neuro-Oncology Advances

IF4.1

2026-09-28

OAAI

Ewan Gray; James Cameron; Abigail Lishman; Peter Hall; Piyumanga Karunaratne; Giovanni Tramonti; Maheva Vallet; Luke Pike; Matthew Baker; Paul M Brennan

Development of a novel analytical pipeline to characterize morphological and molecular features of blood vessels within marginal regions of glioblastoma 开发一种新型分析流程以表征胶质母细胞瘤边缘区域血管的形态学和分子学特征

Neuro-Oncology Advances

IF4.1

2026-07-30

OAAI

Anubrata Das; Antoine Vallatos; Joanna Birch; Christopher Ireson; Gerry Thompson; Karen Strathdee; Karin Williams; Christine Littler; Helen Bulbeck; Paul Brennan; Val G Brunton; Colin Smith; Anthony J Chalmers

Multimodal survival analysis of glioblastoma using whole-slide histopathology, gene expression, clinical variables and language-model-derived mutation features 基于全切片组织病理学、基因表达、临床变量及语言模型衍生突变特征的多模态胶质母细胞瘤生存分析

Scientific Reports

IF3.9

2026-04-21

OAAI

Tongjie Wang; Javier Alfaro; Paul M. Brennan; Ajitha Rajan

Synthetic super-enhancers enable precision viral immunotherapy 合成超级增强子实现了精准病毒免疫疗法

Nature

IF48.5

2026-04-08

OAAI

Ute Koeber; Mantas Matjusaitis; Neza Alfazema; Katharine Furlong; Zeyu Wang; Rachel White; Alhafidz Hamdan; Pooran Dewari; Gregoire Morisse; Mariela Navarette; Rosie Willis; Jin Wang; Michelle P. Clark; Carla Jacinto de Sousa; Hei Ip Hong; Shahida Sheraz; Ben Southgate; Justyna Cholewa-Waclaw; Sabine Gogolok; Gillian M. Morrison; Felipe Galvez Cancino; Faye Robertson; Anna Williams; Susan J. Rosser; Paul M. Brennan; Dirk Sieger; Abdenour Soufi; Sergio A. Quezada; Steven M. Pollard

Comparison of GCS and GCS-P: A Systematic Review and Meta-analysis GCS和GCS-P的比较：一项系统评价和Meta分析

Neurosurgery

IF3.9

2026-04-01

PREAI

Aldamouni, Maeen; Sivam, Hariss; Brennan, Paul

A multi-centre performance evaluation of a commercially developed liquid biopsy for the earlier detection of brain tumours 多中心性能评估：一种商业化开发的液体活检技术在脑肿瘤早期检测中的应用

ESMO Open

IF8.3

2025-12-29

OAAI

P.M. Brennan; J.M. Cameron; D. Eustace; H.J. Butler; A. Sala; A. Lazarus; G. Antoniou; D.S. Palmer; E. Gray; C. Kerrie; S. McDonald; P. Black; S. Sheraz; I. Adekoya; A. Jakola; A. Denes; M.D. Jenkinson; J. Jones; S. Pendered; S. Koljenovic

Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma 单细胞蛋白质组学分析确定了人类胶质母细胞瘤中离散的中性粒细胞功能状态

Nature Communications

IF15.7

2025-12-15

OAAI

Pranvera Sadiku; Alejandro J. Brenes; Rupert L. Mayer; Leila Reyes; Patricia Coelho; Gabi van Stralen; Ailiang Zhang; Manuel A. Sanchez-Garcia; Emily R. Watts; Imran Liaquat; Andrew J. M. Howden; Ikeoluwa Adekoya; Anuka Boldbaatar; Allan MacRaild; Sarah Risbridger; Gillian M. Morrison; Heather MacPherson; Caroline M. Bruce; Shonna Johnston; Robert Grecian; Fiona A. Murphy; Steven M. Pollard; Paul M. Brennan; Karl Mechtler; Sarah R. Walmsley

Management of dens fractures in older people and the role of the geriatrician: a survey of practice in UK and Ireland major trauma centres 老年人群齿状突骨折的管理及老年病科医生的作用：一项针对英国和爱尔兰主要创伤中心实践的调查

European Geriatric Medicine

IF3.6

2025-11-20

PREAI

Eleanor Thackeray; Rebecca Hutchins; Frances Rickard; Ester Mikova; Mark Baxter; Paul M. Brennan; Emer Ahern; David JH Shipway

Continuous physiological monitoring for the detection of postoperative deterioration: a protocol for a multistage, multicentre, international, prospective cohort study 术后恶化检测的连续生理监测：一项多阶段、多中心、国际性、前瞻性队列研究的方案

BMJ OPEN

IF2.3

2025-10-06

OAAI

Jiwa, Afra; Cameron, Malcolm M.; Ademuyiwa, Adesoji O.; Adisa, Adewale; Arevalo, Maria Lorena Aguilera; Hessari, Michael Bahrami; Bhangu, Aneel; Brennan, Paul M.; Clark, Neil; Cresswell, Kathrin; Czerwinska, Iwona; D'Adderio, Luciana; Gunn, Eilidh; Haque, Parvez David; Ikegwuonu, Theresa; Lawani, Ismail; Morton, Dion; Nganwa, Audrey; Ntirenganya, Faustin; Pius, Riinu; de la Medina, Antonio Ramos; Samuel, Sangeetha; Shaw, Catherine A.; Tabiri, Stephen; Townsend, Rosie C.; Varghese, Chris; Ghosh, Dhruva; Harrison, Ewen M.

MOLECULAR AND MORPHOLOGICAL FEATURES OF BLOOD VESSELS IN TUMOUR MARGIN REGIONS OF GLIOBLASTOMA ARE DISTINCT FROM TUMOUR CORE AND NORMAL BRAIN, AND DRUG DELIVERY IS REDUCED 胶质母细胞瘤边缘区域的血管分子和形态学特征与肿瘤核心及正常脑组织不同，且药物递送减少。

NEURO-ONCOLOGY

IF13.4

2025-10-01

OAAI

Das, A.; Vallatos, A.; Ireson, C.; Birch, J.; Williams, K.; Strathdee, K.; Littler, C.; Bulbeck, H.; Brunton, V; Brennan, P.; Thompson, G.; Smith, C.; Chalmers, A. J.

Selective regulation and cellular metabolism by the lactate transporter MCT4 in GBM MCT4介导的乳酸转运在GBM中对选择性调节和细胞代谢的作用

Medical Oncology

IF3.5

2025-09-26

PREAI

Sofian Al Shboul; Bingqiao Zhao; Estefania Esposito; Vanessza Fentor; Ashita Singh; Fraser Massie; Ted Hupp; Tessa Moses; Paul M. Brennan; Kathryn Ball; Irena Dapic

Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy 证据表明，在人类进行性核上性麻痹中存在寡聚型tau蛋白的跨突触传播。

Nature Neuroscience

IF20

2025-07-16

OAAI

Robert I. McGeachan; Lois Keavey; Elizabeth M. Simzer; Ya Yin Chang; Jamie L. Rose; Maxwell P. Spires-Jones; Mollie Gilmore; Kristjan Holt; Soraya Meftah; Natalia Ravingerova; Cristina Scutariu; Lewis W. Taylor; Declan King; Makis Tzioras; Jane Tulloch; Sam A. Booker; Imran Liaquat; Nicole Hindley-Pollock; Bethany Geary; Colin Smith; Paul M. Brennan; Claire S. Durrant; Tara L. Spires-Jones

Challenges of combining multimodal data in assessment of people with traumatic brain injury 创伤性脑损伤患者评估中多模态数据融合的挑战

Nature Reviews Neurology

IF33.1

2025-07-11

PREAI

Paul M. Brennan; Graham M. Teasdale

Nanoneedles enable spatiotemporal lipidomics of living tissues 纳米针能够实现活组织的时空脂质组学

Nature Nanotechnology

IF34.9

2025-06-16

OAAI

Chenlei Gu; Davide Alessandro Martella; Leor Ariel Rose; Nadia Rouatbi; Cong Wang; Alaa Zam; Valeria Caprettini; Magnus Jensen; Shiyue Liu; Cathleen Hagemann; Siham Memdouh; Andrea Serio; Vincenzo Abbate; Khuloud T. Al-Jamal; Maddy Parsons; Mads S. Bergholt; Paul M. Brennan; Assaf Zaritsky; Ciro Chiappini

Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies 调节性T细胞耗竭促进髓系细胞活化及胶质母细胞瘤对anti-PD1和肿瘤靶向抗体的反应

Immunity

IF26.3

2025-05-29

OAAI

Felipe Galvez-Cancino; Mariela Navarrete; Gordon Beattie; Simone Puccio; Enrique Conde-Gallastegi; Kane Foster; Yasmin Morris; Teerapon Sahwangarrom; Despoina Karagianni; Jiali Liu; Alvin J.X. Lee; Dimitrios A. Garyfallos; Alexander P. Simpson; Gerasimos-Theodoros Mastrokalos; Francesco Nannini; Cristobal Costoya; Varshaa Anantharam; Beatrice Claudia Cianciotti; Leanne Bradley; Claudia Garcia-Diaz; Melanie Clements; Aditya Shroff; Fatemeh Vahid Dastjerdi; Enrique Miranda Rota; Shahida Sheraz; Robert Bentham; Imran Uddin; Henning Walczak; Alvaro Lladser; James L. Reading; Kerry A. Chester; Martin A. Pule; Paul M. Brennan; Samuel Marguerat; Simona Parrinello; Karl S. Peggs; Nicholas McGranahan; Enrico Lugli; Kevin Litchfield; Steven M. Pollard; Sergio A. Quezada

Surgical Site Infection after Craniotomy in Neuro-Oncology (SINO): A protocol for an international prospective multicentre service evaluation across the United Kingdom and Ireland (vol 20, e0316237, 2025)颅脑肿瘤术后手术部位感染（SINO）：一项在英国和爱尔兰进行的国际前瞻性多中心服务评估方案（卷20，e0316237，2025）

PLOS ONE

IF2.6

2025-05-14

OAAI

Lee, Keng Siang; Borbas, Balint; Chaudhry, Daoud; Kuri, Ashvin; Best, Lawrence; Gillespie, Conor S.; Dehbi, Hakim-Moulay; Aquilina, Kristian; Brennan, Paul; Plaha, Puneet; Ashkan, Keyoumars; Jenkinson, Michael D.; Price, Stephen J.

Phylogenetic divergence of GABAB receptor signaling in neocortical networks over adult life 成年期间新皮质网络中GABAB受体信号通路的系统发育分歧

NATURE COMMUNICATIONS

IF15.7

2025-05-06

OAAI

Wilson, Max A.; Sumera, Anna; Taylor, Lewis W.; Meftah, Soraya; McGeachan, Robert I.; Modebadze, Tamara; Jayasekera, B. Ashan P.; Cowie, Christopher J. A.; LeBeau, Fiona E. N.; Liaquat, Imran; Durrant, Claire S.; Brennan, Paul M.; Booker, Sam A.

Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures 生理性和病理性淀粉样β蛋白在活体人脑片培养中对突触的差异性作用

NATURE COMMUNICATIONS

IF15.7

2025-04-30

OAAI

McGeachan, Robert I.; Meftah, Soraya; Taylor, Lewis W.; Catterson, James H.; Negro, Danilo; Bonthron, Calum; Holt, Kristjan; Tulloch, Jane; Rose, Jamie L.; Gobbo, Francesco; Chang, Ya Yin; Elliott, Jamie; McLay, Lauren; King, Declan; Liaquat, Imran; Spires-Jones, Tara L.; Booker, Sam A.; Brennan, Paul M.; Durrant, Claire S.

Imaging Timing After Surgery for Glioblastoma: Results From an International, Multi-Center Study (INTERVAL-GB)

NEUROSURGERY

IF3.9

2025-04-01

PREAI

Gillespie, Conor; Bligh, Emily; Poon, Michael T. C.; Solomou, Georgios; Islim, Abdurrahman; Millward, Christopher; Rominiyi, Ola; Zakaria, Rasheed; Price, Stephen J.; Watts, Colin; Camp, Sophie; Thompson, Gerard; Mills, Samantha; Waldman, Adam; Booth, Thomas; Brennan, Paul; Jenkinson, Michael D.

研究方向