Xiaoguang Lei - Publications, H-index & Citations

雷

雷晓光 (Xiaoguang Lei)

Peking University

51H指数

318论文数

1.2W被引数

收录论文 161

发表时间

Recent discovery of new enzymes in plant natural product biosynthesis 近期在植物天然产物生物合成中发现的新酶

Current Opinion in Chemical Biology

IF6.1

2026-08-01

PREAI

Zhang, Zheng-Xi; Ke, Han; Wang, Jin; Lei, Xiaoguang

Gut microbiota alters drug metabolism and therapeutic outcomes 肠道微生物群改变药物代谢和治疗效果

Cell Host & Microbe

IF18.7

2026-07-08

PREAI

Fusheng Guo; Yingjie Bai; Xiaoguang Lei

Characterization of the biosynthetic enzymes of the Morus alba benzofuran natural products 白桑苯并呋喃天然产物生物合成酶的表征

Science Advances

IF12.5

2026-06-17

OAAI

Xinshui Yu; Nianxin Guo; Teng Long; Yuling Zhu; Han Ke; Qi Ding; Lei Gao; Xiaoguang Lei

Complete biosynthesis of the anticancer cephalotaxinone and homoerythratine 抗癌三尖杉酯酮和高赤藓碱的完全生物合成

Cell

IF42.5

2026-06-12

PREAI

Runze Tian; Feifan Lin; Nianxin Guo; Chendi Liu; Kaiqi Chen; Yunxi Han; Ruiyun Lan; Qiang Li; Jianbin Yan; Xiaoguang Lei

Proteolysis-Assisted Cyclization Facilitates Site-Centric Target Deconvolution of Isothiocyanates 蛋白酶解辅助环化促进异硫氰酸酯的位点中心目标解卷积

Angewandte Chemie International Edition

IF16.9

2026-05-11

PREAI

Jingyang He; Caiping Tian; Qiang Li; Jian Zhang; Jixiang He; Lingqiang Zhang; Xiaoguang Lei; Jing Yang

Development of a clinically viable MRGPRX4 inverse agonist for cholestatic itch treatment 开发一种临床可行的MRGPRX4反向激动剂用于胆汁淤积性瘙痒的治疗

Nature Chemical Biology

IF13.7

2026-04-09

PREAI

Jun Yang; Ruichao Shen; Chunyu Wang; Wenneng Zhu; Han Ke; Junping Fan; Mengna Zhang; Yingjun Liu; Shuai Li; Guochuan Li; Xiaoming Wang; Yulong Li; Can Cao; Xiaoguang Lei

Structural basis of glucosinolate recognition and transport by plant GTR1 植物GTR1对葡萄糖硫苷的识别和转运的结构基础

Cell Discovery

IF12.5

2026-04-01

OAAI

Yan, Rui; Fan, Junping; Chi, Cheng; Zhang, Bowen; Wu, Di; Chen, Huiwen; Gong, Jianke; Lei, Xiaoguang; Jiang, Daohua

Engineered aldehyde dehydrogenases for amide bond formation 用于酰胺键形成的工程醛脱氢酶

Science

IF45.8

2026-01-29

PREAI

Lei Gao; Xiang Qiu; Jun Yang; Kangdelong Hu; Peilin Li; Wei Li; Feng Gao; Fabrice Gallou; Florian Kleinbeck; Xiaoguang Lei

Structure and mechanism of the human bile acid transporter OSTα–OSTβ 人胆汁酸转运体ostα-ostβ 的结构和机制

Nature

IF48.5

2026-01-28

PREAI

Ke Wang; Junping Fan; Huiwen Chen; Bo Huang; Cheng Chi; Rui Yan; Di Wu; Feng Zhou; Wenhua Zhang; Juquan Jiang; Xiaoguang Lei; Daohua Jiang

CDK10 suppresses nucleic acid sensors-mediated antitumor immunity CDK10抑制核酸传感器介导的抗肿瘤免疫

Nature Cancer

IF28.5

2026-01-08

PREAI

Gaoshan Xu; Fusheng Guo; Chuan He; Xiyong Wang; Bolin Xiang; Lifang Fan; Baoxiang Chen; Jiakun Peng; Yishuang Sun; Jie Shi; Xixin Xing; Yingmeng Yao; Panpan Dai; Haiou Li; Wenjun Xiong; Hudan Liu; Rui Xiao; Guoliang Qing; Congqing Jiang; Baishan Jiang; Xiaoguang Lei; Jinfang Zhang

Total Synthesis of Acoapetaludine A Enabled by a Rhodium-Catalyzed Domino Cyclization 通过铑催化的多米诺环化反应实现Acoapetaludine A的全合成

Journal of the American Chemical Society

IF15.6

2025-12-16

PREAI

Yu Zhang; Liyao Wang; Xiaoguang Lei; Yanxing Jia

Quantitative Reactivity Profiling of Functional Arginine Residues in Human Cancer Cell Line Proteomes 功能性精氨酸残基在人类癌细胞系蛋白质组中的定量反应性分析

Angewandte Chemie International Edition

IF16.9

2025-10-20

PREAI

Wenbo Zhao; Dr. Yuliang Tang; Yihui Gao; Dr. Qi Ding; Dr. Qiang Li; Dr. Wenyang Li; Prof. Dr. Xiaoguang Lei

Author Correction: Alkaline ceramidase 1–mediated platelet ceramide catabolism mitigates vascular inflammation and abdominal aortic aneurysm formation 作者更正：碱性鞘脂酶1介导的血小板鞘脂分解作用减轻血管炎症和腹主动脉瘤形成

cardiovascular research

IF10.8

2025-09-01

PREAI

Xu Zhang; Ze Gong; Yicong Shen; Zeyu Cai; Liu Yang; Tao Zhang; Weihao Li; Yang Zhao; Shirong Zhu; Cihang Liu; Jin Wang; Xian Wang; Ruomei Qi; Junling Liu; Xiaoguang Lei; Wengong Wang; Changtao Jiang; Yi Fu; Wei Kong

Cooperative Photoenzymatic Catalysis for Enantioselective Fluoroalkylation/Cyclization Cascade 协同光酶催化用于手性氟烷基化/环化级联反应

Journal of the American Chemical Society

IF15.6

2025-07-11

PREAI

Dongshan Wu; Sanshan Wang; Haowen Zhang; Han Ke; Zeying Sun; Shuhan Xie; Yihui Gao; Jun Yang; Bingwu Wang; Xiaoguang Lei

Enantioselective Radical Hydrocyanoalkylation of Alkenes via Photoenzymatic Catalysis 通过光酶催化实现烯烃的对映选择性自由基氰基烷基化

JACS Au

IF8.7

2025-07-11

OAAI

Dongshan Wu; Zeying Sun; Sanshan Wang; Jun Yang; Jingyuan He; Xiaoguang Lei

Structural basis of auxin recognition and transport by the plant influx carrier AUX1 植物内向转运载体AUX1介导生长素识别与运输的结构基础

Molecular Plant

IF24.1

2025-06-26

OAAI

Huiwen Chen; Junping Fan; Cheng Chi; Jun Zhao; Di Wu; Xiaoguang Lei; Xing Wang Deng; Daohua Jiang

Decoding 4-vinylanisole biosynthesis and pivotal enzymes in locusts 解码蝗虫中的4-乙烯基苯甲醚生物合成和关键酶

Nature

IF48.5

2025-06-25

OAAI

Xiaojiao Guo; Lei Gao; Shiwei Li; Jing Gao; Yuanyuan Wang; Jing Lv; Jiayi Wei; Jing Yang; Han Ke; Qi Ding; Jun Yang; Fusheng Guo; Haowen Zhang; Xiaoguang Lei; Le Kang

Structural Basis for Inhibition of Urate Reabsorption in URAT1 URAT1尿酸盐重吸收抑制的结构基础

JACS AU

IF8.7

2025-02-23

OAAI

Fan, Junping; Xie, Wenjun; Ke, Han; Zhang, Jing; Wang, Jin; Wang, Haijun; Guo, Nianxin; Bai, Yingjie; Lei, Xiaoguang

Effects of organic salts of virucidal and antiviral compounds from Nelumbo nucifera and Kaempferia parviflora against SARS-CoV-2

SCIENTIFIC REPORTS

IF3.9

2025-02-21

OAAI

Yang, Dan-Dan; Chutiwitoonchai, Nopporn; Wang, Feng; Tian, Ping; Sureram, Sanya; Lei, Xiaoguang; Mahidol, Chulabhorn; Ruchirawat, Somsak; Kittakoop, Prasat

Protein-Affinity Guided Nontargeted Analysis Reveals the Widespread FXR-Antagonistic Pollutants in Surface Water and Source Water Along the Yangtze River and Yellow River 蛋白亲和指导的非靶向分析揭示了长江和黄河地表水及源水中广泛存在的FXR拮抗剂类污染物

ENVIRONMENTAL SCIENCE & TECHNOLOGY

IF11.3

2025-01-27

PREAI

Yang, Yi; Jiao, Ling; Guo, Fusheng; Sun, Yibin; Cui, Hongyang; Lei, Xiaoguang; Hu, Jianying; Wan, Yi