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Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial Iptacopan治疗免疫性血小板减少症和冷凝集素病：一项全球性二期篮式临床研究 Roth, Alexander; Barcellini, Wilma; Ademokun, Christine; Jang, Junho; Lozano, Maria Luisa; Ferreiras, David Valcarcel; Pascual-izquierdo, Cristina; Chitnis, Shripad; Matviykiv, Sofiya; Vitaliti, Alessandra; Chen, Chi; Katsanou, Vasiliki; Chawla, Raghav; Al-samkari, Hanny 分享 收藏
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Ravulizumab demonstrates long-term efficacy, safety and favorable patient survival in patients with paroxysmal nocturnal hemoglobinuria Kulasekararaj, Austin; Brodsky, Robert; Schrezenmeier, Hubert; Griffin, Morag; Roeth, Alexander; Piatek, Caroline; Ogawa, Masayo; Yu, Ji; Patel, Ami S.; Patel, Yogesh; Notaro, Rosario; Usuki, Kensuke; Kulagin, Alexander; Gualandro, Sandra; Fuereder, Wolfgang; Peffault de Latour, Regis; Szer, Jeff; Lee, Jong Wook 分享 收藏
Pharmacokinetic characterization and exposure-response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria Cosson, Valerie; Fu, Rong; Kulasekararaj, Austin; Nishimura, Jun-Ichi; Panse, Jens; Roeth, Alexander; Scheinberg, Phillip; Tong, Hongyan; Yoon, Sung-Soo; Beveridge, Leigh; Gotanda, Keisuke; Jaminion, Felix; Henrich, Andrea; Lundberg, Pontus; Shi, Dayu; Sreckovic, Sasha; Zhang, Yuchen; Zhang, Zilu; Benkali, Khaled; Buatois, Simon 分享 收藏
Phase III COMMODORE 2 and 1 Trials: Characterization of Breakthrough Hemolysis Events in Patients with Nocturnal (PNH) Treated with Crovalimab or Eculizumab III期COMMODORE 2和1试验：接受克罗瓦利马布或依库珠单抗治疗的阵发性夜间血红蛋白尿症（PNH）患者突破性溶血事件的表征 Kulasekararaj, Austin G.; Czyz, Jaroslaw; Flynn, Catherine; Gastal, Gabriela Roncone; Hus, Marek; Lalayanni, Chrysavgi; Nur, Erfan; Scheinberg, Phillip; Ueda, Yasutaka; Vannucchi, Alessandro Maria; Vicente, Maria Vidriales; Viigimaa, Iige; Buatois, Simon; Chang, Alice C.; Chebon, Sammy; Roeth, Alexander 分享 收藏
Phase III Randomized COMMODORE 2 Trial: 2-Year Efficacy and Safety of Crovalimab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Naive to Complement Inhibition III期随机COMMODORE 2试验：Crovalimab在未接受补体抑制治疗的阵发性夜间血红蛋白尿（PNH）患者中的2年疗效与安全性 Roeth, Alexander; He, Guangsheng; Brodsky, Andres; Chai-Adisaksopha, Chatree; Comia, Narcisa Sonia; Gaya, Anna; Hoeglund, Martin; Kelly, Richard J.; Kori, Ahlam Naila; Lee, Je-Hwan; Obara, Naoshi; Risitano, Antonio M.; Appius, Anita; Beveridge, Leigh; Gentile, Brittany; Zhang, Zilu; Han, Bing; Sreckovic, Sasha 分享 收藏
Iptacopan Monotherapy in Patients with Cold Agglutinin Disease: Phase II Study Results Iptacopan单药治疗冷凝集素病：II期研究结果 Roeth, Alexander; Barcellini, Wilma; Ademokun, Christine; Chitnis, Shripad; Matviykiv, Sofiya; Vitaliti, Alessandra; Chen, Chi; Katsanou, Vasiliki; Chawla, Raghav; Al-Samkari, Hanny 分享 收藏
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Sustained improvements in patient-reported outcomes after long-term sutimlimab in patients with cold agglutinin disease: results from the CADENZA study open-label extension Roeth, Alexander; Broome, Catherine M.; Barcellini, Wilma; Jilma, Bernd; Hill, Quentin A.; Cella, David; Tvedt, Tor Henrik Anderson; Yamaguchi, Masaki; Murakhovskaya, Irina; Lee, Michelle; Shafer, Frank; Wardecki, Marek; Jayawardene, Deepthi; Yoo, Ronnie; Msihid, Jerome; Weitz, Ilene C. 分享 收藏
Long-term efficacy and safety of continued complement C1s inhibition with sutimlimab in cold agglutinin disease: CADENZA study Part B Roeth, Alexander; Berentsen, Sigbjorn; Barcellini, Wilma; D'Sa, Shirley; Jilma, Bernd; Michel, Marc; Weitz, Ilene C.; Yamaguchi, Masaki; Nishimura, Jun-ichi; Vos, Josephine M. I.; Cid, Joan; Storek, Michael; Wong, Nancy; Yoo, Ronnie; Jayawardene, Deepthi; Srivastava, Shruti; Wardecki, Marek; Shafer, Frank; Lee, Michelle; Broome, Catherine M. 分享 收藏
Phase 3 randomized COMMODORE 2 trial: Crovalimab versus eculizumab in patients with paroxysmal nocturnal hemoglobinuria naive to complement inhibition Roeth, Alexander; He, Guangsheng; Tong, Hongyan; Lin, Zenghua; Wang, Xiaoqin; Chai-Adisaksopha, Chatree; Lee, Je-Hwan; Brodsky, Andres; Hantaweepant, Chattree; Dumagay, Teresita E.; Demichelis-Gomez, Roberta; Rojnuckarin, Ponlapat; Sun, Jing; Hoeglund, Martin; Jang, Jun Ho; Gaya, Anna; Silva, Fernando; Obara, Naoshi; Kelly, Richard J.; Beveridge, Leigh; Buatois, Simon; Chebon, Sammy; Gentile, Brittany; Lundberg, Pontus; Sreckovic, Sasha; Nishimura, Jun-ichi; Risitano, Antonio; Han, Bing 分享 收藏
Safety and Efficacy of Pegcetacoplan in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria over 48 Weeks: 307 Open-Label Extension Study Patriquin, Christopher J.; Bogdanovic, Andrija; Griffin, Morag; Kelly, Richard J.; Maciejewski, Jaroslaw P.; Mulherin, Brian; de Latour, Regis Peffault; Roeth, Alexander; Selvaratnam, Veena; Szer, Jeffrey; Al-Adhami, Mohammed; Horneff, Regina; Tan, Lisa; Yeh, Michael; Panse, Jens 分享 收藏
Sutimlimab improves quality of life in patients with cold agglutinin disease: results of patientreported outcomes from the CARDINAL study (vol 101, pg 2169, 2022) Roeth, Alexander; Barcellini, Wilma; Tvedt, Tor Henrik Anderson; Miyakawa, Yoshitaka; Kuter, David J.; Su, Jun; Jiang, Xiaoyu; Hobbs, William; Morales, Jaime; Shafer, Frank; Weitz, Ilene C. 分享 收藏
Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria de Latour, Regis Peffault; Roeth, Alexander; Kulasekararaj, Austin G.; Han, Bing; Scheinberg, Phillip; Maciejewski, Jaroslaw P.; Ueda, Yasutaka; de Castro, Carlos M.; Di Bona, Eros; Fu, Rong; Zhang, Li; Griffin, Morag; Langemeijer, Saskia M. C.; Panse, Jens; Schrezenmeier, Hubert; Barcellini, Wilma; Mauad, Vitor A. Q.; Schafhausen, Philippe; Tavitian, Suzanne; Beggiato, Eloise; Chew, Lee Ping; Gaya, Anna; Huang, Wei-Han; Jang, Jun Ho; Kitawaki, Toshio; Kutlar, Abdullah; Notaro, Rosario; Pullarkat, Vinod; Schubert, Joerg; Terriou, Louis; Uchiyama, Michihiro; Wong Lee Lee, Lily; Yap, Eng-Soo; Sicre de Fontbrune, Flore; Marano, Luana; Alashkar, Ferras; Gandhi, Shreyans; Trikha, Roochi; Yang, Chen; Liu, Hui; Kelly, Richard J.; Hoechsmann, Britta; Kerloeguen, Cecile; Banerjee, Partha; Levitch, Rafael; Kumar, Rakesh; Wang, Zhixin; Thorburn, Christine; Maitra, Samopriyo; Li, Shujie; Verles, Aurelie; Dahlke, Marion; Risitano, Antonio M. 分享 收藏
High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA): a single-arm, phase 2 trial Schorb, Elisabeth; Isbell, Lisa Kristina; Kerkhoff, Andrea; Mathas, Stephan; Braulke, Friederike; Egerer, Gerlinde; Roeth, Alexander; Schliffke, Simon; Borchmann, Peter; Brunnberg, Uta; Kroschinsky, Frank; Moehle, Robert; Rank, Andreas; Wellnitz, Dominique; Kasenda, Benjamin; Pospiech, Lisa; Wendler, Julia; Scherer, Florian; Deckert, Martina; Henkes, Elina; von Gottberg, Philipp; Gmehlin, Dennis; Backenstrass, Matthias; Jensch, Antje; Burger-Martin, Elvira; Grishina, Olga; Fricker, Heidi; Malenica, Natalie; Orban, Andras; Duyster, Justus; Ihorst, Gabriele; Finke, Juergen; Illerhaus, Gerald 分享 收藏
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