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O

Ophir D. Klein

University of California, San Francisco

67H指数
371论文数
1.6W被引数
收录论文 158
发表时间
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Building and regenerating intestines by manipulating intestinal stem cells通过调控肠道干细胞构建和再生肠道
errNature Reviews Gastroenterology & Hepatology
IF51
err2026-09-03
err0
PREAI
errCalvin J. Kuo; Sarah Blutt; Mark Donowitz; Mary K. Estes; Chandan Guha; Ophir D. Klein; Linheng Li; Joyce C. Niland; António J. M. Santos; Ramesh A. Shivdasani; Jason R. Spence; Carol J. Swanson; Timothy C. Wang; Kelley S. Yan; Nicholas C. Zachos; Michael A. Helmrath
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Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry通过光响应水凝胶的顺序图案化引导隐窝分裂并揭示上皮曲率对分裂对称性的作用
errAdvanced Science
IF14.1
err2026-08-29
err0
errOAAI
errDelaney L. McNally; Kaustav Bera; Nolan R. Petrich; Alex Khang; Marilyne Coulombe; David Castillo-Azofeifa; Ophir D. Klein; Peter J. Dempsey; Kristi S. Anseth
err分享
err收藏
Shared genetic basis and structure of syndromic and normal facial variation综合征性及正常面部变异共享的遗传基础与结构
errAmerican Journal of Human Genetics
IF8.1
err2026-08-21
err0
PREAI
errJ. David Aponte; Cassidy Da Silva; Hanne Hoskens; Seppe Goovaerts; Michiel Vanneste; Jay Devine; Katherine Caine; Alexander Buchner Beaudet; H. Artee Luchman; Seth M. Weinberg; Hilde Peeters; Ophir D. Klein; Ralph S. Marcucio; A. Micheil Innes; Peter Claes; Richard A. Spritz; Francois P. Bernier; Benedikt Hallgrímsson
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Mapping mesenchymal diversity in the human small intestine and organoids在人类小肠和类器官中绘制间充质多样性
errNature Cell Biology
IF19.1
err2026-07-22
err0
errOAAI
errKelli F. Johnson; Xiangning Dong; Yu-Hwai Tsai; Angeline Wu; Sydney G. Clark; Abigail Vallie; Sha Huang; Charlie J. Childs; Rachel K. Zwick; Ian Glass; Katherine D. Walton; Ophir D. Klein; Jason R. Spence
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Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility微生物组产生的烟酸调控结肠区域性特征和损伤易感性
errCell
IF42.5
err2026-03-10
err0
PREAI
errJérémie Rispal; Jasmine R. Garcia; Brisa Palikuqi; Manasa Vegesna; Dedeepya Vaka; Seung Woo Kang; Coralie Trentesaux; Juan Du; Nicola R. Realini; Paige N. Spencer; James M. Gardner; Annika Hausmann; Michael G. Kattah; Ken S. Lau; Dario Boffelli; Ophir D. Klein
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Decoding epithelial regeneration in the cornea: multi-omic analysis reveals cellular plasticity as central mechanism解码角膜上皮再生的机制：多组学分析揭示细胞可塑性作为核心机制
errCellular & Molecular Biology Letters
IF10.2
err2025-11-03
err0
errOAAI
errNadège Feret; Alicia Caballero Megido; Alison Kuony; Pauline Marangoni; Laura Fichter; Sonia Garcia Llorens; Aurore Attina; Naima Nhiri; Eric Jacquet; Jerome Vialaret; Vincent Daien; Alexandre David; Christophe Hirtz; Karine Loulier; Ophir D. Klein; Frederic Michon
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Identification of Novel and Rare Gene Variants in Cleft Lip/Palate Patients From Kuwaiti Consanguineous Families by Exome Sequencing通过外显子测序鉴定来自科威特近亲婚配家庭的唇裂/腭裂患者中的新型和稀有基因变异
errAmerican Journal of Medical Genetics Part A
IF1.7
err2025-10-01
err0
PREAI
errAlkharafi, Lateefa; Al-Bustan, Suzanne; Alkanderi, Sumaya; Elshafie, Reem M.; Dannoun, Heba; Alrohaif, Hadil; Elshafey, Alaa-Eldin; Alwadani, Amal; Alhasawi, Saud; Aljeraiwi, Nour; Alotaibi, Khaled; Hamdan, Hala; Vaka, Dedeepya; Hodoglugil, Ugur; Boffelli, Dario; Perez, Kimberly K. Diaz; Leslie-Clarkson, Elizabeth J.; Klein, Ophir D.
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err收藏
IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunityIL-25诱导的记忆性2型先天淋巴细胞增强黏膜免疫
errCell
IF42.5
err2025-09-05
err0
errOAAI
errVictor S. Cortez; Sara Viragova; Satoshi Koga; Meizi Liu; Claire E. O’Leary; Roberto R. Ricardo-Gonzalez; Andrew W. Schroeder; Nathan Kochhar; Dedeepya Vaka; Dario Boffelli; Ophir D. Klein; Michael S. Diamond; Hong-Erh Liang; Richard M. Locksley
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err收藏
Growth arrest specific–6 and angiotoxin receptor–like signaling drive oral regenerative wound repair生长停滞特异性-6和血管毒素受体样信号驱动口腔再生性伤口修复
errScience Translational Medicine
IF14.6
err2025-07-02
err0
PREAI
errMichelle F. Griffin; Jessica Cook; Annah Morgan; Dario Boffelli; Mauricio Downer; Amanda F. Spielman; Nicholas J. Guardino; Jason L. Guo; Jennifer B. L. Parker; Michael Januszyk; Caleb Valencia; Maxwell Kuhnert; John Lu; Rachel Zwick; Derrick C. Wan; Ophir D. Klein; Michael T. Longaker
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err收藏
Partially differentiated ileal and distal-colonic human F508del-cystic fibrosis-enteroids secrete fluid in response to forskolin and linaclotide部分分化的回肠和远端结肠人F508del-囊性纤维化类器官对 forskolin 和 linaclotide 的刺激产生液体分泌
errISCIENCE
IF4.1
err2025-05-01
err0
errOAAI
errRong, Yan; Zhang, Zixin; de Jonge, Hugo R.; Lin, Ruxian; Yu, Huimin; Sarker, Rafiq; Boffelli, Dario; Zwick, Rachel K.; Klein, Ophir D.; Tse, Chung-Ming; Donowitz, Mark; Singh, Varsha
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p75 neurotrophin receptor regulates craniofacial growth and morphology in postnatal developmentp75神经生长因子受体在出生后发育中调控颅面生长和形态。
errFRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
IF4.3
err2025-03-18
err0
errOAAI
errZhao, Byron; Suh, Jinsook; Zhang, Yan; Yin, Eric; Kadota-Watanabe, Chiho; Chang, In Won; Yaung, Jun; Lao-Ngo, Isabelle; Young, Nathan M.; Kim, Reuben H.; Klein, Ophir D.; Hong, Christine
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Synthetic organizer cells guide development via spatial and biochemical instructions合成组织者细胞通过空间和生化指令引导发育
errCELL
IF42.5
err2025-02-01
err0
PREAI
errYamada, Toshimichi; Trentesaux, Coralie; Brunger, Jonathan M.; Xiao, Yini; Stevens, Adam J.; Martyn, Iain; Kasparek, Petr; Shroff, Neha P.; Aguilar, Angelica; Bruneau, Benoit G.; Boffelli, Dario; Klein, Ophir D.; Lim, Wendell A.
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A 3D Clinical Face Phenotype Space of Genetic Syndromes Using a Triplet-Based Singular Geometric Autoencoder
errIEEE ACCESS
IF3.6
err2025-01-01
err0
errOAAI
errMahdi, Soha S.; Caldeira, Eduarda; Matthews, Harold; Vanneste, Michiel; Nauwelaers, Nele; Yuan, Meng; Bouritsas, Giorgos; Baynam, Gareth S.; Hammond, Peter; Spritz, Richard; Klein, Ophir D.; Bronstein, Michael; Hallgrimsson, Benedikt; Peeters, Hilde; Claes, Peter
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Syndrome-informed phenotyping identifies a polygenic background for achondroplasia-like facial variation in the general population
errNATURE COMMUNICATIONS
IF15.7
err2024-12-02
err0
errOAAI
errVanneste, Michiel; Hoskens, Hanne; Goovaerts, Seppe; Matthews, Harold; Devine, Jay; Aponte, Jose D.; Cole, Joanne; Shriver, Mark; Marazita, Mary L.; Weinberg, Seth M.; Walsh, Susan; Richmond, Stephen; Klein, Ophir D.; Spritz, Richard A.; Peeters, Hilde; Hallgrimsson, Benedikt; Claes, Peter
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Bank vole genomics links determinate and indeterminate growth of teeth
errBMC GENOMICS
IF3.7
err2024-10-30
err0
PREAI
errCalamari, Zachary T.; Song, Andrew; Cohen, Emily; Akter, Muspika; Roy, Rishi Das; Hallikas, Outi; Christensen, Mona M.; Li, Pengyang; Marangoni, Pauline; Jernvall, Jukka; Klein, Ophir D.
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Multiple endocrine defects in adult-onset Sprouty1/2/4 triple knockout mice
errSCIENTIFIC REPORTS
IF3.9
err2024-08-22
err0
errOAAI
errAltes, Gisela; Olomi, Anna; Perramon-Guell, Aida; Hernandez, Sara; Casanovas, Anna; Perez, Aurora; Diaz-Tocados, Juan Miguel; Valdivielso, Jose Manuel; Megino, Cristina; Navaridas, Raul; Matias-Guiu, Xavier; Klein, Ophir D.; Egea, Joaquim; Dolcet, Xavi; Yeramian, Andree; Encinas, Mario
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Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy
errCANCER DISCOVERY
IF33.3
err2024-05-10
err1
PREAI
errChoudhury, Abrar; Cady, Martha A.; Lucas, Calixto-Hope G.; Najem, Hinda; Phillips, Joanna J.; Palikuqi, Brisa; Zakimi, Naomi; Joseph, Tara; Birrueta, Janeth O.; Chen, William C.; Bush, Nancy A. Oberheim; Hervey-Jumper, Shawn L.; Klein, Ophir D.; Toedebusch, Christine M.; Horbinski, Craig M.; Magill, Stephen T.; Bhaduri, Aparna; Perry, Arie; Dickinson, Peter J.; Heimberger, Amy B.; Ashworth, Alan; Crouch, Elizabeth E.; Raleigh, David R.
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Sprouty genes regulate activated fibroblasts in mammary epithelial development and breast cancer
errCELL DEATH & DISEASE
IF9.6
err2024-04-10
err0
errOAAI
errLi, Jiyong; Ma, Rongze; Wang, Xuebing; Lu, Yunzhe; Chen, Jing; Feng, Deyi; Zhou, Jiecan; Xia, Kun; Klein, Ophir; Xie, Hao; Lu, Pengfei
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err收藏
Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development
errNATURE CELL BIOLOGY
IF19.1
err2024-04-03
err4
PREAI
errShroff, Neha Pincha; Xu, Pengfei; Kim, Sangwoo; Shelton, Elijah R.; Gross, Ben J.; Liu, Yucen; Gomez, Carlos O.; Ye, Qianlin; Drennon, Tingsheng Yu; Hu, Jimmy K.; Green, Jeremy B. A.; Campas, Otger; Klein, Ophir D.
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Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
errNATURE CELL BIOLOGY
IF19.1
err2024-02-06
err5
errOAAI
errZwick, Rachel K.; Kasparek, Petr; Palikuqi, Brisa; Viragova, Sara; Weichselbaum, Laura; McGinnis, Christopher S.; McKinley, Kara L.; Rathnayake, Asoka; Vaka, Dedeepya; Nguyen, Vinh; Trentesaux, Coralie; Reyes, Efren; Gupta, Alexander R.; Gartner, Zev J.; Locksley, Richard M.; Gardner, James M.; Itzkovitz, Shalev; Boffelli, Dario; Klein, Ophir D.
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研究方向

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合作学者
合作期刊
C
Charles M. Perou
H 指数: 193 · 论文数: 2.0K
P
Peter Carmeliet
H 指数: 192 · 论文数: 1.4K
M
Michael G. Rosenfeld
H 指数: 169 · 论文数: 491
E
Elaine Fuchs
H 指数: 168 · 论文数: 526
Z
Zena Werb
H 指数: 168 · 论文数: 581
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