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J

Jason Moffat

University of Bonn

73H指数
599论文数
3.1W被引数
收录论文 174
发表时间
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Cell volume regulation in metazoans involves phosphorylation of TSC22D proteins多细胞动物中的细胞体积调节涉及TSC22D蛋白的磷酸化
errCell Reports
IF6.9
err2026-09-24
err0
errOAAI
errSeon Yong Lee; Yu-Xi Xiao; Magali Aguilera-Uribe; Saba Birkadze; Patricia Mero; Kevin R. Brown; Nga H. Nguyen; John M. Pleinis; Aylin R. Rodan; Arohan R. Subramanya; Jason Moffat
err分享
err收藏
A genome-wide functional analysis of conserved intronic regions reveals essential roles for speckle-associated retained introns全基因组功能分析揭示保守内含子区域中与核斑相关保留内含子的关键作用
errCell Reports
IF6.9
err2026-07-20
err0
errOAAI
errShaghayegh Farhangmehr; Ulrich Braunschweig; Mingkun Wu; Syed Nabeel-Shah; Kevin R. Brown; Jacob L. Fine; Jason Moffat; Benjamin J. Blencowe
err分享
err收藏
uPAR is highly expressed in recurrent glioblastoma and represents a candidate CAR T cell targetuPAR在复发性胶质母细胞瘤中高表达，并代表CAR T细胞候选靶点
errScience Translational Medicine
IF14.6
err2026-05-13
err0
PREAI
errWilliam T. Maich; Muhammad Vaseem Shaikh; Anish Puri; Martin A. Rossotti; Shan Grewal; Aapti Khanna; Alisha Anand; Nicholas Mikolajewicz; Mathieu P. Seyfrid; Dillon A. McKenna; Minomi Subapanditha; Daniel Mobilio; Greg Hussack; Joey G. Sheff; Jennifer J. Hill; Mo Taleb; Jacek M. Kwiecien; Sabra Salim; Neil Savage; Bill Wang; Sunjay Sharma; Abdelsimar Omar; Chirayu Chokshi; Kui Zhai; Shawn C. Chafe; Jason Moffat; Thomas Kislinger; Chitra Venugopal; Kevin A. Henry; Sheila K. Singh
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Orobas: A computational approach for scoring and analysis of quantitative chemical-genetic interactions from CRISPR-Cas9 screensOrobas：一种用于对来自CRISPR-Cas9筛选的定量化学生物学相互作用进行评分和分析的计算方法
errSTAR Protocols
IF1.3
err2026-05-01
err0
PREAI
errHassan, Arshia Z.; Zhang, Xiang; Ward, Henry N.; Billmann, Maximilian; Bajjali, Salem; Brown, Kevin R.; Bhojoo, Urvi; Chan, Katherine; Lin, Kevin; Costanzo, Michael; Andrews, Brenda; Boone, Charles; Moffat, Jason; Myers, Chad L.
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Splice isoform-perturbation coupled to single cell transcriptome profiling reveals functions of microexons in neurogenesis and autism-linked pathways剪接同工型扰动与单细胞转录组分析相结合，揭示了微外显子在神经发生和自闭症相关途径中的功能
errNature Communications
IF15.7
err2026-02-03
err0
errOAAI
errSteven J. Dupas; Guillermo E. Parada; Jack Daiyang Li; Kevin R. Brown; Jason Moffat; Benjamin J. Blencowe
err分享
err收藏
27 GENETIC SCREENING REVEALS FEN1 AS A DRIVER OF STEMNESS AND TEMOZOLOMIDE RESISTANCE IN GLIOBLASTOMA27 基因筛查揭示FEN1是胶质母细胞瘤中维持干细胞特性及替莫唑胺耐药性的驱动因子
errNeuro-Oncology Advances
IF4.1
err2025-08-31
err0
errOAAI
errBenjamin A Brakel; Dillon McKenna; Ali Saleh; Anish Puri; Vaseem Muhammad Shaikh; Manoj Singh; Nicholas Mikolajewicz; Marcello Beltrami; Alisha Anand; Petar Miletic; Kevin R Brown; David Tieu; Abdo-jose Tomajian; William Maich; Sabra Salim; Yujin Suk; Minomi Subapanditha; Deena Gendoo; Chitra Venugopal; Jason Moffat; Sachin Katyal; Sheila K Singh; Chirayu R Chokshi
err分享
err收藏
A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis全基因组范围内的体内CRISPR激活筛选确定了BACE1作为肺癌脑转移的 therapeutic vulnerability。
errScience Translational Medicine
IF14.6
err2025-07-02
err0
PREAI
errShawn C. Chafe; Kui Zhai; Nikoo Aghaei; Petar Miletic; Zhi Huang; Kevin R. Brown; Daniel Mobilio; Daniel Young; Yujin Suk; Shan Grewal; Dillon McKenna; Zahra Alizada; Agata M. Kieliszek; Fred C. Lam; Laura Escudero; Qian Huang; Ariana Huebner; Jack Lu; Patrick Ang; Alisha Anand; Stefan Custers; Erika Apel; Sarah Slassi; Benjamin Brakel; Jongmyung Kim; James K. C. Liu; Blessing Iquo Bassey-Archibong; Rober Abdo; Yaron Shargall; Jian-Qiang Lu; Jean-Claude Cutz; Qi Zhang; Shawn Shun-Cheng Li; Chitra Venugopal; Robert E. Hynds; Antoine Dufour; Jason Moffat; Charles Swanton; Shideng Bao; Sheila K. Singh
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Tegavivint triggers TECR-dependent nonapoptotic cancer cell deathTegavivint 触发 TECR 依赖性的非凋亡性癌细胞死亡
errNATURE CHEMICAL BIOLOGY
IF13.7
err2025-05-26
err0
PREAI
errLeak, Logan; Wang, Ziwei; Joseph, Alby J.; Johnson, Brianna; Chan, Alyssa A.; Decosto, Cassandra M.; Magtanong, Leslie; Ko, Pin-Joe; Lee, Weaverly Colleen; Ritho, Joan; Manukian, Sophia; Millner, Alec; Chitkara, Shweta; Salinas, Jennifer J.; Skouta, Rachid; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Myers, Chad L.; Moffat, Jason; Boone, Charles; Bensinger, Steven J.; Nathanson, David A.; Atilla-Gokcumen, G. Ekin; Moding, Everett J.
err分享
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Discovering nanoparticle corona ligands for liver macrophage capture发现用于捕获肝脏巨噬细胞的纳米颗粒冠层配体
errNATURE NANOTECHNOLOGY
IF34.9
err2025-05-15
err0
PREAI
errBussin, Bram; MacDuff, Marshall G. G.; Ngo, Wayne; Wu, Jamie L. Y.; Lin, Zachary P.; Farias, Adrian Granda; Stordy, Benjamin; Sepahi, Zahra; Ahmed, Sara; Moffat, Jason
err分享
err收藏
Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation
errSTEM CELL REPORTS
IF5.1
err2025-02-01
err0
errOAAI
errChidiac, Rony; Yang, Andy; Kubarakos, Elli; Mikolajewicz, Nicholas; Han, Hong; Almeida, Maira P.; Thibeault, Pierre E.; Lin, Sichun; Macleod, Graham; Gratton, Jean-Philippe; Moffat, Jason; Angers, Stephane
err分享
err收藏
Functional profiling of murine glioma models highlights targetable immune evasion phenotypes
errACTA NEUROPATHOLOGICA
IF9.3
err2024-11-27
err0
errOAAI
errMikolajewicz, Nicholas; Tatari, Nazanin; Wei, Jiarun; Savage, Neil; Farias, Adrian Granda; Dimitrov, Vassil; Chen, David; Zador, Zsolt; Dasgupta, Kuheli; Aguilera-Uribe, Magali; Xiao, Yu-Xi; Lee, Seon Yong; Mero, Patricia; Mckenna, Dillon; Venugopal, Chitra; Brown, Kevin R.; Han, Hong; Singh, Sheila; Moffat, Jason
err分享
err收藏
THERAPEUTIC TARGETING OF MISLOCALIZED NUCLEAR ENVELOPE PROTEINS INMYC-DRIVEN GROUP 3 MEDULLOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errSuk, Yujin; Ibanez-Vega, Jorge; Chaudhry, Iqra; Rossotti, Martin; Subapanditha, Minomi; Miletic, Petar; Custers, Stefan; Escudero, Laura; Delaidelli, Alberto; Nakashima, Takuma; Xiao, Yuxi; Moffat, Jason; Suzuki, Hiromichi; Sorensen, Poul; Henry, Kevin; Venugopal, Chitra; Krenciute, Giedre; Singh, Sheila
err分享
err收藏
TARGETING AXONAL GUIDANCE DEPENDENCIES IN GLIOBLASTOMA WITH ROBO1 CAR T CELLS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errChokshi, Chirayu; Brakel, Benjamin; Shaikh, Muhammad Vaseem; Rossotti, Martin A.; Venugopal, Chitra; Brown, Kevin R.; Henry, Kevin A.; Moffat, Jason; Singh, Sheila K.
err分享
err收藏
ENHANCING GLIOBLASTOMA TREATMENT: ALLOGENEIC CAR-T CELLS OVERCOMES FUNCTIONAL DEFICITS OF PATIENT-DERIVED AUTOLOGOUS PRODUCTS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errShaikh, Muhammad Vaseem; Salim, Sabra K.; Maich, William T.; Ananad, Alisha; Wei, Jeffrey; Subapanditha, Minomi K.; Suk, Yujin; Singh, Manoj; Tabunshchyk, Zoya; Chen, Katie; Vora, Parvez; Venugopal, Chitra; Moffat, Jason; Singh, Sheila K.
err分享
err收藏
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells
errNATURE MEDICINE
IF50
err2024-08-02
err0
PREAI
errChokshi, Chirayu R.; Shaikh, Muhammad Vaseem; Brakel, Benjamin; Rossotti, Martin A.; Tieu, David; Maich, William; Anand, Alisha; Chafe, Shawn C.; Zhai, Kui; Suk, Yujin; Kieliszek, Agata M.; Miletic, Petar; Mikolajewicz, Nicholas; Chen, David; Mcnicol, Jamie D.; Chan, Katherine; Tong, Amy H. Y.; Kuhlmann, Laura; Liu, Lina; Alizada, Zahra; Mobilio, Daniel; Tatari, Nazanin; Savage, Neil; Aghaei, Nikoo; Grewal, Shan; Puri, Anish; Subapanditha, Minomi; Mckenna, Dillon; Ignatchenko, Vladimir; Salamoun, Joseph M.; Kwiecien, Jacek M.; Wipf, Peter; Sharlow, Elizabeth R.; Provias, John P.; Lu, Jian-Qiang; Lazo, John S.; Kislinger, Thomas; Lu, Yu; Brown, Kevin R.; Venugopal, Chitra; Henry, Kevin A.; Moffat, Jason; Singh, Sheila K.
err分享
err收藏
The TSC22D , WNK , and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
errCELL REPORTS
IF6.9
err2024-07-01
err2
errOAAI
errXiao, Yu -Xi; Lee, Seon Yong; Aguilera-Uribe, Magali; Samson, Reuben; Au, Aaron; Khanna, Yukti; Liu, Zetao; Cheng, Ran; Aulakh, Kamaldeep; Wei, Jiarun; Farias, Adrian Granda; Reilly, Taylor; Birkadze, Saba; Habsid, Andrea; Brown, Kevin R.; Chan, Katherine; Mero, Patricia; Huang, Jie Qi; Billmann, Maximilian; Rahman, Mahfuzur; Myers, Chad; Andrews, Brenda J.; Youn, Ji-Young; Yip, Christopher M.; Rotin, Daniela; Derry, W. Brent; Forman-Kay, Julie d.; Moses, Alan M.; Pritisanac, Iva; Gingras, Anne-Claude; Moffat, Jason
err分享
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Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
errCELL REPORTS
IF6.9
err2024-05-01
err3
errOAAI
errDhaliwal, Navroop K.; Weng, Octavia Yifang; Dong, Xiaoxue; Bhattacharya, Afrin; Ahmed, Mai; Haruka, Nishimura; Choi, Wendy W. Y.; Aggarwal, Aditi; Luikart, Bryan W.; Shu, Qiang; Li, Xuekun; Wilson, Michael D.; Moffat, Jason; Wang, Lu-Yang; Muffat, Julien; Li, Yun
err分享
err收藏
Salmonella exploits membrane reservoirs for invasion of host cells
errNATURE COMMUNICATIONS
IF15.7
err2024-04-10
err5
errOAAI
errZhu, Hongxian; Sydor, Andrew M.; Boddy, Kirsten C.; Coyaud, Etienne; Laurent, Estelle M. N.; Au, Aaron; Tan, Joel M. J.; Yan, Bing-Ru; Moffat, Jason; Muise, Aleixo M.; Yip, Christopher M.; Grinstein, Sergio; Raught, Brian; Brumell, John H.
err分享
err收藏
Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-04-08
err2
errOAAI
errNi, Zuyao; Ahmed, Nujhat; Nabeel-Shah, Syed; Guo, Xinghua; Pu, Shuye; Song, Jingwen; Marcon, Edyta; Burke, Giovanni L.; Tong, Amy Hin Yan; Chan, Katherine; Ha, Kevin C. H.; Blencowe, Benjamin J.; Moffat, Jason; Greenblatt, Jack F.
err分享
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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability全基因组CRISPR筛选鉴定野生型和突变型p53稳定性的新型调节因子
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2024-04-05
err2
errOAAI
errLu, YiQing; Cho, Tiffany; Mukherjee, Saptaparna; Suarez, Carmen Florencia; Gonzalez-Foutel, Nicolas S.; Malik, Ahmad; Martinez, Sebastien; Dervovic, Dzana; Oh, Robin Hyunseo; Langille, Ellen; Al-Zahrani, Khalid N.; Hoeg, Lisa; Lin, Zhen Yuan; Tsai, Ricky; Mbamalu, Geraldine; Rotter, Varda; Ashton-Prolla, Patricia; Moffat, Jason; Chemes, Lucia Beatriz; Gingras, Anne-Claude; Oren, Moshe; Durocher, Daniel; Schramek, Daniel
err分享
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