Yu Chen - Publications, H-index & Citations

陈瑜 (Yu Chen)

Sanofi

66H指数

555论文数

3.0W被引数

收录论文 143

发表时间

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid-Derived Ionizable Lipids and Device Engineering 一种用于开发鲁棒性肺 mRNA 递送的整体平台方法：整合新型酚酸衍生的可电离脂质和设备工程

Advanced Functional Materials

IF19

2026-09-08

OAAI

Neha Kaushal; Younan Ma; Asad Khanmohammed; Dipen Parande; Hanming Zhang; Saket Dolare; Juliet Chen; Apiwat Wangweerawong; Saswata Karmakar; Hongfeng Deng; Frank Koppenhagen; Shraddha Sharma; Eric Reyes; Sherry He; Lianne Boeglin; Caroline Woo; Azadeh Paksa; Ayed Allawzi; Anusha Dias; Gregory Troiano; Shrirang Karve; Frank DeRosa

A dependency map enhanced with next-generation 3D cancer models 一张融合了新一代3D癌症模型的药物靶点互作图

Nature

IF48.5

2026-08-05

OAAI

James V. Neiswender; Samuel Maffa; Lisa Brenan; Dina ElHarouni; Yejie Yun; Isabella Boyle; Kirsty Wienand; Haider Inam; Tate Bertea; Ashley Anderson; Megan Wong; Matias Enriquez; Evan Lenz; Beatriz Villafranca; Nora Shanks; Mary Hager; Nia Lloyd; Hannah Shadmany; Sarah J. Wie; Harry Liang; Konnor Yunghans; Xiaomeng Zhang; Lauren Golden; Hannah Harris; Serena Day; Philip Montgomery; Samantha Stokes; Ross M. Giglio; Cynthia Hajal; James R. Whittle; Guadalupe Garcia; Caitlin E. Mills; Mehdi Touat; Kristine Pelton; Hongyu Li; Prem Sai Prabhakar; Sonja Herter; Zoe Hoffmann Kamrat; Dan Gui; Julien Dilly; Chen Khuan Wong; Jimmy A. Guo; Sangita Pal; Yossef Baidi; Ryan Johnston; Daniel D. Brown; Sonam Bhatia; Peter S. Winter; Srivatsan Raghavan; Rameen Beroukhim; Eva Colas; David L. Spector; Adam J. Bass; Peter K. Sorger; Yu Chen; Sarah J. Hill; Steffi Oesterreich; Adrian V. Lee; Himisha Beltran; Jesse S. Boehm; Yuen-Yi Tseng; David E. Root; William C. Hahn; Andrew J. Aguirre; Catarina D. Campbell; Keith L. Ligon; Joshua M. Dempster; Tsukasa Shibue; Francisca Vazquez

NSD2 targeting reverses plasticity and drug resistance in prostate cancer NSD2靶向逆转前列腺癌的细胞可塑性和药物抵抗性

Nature

IF48.5

2025-11-26

OAAI

Jia J. Li; Alessandro Vasciaveo; Dimitris Karagiannis; Zhen Sun; Kristjan H. Gretarsson; Xiao Chen; Ouathek Ouerfelli; Fabio Socciarelli; Ziv Frankenstein; Hanyang Dong; Min Zou; Wei Yuan; Guangli Yang; Gabriel M. Aizenman; Tania Pannellini; Xinjing Xu; Himisha Beltran; Yu Chen; Kevin Gardner; Brian D. Robinson; Johann de Bono; Or Gozani; Cory Abate-Shen; Mark A. Rubin; Massimo Loda; Charles L. Sawyers; Andrea Califano; Chao Lu; Michael M. Shen

ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L ERG驱动的前列腺癌起始具有细胞背景依赖性，并且需要KMT2A和DOT1L。

Nature Genetics

IF0

2025-08-26

OAAI

Weiran Feng; Erik Ladewig; Matthew Lange; Nazifa Salsabeel; Huiyong Zhao; Young Sun Lee; Anuradha Gopalan; Hanzhi Luo; Wenfei Kang; Ning Fan; Eric Rosiek; Elisa de Stanchina; Yu Chen; Brett S. Carver; Christina S. Leslie; Charles L. Sawyers

Reprogramming of human urine cells into cardiomyocytes via a small molecule cocktail in xeno-free conditions 在无异种条件下通过小分子鸡尾酒将人尿液细胞重编程为心肌细胞

Communications Medicine

IF6.3

2025-07-01

OAAI

Yu Chen; Aoli Li; Aijie Liu; Wei Zheng; Haishi Fan; Jingwei Zhang; Chenwen Huang

Disruption of TAD hierarchy promotes LTR co-option in cancer TAD层次结构的破坏促进了癌症的LTR选择

Nature Genetics

IF0

2025-06-30

OAAI

Elissa W. P. Wong; Merve Sahin; Rui Yang; UkJin Lee; Dan Li; Yingqian A. Zhan; Rohan Misra; Fanny Tomas; Nawaf Alomran; Alexander Polyzos; Cindy J. Lee; Tuan Trieu; Alexander Martinez-Fundichely; Thomas Wiesner; Andrew Rosowicz; Shuyuan Cheng; Christina Liu; Morgan Lallo; Alexander N. Shoushtari; Taha Merghoub; Pierre-Jacques Hamard; Richard Koche; Ekta Khurana; Effie Apostolou; Deyou Zheng; Yu Chen; Christina S. Leslie; Ping Chi

A multi-omics analysis reveals candidate genes for Cd tolerance in Paspalum vaginatum

BMC PLANT BIOLOGY

IF4.8

2025-04-08

OAAI

Hu, Xu; Pan, Ling; Fu, Chunchan; Zhu, Qing; Hao, Jiangshan; Wang, Xiaochun; Nawaz, Mohsin; Qu, Jia; Zhang, Jinlin; Chen, Yu; Zong, Junqin; Liao, Li; Tang, Minqiang; Wang, Zhiyong

Identification of GDP as a small inhibitory molecule in HepG2 cells by non-targeted metabolomics analysis 通过非靶向代谢组学分析鉴定GDP为HepG2细胞中的小分子抑制剂

ONCOLOGY LETTERS

IF2.2

2025-02-11

OAAI

Peng, Zhilin; Xu, Siting; Wang, Haocheng; Huang, Yanli; Liu, Siyuan; Jiao, Zhongbei; Lin, Mei; Zhu, Ping; Chen, Yu; Shi, Yan; Wang, Yuequn; Li, Yongqing; Yuan, Wuzhou; Wu, Xiushan; Jiang, Zhigang; Li, Fang; Fan, Xiongwei

Spatial proximity of CD8+ T cells to tumor cells predicts neoadjuvant therapy efficacy in breast cancer

NPJ BREAST CANCER

IF7.6

2025-02-10

OAAI

Liang, Hongling; Huang, Jianqing; Li, Hongsheng; He, Weixing; Ao, Xiang; Xie, Zhi; Chen, Yu; Lv, Zhiyi; Zhang, Leyao; Zhong, Yanhua; Tan, Xiaojun; Han, Guodong; Zhou, Jie; Qiu, Ni; Jiang, Ming; Xia, Haoming; Zhan, Yongtao; Jiao, Lei; Ma, Jie; Radisky, Derek; Huang, Jia; Zhang, Xuchao

A genome-wide CRISPR activation screen to identify beta glucocerebrosidase modifiers

MOLECULAR GENETICS AND METABOLISM

IF3.5

2025-02-01

PREAI

Rytel, Krystyna N.; Chen, Yu; Yin, Jiang; Aguzzi, Adriano; Sidransky, Ellen

β-Hydroxybutyrate Alleviates Atherosclerotic Calcification by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis via AMPK/Nrf2 Pathway β-羟基丁酸通过抑制内质网应激介导的凋亡，经由AMPK/Nrf2通路减轻动脉粥样硬化钙化。

NUTRIENTS

IF5

2024-12-30

OAAI

Chen, Yu; You, Yiran; Wang, Xin; Jin, Yufeng; Zeng, Yupeng; Pan, Zhijun; Li, Dan; Ling, Wenhua

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation (vol 13,6951 ,2022)

NATURE COMMUNICATIONS

IF15.7

2024-12-10

OAAI

Shi, Chengyu; Wang, Ying; Wu, Minjie; Chen, Yu; Liu, Fangzhou; Shen, Zheyuan; Wang, Yiran; Xie, Shaofang; Shen, Yingying; Sang, Lingjie; Zhang, Zhen; Gao, Zerui; Yang, Luojia; Qu, Lei; Yang, Zuozhen; He, Xinyu; Guo, Yu; Pan, Chenghao; Che, Jinxin; Ju, Huaiqiang; Liu, Jian; Cai, Zhijian; Yan, Qingfeng; Yu, Luyang; Wang, Liangjing; Dong, Xiaowu; Xu, Pinglong; Shao, Jianzhong; Liu, Yang; Li, Xu; Wang, Wenqi; Zhou, Ruhong; Zhou, Tianhua; Lin, Aifu

Rewiring of Uric Acid Metabolism in the Intestine Promotes High-Altitude Hypoxia Adaptation in Humans 肠道中尿酸代谢的重新布线促进了人类的高原缺氧适应

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2024-11-04

OAAI

Su, Qian; Li, Yu-Chun; Zhuang, Dao-Hua; Liu, Xin-Yuan; Gao, Han; Li, Dong; Chen, Yu; Ge, Ming-Xia; Han, Yi-Ming; Gao, Zong-Liang; Yin, Fan-Qian; Zhao, Long; Zhang, Yun-Xia; Yang, Li-Qin; Zhao, Qin; Luo, Yong-Jun; Zhang, Zhigang; Kong, Qing-Peng

Development and validation of a simulation training platform for the ligation of deep dorsal vein complex in radical prostatectomy

FRONTIERS IN ONCOLOGY

IF3.3

2024-10-04

OAAI

Chen, Yu; Tan, Qi; Zhu, Jingzhen; Zhou, Luqiang; Li, Siyue; Zheng, Ji

The role of signaling pathways mediated by the GPCRs CysLTR1/2 in melanocyte proliferation and senescence

SCIENCE SIGNALING

IF6.6

2024-09-17

PREAI

Huber, Thomas; Horioka-Duplix, Mizuho; Chen, Yuanhuang; Saca, Victoria R.; Ceraudo, Emilie; Chen, Yu; Sakmar, Thomas P.

Gut microbiota contributes to high-altitude hypoxia acclimatization of human populations

GENOME BIOLOGY

IF9.4

2024-08-28

OAAI

Su, Qian; Zhuang, Dao-Hua; Li, Yu-Chun; Chen, Yu; Wang, Xia-Yan; Ge, Ming-Xia; Xue, Ting-Yue; Zhang, Qi-Yuan; Liu, Xin-Yuan; Yin, Fan-Qian; Han, Yi-Ming; Gao, Zong-Liang; Zhao, Long; Li, Yong-Xuan; Lv, Meng-Jiao; Yang, Li-Qin; Xia, Tian-Rui; Luo, Yong-Jun; Zhang, Zhigang; Kong, Qing-Peng

[Corrigendum] Omi/HtrA2 pro-apoptotic marker differs in various hepatocellular carcinoma cell lines owing to ped/pea-15 expression level

ONCOLOGY REPORTS

IF3.9

2024-08-28

OAAI

Xu, Zongquan; Chen, Yu; Xu, Guohui; Peng, Cheng; Liu, Enyu; Li, Yunguang; Niu, Jun; Li, Changhai

scRNA-seq reveals the landscape of immune repertoire of PBMNCs in iMCD

ONCOGENE

IF7.3

2024-08-15

PREAI

Yin, Xuejiao; Liu, Yi; Lv, Zuopo; Ding, Shengnan; Ma, Liya; Yang, Min; Yao, Meiqiu; Zhu, Li; Zhao, Shuqi; Chen, Yu; Ge, Jiaying; Tong, Hongyan; Meng, Haitao; You, Liangshun

Assessment of HER2 status in extramammary Paget disease and its implication for disitamab vedotin, a novel humanized anti-HER2 antibody-drug conjugate therapy

FRONTIERS OF MEDICINE

IF3.5

2024-05-14

PREAI

Jia, Jia; Mao, Lili; Lin, Jing; Li, Wenyu; Yuan, Pei; Guo, Lei; Dai, Jie; Li, Caili; Bai, Xue; Li, Zhongwu; Chen, Yu; Guo, Jun; Ying, Jianming; Si, Lu

ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

CANCER DISCOVERY

IF33.3

2024-04-08

OAAI

Xu, Yaru; Yang, Yuqiu; Wang, Zhaoning; Sjoestroem, Martin; Jiang, Yuyin; Tang, Yitao; Cheng, Siyuan; Deng, Su; Wang, Choushi; Gonzalez, Julisa; Johnson, Nickolas A.; Li, Xiang; Li, Xiaoling; Metang, Lauren A.; Mukherji, Atreyi; Xu, Quanhui; Tirado, Carla R.; Wainwright, Garrett; Yu, Xinzhe; Barnes, Spencer; Hofstad, Mia; Chen, Yu; Zhu, Hong; Hanker, Ariella B.; Raj, Ganesh V.; Zhu, Guanghui; He, Housheng H.; Wang, Zhao; Arteaga, Carlos L.; Liang, Han; Feng, Felix Y.; Wang, Yunguan; Wang, Tao; Mu, Ping

研究方向