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Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion see Oh, Chang Joo; Kim, Min-Ji; Lee, Ji-Min; Kim, Dong Hun; Kim, Il-Young; Park, Sanghee; Kim, Yeongmin; Lee, Kyung-Bok; Lee, Sang-Hee; Lim, Chae Won; Kim, Myeongjin; Lee, Jung -Yi; Pagire, Haushabhau S.; Pagire, Suvarna H.; Bae, Myung Ae; Chanda, Dipanjan; Thoudam, Themis; Khang, Ah Reum; Harris, Robert A.; Ahn, Jin Hee; Jeon, Jae-Han; Lee, In-Kyu 分享 收藏
Enhancement of the SESN2-SHP cascade by melatonin ameliorates hepatic gluconeogenesis by inhibiting the CRBN-BTG2-CREBH signaling pathway An, Seungwon; Nedumaran, Balachandar; Koh, Hong; Joo, Dong Jin; Lee, Hyungjo; Park, Chul-Seung; Harris, Robert A.; Shin, Keong Sub; Djalilian, Ali R.; Kim, Yong Deuk 分享 收藏
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Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcoholassociated liver disease Thoudam, Themis; Chanda, Dipanjan; Lee, Jung Yi; Jung, Min-Kyo; Sinam, Ibotombi Singh; Kim, Byung-Gyu; Park, Bo-Yoon; Kwon, Woong Hee; Kim, Hyo-Jeong; Kim, Myeongjin; Lim, Chae Won; Lee, Hoyul; Huh, Yang Hoon; Miller, Caroline A.; Saxena, Romil; Skill, Nicholas J.; Huda, Nazmul; Kusumanchi, Praveen; Ma, Jing; Yang, Zhihong; Kim, Min-Ji; Mun, Ji Young; Harris, Robert A.; Jeon, Jae-Han; Liangpunsakul, Suthat; Lee, In-Kyu 分享 收藏
Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation 抑制CD4 T细胞丙酮酸脱氢酶激酶4减轻肠道炎症 Lee, Hoyul; Han, Jae; Lee, Yu-Jeong; Kim, Mi-Jin; Kwon, Woong Hee; Chanda, Dipanjan; Thoudam, Themis; Pagire, Haushabhau S.; Pagire, Suvarna H.; Ahn, Jin Hee; Harris, Robert A.; Kim, Eun Soo; Lee, In-Kyu 分享 收藏
Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status Thoudam, Themis; Chanda, Dipanjan; Sinam, Ibotombi Singh; Kim, Byung-Gyu; Kim, Mi-Jin; Oh, Chang Joo; Lee, Jung Yi; Kim, Min-Ji; Park, Soo Yeun; Lee, Shin Yup; Jung, Min-Kyo; Mun, Ji Young; Harris, Robert A.; Ishihara, Naotada; Jeon, Jae-Han; Lee, In-Kyu 分享 收藏
Pyruvate dehydrogenase kinase 1 and 2 deficiency reduces high-fat diet-induced hypertrophic obesity and inhibits the differentiation of preadipocytes into mature adipocytes Kang, Hyeon-Ji; Min, Byong-Keol; Choi, Won-Il; Jeon, Jae-Han; Kim, Dong Wook; Park, Sungmi; Lee, Yun-Kyung; Kim, Hwa-jin; Byeon, Ju-Eun; Go, Younghoon; Ham, Hye Jin; Jeon, Yong Hyun; Kim, Mi-Jin; Lee, Jung Yi; Wende, Adam R.; Choi, Sung Hee; Harris, Robert A.; Lee, In-Kyu 分享 收藏
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Safety and target engagement profile of two oxaloacetate doses in Alzheimer's patients Vidoni, Eric D.; Choi, In-Young; Lee, Phil; Reed, Gregory; Zhang, Na; Pleen, Joseph; Mahnken, Jonathan D.; Clutton, Jonathan; Becker, Annette; Sherry, Erica; Bothwell, Rebecca; Anderson, Heidi; Harris, Robert A.; Brooks, William; Wilkins, Heather M.; Mosconi, Lisa; Burns, Jeffrey M.; Swerdlow, Russell H. 分享 收藏
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SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα Naiman, Shoshana; Huynh, Frank K.; Gil, Reuven; Glick, Yair; Shahar, Yael; Touitou, Noga; Nahum, Liat; Avivi, Matan Y.; Roichman, Asael; Kanfi, Yariv; Gertler, Asaf A.; Doniger, Tirza; Ilkayeva, Olga R.; Abramovich, Ifat; Yaron, Orly; Lerrer, Batia; Gottlieb, Eyal; Harris, Robert A.; Gerber, Doron; Hirschey, Matthew D.; Cohen, Haim Y. 分享 收藏
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Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype 丙酮酸脱氢酶激酶是巨噬细胞向M1表型极化的代谢检查点 Min, Byong-Keol; Park, Sungmi; Kang, Hyeon-Ji; Kim, Dong Wook; Ham, Hye Jin; Ha, Chae-Myeong; Choi, Byung-Jun; Lee, Jung Yi; Oh, Chang Joo; Yoo, Eun Kyung; Kim, Hui Eon; Kim, Byung-Gyu; Jeon, Jae-Han; Hyeon, Do Young; Hwang, Daehee; Kim, Yong-Hoon; Lee, Chul-Ho; Lee, Taeho; Kim, Jung-whan; Choi, Yeon-Kyung; Park, Keun-Gyu; Chawla, Ajay; Lee, Jongsoon; Harris, Robert A.; Lee, In-Kyu 分享 收藏
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PDK4 Augments ER-Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity Thoudam, Themis; Ha, Chae-Myeong; Leem, Jaechan; Chanda, Dipanjan; Park, Jong-Seok; Kim, Hyo-Jeong; Jeon, Jae-Han; Choi, Yeon-Kyung; Liangpunsakul, Suthat; Huh, Yang Hoon; Kwon, Tae-Hwan; Park, Keun-Gyu; Harris, Robert A.; Park, Kyu-Sang; Rhee, Hyun-Woo; Lee, In-Kyu 分享 收藏
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PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels Park, Bo-Yoon; Jeon, Jae-Han; Go, Younghoon; Ham, Hye Jin; Kim, Jeong-Eun; Yoo, Eun Kyung; Kwon, Woong Hee; Jeoung, Nam-Ho; Jeon, Yong Hyun; Koo, Seung-Hoi; Kim, Byung-Gyu; He, Ling; Park, Keun-Gyu; Harris, Robert A.; Lee, In-Kyu 分享 收藏
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