Robert S. Haltiwanger - Publications, H-index & Citations

Robert S. Haltiwanger

university system of georgia

66H指数

222论文数

1.4W被引数

收录论文 110

发表时间

Crystal structure of a β1,3-Glucosyltransferase reveals an unusual substrate recognition by a two-domain GT-A fold glycosyltransferase β1,3-葡糖基转移酶的晶体结构揭示了一种由双结构域GT-A折叠糖基转移酶介导的异常底物识别

Journal of Biological Chemistry

IF3.9

2026-09-01

PREAI

Berardinelli, Steven J.; Kadirvelraj, Renuka; Luther, Kelvin B.; Gao, Zhongwei; Chapla, Digantkumar; Huang, Chin; Tehrani, Daniel M.; Zhang, Ao; Moremen, Kelley W.; Wood, Zachary A.; Haltiwanger, Robert S.

POGLUT2 and POGLUT3: Two essential protein O-glucosyltransferases modifying EGF repeats in extracellular matrix proteins POGLUT2和POGLUT3：两种修饰细胞外基质蛋白表皮生长因子重复序列的必需蛋白O-葡萄糖基转移酶

Biochimica et Biophysica Acta (BBA) - General Subjects

IF0

2026-04-08

OAAI

Nicholas R. Kegley; Bernadette C. Holdener; Robert S. Haltiwanger

Loss of POGLUT2/3-mediated O-glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants POGLUT2/3介导的O-葡萄糖基化缺失产生类似Fibrillin1突变体的肺和主动脉表型

Developmental Dynamics

IF1.5

2026-01-01

OAAI

Neupane, Sanjiv; Almiroudis, Angelina; Donnelly, Kaitlyn E.; Haltiwanger, Robert S.; Holdener, Bernadette C.

POGLUT2/3 mediated EGF O-glucosylation promotes separation of digits 2 and 3 by influencing fibrillin network reorganization, signaling, and cell dynamics POGLUT2/3介导的EGF O-葡萄糖基化通过影响成纤维细胞生长因子网络重组、信号传导和细胞动力学，促进第2和第3指（趾）的分离。

Developmental Biology

IF2.1

2025-08-08

OAAI

Sanjiv Neupane; Isabella A. Janowicz; Alan R.F. Godwin; Kaitlyn E. Donnelly; Richard C. Grady; Robert S. Haltiwanger; Clair Baldock; Bernadette C. Holdener

Impact of N-linked glycans on the dual short fibulin/LTBP-4 axes regulating elastogenesis N-连接糖基化对调节弹性蛋白生成的双短纤维蛋白/LTBP-4轴的影响

febs journal

IF0

2025-07-03

OAAI

Valentin Nelea; Heena Kumra; Chae Syng Lee; Daniel Williamson; Hana Hakami; Rong-Mo Zhang; Neha E. H. Dinesh; Robert Haltiwanger; Dieter P. Reinhardt

Protein O-Fucosyltransferases: Biological Functions and Molecular Mechanisms in Mammals

MOLECULES

IF4.6

2025-03-26

OAAI

Hao, Huilin; Eberand, Benjamin M.; Larance, Mark; Haltiwanger, Robert S.

Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants

MSPHERE

IF3.1

2025-02-25

OAAI

Tiwari, Megna; Gas-Pascual, Elisabet; Goyal, Manish; Popov, Marla; Matsumoto, Kenjiroo; Grafe, Marianne; Graef, Ralph; Haltiwanger, Robert S.; Olszewski, Neil; Orlando, Ron; Samuelson, John C.; West, Christopher M.

Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development

GLYCOBIOLOGY

IF3.3

2024-07-08

PREAI

Matsumoto, Kenjiroo; Luther, Kelvin B.; Haltiwanger, Robert S.

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fi brillin in lung tissues

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-07-01

OAAI

Neupane, Sanjiv; Williamson, Daniel B.; Roth, Robyn A.; Halabi, Carmen M.; Haltiwanger, Robert S.; Holdener, Bernadette C.

Analysis of the Healthy Platelet Proteome Identifies a New Form of Domain-Specific OFucosylation

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2024-02-01

OAAI

Houlahan, Callum B.; Kong, Yvonne; Johnston, Bede; Cielesh, Michelle; Chau, The Huong; Fenwick, Jemma; Coleman, Paul R.; Hao, Huilin; Haltiwanger, Robert S.; Thaysen-Andersen, Morten; Passam, Freda H.; Larance, Mark

In vivo evidence for GDP-fucose transport in the absence of transporter SLC35C1 and putative transporter SLC35C2

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-12-01

OAAI

Lu, Linchao; Varshney, Shweta; Yuan, Youxi; Wei, Hua-Xing; Tanwar, Ankit; Sundaram, Subha; Nauman, Mohd; Haltiwanger, Robert S.; Stanley, Pamela

Disease modeling and gene correction of LGMDR21 iPSCs elucidates the role of POGLUT1 in skeletal muscle maintenance, regeneration, and the satellite cell niche

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2023-09-01

OAAI

Ortiz-Vitali, Jose L.; Wu, Jianbo; Xu, Nasa; Shieh, Annie W.; Niknejad, Nima; Takeuchi, Megumi; Paradas, Carmen; Lin, Chunru; Jafar-Nejad, Hamed; Haltiwanger, Robert S.; Wang, Sidney H.; Darabi, Radbod

Two NOTCH1 O-fucose sites have opposing functions in mouse retinal angiogenesis

GLYCOBIOLOGY

IF3.3

2023-06-17

PREAI

LoPilato, Rachel K.; Kroeger, Heike; Mohan, Sneha K.; Lauderdale, James D.; Grimsey, Neil; Haltiwanger, Robert S.

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway Cripto作为配体和辅助受体在nodal信号通路中的双重作用

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

205

OAAI

Yan, YT; Liu, JJ; Luo, Y; Chaosu, E; Haltiwanger, RS; Abate-Shen, C; Shen, MM

O-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules

GLYCOBIOLOGY

IF3.3

2023-01-31

OAAI

Berardinelli, Steven J.; Sillato, Andrew R.; Grady, Richard C.; Neupane, Sanjiv; Ito, Atsuko; Haltiwanger, Robert S.; Holdener, Bernadette C.

Fucosylation of HLA-DRB1 regulates CD4+ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy

NATURE CANCER

IF28.5

2023-01-23

OAAI

Lester, Daniel K.; Burton, Chase; Gardner, Alycia; Innamarato, Patrick; Kodumudi, Krithika; Liu, Qian; Adhikari, Emma; Ming, Qianqian; Williamson, Daniel B.; Frederick, Dennie T.; Sharova, Tatyana; White, Michael G.; Markowitz, Joseph; Cao, Biwei; Nguyen, Jonathan; Johnson, Joseph; Beatty, Matthew; Mockabee-Macias, Andrea; Mercurio, Matthew; Watson, Gregory; Chen, Pei-Ling; McCarthy, Susan; MoranSegura, Carlos; Messina, Jane; Thomas, Kerry L.; Darville, Lancia; Izumi, Victoria; Koomen, John M.; Pilon-Thomas, Shari A.; Ruffell, Brian; Luca, Vincent C.; Haltiwanger, Robert S.; Wang, Xuefeng; Wargo, Jennifer A.; Boland, Genevieve M.; Lau, Eric K.

Cancer-associated Notch receptor variants lead to O-fucosylation defects that deregulate Notch signaling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-12-01

OAAI

Pennarubia, Florian; Ito, Atsuko; Takeuchi, Megumi; Haltiwanger, Robert S.

Origin of cytoplasmic GDP-fucose determines its contribution to glycosylation reactions

JOURNAL OF CELL BIOLOGY

IF6.4

2022-09-02

OAAI

Sosicka, Paulina; Ng, Bobby G.; Pepi, Lauren E.; Shajahan, Asif; Wong, Maurice; Scott, David A.; Matsumoto, Kenjiroo; Xia, Zhi-Jie; Lebrilla, Carlito B.; Haltiwanger, Robert S.; Azadi, Parastoo; Freeze, Hudson H.

Fringe GlcNAc-transferases differentially extend O-fucose on endogenous NOTCH1 in mouse activated T cells 边缘GlcNAc转移酶在小鼠活化T细胞中内源性NOTCH1上差异延伸O-岩藻糖

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-07-01

OAAI

Matsumoto, Kenjiroo; Kumar, Vivek; Varshney, Shweta; V. Nairn, Alison; Ito, Atsuko; Pennarubia, Florian; Moremen, Kelley W.; Stanley, Pamela; Haltiwanger, Robert S.

O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-06-01

OAAI

Berardinelli, Steven J.; Eletsky, Alexander; Valero-Gonzalez, Jessika; Ito, Atsuko; Manjunath, Rajashri; Hurtado-Guerrero, Ramon; Prestegard, James H.; Woods, Robert J.; Haltiwanger, Robert S.

研究方向