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Pulmonary delivery of clofoctol-loaded nanoparticles inhibits SARS-CoV-2 replication and reduces pneumonia 氯富克多尔负载纳米粒的肺递送抑制SARS-CoV-2复制并减轻肺炎 Bourguignon, Tom; Godinez-Leon, Jesus Alfredo; Pochet, Amine; Shamsuddin, Tahmida; Sencio, Valentin; Chatagnon, Jonathan; Grande, Axelle; Fine, Joan; Heumel, Severine; Robil, Cyril; Delval, Lou; Piveteau, Catherine; Belouzard, Sandrine; Brodin, Priscille; Trottein, Francois; Machelart, Arnaud; Gref, Ruxandra 分享 收藏
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Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice 肺泡巨噬细胞中Rev-erb-α的拮抗作用可保护老年小鼠免受肺炎链球菌感染 Angulo, Fabiola Silva; Joseph, Claudine Vanessa; Delval, Lou; Deruyter, Lucie; Heumel, Severine; Bicharel, Marie; Rodrigues, Patricia Brito; Sencio, Valentin; Bourguignon, Tom; Machado, Marina Gomes; Fourcot, Marie; Delhaye, Stephane; Salome-Desnoulez, Sophie; Valet, Philippe; Adnot, Serge; Wolowczuk, Isabelle; Sirard, Jean-Claude; Pichavant, Muriel; Staels, Bart; Haas, Joel T.; Gref, Ruxandra; Vandel, Jimmy; Machelart, Arnaud; Duez, Helene; Pourcet, Benoit; Trottein, Francois 分享 收藏
IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections Ifn-γ 使骨髓中性粒细胞在严重病毒性呼吸道感染中获得调节功能 Creusat, Florent; Jouan, Youenn; Gonzalez, Loic; Barsac, Emilie; Ilango, Guy; Lemoine, Roxane; Soulard, Daphnee; Hankard, Antoine; Boisseau, Chloe; Guillon, Antoine; Lin, Qiaochu; Herbozo, Carolina de Amat; Sencio, Valentin; Winter, Nathalie; Sizaret, Damien; Trottein, Francois; Si-Tahar, Mustapha; Briard, Benoit; Mallevaey, Thierry; Faveeuw, Christelle; Baranek, Thomas; Paget, Christophe 分享 收藏
Hyperforin, the major metabolite of St. John's wort, exhibits pan-coronavirus antiviral activity Raczkiewicz, Imelda; Riviere, Celine; Bouquet, Peggy; Desmarets, Lowiese; Tarricone, Audrey; Camuzet, Charline; Francois, Nathan; Lefevre, Gabriel; Angulo, Fabiola Silva; Robil, Cyril; Trottein, Francois; Sahpaz, Sevser; Dubuisson, Jean; Belouzard, Sandrine; Goffard, Anne; Seron, Karin 分享 收藏
Faecalibacterium duncaniae as a novel next generation probiotic against influenza Chollet, Loic; Heumel, Severine; Deruyter, Lucie; Bouilloux, Fabrice; Delval, Lou; Robert, Veronique; Gevaert, Marie-Helene; Pichavant, Muriel; Sencio, Valentin; Robil, Cyril; Wolowczuk, Isabelle; Sokol, Harry; Auger, Sandrine; Douablin, Alexandre; Langella, Philippe; Chatel, Jean-Marc; Grangette, Corinne; Trottein, Francois 分享 收藏
Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid as a protective gut microbial metabolite against influenza infection Shot弹枪宏基因组学和系统靶向代谢组学强调indole-3-propionic酸是一种保护性肠道微生物代谢产物，可抵抗流感感染 Heumel, Severine; Rodovalho, Vinicius de Rezende; Urien, Charlotte; Specque, Florian; Rodrigues, Patricia Brito; Robil, Cyril; Delval, Lou; Sencio, Valentin; Descat, Amandine; Deruyter, Lucie; Ferreira, Stephanie; Machado, Marina Gomes; Barthelemy, Adeline; Angulo, Fabiola Silva; Haas, Joel. T.; Goosens, Jean Francois; Wolowczuk, Isabelle; Grangette, Corinne; Rouille, Yves; Grimaud, Ghjuvan; Lenski, Marie; Hennart, Benjamin; Vinolo, Marco Aurelio Ramirez; Trottein, Francois 分享 收藏
Role of astrocyte senescence regulated by the non- canonical autophagy in the neuroinflammation associated to cerebral malaria Hellani, Fatima; Leleu, Ines; Saidi, Nasreddine; Martin, Nathalie; Lecoeur, Cecile; Werkmeister, Elisabeth; Koffi, David; Trottein, Francois; Yapo-Ette, Helene; Das, Bidyut; Abbadie, Corinne; Pied, Sylviane 分享 收藏
Depletion of preexisting B-cell lymphoma 2-expressing senescent cells before vaccination impacts antigen-specific antitumor immune responses in old mice 疫苗接种前已存在的b细胞淋巴瘤2表达衰老细胞的耗竭会影响老年小鼠的抗原特异性抗肿瘤免疫反应 Cobanoglu, Ozmen; Delval, Lou; Ferrari, Daniele; Deruyter, Lucie; Heumel, Severine; Wolowczuk, Isabelle; Hussein, Abir; Menevse, Ayse Nur; Bernard, David; Beckhove, Philip; Alves, Frauke; Trottein, Francois 分享 收藏
Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death 男性长COVID认知障碍和生殖激素缺乏可能源于GnRH神经元死亡 Sauve, Florent; Nampoothiri, Sreekala; Clarke, Sophie A.; Fernandois, Daniela; Coelho, Caio Fernando Ferreira; Dewisme, Julie; Mills, Edouard G.; Ternier, Gaetan; Cotellessa, Ludovica; Iglesias-Garcia, Cristina; Mueller-Fielitz, Helge; Lebouvier, Thibaud; Perbet, Romain; Florent, Vincent; Baroncini, Marc; Sharif, Ariane; Ereno-Orbea, June; Mercado-Gomez, Maria; Palazon, Asis; Mattot, Virginie; Pasquier, Florence; Catteau-Jonard, Sophie; Martinez-Chantar, Maria; Hrabovszky, Erik; Jourdain, Merce; Deplanque, Dominique; Morelli, Annamaria; Guarnieri, Giulia; Storme, Laurent; Robil, Cyril; Trottein, Francois; Nogueiras, Ruben; Schwaninger, Markus; Pigny, Pascal; Poissy, Julien; Chachlaki, Konstantina; Maurage, Claude-Alain; Giacobini, Paolo; Dhillo, Waljit; Rasika, S.; Prevot, Vincent 分享 收藏
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Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters 去除衰老细胞可降低SARS-CoV-2-infected，老年仓鼠的病毒载量并减轻肺部和全身炎症 Delval, Lou; Hantute-Ghesquier, Aline; Sencio, Valentin; Flaman, Jean Michel; Robil, Cyril; Angulo, Fabiola Silva; Lipskaia, Larissa; cobanoglu, Ozmen; Lacoste, Anne-Sophie; Machelart, Arnaud; Danneels, Adeline; Corbin, Mathieu; Deruyter, Lucie; Heumel, Severine; Idziorek, Thierry; Seron, Karin; Sauve, Florent; Bongiovanni, Antonino; Prevot, Vincent; Wolowczuk, Isabelle; Belouzard, Sandrine; Saliou, Jean-Michel; Gosset, Philippe; Bernard, David; Rouille, Yves; Adnot, Serge; Duterque-Coquillaud, Martine; Trottein, Francois 分享 收藏
Characterization of Two Parabacteroides distasonis Candidate Strains as New Live Biotherapeutics against Obesity 表征两个副杆菌distasonis候选菌株作为抗肥胖的新型活生物疗法 Cuffaro, Bernardo; Boutillier, Denise; Desramaut, Jeremy; Jablaoui, Amin; Werkmeister, Elisabeth; Trottein, Francois; Waligora-Dupriet, Anne-Judith; Rhimi, Moez; Maguin, Emmanuelle; Grangette, Corinne 分享 收藏
Tirap controls Mycobacterium tuberculosis phagosomal acidification Tirap控制结核分枝杆菌吞噬体酸化 Belhaouane, Imene; Pochet, Amine; Chatagnon, Jonathan; Hoffmann, Eik; Queval, Christophe J. J.; Deboosere, Nathalie; Boidin-Wichlacz, Celine; Majlessi, Laleh; Sencio, Valentin; Heumel, Severine; Vandeputte, Alexandre; Werkmeister, Elisabeth; Fievez, Laurence; Bureau, Fabrice; Rouille, Yves; Trottein, Francois; Chamaillard, Mathias; Brodin, Priscille; Machelart, Arnaud 分享 收藏
SARS-CoV-2 infection induces persistent adipose tissue damage in aged golden Syrian hamsters Bogard, Gemma; Barthelemy, Johanna; Hantute-Ghesquier, Aline; Sencio, Valentin; Brito-Rodrigues, Patricia; Seron, Karin; Robil, Cyril; Flourens, Anne; Pinet, Florence; Eberle, Delphine; Trottein, Francois; Duterque-Coquillaud, Martine; Wolowczuk, Isabelle 分享 收藏
Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters Briand, Francois; Sencio, Valentin; Robil, Cyril; Heumel, Severine; Deruyter, Lucie; Machelart, Arnaud; Barthelemy, Johanna; Bogard, Gemma; Hoffmann, Eik; Infanti, Fabrice; Domenig, Oliver; Chabrat, Audrey; Richard, Virgile; Prevot, Vincent; Nogueiras, Ruben; Wolowczuk, Isabelle; Pinet, Florence; Sulpice, Thierry; Trottein, Francois 分享 收藏
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