Discovery of therapeutic promising natural products to target Kv1.3 channel, a transmembrane protein regulating immune disorders, through multidimensional virtual screening, molecular dynamics simulations and biological validation通过多维虚拟筛选、分子动力学模拟和生物学验证,发现靶向Kv1.3通道(一种调节免疫紊乱的跨膜蛋白)的治疗前景良好的天然产物。INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESIF8.52025-05-011PRE