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N

Nina Van Opdenbosch

VIB
H指数:20
被引数:4,057

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Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity

发现具有外周和体内中枢活性的强效且能穿透血脑屏障的双环NLRP3抑制剂

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-02-110
PRE
Mammoliti, Oscar; Carbajo, Rodrigo; Perez-Benito, Laura; Yu, Xiaodi; Prieri, Marion L. C.; Bontempi, Leonardo; Embrechts, Sofie; Paesmans, Ine; Bassi, Michela; Bhattacharya, Anindya; Canellas, Santiago; De Hoog, Saskia; Demin, Samuel; Gijsen, Harrie J. M.; Hache, Geerwin; Jacobs, Tom; Jerhaoui, Soufyan; Leenaerts, Joseph; Lutter, Ferdinand H.; Mahieu, Michel; Matico, Rosalie; Miller, Robyn; Oehlrich, Daniel; Perrier, Mathieu; Ryabchuk, Pavel; Schepens, Wim; Sharma, Sujata; Somers, Marijke; Suarez, Javier; Surkyn, Michel; Van Opdenbosch, Nina; Verhulst, Tinne; Bottelbergs, Astrid
Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome
EMBO MOLECULAR MEDICINE
IF8.3
2024-12-090
PRE
Matico, Rosalie; Grauwen, Karolien; Chauhan, Dhruv; Yu, Xiaodi; Abdiaj, Irini; Adhikary, Suraj; Adriaensen, Ine; Aranzazu, Garcia Molina; Alcazar, Jesus; Bassi, Michela; Brisse, Ellen; Canellas, Santiago; Chaudhuri, Shubhra; Delgado, Francisca; Dieguez-Vazquez, Alejandro; Du Jardin, Marc; Eastham, Victoria; Finley, Michael; Jacobs, Tom; Keustermans, Ken; Kuhn, Robert; Llaveria, Josep; Leenaerts, Jos; Linares, Maria Lourdes; Martin, Maria Luz; Martin-Perez, Rosa; Martinez, Carlos; Miller, Robyn; Munoz, Frances M.; Muratore, Michael E.; Nooyens, Amber; Perez-Benito, Laura; Perrier, Mathieu; Pietrak, Beth; Serre, Jef; Sharma, Sujata; Somers, Marijke; Suarez, Javier; Tresadern, Gary; Trabanco, Andres A.; van den Bulck, Dries; Van Gool, Michiel; Van Hauwermeiren, Filip; Varghese, Teena; Vega, Juan Antonio; Youssef, Sameh A.; Edwards, Matthew J.; Oehlrich, Daniel; Van Opdenbosch, Nina
Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax

炭疽芽孢杆菌诱导巨噬细胞NLRP3炎性体激活和caspase-8-mediated凋亡促进致死性炭疽

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-01-0717
OAAI
Van Hauwermeiren, Filip; Van Opdenbosch, Nina; Van Gorp, Hanne; de Vasconcelos, Nathalia; van Loo, Geert; Vandenabeele, Peter; Kanneganti, Thirumala-Devi; Lamkanfi, Mohamed
Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2016-11-22134
OAAI
Van Gorp, Hanne; Saavedra, Pedro H. V.; de Vasconcelos, Nathalia M.; Van Opdenbosch, Nina; Vande Walle, Lieselotte; Matusiak, Magdalena; Prencipe, Giusi; Insalaco, Antonella; Van Hauwermeiren, Filip; Demon, Dieter; Bogaert, Delfien J.; Dullaers, Melissa; De Baere, Elfride; Hochepied, Tino; Dehoorne, Joke; Vermaelen, Karim Y.; Haerynck, Filomeen; De Benedetti, Fabrizio; Lamkanfi, Mohamed

研究方向

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M
Mohamed Lamkanfi
H 指数:78论文数:153被引数:2.8万
H
Hanne Van Gorp
H 指数:24论文数:67被引数:3,289
F
Filip Van Hauwermeiren
H 指数:25论文数:42被引数:3,554
L
Lieselotte Vande Walle
H 指数:33论文数:93被引数:1.0万
T
Thirumala‐Devi Kanneganti
H 指数:138论文数:455被引数:7.6万
M
Magdalena Matusiak
H 指数:15论文数:69被引数:1,763
M
Mohamed Lamkanfi
H 指数:24论文数:39被引数:4,447
D
Daniel Oehlrich
H 指数:25论文数:65被引数:1,896
R
Rosalie Matico
H 指数:20论文数:48被引数:1,505
N
Nathalia M. de Vasconcelos
H 指数:3论文数:3被引数:614