Ijeoma F. Uchegbu - Publications & Citations

Ijeoma F. Uchegbu

University College London

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收录论文 47

发表时间

Albumin-based nanoparticles encapsulating SN-38 demonstrate superior antitumor efficacy compared to irinotecan 白蛋白基纳米粒包封SN-38显示出比伊立替康更强的抗肿瘤效果。

Drug Delivery

IF8.1

2025-08-17

OAAI

Guojun Xiong; Shengxi Li; Andreas G. Schätzlein; Ijeoma F. Uchegbu

Dose-dependent delivery of genes to the cerebral cortex via the nasal route

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2023-09-01

OAAI

Fatani, Abdulhamid S.; Petkova, Asya; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

The topical ocular delivery of rapamycin to posterior eye tissues and the suppression of retinal inflammatory disease

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2022-06-01

OAAI

Badr, Moutaz Y.; Halwani, Abdulrahman A.; Odunze, Uchechukwu; Eskandarpour, Malihe; Calder, Virginia L.; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2022-04-01

OAAI

Dimiou, Savvas; Lopes, Rui M.; Kubajewska, Ilona; Mellor, Ryan D.; Schlosser, Corinna S.; Shet, Manjunath S.; Huang, Hugh; Akcan, Ozgur; Whiteside, Garth T.; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

Down-regulation of GP130 signaling sensitizes bladder cancer to cisplatin by impairing Ku70 DNA repair signaling and promoting apoptosis

CELLULAR SIGNALLING

IF3.7

2021-05-01

OAAI

He, Shanshan; Li, Gang; Schatzlein, Andreas G.; Humphrey, Peter A.; Weiss, Robert M.; Uchegbu, Ijeoma F.; Martin, Darryl T.

A polymeric aqueous tacrolimus formulation for topical ocular delivery

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2021-04-01

OAAI

Badr, Moutaz Y.; Abdulrahman, Nurul S.; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

A Self-Assembling Lipidic Peptide and Selective Partial V2 Receptor Agonist Inhibits Urine Production

SCIENTIFIC REPORTS

IF3.9

2020-04-29

OAAI

Patel, Sunish; Volpe, Antonella Bavuso; Awwad, Sahar; Schaetzlein, Andreas G.; Haider, Shozeb; Liu, Boqian; Uchegbu, Ijeoma F.

Nose-to-Brain Delivery

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2019-09-01

166

OAAI

Wang, Zian; Xiong, Guojun; Tsang, Wai Chun; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

Limiting the level of tertiary amines on polyamines leads to biocompatible nucleic acid vectors

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2017-06-01

OAAI

Carlos, Margarida Isabel Simao; Zheng, Kai; Garrett, Natalie; Arifin, Natrah; Workman, David G.; Kubajewska, Ilona; Halwani, Abdulrahman A.; Moger, Julian; Zhang, Qi; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

Nose to brain delivery in rats: Effect of surface charge of rhodamine B labeled nanocarriers on brain subregion localization

COLLOIDS AND SURFACES B-BIOINTERFACES

IF5.6

2017-06-01

OAAI

Bonaccorso, A.; Musumeci, T.; Serapide, M. F.; Pellitteri, R.; Uchegbu, I. F.; Puglisi, G.

Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2016-11-01

OAAI

Soundararajan, Ramesh; Sasaki, Kenji; Godfrey, Lisa; Odunze, Uchechukwu; Fereira, Nancy; Schatzlein, Andreas; Uchegbu, Ijeoma

Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels - A Strategy for Brain Cancer Treatments

PHARMACEUTICAL RESEARCH

IF4.3

2016-02-22

OAAI

Fisusi, Funmilola A.; Siew, Adeline; Chooi, Kar Wai; Okubanjo, Omotunde; Garrett, Natalie; Lalatsa, Katerina; Serrano, Dolores; Summers, Ian; Moger, Julian; Stapleton, Paul; Satchi-Fainaro, Ronit; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

Chitosan amphiphile nanoparticles reduced the myelosuppressive effects of lomustine

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Fisusi, Funmilola Adesodun; Okubanjo, Omotunde; Chooi, Kar Wai; Schatzlein, Andreas G.; Uchegbu, Ijeoma F.

Oral administration of a nano-enabled form of Met-Enkephalin peptide controls pancreatic cancer growth

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Marimuthu, Preethi; Uchegbu, Ijeoma F.; Schaetzlein, Andreas G.

Physical Characterisation and Long-Term Stability Studies on Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ)-A New Drug Delivery Polymer

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2014-08-01

PREAI

Chooi, Kar Wai; Carlos, Margarida Isabel Simao; Soundararajan, Ramesh; Gaisford, Simon; Arifin, Natrah; Schaetzlein, Andreas G.; Uchegbu, Ijeoma F.

Lomustine nanoparticles are effective brain cancer treatments.

CANCER RESEARCH

IF16.6

2013-04-01

PREAI

Fisusi, Funmilola A.; Alzharani, Ahmed; Summers, Ian; Morger, Julian; Okubanjo, Omotunde; Chooi, Kar Wai; Schaetzlein, Andreas G.; Uchegbu, Ijeoma F.

Nanomedicines and nanodiagnostics come of age

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2013-02-01

PREAI

Uchegbu, Ijeoma F.; Siew, Adeline

Nanofiber-Based Delivery of Therapeutic Peptides to the Brain 基于纳米纤维的治疗肽向大脑的递送

ACS NANO

IF16

2013-01-10

PREAI

Mazza, Mariarosa; Notman, Rebecca; Anwar, Jamshed; Rodger, Alison; Hicks, Matthew; Parkinson, Gary; McCarthy, Dave; Daviter, Tina; Moger, Julian; Garrett, Natalie; Mead, Tania; Briggs, Michael; Schaetzlein, Andreas G.; Uchegbu, Ijeoma F.

Polyamine Aza-Cyclic Compounds Demonstrate Anti-Proliferative Activity In Vitro But Fail to Control Tumour Growth In Vivo

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2010-11-01

PREAI

Wong, Pui Ee; Tetley, Laurence; Dufes, Christine; Chooi, Kar Wai; Bolton, Katherine; Schaetzlein, Andreas G.; Uchegbu, Ijeoma F.

In silico modelling of drug-polymer interactions for pharmaceutical formulations

JOURNAL OF THE ROYAL SOCIETY INTERFACE

IF3.5

2010-06-02

OAAI

Ahmad, Samina; Johnston, Blair F.; Mackay, Simon P.; Schatzlein, Andreas G.; Gellert, Paul; Sengupta, Durba; Uchegbu, Ijeoma F.

研究方向