未登录
分享
收藏
分享
收藏Enterovirus 71 inhibits cellular type I interferon signaling by inhibiting host RIG-I ubiquitination肠病毒71通过抑制宿主rig-i泛素化抑制细胞I型干扰素信号传导
Chen, Ning; Li, Xingzhi; Li, Pengfei; Pan, Ziye; Ding, Yun; Zou, Dehua; Zheng, Liang; Zhang, Yating; Li, Liyang; Xiao, Lijie; Song, Baifen; Cui, Yudong; Cao, Hongwei; Zhang, Hua
分享
收藏
分享
收藏
分享
收藏Effective asymmetric bioreduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate by recombinant E. coli CCZU-A13 in [Bmim]PF6-hydrolyzate media在 [Bmim]PF6-hydrolyzate培养基中通过重组大肠杆菌CCZU-A13将4-氯-3-氧代丁酸乙酯有效不对称生物还原为 (R)-4-氯-3-羟基丁酸乙酯
He, Yu-Cai; Tao, Zhi-Cheng; Di, Jun-Hua; Chen, Liang; Zhang, Lin-Bing; Zhang, Dan-Ping; Chong, Gang-Gang; Liu, Feng; Ding, Yun; Jiang, Chun-Xia; Ma, Cui-Luan
分享
收藏The nuclear protein Sam68 is recruited to the cytoplasmic stress granules during enterovirus 71 infection
Zhang, Hua; Chen, Ning; Li, Pengfei; Pan, Ziye; Ding, Yun; Zou, Dehua; Li, Liyang; Xiao, Lijie; Shen, Binglei; Liu, Shuxia; Cao, Hongwei; Cui, Yudong
分享
收藏Effective pretreatment of sugarcane bagasse with combination pretreatment and its hydrolyzates as reaction media for the biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by whole cells of E-coli CCZU-K14通过组合预处理及其水解产物对甘蔗渣进行有效预处理,作为大肠杆菌CCZU-K14全细胞生物合成 (S)-4-氯-3-羟基丁酸乙酯的反应介质
He, Yu-Cai; Zhang, Dan-Ping; Di, Jun-Hua; Wu, Yin-Qi; Tao, Zhi-Cheng; Liu, Feng; Zhang, Zhi-Jun; Chong, Gang-Gang; Ding, Yun; Ma, Cui-Luan
分享
收藏
分享
收藏Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors
Deng, Hongfeng; Zhou, Jingye; Sundersingh, Flora; Messer, Jeffrey A.; Somers, Donald O.; Ajakane, Myriam; Arico-Muendel, Christopher C.; Beljean, Arthur; Belyanskaya, Svetlana L.; Bingham, Ryan; Blazensky, Emily; Boullay, Anne-Benedicte; Boursier, Eric; Chai, Jing; Carter, Paul; Chung, Chun-Wa; Daugan, Alain; Ding, Yun; Herry, Kenny; Hobbs, Clare; Humphries, Eric; Kollmann, Christopher; Van Loc Nguyen; Nicodeme, Edwige; Smith, Sarah E.; Dodic, Nerina; Ancellin, Nicolas
分享
收藏The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors
Wood, Edgar R.; Bledsoe, Randy; Chai, Jing; Daka, Philias; Deng, Hongfeng; Ding, Yun; Harris-Gurley, Sarah; Kryn, Luz Helena; Nartey, Eldridge; Nichols, James; Nolte, Robert T.; Prabhu, Ninad; Rise, Cecil; Sheahan, Timothy; Shotwell, J. Brad; Smith, Danielle; Tai, Vince; Taylor, J. David; Tomberlin, Ginger; Wang, Liping; Wisely, Bruce; You, Shihyun; Xia, Bing; Dickson, Hamilton
分享
收藏Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library
Deng, Hongfeng; Zhou, Jingye; Sundersingh, Flora S.; Summerfield, Jennifer; Somers, Don; Messer, Jeffrey A.; Satz, Alexander L.; Ancellin, Nicolas; Arico-Muendel, Christopher C.; Bedard, Katie L. (Sargent); Beljean, Arthur; Belyanskaya, Svetlana L.; Bingham, Ryan; Smith, Sarah E.; Boursier, Eric; Carter, Paul; Centrella, Paolo A.; Clark, Matthew A.; Chung, Chun-wa; Davie, Christopher P.; Delorey, Jennifer L.; Ding, Yun; Franklin, G. Joseph; Grady, LaShadric C.; Herry, Kenny; Hobbs, Clare; Kollmann, Christopher S.; Morgan, Barry A.; Kaushansky, Laura J. (Pothier); Zhou, Quan
分享
收藏Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT)通过DNA编码文库技术 (ELT) 发现ADAMTS-4的有效和选择性抑制剂
Ding, Yun; O'Keefe, Heather; DeLorey, Jennifer L.; Israebt, David I.; Messer, Jeffrey A.; Chiu, Cynthia H.; Skinner, Steven R.; Matico, Rosalie E.; Murray-Thompson, Monique F.; Li, Fan; Clark, Matthew A.; Cuozzo, John W.; Arico-Muendel, Christopher; Morgan, Barry A.
分享
收藏Effective biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate by supplementation of L-glutamine, D-xylose and β-cyclodextrin in n-butyl acetate-water media通过在乙酸正丁酯-水介质中补充L-谷氨酰胺,D-木糖和 β-环糊精有效生物合成 (R)-4-氯-3-羟基丁酸乙酯
He, Yu-Cai; Tao, Zhi-Cheng; Ding, Yun; Zhang, Dan-Ping; Wu, Yin-Qin; Lu, Yun; Liu, Feng; Xue, Yu-Feng; Wang, Cheng; Xu, Jian-He
分享
收藏Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)
Yang, Hongfang; Medeiros, Patricia F.; Raha, Kaushik; Elkins, Patricia; Lind, Kenneth E.; Lehr, Ruth; Adams, Nicholas D.; Burgess, Joelle L.; Schmidt, Stanley J.; Knight, Steven D.; Auger, Kurt R.; Schaber, Michael D.; Franklin, G. Joseph; Ding, Yun; DeLorey, Jennifer L.; Centrella, Paolo A.; Mataruse, Sibongile; Skinner, Steven R.; Clark, Matthew A.; Cuozzo, John W.; Evindar, Ghotas
分享
收藏Improved biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by adding L-glutamine plus glycine instead of NAD+ in β-cyclodextrin-water system通过在 β-环糊精-水体系中添加L-谷氨酰胺和甘氨酸代替NAD来改善 (S)-4-氯-3-羟基丁酸乙酯的生物合成
He, Yu-Cai; Zhang, Dan-Ping; Tao, Zhi-Cheng; Lu, Yun; Ding, Yun; Liu, Feng; Zhu, Zheng-Zhong; Rui, Huan; Zheng, Gao-Wei; Zhang, Xian
分享
收藏
分享
收藏
分享
收藏
分享
收藏
分享
收藏