Heiko Zettl - Publications, H-index & Citations

Heiko Zettl

boehringer ingelheim

28H指数

120论文数

3.3K被引数

收录论文 36

发表时间

Correction: Epidemiology and Real-World Outcomes in Patients with Human Epidermal Growth Factor Receptor 2 (HER2)-Mutant Non-small Cell Lung Cancer by Region: A Targeted Literature Review 纠正：人表皮生长因子受体2（HER2）突变非小细胞肺癌患者的流行病学和真实世界结局的区域差异：一项靶向性文献综述

Targeted Oncology

IF4

2026-06-30

OAAI

Koichi Goto; Hidetoshi Hayashi; Sonia S. Maruti; Heiko Zettl; Lalith Mittal; Smit Pathak; Xiuning Le

Acceptable respondent burden in patient-reported outcome (PRO) assessment in oncology clinical trials: a mixed methods study with patients and trialists 在肿瘤学临床试验中患者报告结局（PRO）评估的可接受应答负担：一项结合患者和试验者的混合方法研究

Journal of Patient-Reported Outcomes

IF2.9

2026-02-19

PREAI

Yurdakul, Selin; Georgiadis, Alexandros; Sandy, Bert; Zettl, Heiko; Wong, Brendon; Ingelgard, Anders

Flexible, Heat-Resistant, and Flame-Retardant Glass Fiber Nonwoven/Glass Platelet Composite Separator for Lithium-Ion Batteries

ENERGIES

IF3.2

2018-04-20

OAAI

Schadeck, Ulrich; Kyrgyzbaev, Kanat; Zettl, Heiko; Gerdes, Thorsten; Moos, Ralf

Structural Basis for the Regulation of the Mitogen-activated Protein (MAP) Kinase p38α by the Dual Specificity Phosphatase 16 MAP Kinase Binding Domain in Solution

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-09-01

OAAI

Kumar, Ganesan Senthil; Zettl, Heiko; Page, Rebecca; Peti, Wolfgang

Discovery of γ-Secretase Modulators with a Novel Activity Profile by Text-Based Virtual Screening 通过基于文本的虚拟筛选发现具有新颖活性谱的 γ-分泌酶调节剂

ACS CHEMICAL BIOLOGY

IF3.8

2012-07-02

PREAI

Zettl, Heiko; Ness, Julia; Haehnke, Volker; Beher, Dirk; Jumpertz, Thorsten; Saric, Arman; Baumann, Karlheinz; Pietrzik, Claus U.; Bulic, Bruno; Schneider, Gisbert; Weggen, Sascha

SAR studies of acidic dual γ-secretase/PPARγ modulators 酸性双 γ-分泌酶/ppar γ 调节剂的SAR研究

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2011-09-01

PREAI

Hieke, Martina; Ness, Julia; Steri, Ramona; Greiner, Christine; Werz, Oliver; Schubert-Zsilavecz, Manfred; Weggen, Sascha; Zettl, Heiko

2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52) - a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivo

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2011-08-28

OAAI

Greiner, C.; Hoernig, C.; Rossi, A.; Pergola, C.; Zettl, H.; Schubert-Zsilavecz, M.; Steinhilber, D.; Sautebin, L.; Werz, O.

Identification of 2-mercaptohexanoic acids as dual inhibitors of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2011-06-01

PREAI

Greiner, Christine; Zettl, Heiko; Koeberle, Andreas; Pergola, Carlo; Northoff, Hinnak; Schubert-Zsilavecz, Manfred; Werz, Oliver

Reaction-driven de novo design, synthesis and testing of potential type II kinase inhibitors

FUTURE MEDICINAL CHEMISTRY

IF3.4

2011-03-31

PREAI

Schneider, Gisbert; Geppert, Tim; Hartenfeller, Markus; Reisen, Felix; Klenner, Alexander; Reutlinger, Michael; Haehnke, Volker; Hiss, Jan A.; Zettl, Heiko; Keppner, Sarah; Spaenkuch, Birgit; Schneider, Petra

Exploring the chemical space of γ-secretase modulators 探索 γ-分泌酶调节剂的化学空间

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2010-09-01

PREAI

Zettl, Heiko; Weggen, Sascha; Schneider, Petra; Schneider, Gisbert

Design, Synthesis, and Biological Evaluation of a Novel Class of γ-Secretase Modulators with PPARγ Activity 一类具有ppar γ 活性的新型 γ-分泌酶调节剂的设计、合成及生物学评价

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2010-05-26

PREAI

Hieke, Martina; Ness, Julia; Steri, Ramona; Dittrich, Michaela; Greiner, Christine; Werz, Oliver; Baumann, Karlheinz; Schubert-Zsilavecz, Manfred; Weggen, Sascha; Zettl, Heiko

Electric Field Induced Gyroid-to-Cylinder Transitions in Concentrated Diblock Copolymer Solutions

MACROMOLECULES

IF5.2

2010-04-14

PREAI

Schmidt, Kristin; Pester, Christian W.; Schoberth, Heiko G.; Zettl, Heiko; Schindler, Kerstin A.; Boeker, Alexander

The Molecular Pharmacology and In Vivo Activity of 2-(4-Chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a Dual Inhibitor of Microsomal Prostaglandin E2 Synthase-1 and 5-Lipoxygenase

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2010-03-01

PREAI

Koeberle, Andreas; Rossi, Antonietta; Zettl, Heiko; Pergola, Carlo; Dehm, Friederike; Bauer, Julia; Greiner, Christine; Reckel, Sina; Hoernig, Christina; Northoff, Hinnak; Bernhard, Frank; Doetsch, Volker; Sautebin, Lidia; Schubert-Zsilavecz, Manfred; Werz, Oliver

Enantiomer separation and indirect chromatographic absolute configuration prediction of chiral pirinixic acid derivatives: Limitations of polysaccharide-type chiral stationary phases in comparison to chiral anion-exchangers

JOURNAL OF CHROMATOGRAPHY A

IF4

2010-02-01

PREAI

Laemmerhofer, Michael; Pell, Reinhard; Mahut, Marek; Richter, Martin; Schiesel, Simone; Zettl, Heiko; Dittrich, Michaela; Schubert-Zsilavecz, Manfred; Lindner, Wolfgang

From Machine Learning to Natural Product Derivatives that Selectively Activate Transcription Factor PPARγ 从机器学习到选择性激活转录因子ppar γ 的天然产物衍生物

CHEMMEDCHEM

IF3.4

2010-01-26

PREAI

Rupp, Matthias; Schroeter, Timon; Steri, Ramona; Zettl, Heiko; Proschak, Ewgenij; Hansen, Katja; Rau, Oliver; Schwarz, Oliver; Mueller-Kuhrt, Lutz; Schubert-Zsilavecz, Manfred; Mueller, Klaus-Robert; Schneider, Gisbert

Medicinal Chemistry of Incretin Mimetics and DPP-4 Inhibitors

CHEMMEDCHEM

IF3.4

2010-01-26

PREAI

Zettl, Heiko; Schubert-Zsilavecz, Manfred; Steinhilber, Dieter

Nonacidic Inhibitors of Human Microsomal Prostaglandin Synthase 1 (mPGES 1) Identified by a Multistep Virtual Screening Protocol

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-12-21

PREAI

Roersch, Florian; Wobst, Ivonne; Zettl, Heiko; Schubert-Zsilavecz, Manfred; Groesch, Sabine; Geisslinger, Gerd; Schneider, Gisbert; Proschak, Ewgenij

Nonsteroidal Anti-Inflammatory Drugs: A Critical Review on Current Concepts Applied to Reduce Gastrointestinal Toxicity

CURRENT MEDICINAL CHEMISTRY

IF3.5

2009-06-01

PREAI

Abdel-Tawab, Mona; Zettl, Heiko; Schubert-Zsilavecz, Manfred

From Molecular Shape to Potent Bioactive Agents II: Fragment-Based de novo Design 从分子形状到有效的生物活性剂II: 基于片段的从头设计

CHEMMEDCHEM

IF3.4

2009-01-05

PREAI

Proschak, Ewgenij; Sander, Kerstin; Zettl, Heiko; Tanrikulu, Yusuf; Rau, Oliver; Schneider, Petra; Schubert-Zsilavecz, Manfred; Stark, Holger; Schneider, Gisbert

From Molecular Shape to Potent Bioactive Agents I: Bioisosteric Replacement of Molecular Fragments

CHEMMEDCHEM

IF3.4

2009-01-05

PREAI

Proschak, Ewgenij; Zettl, Heiko; Tanrikulu, Yusuf; Weisel, Martin; Kriegl, Jan M.; Rau, Oliver; Schubert-Zsilavecz, Manfred; Schneider, Gisbert

研究方向