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收藏MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects
Anttila, Jenni E.; Mattila, Olli S.; Liew, Hock-Kean; Maetlik, Kert; Mervaala, Eero; Lindholm, Paeivi; Lindahl, Maria; Lindsberg, Perttu J.; Tseng, Kuan-Yin; Airavaara, Mikko 分享 收藏 分享 收藏 CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stressCDNF通过靶向内质网应激挽救肌萎缩侧索硬化模型中的运动神经元De Lorenzo, Francesca; Luningschror, Patrick; Nam, Jinhan; Beckett, Liam; Pilotto, Federica; Galli, Emilia; Lindholm, Paivi; von Collenberg, Cora Rudt; Mungwa, Simon Tii; Jablonka, Sibylle; Kauder, Julia; Thau-Habermann, Nadine; Petri, Susanne; Lindholm, Dan; Saxena, Smita; Sendtner, Michael; Saarma, Mart; Voutilainen, Merja H. 分享 收藏 MANF regulates neuronal survival and UPR through its ER-located receptor IRE1aKovaleva, Vera; Yu, Li-Ying; Ivanova, Larisa; Shpironok, Olesya; Nam, Jinhan; Eesmaa, Ave; Kumpula, Esa-Pekka; Sakson, Sven; Toots, Urve; Ustav, Mart; Huiskonen, Juha T.; Voutilainen, Merja H.; Lindholm, Paivi; Karelson, Mati; Saarma, Mart 分享 收藏 分享 收藏 分享 收藏 The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactorEesmaa, Ave; Yu, Li-Ying; Goos, Helka; Noges, Kristofer; Kovaleva, Vera; Hellman, Maarit; Zimmermann, Richard; Jung, Martin; Permi, Perttu; Varjosalo, Markku; Lindholm, Paivi; Saarma, Mart 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in Parkinson's disease帕金森氏病海马中胶质细胞源性神经营养因子水平降低，但成纤维细胞生长因子2和脑多巴胺神经营养因子水平升高Virachit, Sophie; Mathews, Kathryn J.; Cottam, Veronica; Werry, Eryn; Galli, Emilia; Rappou, Elisabeth; Lindholm, Paivi; Saarma, Mart; Halliday, Glenda M.; Weickert, Cynthia Shannon; Double, Kay L. 分享 收藏 分享 收藏 Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetesBalboa, Diego; Saarimaki-Vire, Jonna; Borshagovski, Daniel; Survila, Mantas; Lindholm, Paivi; Galli, Emilia; Eurola, Solja; Ustinov, Jarkko; Grym, Heli; Huopio, Hanna; Partanen, Juha; Wartiovaara, Kirmo; Otonkoski, Timo 分享 收藏 MANF protects human pancreatic beta cells against stress-induced cell deathHakonen, Elina; Chandra, Vikash; Fogarty, Christopher L.; Yu, Nancy Yiu-Lin; Ustinov, Jarkko; Katayama, Shintaro; Galli, Emilia; Danilova, Tatiana; Lindholm, Paivi; Vartiainen, Aki; Einarsdottir, Elisabet; Krjutskov, Kaarel; Kere, Juha; Saarma, Mart; Lindahl, Maria; Otonkoski, Timo 分享 收藏 Poststroke delivery of MANF promotes functional recovery in ratsMatlik, Kert; Anttila, Jenni E.; Kuan-Yin, Tseng; Smolander, Olli-Pekka; Pakarinen, Emmi; Lehtonen, Leevi; Abo-Ramadan, Usama; Lindholm, Paivi; Zheng, Congjun; Harvey, Brandon; Arumae, Urmas; Lindahl, Maria; Airavaara, Mikko 分享 收藏 分享 收藏 Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetesGalli, Emilia; Harkonen, Taina; Sainio, Markus T.; Ustav, Mart; Toots, Urve; Urtti, Arto; Yliperttula, Marjo; Lindahl, Maria; Knip, Mikael; Saarma, Mart; Lindholm, Paivi 分享 收藏 Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activityMatlik, K.; Yu, Li-ying; Eesmaa, A.; Hellman, M.; Lindholm, P.; Peranen, J.; Galli, E.; Anttila, J.; Saarma, M.; Permi, P.; Airavaara, M.; Arumae, U. 分享 收藏 分享 收藏 
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