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Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis Serrano, Sonia Simon; Gronberg, Alvar; Longato, Lisa; Rombouts, Krista; Kuo, Joseph; Gregory, Matthew; Moss, Steven; Elmer, Eskil; Mazza, Giuseppe; Gallay, Philippe; Pinzani, Massimo; Hansson, Magnus J.; Massoumi, Ramin 分享 收藏
Diversity oriented biosynthesis via accelerated evolution of modular gene clusters Wlodek, Aleksandra; Kendrew, Steve G.; Coates, Nigel J.; Hold, Adam; Pogwizd, Joanna; Rudder, Steven; Sheehan, Lesley S.; Higginbotham, Sarah J.; Stanley-Smith, Anna E.; Warneck, Tony; Nur-E-Alam, Mohammad; Radzom, Markus; Martin, Christine J.; Overvoorde, Lois; Samborskyy, Markiyan; Alt, Silke; Heine, Daniel; Carter, Guy T.; Graziani, Edmund I.; Koehn, Frank E.; McDonald, Leonard; Alanine, Alexander; Sarmiento, Rosa Maria Rodriguez; Chao, Suzan Keen; Ratni, Hasane; Steward, Lucinda; Norville, Isobel H.; Sarkar-Tyson, Mitali; Moss, Steven J.; Leadlay, Peter F.; Wilkinson, Barrie; Gregory, Matthew A. 分享 收藏
Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency Ehinger, Johannes K.; Piel, Sarah; Ford, Rhonan; Karlsson, Michael; Sjoevall, Fredrik; Frostner, Eleonor Asander; Morota, Saori; Taylor, Robert W.; Turnbull, Doug M.; Cornell, Clive; Moss, Steven J.; Metzsch, Carsten; Hansson, Magnus J.; Fliri, Hans; Elmer, Eskil 分享 收藏
Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo Maria Novoa, Eva; Camacho, Noelia; Tor, Anna; Wilkinson, Barrie; Moss, Steven; Marin-Garcia, Patricia; Azcarate, Isabel G.; Bautista, Jose M.; Mirando, Adam C.; Francklyn, Christopher S.; Varon, Sonia; Royo, Miriam; Cortes, Alfred; Ribas de Pouplana, Lluis 分享 收藏
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Structure guided design of improved anti-proliferative rapalogs through biosynthetic medicinal chemistry Gregory, Matthew A.; Kaja, Andrew L.; Kendrew, Steven G.; Coates, Nigel J.; Warneck, Tony; Nur-e-Alam, Mohammad; Lill, Rachel E.; Sheehan, Lesley S.; Chudley, Lindsey; Moss, Steven J.; Sheridan, Rose M.; Quimpere, Miguel; Zhang, Ming-Qiang; Martin, Christine J.; Wilkinson, Barrie 分享 收藏
Recombinant strains for the enhanced production of bioengineered rapalogs Kendrew, Steven G.; Petkovic, Hrvoje; Gaisser, Sabine; Ready, Sarah J.; Gregory, Matthew A.; Coates, Nigel J.; Nur-e-Alam, Mohammad; Warneck, Tony; Suthar, Dipen; Foster, Teresa A.; McDonald, Leonard; Schlingman, Gerhard; Koehn, Frank E.; Skotnicki, Jerauld S.; Carter, Guy T.; Moss, Steven J.; Zhang, Ming-Qiang; Martin, Christine J.; Sheridan, Rose M.; Wilkinson, Barrie 分享 收藏
BC556, A POTENT, PAN-GENOTYPIC, HIGH BARRIER TO RESISTANCE, SECOND GENERATION CYCLOPHILIN INHIBITOR FOR TREATMENT OF CHRONIC HCV INFECTION Moss, S. J.; Garcia-Rivera, J. A.; Leyssen, P.; Coates, N.; Foster, T.; Kendrew, S.; Nur-E-Alam, M.; Stanley, A. E.; Suthar, D.; Warneck, T.; Neyts, J.; Gallay, P.; Wilkinson, B.; Gregory, M. A. 分享 收藏
Preclinical Characterization of Naturally Occurring Polyketide Cyclophilin Inhibitors from the Sanglifehrin Family 来自Sanglifehrin家族的天然聚酮亲环素抑制剂的临床前表征 Gregory, Matthew A.; Bobardt, Michael; Obeid, Susan; Chatterji, Udayan; Coates, Nigel J.; Foster, Teresa; Gallay, Philippe; Leyssen, Pieter; Moss, Steven J.; Neyts, Johan; Nur-e-Alam, Mohammad; Paeshuyse, Jan; Piraee, Mahmood; Suthar, Dipen; Warneck, Tony; Zhang, Ming-Qiang; Wilkinson, Barrie 分享 收藏
Total Synthesis of Chloptosin: A Dimeric Cyclohexapeptide Oelke, Alexander J.; Antonietti, Francesca; Bertone, Leonardo; Cranwell, Philippa B.; France, David J.; Goss, Rebecca J. M.; Hofmann, Tatjana; Knauer, Stephan; Moss, Steven J.; Skelton, Paul C.; Turner, Richard M.; Wuitschik, Georg; Ley, Steven V. 分享 收藏
Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate Andexer, Jennifer N.; Kendrew, Steven G.; Nur-e-Alam, Mohammad; Lazos, Orestis; Foster, Teresa A.; Zimmermann, Anna-Sophie; Warneck, Tony D.; Suthar, Dipen; Coates, Nigel J.; Koehn, Frank E.; Skotnicki, Jerauld S.; Carter, Guy T.; Gregory, Matthew A.; Martin, Christine J.; Moss, Steven J.; Leadlay, Peter F.; Wilkinson, Barrie 分享 收藏
PRECLINICAL CHARACTERIZATION OF NOVEL CYCLOPHILIN INHIBITORS BASED ON THE POLYKETIDE, SANGLIFEHRIN Moss, S. J.; Bobardt, M.; Coates, N.; Chatterji, U.; Foster, T.; Gallay, P.; Habel, A.; Kendrew, S.; Leyssen, P.; Martin, C. J.; Neyts, J.; Nur-e-Alam, M.; Obeid, S.; Paeshuyse, J.; Suthar, D.; Warneck, T.; Wilkinson, B.; Gregory, M. A. 分享 收藏
Optimizing natural products by biosynthetic engineering: Discovery of nonquinone Hsp90 inhibitors Zhang, Ming-Qiang; Gaisser, Sabine; Nur-E-Alam, Mohammad; Sheehan, Lesley S.; Vousden, William A.; Gaitatzis, Nikolaos; Peck, Gerrard; Coates, Nigel J.; Moso, Steven J.; Radzom, Markus; Foster, Teresa A.; Sheridan, Rose M.; Gregory, Matthew A.; Roe, S. Mark; Prodromou, Chrisostomos; Pearl, Laurence; Boyd, Susan M.; Wilkinson, Barrie; Martin, Christine J. 分享 收藏
On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of glycolate units into ansamitocin and soraphen A Wenzel, Silke C.; Williamson, Rachel M.; Gruenanger, Christian; Xu, Jun; Gerth, Klaus; Martinez, Rodolfo A.; Moss, Steven J.; Carroll, Brian J.; Grond, Stephanie; Unkefer, Clifford J.; Mueller, Rolf; Floss, Heinz G. 分享 收藏
Biosynthesis of the angiogenesis inhibitor borrelidin:: directed biosynthesis of novel analogues Moss, Steven J.; Carletti, Isabelle; Olano, Carlos; Sheridan, Rose M.; Ward, Michael; Math, Vidya; Nur-E-Alam, Mohammad; Brana, Alfredo F.; Zhang, Ming Qiang; Leadlay, Peter F.; Mendez, Carmen; Salas, Jose A.; Wilkinson, Barrie 分享 收藏
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