Paul J. Lombroso - Publications, H-index & Citations

Paul J. Lombroso

Yale University

58H指数

270论文数

1.2W被引数

收录论文 68

发表时间

Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain

BRAIN

IF11.7

2022-03-23

OAAI

Dedek, Annemarie; Xu, Jian; Lorenzo, Louis-Etienne; Godin, Antoine G.; Kandegedara, Chaya M.; Glavina, Genevieve; Landrigan, Jeffrey A.; Lombroso, Paul J.; De Koninck, Yves; Tsai, Eve C.; Hildebrand, Michael E.

Loss of STEP61 couples disinhibition to N-methyl-D-aspartate receptor potentiation in rodent and human spinal pain processing

BRAIN

IF11.7

2019-05-28

OAAI

Dedek, Annemarie; Xu, Jian; Kandegedara, Chaya M.; Lorenzo, Louis-Etienne; Godin, Antoine G.; De Koninck, Yves; Lombroso, Paul J.; Tsai, Eve C.; Hildebrand, Michael E.

The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline

CURRENT BIOLOGY

IF7.5

2018-04-01

OAAI

Castonguay, David; Dufort-Gervais, Julien; Menard, Caroline; Chatterjee, Manavi; Quirion, Remi; Bontempi, Bruno; Schneider, Jay S.; Arnsten, Amy F. T.; Nairn, Angus C.; Norris, Christopher M.; Ferland, Guylaine; Bezard, Erwan; Gaudreau, Pierrette; Lombroso, Paul J.; Brouillette, Jonathan

Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases

ACS CENTRAL SCIENCE

IF10.4

2017-12-06

OAAI

Tjin, Caroline Chandra; Otley, Kate D.; Baguley, Tyler D.; Kurup, Pradeep; Xu, Jian; Nairn, Angus C.; Lombroso, Paul J.; Ellman, Jonathan A.

X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-11-08

OAAI

Witten, Michael R.; Wissler, Lisa; Snow, Melanie; Geschwindner, Stefan; Read, Jon A.; Brandon, Nicholas J.; Nairn, Angus C.; Lombroso, Paul J.; Kack, Helena; Ellman, Jonathan A.

Intra-prelimbic cortical inhibition of striatal-enriched tyrosine phosphatase suppresses cocaine seeking in rats

ADDICTION BIOLOGY

IF2.6

2017-03-28

OAAI

Siemsen, Ben M.; Lombroso, Paul J.; McGinty, Jacqueline F.

Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing

CELL REPORTS

IF6.9

2016-12-01

111

OAAI

Hildebrand, Michael E.; Xu, Jian; Dedek, Annemarie; Li, Yi; Sengar, Ameet S.; Beggs, Simon; Lombroso, Paul J.; Salter, Michael W.

STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit

SCIENTIFIC REPORTS

IF3.9

2016-11-18

OAAI

Tian, Meng; Xu, Jian; Lei, Gang; Lombroso, Paul J.; Jackson, Michael F.; MacDonald, John F.

Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models

MOLECULAR PSYCHIATRY

IF10.1

2016-10-18

OAAI

Xu, J.; Hartley, B. J.; Kurup, P.; Phillips, A.; Topol, A.; Xu, M.; Ononenyi, C.; Foscue, E.; Ho, S-M; Baguley, T. D.; Carty, N.; Barros, C. S.; Muller, U.; Gupta, S.; Gochman, P.; Rapoport, J.; Ellman, J. A.; Pittenger, C.; Aronow, B.; Nairn, A. C.; Nestor, M. W.; Lombroso, P. J.; Brennand, K. J.

Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition

PAIN

IF5.5

2016-02-01

OAAI

Azkona, Garikoitz; Saavedra, Ana; Aira, Zigor; Aluja, David; Xifro, Xavier; Baguley, Tyler; Alberch, Jordi; Ellman, Jonathan A.; Lombroso, Paul J.; Azkue, Jon J.; Perez-Navarro, Esther

Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function

NEURAL PLASTICITY

IF3.7

2016-01-01

OAAI

Kamceva, Marija; Benedict, Jessie; Nairn, Angus C.; Lombroso, Paul J.

Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2015-10-08

OAAI

Xu, Jian; Kurup, Pradeep; Baguley, Tyler D.; Foscue, Ethan; Ellman, Jonathan A.; Nairn, Angus C.; Lombroso, Paul J.

Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity

MOLECULAR BRAIN

IF2.9

2015-09-22

OAAI

Jang, Sung-Soo; Royston, Sara E.; Xu, Jian; Cavaretta, John P.; Vest, Max O.; Lee, Kwan Young; Lee, Seungbae; Jeong, Han Gil; Lombroso, Paul J.; Chung, Hee Jung

STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease STEP61是E3连接酶parkin的底物，在帕金森氏病中上调

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-01-12

OAAI

Kurup, Pradeep K.; Xu, Jian; Videira, Rita Alexandra; Ononenyi, Chimezie; Baltazar, Graca; Lombroso, Paul J.; Nairn, Angus C.

Substrate-Based Fragment Identification for the Development of Selective, Nonpeptidic Inhibitors of Striatal-Enriched Protein Tyrosine Phosphatase (vol 56, pg 7636, 2013)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-12-12

OAAI

Baguley, Tyler D.; Xu, Hai-Chao; Chatterjee, Manavi; Nairn, Angus C.; Lombroso, Paul J.; Ellman, Jonathan A.

The role of STEP in Alzheimer's disease STEP在阿尔茨海默病中的作用

CHANNELS

IF3.2

2014-11-04

OAAI

Kurup, Pradeep; Zhang, Yongfang; Venkitaramani, Deepa V.; Xu, Jian; Lombroso, Paul J.

Rapid regulation of endoplasmic reticulum dynamics in dendritic spines by NMDA receptor activation

MOLECULAR BRAIN

IF2.9

2014-08-19

OAAI

Ng, Ai Na; Doherty, Andrew J.; Lombroso, Paul J.; Emptage, Nigel J.; Collingridge, Graham L.

Striatal-Enriched Protein Tyrosine Phosphatase-STEPs Toward Understanding Chronic Stress-Induced Activation of Corticotrophin Releasing Factor Neurons in the Rat Bed Nucleus of the Stria Terminalis

BIOLOGICAL PSYCHIATRY

IF9

2013-12-01

OAAI

Dabrowska, Joanna; Hazra, Rimi; Guo, Ji-Dong; Li, ChenChen; DeWitt, Sarah; Xu, Jian; Lombroso, Paul J.; Rainnie, Donald G.

Substrate-Based Fragment Identification for the Development of Selective, Nonpeptidic Inhibitors of Striatal-Enriched Protein Tyrosine Phosphatase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-10-01

OAAI

Baguley, Tyler D.; Xu, Hai-Chao; Chatterjee, Manavi; Nairn, Angus C.; Lombroso, Paul J.; Ellman, Jonathan A.

Cocaine-Induced Changes of Synaptic Transmission in the Striatum are Modulated by Adenosine A2A Receptors and Involve the Tyrosine Phosphatase STEP

NEUROPSYCHOPHARMACOLOGY

IF7.1

2013-08-30

OAAI

Chiodi, Valentina; Mallozzi, Cinzia; Ferrante, Antonella; Chen, Jiang F.; Lombroso, Paul J.; Di Stasi, Anna Maria Michela; Popoli, Patrizia; Domenici, Maria Rosaria

研究方向