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收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry评估构建非洲和欧洲血统男性前列腺癌多基因风险评分的方法
Darst, Burcu F.; Shen, Jiayi; Madduri, Ravi K.; Rodriguez, Alexis A.; Xiao, Yukai; Sheng, Xin; Saunders, Edward J.; Dadaev, Tokhir; Brook, Mark N.; Hoffmann, Thomas J.; Muir, Kenneth; Wan, Peggy; Le Marchand, Loic; Wilkens, Lynne; Wang, Ying; Schleutker, Johanna; MacInnis, Robert J.; Cybulski, Cezary; Neal, David E.; Nordestgaard, Borge G.; Nielsen, Sune F.; Batra, Jyotsna; Clements, Judith A.; Gronberg, Henrik; Pashayan, Nora; Travis, Ruth C.; Park, Jong Y.; Albanes, Demetrius; Weinstein, Stephanie; Mucci, Lorelei A.; Hunter, David J.; Penney, Kathryn L.; Tangen, Catherine M.; Hamilton, Robert J.; Parent, Marie-Elise; Stanford, Janet L.; Koutros, Stella; Wolk, Alicja; Sorensen, Karina D.; Blot, William J.; Yeboah, Edward D.; Mensah, James E.; Lu, Yong-Jie; Schaid, Daniel J.; Thibodeau, Stephen N.; West, Catharine M.; Maier, Christiane; Kibel, Adam S.; Cancel-Tassin, Geraldine; Menegaux, Florence; John, Esther M.; Grindedal, Eli Marie; Khaw, Kay-Tee; Ingles, Sue A.; Vega, Ana; Rosenstein, Barry S.; Teixeira, Manuel R.; Kogevinas, Manoli; Cannon-Albright, Lisa; Huff, Chad; Multigner, Luc; Kaneva, Radka; Leach, Robin J.; Brenner, Hermann; Hsing, Ann W.; Kittles, Rick A.; Murphy, Adam B.; Logothetis, Christopher J.; Neuhausen, Susan L.; Isaacs, William B.; Nemesure, Barbara; Hennis, Anselm J.; Carpten, John; Pandha, Hardev; De Ruyck, Kim; Xu, Jianfeng; Razack, Azad; Teo, Soo-Hwang; Newcomb, Lisa F.; Fowke, Jay H.; Neslund-Dudas, Christine; Rybicki, Benjamin A.; Gamulin, Marija; Usmani, Nawaid; Claessens, Frank; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Townsend, Paul A.; Crawford, Dana C.; Petrovics, Gyorgy; Casey, Graham; Roobol, Monique J.; Hu, Jennifer F.; Berndt, Sonja I.; van den Eeden, Stephen K.; Easton, Douglas F.; Chanock, Stephen J.; Cook, Michael B.; Wiklund, Fredrik; Witte, John S.; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Watya, Stephen; Gaziano, John M.; Justice, Amy C.; Conti, David V.; Haiman, Christopher A. 分享 收藏 Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score使用新的多基因风险评分改善多个祖先的前列腺癌风险分层Minh-Phuong Huynh-Le; Karunamuni, Roshan; Fan, Chun Chieh; Asona, Lui; Thompson, Wesley K.; Martinez, Maria Elena; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Muir, Kenneth R.; Lophatananon, Artitaya; Schleutker, Johanna; Pashayan, Nora; Batra, Jyotsna; Groenberg, Henrik; Neal, David E.; Nordestgaard, Borge G.; Tangen, Catherine M.; MacInnis, Robert J.; Wolk, Alicja; Albanes, Demetrius; Haiman, Christopher A.; Travis, Ruth C.; Blot, William J.; Stanford, Janet L.; Mucci, Lorelei A.; West, Catharine M. L.; Nielsen, Sune F.; Kibel, Adam S.; Cussenot, Olivier; Berndt, Sonja, I; Koutros, Stella; Sorensen, Karina Dalsgaard; Cybulski, Cezary; Grindedal, Eli Marie; Menegaux, Florence; Park, Jong Y.; Ingles, Sue A.; Maier, Christiane; Hamilton, Robert J.; Rosenstein, Barry S.; Lu, Yong-Jie; Watya, Stephen; Vega, Ana; Kogevinas, Manolis; Wiklund, Fredrik; Penney, Kathryn L.; Huff, Chad D.; Teixeira, Manuel R.; Multigner, Luc; Leach, Robin J.; Brenner, Hermann; John, Esther M.; Kaneva, Radka; Logothetis, Christopher J.; Neuhausen, Susan L.; De Ruyck, Kim; Ost, Piet; Razack, Azad; Newcomb, Lisa F.; Fowke, Jay H.; Gamulin, Marija; Abraham, Aswin; Claessens, Frank; Castelao, Jose Esteban; Townsend, Paul A.; Crawford, Dana C.; Petrovics, Gyorgy; van Schaik, Ron H. N.; Parent, Marie-Elise; Hu, Jennifer J.; Zheng, Wei; Mills, Ian G.; Andreassen, Ole A.; Dale, Anders M.; Seibert, Tyler M. 分享 收藏 分享 收藏 分享 收藏 KLK3 SNP-SNP interactions for prediction of prostate cancer aggressivenessLin, Hui-Yi; Huang, Po-Yu; Cheng, Chia-Ho; Tung, Heng-Yuan; Fang, Zhide; Berglund, Anders E.; Chen, Ann; French-Kwawu, Jennifer; Harris, Darian; Pow-Sang, Julio; Yamoah, Kosj; Cleveland, John L.; Awasthi, Shivanshu; Rounbehler, Robert J.; Gerke, Travis; Dhillon, Jasreman; Eeles, Rosalind; Kote-Jarai, Zsofia; Muir, Kenneth; Schleutker, Johanna; Pashayan, Nora; Neal, David E.; Nielsen, Sune F.; Nordestgaard, Borge G.; Gronberg, Henrik; Wiklund, Fredrik; Giles, Graham G.; Haiman, Christopher A.; Travis, Ruth C.; Stanford, Janet L.; Kibel, Adam S.; Cybulski, Cezary; Khaw, Kay-Tee; Maier, Christiane; Thibodeau, Stephen N.; Teixeira, Manuel R.; Cannon-Albright, Lisa; Brenner, Hermann; Kaneva, Radka; Pandha, Hardev; Srinivasan, Srilakshmi; Clements, Judith; Batra, Jyotsna; Park, Jong Y. 分享 收藏 Polygenic hazard score is associated with prostate cancer in multi-ethnic populations多种族人群的多基因风险评分与前列腺癌相关Huynh-Le, Minh-Phuong; Fan, Chun Chieh; Karunamuni, Roshan; Thompson, Wesley K.; Martinez, Maria Elena; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Muir, Kenneth; Schleutker, Johanna; Pashayan, Nora; Batra, Jyotsna; Gronberg, Henrik; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Martin, Richard M.; Nielsen, Sune F.; Nordestgaard, Borge G.; Wiklund, Fredrik; Tangen, Catherine M.; Giles, Graham G.; Wolk, Alicja; Albanes, Demetrius; Travis, Ruth C.; Blot, William J.; Zheng, Wei; Sanderson, Maureen; Stanford, Janet L.; Mucci, Lorelei A.; West, Catharine M. L.; Kibel, Adam S.; Cussenot, Olivier; Berndt, Sonja I.; Koutros, Stella; Sorensen, Karina Dalsgaard; Cybulski, Cezary; Grindedal, Eli Marie; Menegaux, Florence; Khaw, Kay-Tee; Park, Jong Y.; Ingles, Sue A.; Maier, Christiane; Hamilton, Robert J.; Thibodeau, Stephen N.; Rosenstein, Barry S.; Lu, Yong-Jie; Watya, Stephen; Vega, Ana; Kogevinas, Manolis; Penney, Kathryn L.; Huff, Chad; Teixeira, Manuel R.; Multigner, Luc; Leach, Robin J.; Cannon-Albright, Lisa; Brenner, Hermann; John, Esther M.; Kaneva, Radka; Logothetis, Christopher J.; Neuhausen, Susan L.; De Ruyck, Kim; Pandha, Hardev; Razack, Azad; Newcomb, Lisa F.; Fowke, Jay H.; Gamulin, Marija; Usmani, Nawaid; Claessens, Frank; Gago-Dominguez, Manuela; Townsend, Paul A.; Bush, William S.; Roobol, Monique J.; Parent, Marie-Elise; Hu, Jennifer J.; Mills, Ian G.; Andreassen, Ole A.; Dale, Anders M.; Seibert, Tyler M. 分享 收藏 Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction前列腺癌的跨祖先全基因组关联荟萃分析确定了新的易感位点并为遗传风险预测提供了信息Conti, David, V; Darst, Burcu F.; Moss, Lilit C.; Saunders, Edward J.; Sheng, Xin; Chou, Alisha; Schumacher, Fredrick R.; Al Olama, Ali Amin; Benlloch, Sara; Dadaev, Tokhir; Brook, Mark N.; Sahimi, Ali; Hoffmann, Thomas J.; Takahashi, Atushi; Matsuda, Koichi; Momozawa, Yukihide; Fujita, Masashi; Muir, Kenneth; Lophatananon, Artitaya; Wan, Peggy; Le Marchand, Loic; Wilkens, Lynne R.; Stevens, Victoria L.; Gapstur, Susan M.; Carter, Brian D.; Schleutker, Johanna; Tammela, Teuvo L. J.; Sipeky, Csilla; Auvinen, Anssi; Giles, Graham G.; Southey, Melissa C.; MacInnis, Robert J.; Cybulski, Cezary; Wokolorczyk, Dominika; Lubinski, Jan; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Martin, Richard M.; Nordestgaard, Borge G.; Nielsen, Sune F.; Weischer, Maren; Bojesen, Stig E.; Roder, Martin Andreas; Iversen, Peter; Batra, Jyotsna; Chambers, Suzanne; Moya, Leire; Horvath, Lisa; Clements, Judith A.; Tilley, Wayne; Risbridger, Gail P.; Gronberg, Henrik; Aly, Markus; Szulkin, Robert; Eklund, Martin; Nordstrom, Tobias; Pashayan, Nora; Dunning, Alison M.; Ghoussaini, Maya; Travis, Ruth C.; Key, Tim J.; Riboli, Elio; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Albanes, Demetrius; Weinstein, Stephanie J.; Mucci, Lorelei A.; Giovannucci, Edward; Lindstrom, Sara; Kraft, Peter; Hunter, David J.; Penney, Kathryn L.; Turman, Constance; Tangen, Catherine M.; Goodman, Phyllis J.; Thompson, Ian M., Jr.; Hamilton, Robert J.; Fleshner, Neil E.; Finelli, Antonio; Parent, Marie-Elise; Stanford, Janet L.; Ostrander, Elaine A.; Geybels, Milan S.; Koutros, Stella; Freeman, Laura E. Beane; Stampfer, Meir; Wolk, Alicja; Hakansson, Niclas; Andriole, Gerald L.; Hoover, Robert N.; Machiela, Mitchell J.; Sorensen, Karina Dalsgaard; Borre, Michael; Blot, William J.; Zheng, Wei; Yeboah, Edward D.; Mensah, James E.; Lu, Yong-Jie; Zhang, Hong-Wei; Feng, Ninghan; Mao, Xueying; Wu, Yudong; Zhao, Shan-Chao; Sun, Zan; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; West, Catharine M. L.; Burnet, Neil; Barnett, Gill; Maier, Christiane; Schnoeller, Thomas; Luedeke, Manuel; Kibel, Adam S.; Drake, Bettina F.; Cussenot, Olivier; Cancel-Tassin, Geraldine; Menegaux, Florence; Truong, Therese; Koudou, Yves Akoli; John, Esther M.; Grindedal, Eli Marie; Maehle, Lovise; Khaw, Kay-Tee; Ingles, Sue A.; Stern, Mariana C.; Vega, Ana; Gomez-Caamano, Antonio; Fachal, Laura; Rosenstein, Barry S.; Kerns, Sarah L.; Ostrer, Harry; Teixeira, Manuel R.; Paulo, Paula; Brandao, Andreia; Watya, Stephen; Lubwama, Alexander; Bensen, Jeannette T.; Fontham, Elizabeth T. H.; Mohler, James; Taylor, Jack A.; Kogevinas, Manolis; Llorca, Javier; Castano-Vinyals, Gemma; Cannon-Albright, Lisa; Teerlink, Craig C.; Huff, Chad D.; Strom, Sara S.; Multigner, Luc; Blanchet, Pascal; Brureau, Laurent; Kaneva, Radka; Slavov, Chavdar; Mitev, Vanio; Leach, Robin J.; Weaver, Brandi; Brenner, Hermann; Cuk, Katarina; Holleczek, Bernd; Saum, Kai-Uwe; Klein, Eric A.; Hsing, Ann W.; Kittles, Rick A.; Murphy, Adam B.; Logothetis, Christopher J.; Kim, Jeri; Neuhausen, Susan L.; Steele, Linda; Ding, Yuan Chun; Isaacs, William B.; Nemesure, Barbara; Hennis, Anselm J. M.; Carpten, John; Pandha, Hardev; Michael, Agnieszka; De Ruyck, Kim; De Meerleer, Gert; Ost, Piet; Xu, Jianfeng; Razack, Azad; Lim, Jasmine; Teo, Soo-Hwang; Newcomb, Lisa F.; Lin, Daniel W.; Fowke, Jay H.; Neslund-Dudas, Christine; Rybicki, Benjamin A.; Gamulin, Marija; Lessel, Davor; Kulis, Tomislav; Usmani, Nawaid; Singhal, Sandeep; Parliament, Matthew; Claessens, Frank; Joniau, Steven; Van den Broeck, Thomas; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Martinez, Maria Elena; Larkin, Samantha; Townsend, Paul A.; Aukim-Hastie, Claire; Bush, William S.; Aldrich, Melinda C.; Crawford, Dana C.; Srivastava, Shiv; Cullen, Jennifer C.; Petrovics, Gyorgy; Casey, Graham; Roobol, Monique J.; Jenster, Guido; van Schaik, Ron H. N.; Hu, Jennifer J.; Sanderson, Maureen; Varma, Rohit; McKean-Cowdin, Roberta; Torres, Mina; Mancuso, Nicholas; Berndt, Sonja, I; Van den Eeden, Stephen K.; Easton, Douglas F.; Chanock, Stephen J.; Cook, Michael B.; Wiklund, Fredrik; Nakagawa, Hidewaki; Witte, John S.; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Haiman, Christopher A. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 LOSS-OF-FUNCTION MUTATIONS IN ABCA1, HDL-CHOLESTEROL, METABOLOMIC PROFILES AND RISK OF VASCULAR DISEASE AND DEMENTIA - A COHORT STUDY OF UP TO 100,000 INDIVIDUALSNordestgaard, L. T.; Christoffersen, M.; Afzal, S.; Nielsen, S. F.; Nordestgaard, B. G.; Tybjaerg-Hansen, A.; Frikke-Schmidt, R. 分享 收藏 Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies A Mendelian Randomization AnalysisBurgess, Stephen; Ference, Brian A.; Staley, James R.; Freitag, Daniel F.; Mason, Amy M.; Nielsen, Sune F.; Willeit, Peter; Young, Robin; Surendran, Praveen; Karthikeyan, Savita; Bolton, Thomas R.; Peters, James E.; Kamstrup, Pia R.; Tybjaerg-Hansen, Anne; Benn, Marianne; Langsted, Anne; Schnohr, Peter; Vedel-Krogh, Signe; Kobylecki, Camilla J.; Ford, Ian; Packard, Chris; Trompet, Stella; Jukema, J. Wouter; Sattar, Naveed; Di Angelantonio, Emanuele; Saleheen, Danish; Howson, Joanna M. M.; Nordestgaard, Borge G.; Butterworth, Adam S.; Danesh, John 分享 收藏 Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants大型荟萃分析中前列腺癌易感位点的精细定位可识别候选因果变异Dadaev, Tokhir; Saunders, Edward J.; Newcombe, Paul J.; Anokian, Ezequiel; Leongamornlert, Daniel A.; Brook, Mark N.; Cieza-Borrella, Clara; Mijuskovic, Martina; Wakerell, Sarah; Al Olama, Ali Amin; Schumacher, Fredrick R.; Berndt, Sonja I.; Benlloch, Sara; Ahmed, Mahbubl; Goh, Chee; Sheng, Xin; Zhang, Zhuo; Muir, Kenneth; Govindasami, Koveela; Lophatananon, Artitaya; Stevens, Victoria L.; Gapstur, Susan M.; Carter, Brian D.; Tangen, Catherine M.; Goodman, Phyllis; Thompson, Ian M., Jr.; Batra, Jyotsna; Chambers, Suzanne; Moya, Leire; Clements, Judith; Horvath, Lisa; Tilley, Wayne; Risbridger, Gail; Gronberg, Henrik; Aly, Markus; Nordstrom, Tobias; Pharoah, Paul; Pashayan, Nora; Schleutker, Johanna; Tammela, Teuvo L. J.; Sipeky, Csilla; Auvinen, Anssi; Albanes, Demetrius; Weinstein, Stephanie; Wolk, Alicja; Hakansson, Niclas; West, Catharine; Dunning, Alison M.; Burnet, Neil; Mucci, Lorelei; Giovannucci, Edward; Andriole, Gerald; Cussenot, Olivier; Cancel-Tassin, Geraldine; Koutros, Stella; Freeman, Laura E. Beane; Sorensen, Karina Dalsgaard; Orntoft, Torben Falck; Borre, Michael; Maehle, Lovise; Grindedal, Eli Marie; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Martin, Richard M.; Travis, Ruth C.; Key, Tim J.; Hamilton, Robert J.; Fleshner, Neil E.; Finelli, Antonio; Ingles, Sue Ann; Stern, Mariana C.; Rosenstein, Barry; Kerns, Sarah; Ostrer, Harry; Lu, Yong-Jie; Zhang, Hong-Wei; Feng, Ninghan; Mao, Xueying; Guo, Xin; Wang, Guomin; Sun, Zan; Giles, Graham G.; Southey, Melissa C.; MacInnis, Robert J.; FitzGerald, Liesel M.; Kibel, Adam S.; Drake, Bettina F.; Vega, Ana; Gomez-Caamano, Antonio; Fachal, Laura; Szulkin, Robert; Eklund, Martin; Kogevinas, Manolis; Llorca, Javier; Castano-Vinyals, Gemma; Penney, Kathryn L.; Stampfer, Meir; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Stanford, Janet L.; Cybulski, Cezary; Wokolorczyk, Dominika; Lubinski, Jan; Ostrander, Elaine A.; Geybels, Milan S.; Nordestgaard, Borge G.; Nielsen, Sune F.; Weisher, Maren; Bisbjerg, Rasmus; Roder, Martin Andreas; Iversen, Peter; Brenner, Hermann; Cuk, Katarina; Holleczek, Bernd; Maier, Christiane; Luedeke, Manuel; Schnoeller, Thomas; Kim, Jeri; Logothetis, Christopher J.; John, Esther M.; Teixeira, Manuel R.; Paulo, Paula; Cardoso, Marta; Neuhausen, Susan L.; Steele, Linda; Ding, Yuan Chun; De Ruyck, Kim; De Meerleer, Gert; Ost, Piet; Razack, Azad; Lim, Jasmine; Teo, Soo-Hwang; Lin, Daniel W.; Newcomb, Lisa F.; Lessel, Davor; Gamulin, Marija; Kulis, Tomislav; Kaneva, Radka; Usmani, Nawaid; Slavov, Chavdar; Mitev, Vanio; Parliament, Matthew; Singhal, Sandeep; Claessens, Frank; Joniau, Steven; Van den Broeck, Thomas; Larkin, Samantha; Townsend, Paul A.; Aukim-Hastie, Claire; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Martinez, Maria Elena; Roobol, Monique J.; Jenster, Guido; van Schaik, Ron H. N.; Menegaux, Florence; Truong, Therese; Koudou, Yves Akoli; Xu, Jianfeng; Khaw, Kay-Tee; Cannon-Albright, Lisa; Pandha, Hardev; Michael, Agnieszka; Kierzek, Andrzej; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; Lindstrom, Sara; Turman, Constance; Ma, Jing; Hunter, David J.; Riboli, Elio; Siddiq, Afshan; Canzian, Federico; Kolonel, Laurence N.; Le Marchand, Loic; Hoover, Robert N.; Machiela, Mitchell J.; Kraft, Peter; Freedman, Matthew; Wiklund, Fredrik; Chanock, Stephen; Henderson, Brian E.; Easton, Douglas F.; Haiman, Christopher A.; Eeles, Rosalind A.; Conti, David V.; Kote-Jarai, Zsofia 分享 收藏 分享 收藏 
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