Markus Frericks - Publications, H-index & Citations

Markus Frericks

Novartis

12H指数

60论文数

585被引数

收录论文 23

发表时间

A Simple Framework for Collaborative Development of Predictive Models Trained on Proprietary Data 一个简单的框架，用于基于专有数据训练的预测模型的协作开发

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2025-11-01

PREAI

Rodriguez-Belenguer, Pablo; Amberg, Alexander; Bringezu, Frank; Frericks, Markus; Hemmerich, Jennifer; Monecke, Peter; Oberhauser, Nils; Trairatphisan, Panuwat; Pastor, Manuel

Evidence of erythropoiesis rather than direct genotoxicity causing micronucleus induction by a new protoporphyrinogen-oxidase inhibitor 新原卟啉原氧化酶抑制剂诱导微核的证据表明，其作用机制是促进红细胞生成而非直接基因毒性。

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

IF2.5

2025-10-01

PREAI

Honarvar, Naveed; Zander, Astrid; Shigano, Miyuki; Dony, Eva; Riffle, Brandy; Frericks, Markus; Seiser, Tobias; Landsiedel, Robert

Matched molecular pairs-driven read-across for the prediction of genotoxicity of plant protection product residues 基于匹配分子对的植物保护产品残留物遗传毒性预测读跨分析

Regulatory Toxicology and Pharmacology

IF3.5

2025-08-04

OAAI

S.J. Enoch; Z. Hasarova; M.T.D. Cronin; K. Bridgwood; S. Rao; A. Hueser; F.M. Kluxen; M. Frericks

An in silico protocol for endocrine activity assessment: Integrating predictions, experimental evidence, and expert reviews across estrogen, androgen, thyroid, and steroidogenesis modalities 一种用于内分泌活性评估的体外模拟方案：整合雌激素、雄激素、甲状腺和类固醇生成模式下的预测、实验证据和专家评审

Computational Toxicology

IF2.9

2025-06-25

PREAI

Candice Johnson; Sue Marty; Marlene Kim; Kevin Crofton; Alessandra Roncaglioni; Arianna Bassan; Tara Barton-Maclaren; Ana Domingues; Markus Frericks; Agnes Karmaus; Sunil Kulkarni; Elena Lo Piparo; Stephanie Melching-Kollmuss; Ray Tice; David Woolley; Kevin Cross

Validation of OECD QSAR Toolbox profilers for genotoxicity assessment of pesticides using the MultiCase genotoxicity database 利用MultiCase遗传毒性数据库对OECD QSAR Toolbox遗传毒性评估模型的验证

COMPUTATIONAL TOXICOLOGY

IF2.9

2025-06-01

PREAI

Kemeny, Monika; North, Colin M.; Kluxen, Felix M.; Frericks, Markus; Vukelic, Dragana; Cao, Sishuo; Saiakhov, Roustem; Girireddy, Mounika

The database makes the poison: How the selection of datasets in QSAR models impacts toxicant prediction of higher tier endpoints

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2024-08-01

OAAI

Burgoon, Lyle D.; Kluxen, Felix M.; Hueser, Anja; Frericks, Markus

Computational prediction of the metabolites of agrochemicals formed in rats 大鼠中形成的农用化学品代谢物的计算预测

SCIENCE OF THE TOTAL ENVIRONMENT

IF8

2023-10-01

OAAI

Scholz, Vincent-Alexander; Stork, Conrad; Frericks, Markus; Kirchmair, Johannes

A new approach methodology using kinetically-derived maximum dose levels in risk assessment - A case study with afidopyropen

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2023-08-01

PREAI

Loccisano, Anne E.; Freeman, Elaine; Doi, Adriana; Frericks, Markus; Fabian, Eric; Riffle, Brandy

Making in silico predictive models for toxicology FAIR 为毒理学博览会建立计算机预测模型

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2023-05-01

OAAI

Cronin, Mark T. D.; Belfield, Samuel J.; Briggs, Katharine A.; Enoch, Steven J.; Firman, James W.; Frericks, Markus; Garrard, Clare; Maccallum, Peter H.; Madden, Judith C.; Pastor, Manuel; Sanz, Ferran; Soininen, Inari; Sousoni, Despoina

Understanding and overcoming the technical challenges in using in silico predictions in regulatory decisions of complex toxicological endpoints-A pesticide perspective for regulatory toxicologists with a focus on machine learning models

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2023-01-01

OAAI

Burgoon, Lyle D.; Kluxen, Felix M.; Frericks, Markus

Sub-structure-based category formation for the prioritisation of genotoxicity hazard assessment for pesticide residues (part 2): Triazoles

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2022-10-01

OAAI

Enoch, S. J.; Hasarova, Z.; Cronin, M. T. D.; Frericks, M.

Sub-structure-based category formation for the prioritisation of genotoxicity hazard assessment for pesticide residues: Sulphonyl ureas

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2022-03-01

OAAI

Enoch, S. J.; Hasarova, Z.; Cronin, M. T. D.; Bridgwood, K.; Rao, S.; Kluxen, F. M.; Frericks, M.

Evaluating confidence in toxicity assessments based on experimental data and in silico predictions 根据实验数据和计算机预测评估毒性评估的置信度

COMPUTATIONAL TOXICOLOGY

IF2.9

2022-02-01

OAAI

Johnson, Candice; Anger, Lennart T.; Benigni, Romualdo; Bower, David; Bringezu, Frank; Crofton, Kevin M.; Cronin, Mark T. D.; Cross, Kevin P.; Dettwiler, Magdalena; Frericks, Markus; Melnikov, Fjodor; Miller, Scott; Roberts, David W.; Suarez-Rodrigez, Diana; Roncaglioni, Alessandra; Lo Piparo, Elena; Tice, Raymond R.; Zwickl, Craig; Myatt, Glenn J.

Ontogeny of renal, hepatic, and placental expression of ATP-binding cassette and solute carrier transporters in the rat and the rabbit

REPRODUCTIVE TOXICOLOGY

IF2.8

2022-01-01

OAAI

Weyrich, Anastasia; Frericks, Markus; Eichenlaub, Michael; Schneider, Steffen; Hofmann, Thomas; Van Cruchten, Steven; van Ravenzwaay, Bennard

In silico approaches in carcinogenicity hazard assessment: Current status and future needs

COMPUTATIONAL TOXICOLOGY

IF2.9

2021-11-01

OAAI

Tice, Raymond R.; Bassan, Arianna; Amberg, Alexander; Anger, Lennart T.; Beal, Marc A.; Bellion, Phillip; Benigni, Romualdo; Birmingham, Jeffrey; Brigo, Alessandro; Bringezu, Frank; Ceriani, Lidia; Crooks, Ian; Cross, Kevin; Elespuru, Rosalie; Faulkner, David M.; Fortin, Marie C.; Fowler, Paul; Frericks, Markus; Gerets, Helga H. J.; Jahnke, Gloria D.; Jones, David R.; Kruhlak, Naomi L.; Lo Piparo, Elena; Lopez-Belmonte, Juan; Luniwal, Amarjit; Luu, Alice; Madia, Federica; Manganelli, Serena; Manickam, Balasubramanian; Mestres, Jordi; Mihalchik-Burhans, Amy L.; Neilson, Louise; Pandiri, Arun; Pavan, Manuela; Rider, Cynthia V.; Rooney, John P.; Trejo-Martin, Alejandra; Watanabe-Sailor, Karen H.; White, Angela T.; Woolley, David; Myatt, Glenn J.

Afidopyropen: Challenges and impact of a toxicokinetic study designed to identify a point of inflection from dose-proportionality

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2021-08-01

PREAI

Loccisano, Anne E.; Freeman, Elaine; Riffle, Brandy; Doi, Adriana; Frericks, Markus; Fegert, Ivana; Fabian, Eric

Use of toxicokinetic data for afidopyropen to determine the dose levels in developmental toxicity studies

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2020-06-01

PREAI

Loccisano, Anne E.; Bus, James; Gollapudi, Bhaskar; Riffle, Brandy; Frericks, Markus; Fegert, Ivana; Fabian, Eric

Genetic toxicology in silico protocol 计算机协议中的遗传毒理学

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2019-10-01

OAAI

Hasselgren, Catrin; Ahlberg, Ernst; Akahori, Yumi; Amberg, Alexander; Anger, Lennart T.; Atienzar, Franck; Auerbach, Scott; Beilke, Lisa; Bellion, Phillip; Benigni, Romualdo; Bercu, Joel; Booth, Ewan D.; Bower, Dave; Brigo, Alessandro; Cammerer, Zoryana; Cronin, Mark T. D.; Crooks, Ian; Cross, Kevin P.; Custer, Laura; Dobo, Krista; Doktorova, Tatyana; Faulkner, David; Ford, Kevin A.; Fortin, Marie C.; Frericks, Markus; Gad-McDonald, Samantha E.; Gellatly, Nichola; Gerets, Helga; Gervais, Veronique; Glowienke, Susanne; Van Gompel, Jacky; Harvey, James S.; Hillegass, Jedd; Honma, Masamitsu; Hsieh, Jui-Hua; Hsu, Chia-Wen; Barton-Maclaren, Tara S.; Johnson, Candice; Jolly, Robert; Jones, David; Kemper, Ray; Kenyon, Michelle O.; Kruhlak, Naomi L.; Kulkarni, Sunil A.; Kuemmerer, Klaus; Leavitt, Penny; Masten, Scott; Miller, Scott; Moudgal, Chandrika; Muster, Wolfgang; Paulino, Alexandre; Lo Piparo, Elena; Powley, Mark; Quigley, Donald P.; Reddy, M. Vijayaray; Richarz, Andrea-Nicole; Schilter, Benoit; Snyder, Ronald D.; Stavitskaya, Lidiya; Stidl, Reinhard; Szabo, David T.; Teasdale, Andrew; Tice, Raymond R.; Trejo-Martin, Alejandra; Vuorinen, Anna; Wall, Brian A.; Watts, Pete; White, Angela T.; Wichard, Joerg; Witt, Kristine L.; Woolley, Adam; Woolley, David; Zwickl, Craig; Myatt, Glenn J.

Uterine adenocarcinoma adenocarcinoma in the rat induced by afidopyropen. An analysis of the lesion's induction, progression and its relevance to humans

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2018-06-01

PREAI

Van Cott, Andrew; Frericks, Markus; Hastings, Charles; Honarvar, Naveed; Flick, Burkhard; Fabian, Eric; van Ravenzwaay, Bennard

Promoter analysis of TCDD-inducible genes in a thymic epithelial cell line indicates the potential for cell-specific transcription factor crosstalk in the AhR response

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2008-10-01

PREAI

Frericks, Markus; Burgoon, Lyle D.; Zacharewski, Timothy R.; Esser, Charlotte

研究方向