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收藏分享 收藏 分享 收藏 分享 收藏 Phase 1 Trials of PNPLA3 siRNA in I148M Homozygous Patients with MAFLDPNPLA3 siRNA在I148M纯合子MAFLD患者中的1期试验
Fabbrini, Elisa; Rady, Brian; Koshkina, Anastasiya; Jeon, Jae Yoon; Ayyar, Vivaswath S.; Gargano, Cynthia; DiProspero, Nicholas; Wendel, Susan; Hegge, Julia; Hamilton, Holly; Ding, Zhi-Ming; Afrazi, Maria; Nicholas, Anthony; Pei, Tao; Nakano, Masayoshi; Ouchi, Shohei; Saito, Yuki; Yamashita, Aimi; Tamamura, Ryo; Salazar, Hernan; Shapiro, Craig; Yoshihara, Tatsuya; Yonemura, Takuma; Inoue, Satoshi; Matsuoka, Osamu; Erion, Mark; Pocai, Alessandro; Makimura, Hideo 分享 收藏 Long Term Follow-Up Study of a Randomized, Open-Label, Uncontrolled, Phase I/II Study to Assess the Safety and Immunogenicity of Intramuscular and Intradermal Doses of COVID-19 DNA Vaccine (AG0302-COVID19)一项随机、开放标签、非对照、I/II期研究的长期随访研究，以评估肌内和皮内剂量新型冠状病毒肺炎DNA疫苗 (AG0302-COVID19) 的安全性和免疫原性Nakagami, Hironori; Matsumoto, Tetsuya; Takazawa, Kenji; Sekino, Hisakuni; Matsuoka, Osamu; Inoue, Satoshi; Furuie, Hidetoshi; Morishita, Ryuichi 分享 收藏 \Safety/tolerability, efficacy and pharmacokinetics of 600-μg cotadutide in Japanese type 2 diabetes patients with a body mass index of 25 kg/m2 or higher: A phase I, randomized, double-blind, placebo-controlled studyAsano, Michiko; Sekikawa, Akiko; Sugeno, Masatoshi; Matsuoka, Osamu; Robertson, Darren; Hansen, Lars 分享 收藏 SCO-267, a GPR40 Full Agonist, Stimulates Islet and Gut Hormone Secretion and Improves Glycemic Control in Humans (vol 70, pg 2364, 2021)Nishizaki, Harunobu; Matsuoka, Osamu; Kagawa, Tomoya; Kobayashi, Akihiro; Watanabe, Masanori; Moritoh, Yusuke 分享 收藏 分享 收藏 分享 收藏 Immunogenicity and safety of high-dose quadrivalent influenza vaccine in Japanese adults ≥65 years of age: a randomized controlled clinical trial大剂量四价流感疫苗在 ≥ 65岁日本成人中的免疫原性和安全性: 一项随机对照临床试验Sanchez, Leilani; Matsuoka, Osamu; Inoue, Satoshi; Inoue, Takahiro; Meng, Ya; Nakama, Takahiro; Kato, Kumiko; Pandey, Aseem; Chang, Lee-Jah; Ando, Kiyotaka; Ito, Mild; Kawai, Makoto; Kawai, Mie; Miyashita, Yumi; Nakai, Nozomu; Otake, Sachiko; Yamaguchi, Izumi; Daito, Hisayoshi; Kanada, Shigeto; Owada, Yasuko; Takeya, Miyuki; Takeya, Yasushi; Yamamoto, Hiroko; Yamamoto, Koichi; Bonaparte, Kathryn; Boyle, Jacqueline; Broudic, Karine; De Bruijn, Iris; De Sousa, Jennifer; Emori, Toshihiro; Garg, Sanjay; Hayashi, Kaoru; Hollingsworth, Rosalind; Ida, Sanae; Ishii, Yasunori; Janosczyk, Helene; Kawaguchi, Osamu; Khoury, Rawia; Kobayashi, Yuko; Landolfi, Victoria; Marshall, Erik; Matsuzaki, Minako; Menard, Lisa; Miyazawa, Rina; Nishimori, Shoko; Ohshima, Shinobu; Ohtsuki, Miyako; Oka, Hayato; Okada, Keiko; Otsuka, Akiko; Patskan, Viktor; Pekala, David; Quinn, Therese; Ruparel, Renuka; Samson, Sandrine; Shinozaki, Makoto; Sirisuphmitr, Nuchra; Sodeyama, Takashi; Takebuchi, Kazushi; Terashima, Romi; Urso, Maxime; Yoshida, Arika 分享 收藏 Safety and immunogenicity of Clostridium difficile toxoid vaccine in Japanese adultsMatsuoka, Osamu; Patel, Dhaval M.; Sasaki, Shin; Oka, Hayato; Sasaki, Toru; Pietrobon, Patricia J.; Laot, Thelma; Bouckenooghe, Alain; Menezes, Josemund; de Bruyn, Guy 分享 收藏 Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive - Results From a Randomized, Placebo-Controlled, Dose-Ranging StudyYokote, Koutaro; Kanada, Shigeto; Matsuoka, Osamu; Sekino, Hisakuni; Imai, Keiji; Tabira, Junichi; Matsuoka, Nobushige; Chaudhuri, Sandip; Teramoto, Tamio 分享 收藏 分享 收藏 Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: a phase II multicentre, randomized, double-blind, placebo-controlled trial在血糖控制不充分的日本患者中，达格列净单药治疗2型糖尿病的疗效和安全性: 一项II期多中心，随机，双盲，安慰剂对照试验Kaku, K.; Inoue, S.; Matsuoka, O.; Kiyosue, A.; Azuma, H.; Hayashi, N.; Tokudome, T.; Langkilde, A. M.; Parikh, S. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Arterial stiffness independently predicts cardiovascular events in an elderly community -: Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) studyMatsuoka, O; Otsuka, K; Murakami, S; Hotta, N; Yamanaka, G; Kubo, Y; Yamanaka, T; Shinagawa, M; Nunoda, S; Nishimura, Y; Shibata, K; Saitoh, H; Nishinaga, M; Ishine, M; Wada, T; Okumiya, K; Matsubayashi, K; Yano, S; Ichihara, K; Cornélissen, G; Halberg, F; Ozawa, T 分享 收藏 
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