未登录 Alternating gemcitabine plus nab-paclitaxel and gemcitabine alone versus continuous gemcitabine plus nab-paclitaxel after induction treatment of metastatic pancreatic cancer (ALPACA): a multicentre, randomised, open-label, phase 2 trial Dorman, Klara; Boeck, Stefan; Caca, Karel; Reichert, Maximilian; Ettrich, Thomas J.; Oettle, Helmut; Waidmann, Oliver; Modest, Dominik P.; Mueller, Lothar; Michl, Patrick; Kanzler, Stephan; Pink, Daniel; Reinacher-Schick, Anke; Geissler, Michael; Pelz, Henning; Kunzmann, Volker; Held, Swantje; Schichtl, Thomas; Heinemann, Volker; Kullmann, Frank 分享 收藏
KRT81 and HNF1A expression in pancreatic ductal adenocarcinoma: investigation of predictive and prognostic value of immunohistochemistry-based subtyping Rao, Jia; Sinn, Marianne; Pelzer, Uwe; Riess, Hanno; Oettle, Helmut; Demir, Ihsan E.; Friess, Helmut; Jaeger, Carsten; Steiger, Katja; Muckenhuber, Alexander 分享 收藏
Regional hyperthermia with cisplatin added to gemcitabine versus gemcitabine in patients with resected pancreatic ductal adenocarcinoma: The HEAT randomised clinical trial 在切除的胰腺导管腺癌患者中，吉西他滨与吉西他滨联合顺铂的局部热疗: HEAT随机临床试验 Issels, Rolf D.; Boeck, Stefan; Pelzer, Uwe; Mansmann, Ulrich; Ghadjar, Pirus; Lindner, Lars H.; Albertsmeier, Markus; Angele, Martin K.; Schmidt, Michael; Xu, Yujun; Bahra, Marcus; Pratschke, Johann; Schoenberg, Michael; Thasler, Wolfgang E.; Salat, Christoph; Stoetzer, Oliver J.; Knoefel, Wolfram T.; Graf, Dirk; Wessalowski, Rudiger; Keitel-Anselmino, Verena; Koenigsrainer, Alfred; Bitzer, Michael; Zips, Daniel; Bamberg, Michael; Fietkau, Rainer; Ott, Oliver; Kawecki, Maciej; Wyrwicz, Lucian; Rutkowski, Piotr; Rentsch, Markus; Ababei, Juliana; Reichardt, Peter; Rigamonti, Marco; Weber, Bernhard; Abdel-Rahman, Sultan; Tschoep-Lechner, Katharina; Jauch, Karl-Walter; Bruns, Christiane J.; Oettle, Helmut; von Bergwelt-Baildon, Michael; Heinemann, Volker; Werner, Jens 分享 收藏
Dual Targeting of the EGFR/HER2 Pathway in Combination with Systemic Chemotherapy in Refractory Pancreatic Cancer-The CONKO-008 Phase I Investigation Striefler, Jana K.; Stieler, Jens M.; Neumann, Christopher C. M.; Geisel, Dominik; Ghadjar, Pirus; Sinn, Marianne; Malinka, Thomas; Pratschke, Johann; Stintzing, Sebastian; Oettle, Helmut; Riess, Hanno; Pelzer, Uwe 分享 收藏
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression 颗粒蛋白前体通过调节MHCI表达介导胰腺导管腺癌的免疫逃避 Cheung, Phyllis F.; Yang, JiaJin; Fang, Rui; Borgers, Arianna; Krengel, Kirsten; Stoffel, Anne; Althoff, Kristina; Yip, Chi Wai; Siu, Elaine H. L.; Ng, Linda W. C.; Lang, Karl S.; Cham, Lamin B.; Engel, Daniel R.; Soun, Camille; Cima, Igor; Scheffler, Bjoern; Striefler, Jana K.; Sinn, Marianne; Bahra, Marcus; Pelzer, Uwe; Oettle, Helmut; Markus, Peter; Smeets, Esther M. M.; Aarntzen, Erik H. J. G.; Savvatakis, Konstantinos; Liffers, Sven-Thorsten; Lueong, Smiths S.; Neander, Christian; Bazarna, Anna; Zhang, Xin; Paschen, Annette; Crawford, Howard C.; Chan, Anthony W. H.; Cheung, Siu Tim; Siveke, Jens T. 分享 收藏
Mucin-1 Protein Is a Prognostic Marker for Pancreatic Ductal Adenocarcinoma: Results From the CONKO-001 Study Striefler, Jana Kaethe; Riess, Hanno; Lohneis, Philipp; Bischoff, Sven; Kurreck, Annika; Modest, Dominik Paul; Bahra, Marcus; Oettle, Helmut; Sinn, Marianne; Blaeker, Henrik; Denkert, Carsten; Stintzing, Sebastian; Sinn, Bruno Valentin; Pelzer, Uwe 分享 收藏
Original Research Impact of completeness of adjuvant gemcitabine, relapse pattern, and subsequent therapy on outcome of patients with resected pancreatic ductal adenocarcinoma-A pooled analysis of CONKO-001, CONKO-005, and CONKO-006 trials Kurreck, Annika; Weckwerth, Johanna; Modest, Dominik P.; Striefler, Jana K.; Bahra, Marcus; Bischoff, Sven; Pelzer, Uwe; Oettle, Helmut; Kruger, Stephan; Riess, Hanno; Sinn, Marianne 分享 收藏
Outcomes from the Asian region of the phase III APACT trial of adjuvant nab-paclitaxel plus gemcitabine (nab-P/G) vs gemcitabine (G) alone for patients (pts) with resected pancreatic cancer (PC) Park, J. Oh; Li, C-P.; Chang, H-M.; Shan, Y. S.; Bendell, J.; Garlipp, B.; Hatoum, H.; Laquente Saez, B.; Salminen, T.; Oettle, H.; Kocsis, J.; Lopez, R.; Dowden, S.; Karthaus, M.; Lu, B.; McGovern, D.; Banerjee, S.; Tempero, M.; Oh, D-Y. 分享 收藏
CONKO-006: A randomised double-blinded phase IIb-study of additive therapy with gemcitabine plus sorafenib/placebo in patients with R1 resection of pancreatic cancer - Final results Sinn, M.; Liersch, T.; Riess, H.; Gellert, K.; Stuebs, P.; Waldschmidt, D.; Lammert, F.; Maschmeyer, G.; Bechstein, W.; Bitzer, M.; Denzlinger, C.; Hofheinz, R.; Lindig, U.; Ghadimi, M.; Hinke, A.; Striefler, J. K.; Pelzer, U.; Bischoff, S.; Bahra, M.; Oettle, H. 分享 收藏
TP53 Mutations Predict Sensitivity to Adjuvant Gemcitabine in Patients with Pancreatic Ductal Adenocarcinoma: Next-Generation Sequencing Results from the CONKO-001 Trial Sinn, Marianne; Sinn, Bruno, V; Treue, Denise; Keilholz, Ulrich; Damm, Frederik; Schmuck, Rosa; Lohneis, Philipp; Klauschen, Frederick; Striefler, Jana K.; Bahra, Marcus; Blaeker, Hendrik; Bischoff, Sven; Pelzer, Uwe; Oettle, Helmut; Riess, Hanno; Budczies, Jan; Denkert, Carsten 分享 收藏
Consensus in determining the resectability of locally progressed pancreatic ductal adenocarcinoma - results of the Conko-007 multicenter trial 确定局部进展性胰腺导管腺癌可切除性的共识-Conko-007多中心试验的结果 Wittel, U. A.; Lubgan, D.; Ghadimi, M.; Belyaev, O.; Uhl, W.; Bechstein, W. O.; Gruetzmann, R.; Hohenberger, W. M.; Schmid, A.; Jacobasch, L.; Croner, R. S.; Reinacher-Schick, A.; Hopt, U. T.; Pirkl, A.; Oettle, H.; Fietkau, R.; Golcher, H. 分享 收藏
Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer Melisi, Davide; Garcia-Carbonero, Rocio; Macarulla, Teresa; Pezet, Denis; Deplanque, Gael; Fuchs, Martin; Trojan, Jorg; Oettle, Helmut; Kozloff, Mark; Cleverly, Ann; Smith, Claire; Estrem, Shawn T.; Gueorguieva, Ivelina; Lahn, Michael M. F.; Blunt, Al; Benhadji, Karim A.; Tabernero, Josep 分享 收藏
Tumour buds determine prognosis in resected pancreatic ductal adenocarcinoma Lohneis, Philipp; Sinn, Marianne; Klein, Fritz; Bischoff, Sven; Striefler, Jana K.; Wislocka, Lilianna; Sinn, Bruno V.; Pelzer, Uwe; Oettle, Helmut; Riess, Hanno; Denkert, Carsten; Blaeker, Hendrik; Juehling, Anja 分享 收藏
SPARC expression in resected pancreatic cancer patients treated with Gemcitabine: results from the CONKO-001 study (vol 25, pg 1025, 2014) Sinn, M.; Sinn, B. V.; Striefler, J. K.; Lindner, J. L.; Stieler, J. M.; Lohneis, P.; Bischoff, S.; Blaker, H.; Pelzer, U.; Bahra, M.; Dietel, M.; Dorken, B.; Oettle, H.; Riess, H.; Denkert, C. 分享 收藏
Cytotoxic tumour-infiltrating T lymphocytes influence outcome in resected pancreatic ductal adenocarcinoma Lohneis, Philipp; Sinn, Marianne; Bischoff, Sven; Juehling, Anja; Pelzer, Uwe; Wislocka, Lilianna; Bahra, Marcus; Sinn, Bruno V.; Denkert, Carsten; Oettle, Helmut; Blaeker, Hendrik; Riess, Hanno; Joehrens, Korinna; Striefler, Jana K. 分享 收藏
Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells 小鼠胰腺肿瘤切除后给予吉西他滨诱导自然杀伤细胞介导的抗肿瘤免疫反应 Guerlevik, Engin; Fleischmann-Mundt, Bettina; Brooks, Jennifer; Demir, Ihsan Ekin; Steiger, Katja; Ribback, Silvia; Yevsa, Tetyana; Woller, Norman; Kloos, Arnold; Ostroumov, Dmitrij; Armbrecht, Nina; Manns, Michael P.; Dombrowski, Frank; Saborowski, Michael; Kleine, Moritz; Wirth, Thomas C.; Oettle, Helmut; Ceyhan, Gueralp O.; Esposito, Irene; Calvisi, Diego F.; Kubicka, Stefan; Kuehnel, Florian 分享 收藏
A randomized phase II, double-blind study to evaluate the efficacy and safety of galunisertib plus gemcitabine (GG) or gemcitabine plus placebo (GP) in patients with unresectable pancreatic cancer (PC) Melisi, Davide; Garcia-Carbonero, Rocio; Macarulla, Teresa; Pezet, Denis; Deplanque, Gael; Fuchs, Martin; Trojan, Joerg; Oettle, Helmut; Kozloff, Mark; Cleverly, Ann; Gueorguieva, Ivelina; Desaiah, Durisala; Lahn, Michael M.; Al Blunt; Benhadji, Karim A.; Tabernero, Josep 分享 收藏
Human equilibrative nucleoside transporter 1 expression analysed by the clone SP 120 rabbit antibody is not predictive in patients with pancreatic cancer treated with adjuvant gemcitabine - Results from the CONKO-001 trial Sinn, M.; Riess, H.; Sinn, B. V.; Stieler, J. M.; Pelzer, U.; Striefler, J. K.; Oettle, H.; Bahra, M.; Denkert, C.; Blaeker, H.; Lohneis, P. 分享 收藏
α-Smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study Sinn, M.; Denkert, C.; Striefler, J. K.; Pelzer, U.; Stieler, J. M.; Bahra, M.; Lohneis, P.; Doerken, B.; Oettle, H.; Riess, H.; Sinn, B. V. 分享 收藏
SPARC expression in resected pancreatic cancer patients treated with gemcitabine: results from the CONKO-001 study Sinn, M.; Sinn, B. V.; Striefler, J. K.; Lindner, J. L.; Stieler, J. M.; Lohneis, P.; Bischoff, S.; Blaeker, H.; Pelzer, U.; Bahra, M.; Dietel, M.; Doerken, B.; Oettle, H.; Riess, H.; Denkert, C. 分享 收藏
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