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J

Jim J. Hagan

GlaxoSmithKline

55H指数
163论文数
1.0W被引数
收录论文 49
发表时间
Drug repositioning for Alzheimer's disease
err2012-11-05
err247
PREAI
errCorbett, Anne; Pickett, James; Burns, Alistair; Corcoran, Jonathan; Dunnett, Stephen B.; Edison, Paul; Hagan, Jim J.; Holmes, Clive; Jones, Emma; Katona, Cornelius; Kearns, Ian; Kehoe, Patrick; Mudher, Amrit; Passmore, Anthony; Shepherd, Nicola; Walsh, Frank; Ballard, Clive
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In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics
err2010-02-01
err11
PREAI
errDawson, Lee A.; Langmead, Christopher J.; Dada, Adeshola; Watson, Jeannette M.; Wu, Zining; de la Flor, Raul; Jones, Gareth A.; Cluderay, Jane E.; Southam, Eric; Murkitt, Graham S.; Hill, Mark D.; Jones, Declan N. C.; Davies, Ceri H.; Hagan, Jim J.; Smith, Paul W.
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Chronic fluoxetine differentially modulates the hippocampal microtubular and serotonergic system in grouped and isolation reared rats
err2009-11-01
err28
PREAI
errBianchi, Massimiliano; Fone, Kevin C. F.; Shah, Ajit J.; Atkins, Alan R.; Dawson, Lee A.; Heidbreder, Christian A.; Hagan, Jim J.; Marsden, Charles A.
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Altered M1 Muscarinic Acetylcholine Receptor (CHRM1)-Gαq/11 Coupling in a Schizophrenia Endophenotype
err2009-04-29
err46
errOAAI
errSalah-Uddin, Hasib; Scarr, Elizabeth; Pavey, Geoffrey; Harris, Kriss; Hagan, Jim J.; Dean, Brian; Challiss, R. A. John; Watson, Jeannette M.
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Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function
err2009-03-03
err170
PREAI
errMaycox, P. R.; Kelly, F.; Taylor, A.; Bates, S.; Reid, J.; Logendra, R.; Barnes, M. R.; Larminie, C.; Jones, N.; Lennon, M.; Davies, C.; Hagan, J. J.; Scorer, C. A.; Angelinetta, C.; Akbar, T.; Hirsch, S.; Mortimer, A. M.; Barnes, T. R. E.; de Belleroche, J.
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Functional characterisation of the human cloned 5-HT7 receptor (long form);: antagonist profile of SB-258719
err2009-02-11
err121
errOAAI
errThomas, DR; Gittins, SA; Collin, LL; Middlemiss, DN; Riley, G; Hagan, J; Gloger, I; Ellis, CE; Forbes, IT; Brown, AM
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Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1
err2009-01-29
err119
errOAAI
errLangmead, C. J.; Austin, N. E.; Branch, C. L.; Brown, J. T.; Buchanan, K. A.; Davies, C. H.; Forbes, I. T.; Fry, V. A. H.; Hagan, J. J.; Herdon, H. J.; Jones, G. A.; Jeggo, R.; Kew, J. N. C.; Mazzali, A.; Melarange, R.; Patel, N.; Pardoe, J.; Randall, A. D.; Roberts, C.; Roopun, A.; Starr, K. R.; Teriakidis, A.; Wood, M. D.; Whittington, M.; Wu, Z.; Watson, J.
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[3H]-SB-269970 -: A selective antagonist radioligand for 5-HT7 receptors[3h]-SB-269970 -: 5-HT7受体的选择性拮抗剂放射性配体
err2009-01-29
err71
errOAAI
errThomas, DR; Atkinson, PJ; Ho, M; Bromidge, SM; Lovell, PJ; Villani, AJ; Hagan, JJ; Middlemiss, DN; Price, GW
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SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats新型选择性5-HT7受体拮抗剂SB-656104-A调节大鼠REM睡眠
err2009-01-29
err134
errOAAI
errThomas, DR; Melotto, S; Massagrande, M; Gribble, AD; Jeffrey, P; Stevens, AJ; Deeks, NJ; Eddershaw, PJ; Fenwick, SH; Riley, G; Stean, T; Scott, CM; Hill, MJ; Middlemiss, DN; Hagan, JJ; Price, GW; Forbes, IT
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Characterization of SB-269970-A, a selective 5-HT7 receptor antagonist选择性5-HT7受体拮抗剂SB-269970-A的表征
err2009-01-29
err293
errOAAI
errHagan, JJ; Price, GW; Jeffrey, P; Deeks, NJ; Stean, T; Piper, D; Smith, MI; Upton, N; Medhurst, AD; Middlemiss, DN; Riley, GJ; Lovell, PJ; Bromidge, SM; Thomas, DR
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Pharmacological assessment of M1 muscarinic acetylcholine receptor-Gq/11 protein coupling in membranes prepared from postmortem human brain tissue
err2008-06-01
err21
PREAI
errSalah-Uddin, Hasib; Thomas, David R.; Davies, Ceri H.; Hagan, Jim J.; Wood, Martyn D.; Watson, Jeannette M.; Challiss, R. A. John
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1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines:: A series of potent and selective dopamine D3 receptor antagonists
err2007-09-15
err88
PREAI
errMicheli, Fabrizio; Bonanomi, Giorgio; Blaney, Frank E.; Braggio, Simone; Capelli, Anna Maria; Checchia, Anna; Curcuruto, Ornella; Damiani, Federica; Di Fabio, Romano; Donati, Daniele; Gentile, Gabriella; Gribble, Andy; Hamprecht, Dieter; Tedesco, Giovanna; Terreni, Silvia; Tarsi, Luca; Lightfoot, Andrew; Stemp, Geoff; MacDonald, Gregor; Smith, Alex; Pecoraro, Michela; Petrone, Marcella; Perini, Ornella; Piner, Jacqui; Rossi, Tino; Worby, Angela; Pilla, Maria; Valerio, Enzo; Griffante, Cristiana; Mugnaini, Manolo; Wood, Martyn; Scott, Claire; Andreoli, Michela; Lacroix, Laurent; Schwarz, Adam; Gozzi, Alessandro; Bifone, Angelo; Ashby, Charles R., Jr.; Hagan, Jim J.; Heidbreder, Christian
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In vitro and in vivo characterization of the non-peptide NK3 receptor antagonist SB-223412 (talnetant):: Potential therapeutic utility in the treatment of schizophrenia
err2007-08-29
err39
errOAAI
errDawson, Lee A.; Cato, Katherine J.; Scott, Claire; Watson, Jeannette M.; Wood, Martyn D.; Foxton, Richard; de la Flor, Raul; Jones, Gareth A.; Kew, James N. C.; Cluderay, Jane E.; Southam, Eric; Murkitt, Graham S.; Gartlon, Jane; Pemberton, Darrel J.; Jones, Declan N. C.; Davies, Ceri H.; Hagan, Jim
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SB-649915-B, a novel 5-HT1A/B Autoreceptor antagonist and serotonin Reuptake inhibitor, is Anxiolytic and displays fast onset activity in the rat high light social interaction test
err2007-03-14
err49
errOAAI
errStarr, Kathryn R.; Price, Gary W.; Watson, Jeannette M.; Atkinson, Peter J.; Arban, Roberto; Melotto, Sergio; Dawson, Lee A.; Hagan, Jim J.; Upton, Neil; Duxon, Mark S.
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5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats
err2005-04-21
err111
PREAI
errHatcher, PD; Brown, VJ; Tait, DS; Bate, S; Overend, P; Hagan, JJ; Jones, DNC
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Localisation of NMU1R and NMU2R in human and rat central nervous system and effects of neuromedin-U following central administration in rats
err2004-06-16
err47
PREAI
errGartlon, J; Szekeres, P; Pullen, M; Sarau, HM; Aiyar, N; Shabon, U; Michalovich, D; Steplewski, K; Ellis, C; Elshourbagy, N; Duxon, M; Ashmeade, TE; Harrison, DC; Murdock, P; Wilson, S; Ennaceur, A; Atkins, A; Heidbreder, C; Hagan, JJ; Hunter, AJ; Jones, DNC
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Urotensin-II, a neuropeptide ligand for GPR14, induces c-fos in the rat brain
err2004-06-01
err10
PREAI
errGartlon, JE; Ashmeade, T; Duxon, M; Hagan, JJ; Jones, DNC
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