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Two-Dimensional and Point Shear-Wave Elastography to Predict Esophageal Varices and Clinically Significant Portal Hypertension in Patients with Chronic Liver Disease 二维和点剪切波弹性成像预测慢性肝病患者食管静脉曲张和临床意义的门脉高压 Heilani, Myriam W.; Bolender, Max; Muecke, Victoria T.; Schwarzkopf, Katharina M.; Kubesch-Gruen, Alica; Abedin, Nada; Dultz, Georg; Zeuzem, Stefan; Welsch, Christoph; Friedrich-Rust, Mireen; Bojunga, Joerg; Herrmann, Eva; Muecke, Marcus M. 分享 收藏
Sustained virologic response in patients with cirrhosis from chronic hepatitis C leads to sustained and long-term improvement of health-related quality of life, fatigue, and work productivity Younossi, Zobair; Stepanova, Maria; Racilla, Andrei; Jacobson, Ira; Muir, Andrew; Zeuzem, Stefan; Lawitz, Eric; Pol, Stanislas; Gaggar, Anuj; Myers, Robert; Younossi, Issah; Nader, Fatema 分享 收藏
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses Michels, Birgitta E.; Mosa, Mohammed H.; Grebbin, Britta M.; Yepes, Diego; Darvishi, Tahmineh; Hausmann, Johannes; Urlaub, Henning; Zeuzem, Stefan; Kvasnicka, Hans M.; Oellerich, Thomas; Farin, Henner F. 分享 收藏
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Glecaprevir/pibrentasvir in patients with hepatitis C and prior treatment experience: an integrated phase II/III analysis Poordad, F.; Zeuzem, S.; Asatryan, A.; Foster, G.; Gane, E.; Wyles, D.; Stanislas, P.; Ferret, M. B.; Kwo, P.; Asselah, T.; Kowdley, K. V.; Hezode, C.; Agarwal, K.; Wang, S.; Zadeikis, N.; Ng, I. C.; Pilot-Matias, T.; Lei, Y.; Kort, J.; Lin, C. -W.; Mensa, F. 分享 收藏
Sofosbuvir-Based Direct-Acting Antiviral Therapies for HCV in People Receiving Opioid Substitution Therapy: An Analysis of Phase 3 Studies Grebely, Jason; Feld, Jordan J.; Wyles, David; Sulkowski, Mark; Ni, Liyun; Llewellyn, Joe; Mir, Heshaam M.; Sajed, Nika; Stamm, Luisa M.; Hyland, Robert H.; McNally, John; Brainard, Diana M.; Jacobson, Ira; Zeuzem, Stefan; Bourliere, Marc; Foster, Graham; Afdhal, Nezam; Dore, Gregory J. 分享 收藏
Glecaprevir-Pibrentasvir for 8 or 12 Weeks in HCV Genotype 1 or 3 Infection Zeuzem, S.; Foster, G. R.; Wang, S.; Asatryan, A.; Gane, E.; Feld, J. J.; Asselah, T.; Bourliere, M.; Ruane, P. J.; Wedemeyer, H.; Pol, S.; Flisiak, R.; Poordad, F.; Chuang, W. -L.; Stedman, C. A.; Flamm, S.; Kwo, P.; Dore, G. J.; Sepulveda-Arzola, G.; Roberts, S. K.; Soto-Malave, R.; Kaita, K.; Puoti, M.; Vierling, J.; Tam, E.; Vargas, H. E.; Bruck, R.; Fuster, F.; Paik, S. -W.; Felizarta, F.; Kort, J.; Fu, B.; Liu, R.; Ng, T. I.; Pilot-Matias, T.; Lin, C. -W.; Trinh, R.; Mensa, F. J. 分享 收藏
Safety and efficacy of an 8-week regimen of grazoprevir plus ruzasvir plus uprifosbuvir compared with grazoprevir plus elbasvir plus uprifosbuvir in participants without cirrhosis infected with hepatitis C virus genotypes 1, 2, or 3 (C-CREST-1 and C-CREST-2, part A): two randomised, phase 2, open-label trials Gane, Edward J.; Pianko, Stephen; Roberts, Stuart K.; Thompson, Alexander J.; Zeuzem, Stefan; Zuckerman, Eli; Ben-Ari, Ziv; Foster, Graham R.; Agarwal, Kosh; Laursen, Alex L.; Gerstoft, Jan; Gao, Wei; Huang, Hsueh-Cheng; Fitzgerald, Brian; Fernsler, Doreen; Li, Jerry J.; Grandhi, Anjana; Liu, Hong; Su, Feng-Hsiu; Wan, Shuyan; Zeng, Zhen; Chen, Huei-Ling; Dutko, Frank J.; Nguyen, Bach-Yen T.; Wahl, Janice; Robertson, Michael N.; Barr, Eliav; Yeh, Wendy W.; Plank, Rebeca M.; Butterton, Joan R.; Esteban, Rafael 分享 收藏
SOF/VEL/VOX RESULTS IN HIGH SVR12 RATES WHEN ADMINISTERED FOR 12 WEEKS IN DAA-EXPERIENCED PATIENTS OR FOR 8 WEEKS IN DAA-NAIVE PATIENTS: AN INTEGRATED ANALYSIS OF THE POLARIS-1, POLARIS-2, POLARIS-3 AND POLARIS-4 STUDIES Flamm, Steven L.; Roberts, Stuart; Cooper, Curtis L.; Lawitz, Eric; Reddy, K. Rajender; Thompson, Alexander; Zeuzem, Stefan; Jacobson, Ira M.; Ruane, Peter J.; Mehta, Swarup S.; Hyland, Robert H.; Stamm, Luisa; Han, Lingling; Brainard, Diana; Brau, Norbert; Asselah, Tarik; Willems, Bernard; Bourliere, Marc; Foster, Graham R.; Gane, Edward; Manns, Michael; Gordon, Stuart C.; Kowdley, Kris V. 分享 收藏
SOFOSBUVIR/VELPATASVIR (SOF/VEL) WITH OR WITHOUT VOXILAPREVIR (VOX) IS ASSOCIATED WITH EXCELLENT EFFICACY AND SIGNIFICANT IMPROVEMENTS OF PATIENT-REPORTED OUTCOMES (PROS) DURING TREATMENT AND AFTER ACHIEVING SUSTAINED VIROLOGIC RESPONSE (SVR) Younossi, Zobair M.; Stepanova, Maria; Jacobson, Ira M.; Zeuzem, Stefan; Bourliere, Marc; Foster, Graham R.; Roberts, Stuart; Asselah, Tarik; Thompson, Alexander; Gane, Edward; Willems, Bernard; Lawitz, Eric; Gordon, Stuart C.; Manns, Michael; Reddy, K. Rajender; Cooper, Curtis L.; Flamm, Steven L.; Kowdley, Kris V.; Hunt, Sharon 分享 收藏
THE SAFETY AND TOLERABILITY OF SOF/VEL/VOX FOR 8 OR 12 WEEKS IN >1,000 PATIENTS TREATED IN THE POLARIS-1, POLARIS-2, POLARIS-3, AND POLARIS-4 STUDIES: AN INTEGRATED ANALYSIS Gordon, Stuart C.; Gane, Edward; Willems, Bernard; Roberts, Stuart A.; Flamm, Steven L.; Bourliere, Marc; Asselah, Tarik; Alric, Laurent; Letterio, Cathleen; Llewellyn, Joe; Hyland, Robert H.; Stamm, Luisa; Huang, K. C.; Brainard, Diana; Khalili, Mandana; Foster, Graham R.; Manns, Michael; Reddy, K. Rajender; Zeuzem, Stefan; Jacobson, Ira M.; Cooper, Curtis L.; Thompson, Alexander; Kowdley, Kris V.; Lawitz, Eric 分享 收藏
SOFOSBUVIR-BASED ALL-ORAL REGIMENS FOR PATIENTS WITH CHRONIC HEPATITIS C GENOTYPE 2 INFECTION: INTEGRATED ANALYSIS OF ELEVEN CLINICAL STUDIES Ho, Samuel B.; Han, Kwang Hyub; Ahn, Sang Hoon; Lim, Young-Suk; Kao, Jia-Horng; Chuang, Wan-Long; Omata, Masao; Moon, Scott; Crans, Gerald; Llewellyn, Joe; Natha, Macky; De-Oertel, Shampa; Brainard, Diana; Foster, Graham R.; Gane, Edward; Lawitz, Eric; Zeuzem, Stefan; Jacobson, Ira M. 分享 收藏
Sofosbuvir and Velpatasvir Combination Improves Patient-reported Outcomes for Patients With HCV Infection, Without or With Compensated or Decompensated Cirrhosis Younossi, Zobair M.; Stepanova, Maria; Feld, Jordan; Zeuzem, Stefan; Sulkowski, Mark; Foster, Graham R.; Mangia, Alessandra; Charlton, Michael; O'Leary, Jacqueline G.; Curry, Michael P.; Nader, Fatema; Henry, Linda; Hunt, Sharon 分享 收藏
Sofosbuvir-based all-oral regimens for patients with chronic hepatitis C genotype 2 infection: integrated analysis of eleven clinical studies Zeuzem, S.; Han, K. -H.; Ahn, S. -H.; Lim, Y. -S.; Kao, J. -H.; Chuang, W. -L.; Omata, M.; Abramov, F.; Crans, G.; Llewellyn, J.; Natha, M.; De-Oertel, S.; Brainard, D.; Foster, G. R.; Gane, E. J.; Lawitz, E.; Ho, S. B.; Jacobson, I. M. 分享 收藏
High efficacy is accompanied with substantial gains in patient reported outcomes in cirrhotic patients with chronic hepatitis C treated with sofosbuvir (SOF), velpatasvir with or without voxilaprevir (VOX): data from POLARIS 1, 2, 3 and 4 Younossi, Z. M.; Stepanova, M.; Jacobson, I.; Zeuzem, S.; Bourliere, M.; Foster, G.; Roberts, S.; Asselah, T.; Thompson, A.; Gane, E.; Willems, B.; Lawitz, E.; Gordon, S.; Mann, M.; Reddy, K. R.; Cooper, C.; Flamm, S.; Kowdley, K.; Hunt, S. 分享 收藏
SOF/VEL/VOX results in high SVR12 rates when administered for 12 weeks in DAA-experienced patients or for 8 Weeks in DAA-naive patients: an integrated analysis of the POLARIS-1, POLARIS-2, POLARIS-3 and POLARIS-4 studies Roberts, S. K.; Cooper, C. L.; Lawitz, E.; Reddy, K. R.; Thompson, A. J.; Zeuzem, S.; Jacobson, I. M.; Ruane, P.; Hyland, R. H.; Stamm, L. M.; Han, L.; Brainard, D. M.; Brau, N.; Asselah, T.; Willems, B. E.; Flamm, S.; Bourliere, M.; Foster, G. R.; Gane, E. J.; Manns, M.; Gordon, S. C.; Kowdley, K. 分享 收藏
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Efficacy and Safety of Sofosbuvir/Velpatasvir in Patients With Chronic Hepatitis C Virus Infection Receiving Opioid Substitution Therapy: Analysis of Phase 3 ASTRAL Trials Grebely, Jason; Dore, Gregory J.; Zeuzem, Stefan; Aspinall, Richard J.; Fox, Raymond; Han, Lingling; McNally, John; Osinusi, Anu; Brainard, Diana M.; Subramanian, G. Mani; Natha, Macky; Foster, Graham R.; Mangia, Alessandra; Sulkowski, Mark; Feld, Jordan J. 分享 收藏
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