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Brain neurokinin-1 receptor availability in never-medicated patients with major depression - A pilot study Nyman, Mikko; Eskola, Olli; Kajander, Jaana; Jokinen, Riitta; Penttinen, Jukka; Karjalainen, Tomi; Nummenmaa, Lauri; Hirvonen, Jussi; Burns, Donald; Hargreaves, Richard; Solin, Olof; Hietala, Jarmo 分享 收藏
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Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys Tannenbaum, Pamela L.; Tye, Spencer J.; Stevens, Joanne; Gotter, Anthony L.; Fox, Steven V.; Savitz, Alan T.; Coleman, Paul J.; Uslaner, Jason M.; Kuduk, Scott D.; Hargreaves, Richard; Winrow, Christopher J.; Renger, John J. 分享 收藏
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11C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists Van Laere, Koenraad J.; Sanabria-Bohorquez, Sandra M.; Mozley, David P.; Burns, Donald H.; Hamill, Terence G.; Van Hecken, Anne; De Lepeleire, Inge; Koole, Michel; Bormans, Guy; de Hoon, Jan; Depre, Marleen; Cerchio, Kristine; Plalcza, John; Han, Lingling; Renger, John; Hargreaves, Richard J.; Iannone, Robert 分享 收藏
In Vivo Quantification of Calcitonin Gene-Related Peptide Receptor Occupancy by Telcagepant in Rhesus Monkey and Human Brain Using the Positron Emission Tomography Tracer [11C]MK-4232 Hostetler, Eric D.; Joshi, Aniket D.; Sanabria-Bohorquez, Sandra; Fan, Hong; Zeng, Zhizhen; Purcell, Mona; Gantert, Liza; Riffel, Kerry; Williams, Mangay; O'Malley, Stacey; Miller, Patricia; Selnick, Harold G.; Gallicchio, Steven N.; Bell, Ian M.; Salvatore, Christopher A.; Kane, Stefanie A.; Li, Chi-Chung; Hargreaves, Richard J.; de Groot, Tjibbe; Bormans, Guy; Van Hecken, Anne; Derdelinckx, Inge; de Hoon, Jan; Reynders, Tom; Declercq, Ruben; De Lepeleire, Inge; Kennedy, W. P.; Blanchard, Rebecca; Marcantonio, Eugene E.; Sur, Cyrille; Cook, Jacquelynn J.; Van Laere, Koen; Evelhoch, Jeffrey L. 分享 收藏
High-resolution peripheral quantitative computed tomography and finite element analysis of bone strength at the distal radius in ovariectomized adult rhesus monkey demonstrate efficacy of odanacatib and differentiation from alendronate Cabal, Antonio; Jayakar, Richa Y.; Sardesai, Swanand; Phillips, Eual A.; Szumiloski, John; Posavec, Diane J.; Mathers, Parker D.; Savitz, Alan T.; Scott, Boyd B.; Winkelmann, Christopher T.; Motzel, Sherri; Cook, Lynn; Hargreaves, Richard; Evelhoch, Jeffrey L.; Dardzinski, Bernard J.; Hangartner, Thomas N.; McCracken, Paul J.; Duong, Le T.; Williams, Donald S. 分享 收藏
Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: A head-to-head comparison with alendronate odanacatib对去卵巢猴子的骨转换标志物，骨密度以及脊柱和臀部的几何形状的影响: 与阿仑膦酸钠的头对头比较 Williams, Donald S.; McCracken, Paul J.; Purcell, Mona; Pickarski, Maureen; Mathers, Parker D.; Savitz, Alan T.; Szumiloski, John; Jayakar, Richa Y.; Somayajula, Sangeetha; Krause, Stephen; Brown, Keenan; Winkelmann, Christopher T.; Scott, Boyd B.; Cook, Lynn; Motzel, Sherri L.; Hargreaves, Richard; Evelhoch, Jeffrey L.; Cabal, Antonio; Dardzinski, Bernard J.; Hangartner, Thomas N.; Duong, Le T. 分享 收藏
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[11C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor Bell, Ian M.; Gallicchio, Steven N.; Stump, Craig A.; Bruno, Joseph G.; Fan, Hong; Gantert, Liza T.; Hostetler, Eric D.; Kemmerer, Amanda L.; McWherter, Melody; Moore, Eric L.; Mosser, Scott D.; Purcell, Mona L.; Riffel, Kerry; Salvatore, Christopher A.; Sanabria-Bohorquez, Sandra; Staas, Donnette D.; White, Rebecca B.; Williams, Mangay; Zartman, C. Blair; Cook, Jacquelynn J.; Hargreaves, Richard J.; Kane, Stefanie A.; Graham, Samuel L.; Selnick, Harold G. 分享 收藏
2-[(3aR,4R,5S,7aS)-5-{(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxyethoxy}-4-(2-methylphenyl)octahydro-2H-isoindol-2-yl]-1,3-oxazol-4(5H)-one: A Potent Human NK1 Receptor Antagonist with Multiple Clearance Pathways Kassick, Andrew J.; Jiang, Jinlong; Bunda, Jaime; Wilson, David; Bao, Jianming; Lu, Huagang; Lin, Peter; Ball, Richard G.; Doss, George A.; Tong, Xinchun; Tsao, Kwei-Lan C.; Wang, Hong; Chicchi, Gary; Karanam, Bindhu; Tschirret-Guth, Richard; Samuel, Koppara; Hora, Donald F.; Kumar, Sanjeev; Madeira, Maria; Eng, Waisi; Hargreaves, Richard; Purcell, Mona; Gantert, Liza; Cook, Jacquelyn; DeVita, Robert J.; Mills, Sander G. 分享 收藏
Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABAA Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats Fox, Steven V.; Gotter, Anthony L.; Tye, Spencer J.; Garson, Susan L.; Savitz, Alan T.; Uslaner, Jason M.; Brunner, Joseph I.; Tannenbaum, Pamela L.; McDonald, Terrence P.; Hodgson, Robert; Yao, Lihang; Bowlby, Mark R.; Kuduk, Scott D.; Coleman, Paul J.; Hargreaves, Richard; Winrow, Christopher J.; Renger, John J. 分享 收藏
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