未登录Tyrosine kinase inhibitor, masitinib, limits neuronal damage, as measured by serum neurofilament light chain concentration in a model of neuroimmune-driven neurodegenerative disease酪氨酸激酶抑制剂masitinib可限制神经损伤，如通过血清神经丝轻链浓度测量的神经免疫驱动型神经退行性疾病模型所示。
Hermine, Olivier; Gros, Laurent; Tran, Truong-An; Loussaief, Lamya; Flosseau, Kathleen; Moussy, Alain; Mansfield, Colin D.; Vermersch, Patrick .png)
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收藏Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial (vol 15, 39, 2023)Dubois, Bruno; Lopez-Arrieta, Jesus; Lipschitz, Stanley; Doskas, Triantafyllos; Spiru, Luiza; Moroz, Svitlana; Venger, Olena; Vermersch, Patrick; Moussy, Alain D.; Mansfield, Colin; Hermine, Olivier; Tsolaki, Magda 分享 收藏 Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trialDubois, Bruno; Lopez-Arrieta, Jesus; Lipschitz, Stanley; Triantafyllos, Doskas; Spiru, Luiza; Moroz, Svitlana; Venger, Olena; Vermersch, Patrick; Moussy, Alain; Mansfield, Colin D. D.; Hermine, Olivier; Tsolaki, Magda 分享 收藏 Mast Cell Diseases in Practice and Research: Issues and Perspectives Raised by Patients and Their Recommendations to the Scientific Community and BeyondJennings, Susan, V; Finnerty, Celeste C.; Hobart, Jessica S.; Martin-Martinez, Mercedes; Sinclair, Kristin A.; Slee, Valerie M.; Agopian, Julie; Akin, Cem; Alvarez-Twose, Ivan; Bonadonna, Patrizia; Bowman, Angela S.; Brockow, Knut; Bumbea, Horia; de Haro, Claudia; Fok, Jie Shen; Hartmann, Karin; Hegmann, Nicole; Hermine, Olivier; Kalisiak, Monika; Katelaris, Constance H.; Kurz, Jacqueline; Marcis, Patrizia; Mayne, David; Mendoza, David; Moussy, Alain; Mudretzkyj, Genija; Vaia, Nicoleta Nidelea; Niedoszytko, Marek; Elberink, Hanneke Oude; Orfao, Alberto; Radia, Deepti H.; Rosenmeier, Sophie; Ribada, Eugenia; Schinhofen, Waltraud; Schwaab, Juliana; Siebenhaar, Frank; Triggiani, Massimo; Tripodo, Giuseppe; Velazquez, Rocio; Wielink, Yvon; Wimazal, Friedrich; Yigit, Timo; Zubrinich, Celia; Valent, Peter 分享 收藏 Efficacy and Safety of Masitinib in Corticosteroid-Dependent Severe Asthma: A Randomized Placebo-Controlled TrialDavidescu, Lavinia; Ursol, Grigoriy; Korzh, Oleksii; Deshmukh, Vikranth; Kuryk, Lesia; Nortje, Monja-Marie; Godlevska, Olga; Devouassoux, Gilles; Khodosh, Eduard; Israel, Elliot; Moussy, Alain; Mansfield, Colin; Hermine, Olivier; Chanez, Pascal 分享 收藏 Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis A Randomized, Phase 3, Clinical TrialVermersch, Patrick; Brieva-Ruiz, Luis; Fox, Robert J.; Paul, Friedemann; Ramio-Torrenta, Lluis; Schwab, Matthias; Moussy, Alain; Mansfield, Colin; Hermine, Olivier; Maciejowski, Maciej 分享 收藏 Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology用于合理设计多药理学的双重蛋白激酶和核苷激酶调节剂Hammam, Kahina; Saez-Ayala, Magali; Rebuffet, Etienne; Gros, Laurent; Lopez, Sophie; Hajem, Berengere; Humbert, Martine; Baudelet, Emilie; Audebert, Stephane; Betzi, Stephane; Lugari, Adrien; Combes, Sebastien; Letard, Sebastien; Casteran, Nathalie; Mansfield, Colin; Moussy, Alain; De Sepulveda, Paulo; Morelli, Xavier; Dubreuil, Patrice 分享 收藏 分享 收藏 Masitinib for treatment of severely symptomatic indolent systemic mastocytosis: a randomised, placebo-controlled, phase 3 study马赛替尼治疗严重症状性惰性系统性肥大细胞增多症: 一项随机、安慰剂对照、3期研究Lortholary, Olivier; Chandesris, Marie Olivia; Livideanu, Cristina Bulai; Paul, Carle; Guillet, Gerard; Jassem, Ewa; Niedoszytko, Marek; Barete, Stephane; Verstovsek, Srdan; Grattan, Clive; Damaj, Gandhi; Canioni, Danielle; Fraitag, Sylvie; Lhermitte, Ludovic; Georgin-Lavialle, Sophie; Frenzel, Laurent; Afrin, Lawrence B.; Hanssens, Katia; Agopian, Julie; Gaillard, Raphael; Kinet, Jean-Pierre; Auclair, Christian; Mansfield, Colin; Moussy, Alain; Dubreuil, Patrice; Hermine, Olivier 分享 收藏 Masitinib plus FOLFIRI for second-line treatment of metastatic colorectal cancer: 2-year follow-up of phase 2, open label trialTaieb, J.; Borg, C.; Lecomte, T.; Lepere, C.; Chatellier, T.; Smith, D.; Dubreuil, P.; Mansfield, C.; Moussy, A.; Hermine, O. 分享 收藏 分享 收藏 Phase 1b/2 study results for masitinib plus irinotecan in second-line treatment of esophagogastric adenocarcinomaZaanan, A.; Bennouna, J.; Hiret, S.; Douillard, J. Y.; Bouche, O.; Tougeron, D.; Lecomte, T.; Ezenfis, J.; Lepere, C.; Mansfield, C.; Moussy, A.; Dubreuil, P.; Hermine, O.; Taieb, J. 分享 收藏 A randomized, placebo-controlled phase III trial of masitinib plus gemcitabine in the treatment of advanced pancreatic cancer马赛替尼联合吉西他滨治疗晚期胰腺癌的随机，安慰剂对照III期试验Deplanque, G.; Demarchi, M.; Hebbar, M.; Flynn, P.; Melichar, B.; Atkins, J.; Nowara, E.; Moye, L.; Piquemal, D.; Ritter, D.; Dubreuil, P.; Mansfield, C. D.; Acin, Y.; Moussy, A.; Hermine, O.; Hammel, P. 分享 收藏 分享 收藏 分享 收藏 Masitinib in advanced gastrointestinal stromal tumor (GIST) after failure of imatinib: A randomized controlled open-label trialAdenis, A.; Blay, J. -Y.; Bui-Nguyen, B.; Bouche, O.; Bertucci, F.; Isambert, N.; Bompas, E.; Chaigneau, L.; Domont, J.; Ray-Coquard, I.; Blesius, A.; Van Tine, B. A.; Bulusu, V. R.; Dubreuil, P.; Mansfield, C. D.; Acin, Y.; Moussy, A.; Hermine, O.; Le Cesne, A. 分享 收藏 Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trialPiette, Francois; Belmin, Joel; Vincent, Helene; Schmidt, Nicolas; Pariel, Sylvie; Verny, Marc; Marquis, Caroline; Mely, Jean; Hugonot-Diener, Laurence; Kinet, Jean-Pierre; Dubreuil, Patrice; Moussy, Alain; Hermine, Olivier 分享 收藏 Masitinib for the treatment of systemic and cutaneous mastocytosis with handicap: A phase 2a studyPaul, Carle; Sans, Beatrix; Suarez, Felipe; Casassus, Philippe; Barete, Stephane; Lanternier, Fanny; Grandpeix-Guyodo, Catherine; Dubreuil, Patrice; Palmerini, Fabienne; Mansfield, Colin D.; Gineste, Paul; Moussy, Alain; Hermine, Olivier; Lortholary, Olivier 分享 收藏 Phase II study of oral masitinib mesilate in imatinib-naive patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST)Le Cesne, Axel; Blay, Jean-Yves; Bui, Binh Nguyen; Bouche, Olivier; Adenis, Antoine; Domont, Julien; Cioffi, Angela; Ray-Coquard, Isabelle; Lassau, Nathalie; Bonvalot, Sylvie; Moussy, Alain; Kinet, Jean-Pierre; Hermine, Olivier 分享 收藏 Pediatric Mastocytosis Is a Clonal Disease Associated with D816V and Other Activating c-KIT MutationsBodemer, Christine; Hermine, Olivier; Palmerini, Fabienne; Yang, Ying; Grandpeix-Guyodo, Catherine; Leventhal, Phillip S.; Hadj-Rabia, Smail; Nasca, Laurent; Georgin-Lavialle, Sophie; Cohen-Akenine, Annick; Launay, Jean-Marie; Barete, Stephane; Feger, Frederic; Arock, Michel; Catteau, Benoit; Sans, Beatrix; Stalder, Jean Francois; Skowron, Francois; Thomas, Luc; Lorette, Gerard; Plantin, Patrice; Bordigoni, Pierre; Lortholary, Olivier; de Prost, Yves; Moussy, Alain; Sobol, Hagay; Dubreuil, Patrice 分享 收藏 
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