未登录 Trends and variation in issuance of high-cost narcolepsy drugs by NHS England organisations and regions from 2019 to 2022 van Someren, Frederick; Wiedemann, Milan; Warren-Gash, Charlotte; Sykorova, Martina; Mistry, Hema; Miller, Michelle A.; Leschziner, Guy; Nolte, Ellen; Belot, Aurelien; Smith, Ian E.; Quinnell, Tim; Eriksson, Sofia H.; Strongman, Helen 分享 收藏
Longitudinal monitoring of circulating tumor DNA to detect relapse early and predict outcome in early breast cancer Garcia-Murillas, Isaac; Cutts, Rosalind J.; Walsh-Crestani, Giselle; Phillips, Edward; Hrebien, Sarah; Dunne, Kathryn; Sidhu, Kally; Daber, Robert; Hubert, Benjamin; Graybill, Chiharu; Deford, Peter M.; Wooten, David J.; Zhao, Jianhua; Ellsworth, Rachel E.; Johnston, Stephen R. D.; Ring, Alistair; Russell, Simon; Evans, Abigail; Skene, Anthony; Wheatley, Duncan; Smith, Ian E.; Korn, W. Michael; Turner, Nicholas C. 分享 收藏
Association of post-operative ctDNA detection with outcomes of patients with early breast cancers 术后ctDNA检测与早期乳腺癌患者预后的关系 Cutts, R.; Ulrich, L.; Beaney, M.; Roberta, M.; Coakley, M.; Bbunce, C.; Crestani, G. W.; Hrebien, S.; Kalashnikova, E.; Wu, H. -t.; Dashner, S.; Sethi, H.; Aleshin, A.; Liu, M.; Ring, A.; Okines, A.; Smith, I. E.; Barry, P.; Turner, N. C.; Garcia-Murillas, I. 分享 收藏
Comparison of mathematically arterialised venous blood gas sampling with arterial, capillary, and venous sampling in adult patients with hypercapnic respiratory failure: a single-centre longitudinal cohort study Davies, Michael Gordon; Wozniak, Dariusz Rafal; Quinnell, Timothy George; Palas, Earl; George, Susan; Huang, Yingchang; Jayasekara, Ruwanthi; Stoneman, Victoria; Smith, Ian Edward; Thomsen, Lars Pilegaard; Rees, Stephen Edward 分享 收藏
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HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer Bergamino, Milana A.; Lopez-Knowles, Elena; Morani, Gabriele; Tovey, Holly; Kilburn, Lucy; Schuster, Eugene F.; Alataki, Anastasia; Hills, Margaret; Xiao, Hui; Holcombe, Chris; Skene, Anthony; Robertson, John F.; Smith, Ian E.; Bliss, Judith M.; Dowsett, Mitch; Cheang, Maggie C. U. 分享 收藏
Detection of ctDNA following surgery predicts relapse in breast cancer patients receiving primary surgery Garcia-Murillas, Isaac; Cutts, Rosalind J.; Ulrich, Lara; Beaney, Matthew; Robert, Marie; Coakley, Maria; Bunce, Catey; WalshCrestani, Giselle; Hrebien, Sarah; Kalashnikova, Ekaterina; Wu, Hsin-Ta; Dashner, Scott; Sethi, Himanshu; Aleshin, Alexey; Ring, Alistair; Okines, Alicia; Smith, Ian E.; Dowsett, Mitch; Barry, Peter; Turner, Nicholas C. 分享 收藏
Clinical outcomes in patients with triple negative or HER2 positive lobular breast cancer: a single institution experience Okines, Alicia; Irfan, Tazia; Asare, Bernice; Mohammed, Kabir; Osin, Peter; Nerurkar, Ashutosh; Smith, Ian E.; Parton, Marina; Ring, Alistair; Johnston, Stephen; Turner, Nicholas C. 分享 收藏
Impact of the menstrual cycle on commercial prognostic gene signatures in oestrogen receptor-positive primary breast cancer Haynes, Ben P.; Schuster, Gene; Buus, Richard; Alataki, Anastasia; Ginsburg, Ophira; Le Hong Quang; Pham Thi Han; Pham Hong Khoa; Nguyen Van Dinh; Ta Van To; Clemons, Mark; Holcombe, Chris; Osborne, Caroline; Evans, Abigail; Skene, Anthony; Sibbering, Mark; Rogers, Clare; Laws, Siobhan; Noor, Lubna; Cheang, Maggie Chon U.; Cleator, Susan J.; Smith, Ian E.; Dowsett, Mitch 分享 收藏
Optimization of a Series of RIPK2 PROTACs 一系列RIPK2 PROTACs的优化 Miah, Afjal H.; Smith, Ian E. D.; Rackham, Mark; Mares, Alina; Thawani, Aditya R.; Nagilla, Rakesh; Haile, Pamela A.; Votta, Bartholomew J.; Gordon, Laurie J.; Watt, Gillian; Denyer, Jane; Fisher, Don T.; Dace, Phoebe; Giffen, Paul; Goncalves, Andrea; Churcher, Ian; Scott-Stevens, Paul; Harling, John D. 分享 收藏
Impact of timing of adjuvant chemothapy for early breast cancer: the Royal Marsden Hospital experience Okines, Alicia F. C.; Kipps, Emma; Irfan, Tazia; Coakley, Maria; Angelis, Vaselios; Asare, Bernice; Mohammed, Kabir; Walsh, Geraldine; Ring, Alistair; Johnston, Stephen R. D.; Parton, Marina; Turner, Nicholas C.; Smith, Ian E. 分享 收藏
Updated results from the international phase III ALTTO trial (BIG 2-06/Alliance N063D)Presented at the 2017 annual meeting of the American Society of Clinical Oncology 在美国临床肿瘤学会2017年会上发表的国际III期ALTTO试验 (BIG 2-06/Alliance N063D) 的最新结果 Moreno-Aspitia, Alvaro; Holmes, Eileen M.; Jackisch, Christian; de Azambuja, Evandro; Boyle, Frances; Hillman, David W.; Korde, Larissa; Fumagalli, Debora; Izquierdo, Miguel A.; McCullough, Ann E.; Wolff, Antonio C.; Pritchard, Kathleen, I; Untch, Michael; Guillaume, Sebastien; Ewer, Michael S.; Shao, Zhimin; Sim, Sung Hoon; Aziz, Zeba; Demetriou, Georgia; Mehta, Ajay O.; Andersson, Michael; Toi, Masakazu; Lang, Istvan; Xu, Binghe; Smith, Ian E.; Barrios, Carlos H.; Baselga, Jose; Gelber, Richard D.; Piccart-Gebhart, Martine 分享 收藏
Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group Ki67在乳腺癌中的评估: 国际Ki67乳腺癌工作组的最新建议 Nielsen, Torsten O.; Leung, Samuel C. Y.; Rimm, David L.; Dodson, Andrew; Acs, Balazs; Badve, Sunil; Denkert, Carsten; Ellis, Matthew J.; Fineberg, Susan; Flowers, Margaret; Kreipe, Hans H.; Laenkholm, Anne-Vibeke; Pan, Hongchao; Penault-Llorca, Friderique M.; Polley, Mei-Yin; Salgado, Roberto; Smith, Ian E.; Sugie, Tomoharu; Bartlett, John M. S.; McShane, Lisa M.; Dowsett, Mitch; Hayes, Daniel F. 分享 收藏
Evidence-based guidelines for managing patients with primary ER+ HER2- breast cancer deferred from surgery due to the COVID-19 pandemic Dowsett, Mitch; Ellis, Matthew J.; Dixon, J. Michael; Gluz, Oleg; Robertson, John; Kates, Ronald; Suman, Vera J.; Turnbull, Arran K.; Nitz, Ulrike; Christgen, Matthias; Kreipe, Hans; Kuemmel, Sherko; Bliss, Judith M.; Barry, Peter; Johnston, Stephen R.; Jacobs, Samuel A.; Ma, Cynthia X.; Smith, Ian E.; Harbeck, Nadia 分享 收藏
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 Mares, Alina; Miah, Afjal H.; Smith, Ian E. D.; Rackham, Mark; Thawani, Aditya R.; Cryan, Jenni; Haile, Pamela A.; Votta, Bartholomew J.; Beal, Allison M.; Capriotti, Carol; Reilly, Michael A.; Fisher, Don T.; Zinn, Nico; Bantscheff, Marcus; MacDonald, Thomas T.; Vossenkamper, Anna; Dace, Phoebe; Churcher, Ian; Benowitz, Andrew B.; Watt, Gillian; Denyer, Jane; Scott-Stevens, Paul; Harling, John D. 分享 收藏
Early Enrichment of ESR1 Mutations and the Impact on Gene Expression in Presurgical Primary Breast Cancer Treated with Aromatase Inhibitors Leal, Mariana Ferreira; Haynes, Ben P.; Schuster, Eugene; Yeo, Belinda; Afentakis, Maria; Zabaglo, Lila; Martins, Vera; Buus, Richard; Dodson, Andrew; Cheang, Maggie C. U.; Smith, Ian E.; Martin, Lesley-Ann; Dowsett, Mitch 分享 收藏
Menstrual cycle associated changes in hormone-related gene expression in oestrogen receptor positive breast cancer Haynes, Ben P.; Ginsburg, Ophira; Gao, Qiong; Folkerd, Elizabeth; Afentakis, Maria; Buus, Richard; Le Hong Quang; Pham Thi Han; Pham Hong Khoa; Nguyen Van Dinh; Ta Van To; Clemons, Mark; Holcombe, Chris; Osborne, Caroline; Evans, Abigail; Skene, Anthony; Sibbering, Mark; Rogers, Clare; Laws, Siobhan; Noor, Lubna; Smith, Ian E.; Dowsett, Mitch 分享 收藏
Free-Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N-Methylation for PI3Kδ Activity Barnes, Lydia; Blaber, Hollie; Brooks, David T. K.; Byers, Lewis; Buckley, Daniel; Byron, Zoe C.; Chilvers, Richard G.; Cochrane, Liam; Cooney, Edward; Damian, Heather A.; Francis, Luke; He, Daniel Fu; Grace, Jack M. J.; Green, Harley J.; Hogarth, Edmund J. P.; Jusu, Leyla; Killalea, C. Elizabeth; King, Oliver; Lambert, Joseph; Lee, Zoe J.; Lima, Nuria S.; Long, Christina L.; Mackinnon, May-Li; Mahdy, Shusha; Matthews-Wright, Jolyon; Millward, Makenzie J.; Meehan, Matthew F.; Merrett, Christopher; Morrison, Lisa; Parke, Hal R. I.; Payne, Charlotte; Payne, Lawrence; Pike, Craig; Seal, Alexander; Senior, Aaron J.; Smith, Keenan M.; Stanelyte, Kamile; Stillibrand, Joe; Szpara, Rachel; Taday, Freya F. H.; Threadgould, Antony M.; Trainor, Rohan J.; Waters, Jordan; Williams, Oliver; Wong, Carrie K. W.; Wood, Katherine; Barton, Nick; Gruszka, Anna; Henley, Zoe; Rowedder, James E.; Cookson, Rosa; Jones, Katherine L.; Nadin, Alan; Smith, Ian E.; Macdonald, Simon J. F.; Nortcliffe, Andrew 分享 收藏
The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors Deaton, David N.; Do, Young; Holt, Jason; Jeune, Michael R.; Kramer, H. Fritz; Larkin, Andrew L.; Orband-Miller, Lisa A.; Peckham, Gregory E.; Poole, Chuck; Price, Daniel J.; Schaller, Lee T.; Shen, Ying; Shewchuk, Lisa M.; Stewart, Eugene L.; Stuart, J. Darren; Thomson, Stephen A.; Ward, Paris; Wilson, Joseph W.; Xu, Tianshun; Guss, Jeffrey H.; Musetti, Caterina; Rendina, Alan R.; Affleck, Karen; Anders, David; Hancock, Ashley P.; Hobbs, Heather; Hodgson, Simon T.; Hutchinson, Jonathan; Leveridge, Melanie V.; Nicholls, Harry; Smith, Ian E. D.; Somers, Don O.; Sneddon, Helen F.; Uddin, Sorif; Cleasby, Anne; Mortenson, Paul N.; Richardson, Caroline; Saxty, Gordon 分享 收藏
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding Tinworth, Christopher P.; Lithgow, Hannah; Dittus, Lars; Bassi, Zuni I.; Hughes, Sophie E.; Muelbaier, Marcel; Dai, Han; Smith, Ian E. D.; Kerr, William J.; Burley, Glenn A.; Bantscheff, Marcus; Harling, John D. 分享 收藏
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