未登录 ATI-2173, a Novel Liver-Targeted Non-Chain-Terminating Nucleotide for Hepatitis B Virus Cure Regimens Squires, Katherine E.; Mayers, Douglas L.; Bluemling, Gregory R.; Kolykhalov, Alexander A.; Guthrie, David B.; Reddy, Prabhakar; Mitchell, Debbie G.; Saindane, Manohar T.; Sticher, Zachary M.; Edpuganti, Vindhya; De La Rosa, Abel 分享 收藏
A randomized, double-blind, multiple-dose study of the pan-genotypic NS5A inhibitor samatasvir in patients infected with hepatitis C virus genotype 1, 2, 3 or 4 Vince, Bradley; Hill, John M.; Lawitz, Eric J.; O'Riordan, William; Webster, Lynn R.; Gruener, Daniel M.; Mofsen, Ricky S.; Murillo, Abel; Donovan, Eileen; Chen, Jie; McCarville, Joseph F.; Sullivan-Bolyai, John Z.; Mayers, Douglas; Zhou, Xiao-Jian 分享 收藏
A PHASE II STUDY OF SAMATASVIR (IDX719) IN COMBINATION WITH SIMEPREVIR AND RIBAVIRIN IN TREATMENT-NAIVE HCV-INFECTED SUBJECTS WITH GENOTYPES 1B AND 4 (HELIX-1 STUDY) Lawitz, E.; Rodriguez-Torres, M.; Nguyen, T.; Sheikh, A.; Tobias, H.; Galati, J.; Hill, J.; Lok, A.; Nelson, D.; Patrick, G. Dubuc; Chen, J.; Frank, D.; Zhou, X. J.; Sullivan-Bolyai, Z.; Mayers, D. 分享 收藏
Short-Term Monotherapy with IDX184, a Liver-Targeted Nucleotide Polymerase Inhibitor, in Patients with Chronic Hepatitis C Virus Infection Lalezari, Jacob; Asmuth, David; Casiro, Arnaldo; Vargas, Hugo; Lawrence, Shannon; Dubuc-Patrick, Gloria; Chen, Jie; McCarville, Joseph; Pietropaolo, Keith; Zhou, Xiao-Jian; Sullivan-Bolyai, John; Mayers, Douglas 分享 收藏
First-in-Human Study of the Pharmacokinetics and Antiviral Activity of IDX375, a Novel Nonnucleoside Hepatitis C Virus Polymerase Inhibitor de Bruijne, J.; de Rooij, J. van de Wetering; van Vliet, A. A.; Zhou, X. J.; Temam, M. F.; Molles, J.; Chen, J.; Pietropaolo, K.; Sullivan-Bolyai, J. Z.; Mayers, D.; Reesink, H. W. 分享 收藏
Drug interaction profile for GSK2248761, a next generation non-nucleoside reverse transcriptase inhibitor Piscitelli, Steve; Kim, Joseph; Gould, Elizabeth; Lou, Yu; White, Scott; de Serres, Mark; Johnson, Mark; Zhou, Xiao-Jian; Pietropaolo, Keith; Mayers, Douglas 分享 收藏
Safety and Efficacy of GSK2248761, a Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor, in Treatment-Naive HIV-1-Infected Subjects Zala, Carlos; St Clair, Marty; Dudas, Kathleen; Kim, Joseph; Lou, Yu; White, Scott; Piscitelli, Steve; Dumont, Etienne; Pietropaolo, Keith; Zhou, Xiao-Jian; Mayers, Douglas 分享 收藏
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ANTIVIRAL ACTIVITY, PHARMACOKINETICS AND SAFETY OF IDX184 IN COMBINATION WITH PEGYLATED INTERFERON (PEGIFN) AND RIBAVIRIN (RBV) IN TREATMENT-NAIVE HCV GENOTYPE 1-INFECTED SUBJECTS Lalezari, J.; Poordad, F.; Mehra, P.; Nguyen, T.; Dejesus, E.; Godofsky, E.; Patrick, G. Dubuc; Chen, J.; Pietropaolo, K.; Zhou, X. -J.; Sullivan-Bolyai, J. Z.; Mayers, D. 分享 收藏
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Single-Dose Escalation and Multiple-Dose Safety, Tolerability, and Pharmacokinetics of IDX899, a Candidate Human Immunodeficiency Virus Type 1 Nonnucleoside Reverse Transcriptase Inhibitor, in Healthy Subjects Zhou, Xiao-Jian; Pietropaolo, Keith; Damphousse, David; Belanger, Bruce; Chen, Jie; Sullivan-Bolyai, John; Mayers, Douglas 分享 收藏
IDX184, A LIVER-TARGETED NUCLEOTIDE HCV POLYMERASE INHIBITOR: RESULTS OF A FIRST-IN-MAN SAFETY AND PHARMACOKINETIC STUDY Zhou, X. -J.; Pietropaolo, K.; Sullivan-Bolyai, J.; Kuca, B.; Liu, W.; Xu, L.; Belanger, B.; Khan, S.; Mayers, D. 分享 收藏
HIV-1 drug resistance in variants from the female genital tract and plasma Kemal, Kimdar Sherefa; Burger, Harold; Mayers, Douglas; Anastos, Kathryn; Foley, Brian; Kitchen, Christina; Huggins, Penelope; Schroeder, Tamara; Picchio, Gaston; Back, Sara; Gao, Wei; Meyer, William A., III; Weiser, Barbara 分享 收藏
Ritonavir-boosted tipranavir demonstrates superior efficacy to ritonavir-boosted protease inhibitors in treatment-experienced HIV-infected patients:: 24-week results of the RESIST-2 trial Cahn, Pedro; Villacian, Jorge; Lazzarin, Adriano; Katlama, Christine; Grinsztejn, Beatriz; Arasteh, Keikawus; Lopez, Paulo; Clumeck, Nathan; Gerstoft, Jan; Stavrianeas, Nikolas; Moreno, Santiago; Antunes, Francisco; Neubacher, Dietmar; Mayers, Douglas 分享 收藏
Efficacy of the protease inhibitors tipranavir plus ritonavir in treatment-experienced patients: 24-week analysis from the RESIST-1 trial Gathe, Joseph; Cooper, David A.; Farthing, Charles; Jayaweera, Dushyantha; Norris, Dorece; Pierone, Gerald, Jr.; Steinhart, Corklin R.; Trottier, Benoit; Walmsley, Sharon L.; Workman, Cassy; Mukwaya, Geoffrey; Kohlbrenner, Veronika; Dohnanyi, Catherine; McCallister, Scott; Mayers, Douglas 分享 收藏
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Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the Randomized Evaluation of Strategic Intervention in multi-drug resistant patients with Tipranavir (RESIST) studies: an analysis of combined data from two randomised open-label trials Hicks, Charles B.; Cahn, Pedro; Cooper, David A.; Walmsley, Sharon L.; Katlama, Christine; Clotet, Bonaventura; Lazzarin, Adriano; Johnson, Margaret A.; Neubacher, Dietmar; Mayers, Douglas; Valdez, Hernan 分享 收藏
Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus Lawrence, J; Mayers, DL; Hullsiek, KH; Collins, G; Abrams, DI; Reisler, RB; Crane, LR; Schmetter, BS; Dionne, TJ; Saldanha, JM; Jones, MC; Baxter, JD 分享 收藏
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