Peter C. Isakson - Publications, H-index & Citations

Peter C. Isakson

机构信息待补充

65H指数

194论文数

2.2W被引数

收录论文 33

发表时间

Valdecoxib: Assessment of cyclooxygenase-2 potency and selectivity

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2005-03-01

PREAI

Gierse, JK; Zhang, Y; Hood, WF; Walker, MC; Trigg, JS; Maziasz, TJ; Koboldt, CM; Muhammad, JL; Zweifel, BS; Masferrer, JL; Isakson, PC; Seibert, K

Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IF11.2

2003-05-01

123

PREAI

Gyllfors, P; Bochenek, G; Overholt, J; Drupka, D; Kumlin, M; Sheller, J; Nizankowska, E; Isakson, PC; Mejza, F; Lefkowith, JB; Dahlén, SE; Szczeklik, A; Murray, JJ; Dahlén, B

Characterization of celecoxib and valdecoxib binding to cyclooxygenase

MOLECULAR PHARMACOLOGY

IF3

2003-04-01

PREAI

Hood, WF; Gierse, JK; Isakson, PC; Kiefer, JR; Kurumbail, RG; Seibert, K; Monahan, JB

Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

NEUROMOLECULAR MEDICINE

IF3.9

2003-01-01

PREAI

Vidensky, S; Zhang, Y; Hand, T; Goellner, J; Shaffer, A; Isakson, P; Andreasson, K

1,2-DIARYLCYCLOPENTENES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS AND ORALLY-ACTIVE ANTIINFLAMMATORY AGENTS

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2002-05-01

235

PREAI

LI, JJ; ANDERSON, GD; BURTON, EG; COGBURN, JN; COLLINS, JT; GARLAND, DJ; GREGORY, SA; HUANG, HC; ISAKSON, PC; KOBOLDT, CM; LOGUSCH, EW; NORTON, MB; PERKINS, WE; REINHARD, EJ; SEIBERT, K; VEENHUIZEN, AW; ZHANG, Y; REITZ, DB

Pharmacology of celecoxib in rat brain after kainate administration

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2002-01-01

PREAI

Ciceri, P; Zhang, Y; Shaffer, AF; Leahy, KM; Woerner, MB; Smith, WG; Seibert, K; Isakson, PC

A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors

BIOCHEMICAL JOURNAL

IF4.3

2001-08-01

OAAI

Walker, MC; Kurumbail, RG; Kiefer, JR; Moreland, KT; Koboldt, CM; Isakson, PC; Seibert, K; Gierse, JK

Selective cyclooxygenase-2 inhibitors: Heteroaryl modified 1,2-diarylimidazoles are potent, orally active antiinflammatory agents

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2000-07-21

132

PREAI

Khanna, IK; Yu, Y; Huff, RM; Weier, RM; Xu, XD; Koszyk, FJ; Collins, PW; Cogburn, JN; Isakson, PC; Koboldt, CM; Masferrer, JL; Perkins, WE; Seibert, K; Veenhuizen, AW; Yuan, JH; Yang, DC; Zhang, YY

Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison

LANCET

IF88.5

1999-12-01

453

PREAI

Emery, P; Zeidler, H; Kvien, TK; Guslandi, M; Naudin, R; Stead, H; Verburg, KM; Isakson, PC; Hubbard, RC; Geis, GS

Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis - A randomized controlled trial

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IF55

1999-11-24

692

PREAI

Simon, LS; Weaver, AL; Graham, DY; Kivitz, AJ; Lipsky, PE; Hubbard, RC; Isakson, PC; Verburg, KM; Yu, SS; Zhao, WW; Geis, GS

Treatment of osteoarthritis with celecoxib, a cyclooxygenase-2 inhibitor: A randomized controlled trial

MAYO CLINIC PROCEEDINGS

IF6.7

1999-11-01

289

PREAI

Bensen, WG; Fiechtner, JJ; McMillen, JI; Zhao, WW; Yu, SS; Woods, EM; Hubbard, RC; Isakson, PC; Verburg, KM; Geis, GS

Kinetic basis for selective inhibition of cyclo-oxygenases

BIOCHEMICAL JOURNAL

IF4.3

1999-05-01

265

OAAI

Gierse, JK; Koboldt, CM; Walker, MC; Seibert, K; Isakson, PC

Cyclooxygenase-2 (COX-2) plays a significant role in regulating the fetal ductus arteriosus in vivo and in vitro

PEDIATRIC RESEARCH

IF3.1

1999-04-01

OAAI

Takahashi, Y; Maziasz, T; Paulson, S; Isakson, P; Heymann, MA; Chemtob, S; Clyman, RI

Transformation of intestinal epithelial cells by chronic TGF-β1 treatment results in downregulation of the type II TGF-β receptor and induction of cyclooxygenase-2

ONCOGENE

IF7.3

1999-02-08

PREAI

Sheng, HM; Shao, JY; O'Mahony, CA; Lamps, L; Albo, D; Isakson, PC; Berger, DH; DuBois, RN; Beauchamp, RD

Pharmacological analysis of cyclooxygenase-1 in inflammation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

1998-10-27

762

OAAI

Smith, CJ; Zhang, Y; Koboldt, CM; Muhammad, J; Zweifel, BS; Shaffer, A; Talley, JJ; Masferrer, JL; Seibert, K; Isakson, PC

Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

1998-09-01

334

OAAI

Nakayama, M; Uchimura, K; Zhu, RL; Nagayama, T; Rose, ME; Stetler, RA; Isakson, PC; Chen, J; Graham, SH

Spinal and systemic cyclooxygenase (COX) inhibitors suppress paw carrageenan-evoked thermal hyperalgesia in rats

ANESTHESIOLOGY

IF9.1

1997-09-01

PREAI

Dirig, DM; Isakson, PC; Yaksh, TL

Effect of spinal cyclooxygenase inhibitors in rat using the formalin test and in vitro prostaglandin E-2 release

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

1997-07-01

PREAI

Dirig, DM; Konin, GP; Isakson, PC; Yaksh, TL

1,2-diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

1997-05-23

226

PREAI

Khanna, IK; Weier, RM; Yu, Y; Collins, PW; Miyashiro, JM; Koboldt, CM; Veenhuizen, AW; Currie, JL; Seibert, K; Isakson, PC

1,2-diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

1997-05-23

229

PREAI

Khanna, IK; Weier, RM; Yu, Y; Xu, XD; Koszyk, FJ; Collins, PW; Koboldt, CM; Veenhuizen, AW; Perkins, WE; Casler, JJ; Masferrer, JL; Zhang, YY; Gregory, SA; Seibert, K; Isakson, PC

研究方向