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Integrated multiomic profiling identifies genomic and immune microenvironmental changes as candidate resistance mechanisms to PD-1 blockade in high-grade meningiomas 整合多组学分析鉴定出基因组改变和免疫微环境变化为高级别脑膜瘤对PD-1阻断治疗的候选耐药机制 Gritsch, David; Jia-Ren, Lin; Haehnel, Philipp; Coy, Shannon; Zhang, Britney; Sullivan, Emily; Nayyar, Naema; Cahill, Daniel P.; Barker, Fred G.; Gerstner, Elizabeth R.; Santagata, Sandro; Brastianos, Priscilla K. 分享 收藏
LONG-TERM EFFICACY AND SAFETY OF BEVACIZUMAB FOR PROGRESSIVE VESTIBULAR SCHWANNOMA IN PATIENTS WITHNF2-RELATED SCHWANNOMATOSIS (NF2-SWN) 贝伐珠单抗治疗进展性前庭神经鞘瘤在NF2相关神经鞘瘤病(NF2-SWN)患者中的长期有效性与安全性 Stec, Natalie; Lee, Veronica; Barker II, Fred; Welling, D. Bradley; Muzikansky, Alona; Merker, Vanessa; Jain, Rakesh; Orr, Christina; Jordan, Justin; Plotkin, Scott 分享 收藏
SCHWANNOMAS DISPLAY CONSERVED CELLULAR STATES AND PREFERENTIAL MHC CLASS II ANTIGEN PRESENTATION ACROSS DIFFERENT GENETIC BACKGROUNDS AND ANATOMIC LOCATIONS 神经鞘瘤表现出保守的细胞状态,并在不同的遗传背景和解剖位置上表现出对MHC II类抗原的优先呈递。 Gonzalez Castro, L.; Gavish, A.; Bussema, L.; Mount, C.; Neftel, C.; Nomura, M.; Chiocca, E.; Bi, W.; Arnaout, O.; Barker, F.; Brown, J.; Jordan, J.; Batchelor, T.; Stemmer-Rachamimov, A.; Plotkin, S.; Tirosh, I; Suva, M. L. 分享 收藏
Mesothelin is a surface antigen present on human meningioma and can be effectively targeted by CAR T-cells Ramapriyan, R.; Barker, F.G., 2nd; Richardson, L.G.; Sun, J.; Vandecandelaere, G.; Shim, J.M.; De Vlaminck, G.; Gaffey, M.; Grewal, E.P.; Tazhibi, M.; et al. 纤维蛋白是存在于人类脑膜瘤表面的抗原,并且可以被CAR T细胞有效靶向。Neuro-Oncology 2025, noaf155. [Google Scholar] [CrossRef] Ramapriyan, Rishab; Barker, Fred G.; Richardson, Leland G.; Sun, Jing; Vandecandelaere, Gust; Shim, Jane M.; De Vlaminck, Guillaume; Gaffey, Matthew; Grewal, Eric P.; Tazhibi, Masih; Morshedy, Kourosh; Aref, Amir R.; Batool, Syeda M.; Guo, Xiaopeng; Ijad, Nazanin; Balaj, Leonora; Wakimoto, Hiroaki; Martinez-Lage, Maria; Frigault, Matthew J.; Leick, Mark B.; Bernstock, Joshua D.; Bi, Wenya Linda; Carter, Bob S.; Chiocca, E. Antonio; Dietrich, Jorg; Gerstner, Elizabeth R.; Boland, Genevieve M.; Nahed, Brian, V; Plotkin, Scott R.; Jenkins, Russell W.; Brastianos, Priscilla K.; Curry, William T.; Maus, Marcela, V; Choi, Bryan D. 分享 收藏
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Patients May Return to Work Sooner After Laminoplasty: Occupational Outcomes of the Cervical Spondylotic Myelopathy Surgical Trial 椎板成形术后患者可能会更快恢复工作: 脊髓型颈椎病手术试验的职业结局 Miranda, Stephen P.; Whitmore, Robert G.; Kanter, Adam; Mummaneni, Praveen V.; Bisson, Erica F.; Barker II, Fred G.; Harrop, James; Magge, Subu N.; Heary, Robert F.; Fehlings, Michael G.; Albert, Todd J.; Arnold, Paul M.; Riew, K. Daniel; Steinmetz, Michael P.; Wang, Marjorie C.; Heller, John G.; Benzel, Edward C.; Ghogawala, Zoher 分享 收藏
Radical surgical resection with molecular margins is associated with improved survival in IDH wild-type glioblastoma 具有分子切缘的根治性手术切除与IDH野生型胶质母细胞瘤的生存率提高有关 Massaad, Elie; Smith, William J.; Bradley, Joseph; Esposito, Eric; Gupta, Mihir; Burns, Evan; Burns, Ryan; Velarde, Jose K.; Berglar, Inka K.; Gupta, Rajiv; Martinez-Lage, Maria; Dietrich, Jorg; Lennerz, Jochen K.; Dunn, Gavin P.; Jones, Pamela S.; Choi, Bryan D.; Kim, Albert E.; Frosch, Matthew; Barker, Fred G.; Curry, William T.; Carter, Bob S.; Nahed, Brian, V; Cahill, Daniel P.; Shankar, Ganesh M. 分享 收藏
County-level disparities in care for patients with glioblastoma Ramapriyan, Rishab; Ramesh, Tarun; Yu, Hao; Richardson, Leland G.; Nahed, Brian V.; Carter, Bob S.; Barker, Fred G., II; Curry, William T.; Choi, Bryan D. 分享 收藏
BRAF-MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas Brastianos, Priscilla K.; Twohy, Erin; Geyer, Susan; Gerstner, Elizabeth R.; Kaufmann, Timothy J.; Tabrizi, Shervin; Kabat, Brian; Thierauf, Julia; Ruff, Michael W.; Bota, Daniela A.; Reardon, David A.; Cohen, Adam L.; De La Fuente, Macarena I.; Lesser, Glenn J.; Campian, Jian; Agarwalla, Pankaj K.; Kumthekar, Priya; Mann, Bhupinder; Vora, Shivangi; Knopp, Michael; Iafrate, A. John; Curry, William T., Jr.; Cahill, Daniel P.; Shih, Helen A.; Brown, Paul D.; Santagata, Sandro; Barker, Fred G., II; Galanis, Evanthia 分享 收藏
Prospective phase II trial of the dual mTORC1/2 inhibitor vistusertib for progressive or symptomatic meningiomas in persons with neurofibromatosis 2 Jordan, Justin T.; Orr, Christina C.; Thalheimer, Raquel D.; Cambillo, Josephine, V; Beauchamp, Roberta L.; Shaikh, Ghalib; Muzikansky, Alona; Stemmer-Rachamimov, Anat; Giovannini, Marco; Kalamarides, Michel; Barker, Fred G.; Ramesh, Vijaya; Plotkin, Scott R. 分享 收藏
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Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas Brastianos, Priscilla K.; Kim, Albert E.; Giobbie-Hurder, Anita; Lee, Eudocia Quant; Wang, Nancy; Eichler, April F.; Chukwueke, Ugonma; Forst, Deborah A.; Arrillaga-Romany, Isabel C.; Dietrich, Jorg; Corbin, Zachary; Moliterno, Jennifer; Baehring, Joachim; White, Michael; Lou, Kevin W.; Larson, Juliana; de Sauvage, Magali A.; Evancic, Kathryn; Mora, Joana; Nayyar, Naema; Loeffler, Jay; Oh, Kevin; Shih, Helen A.; Curry, William T.; Cahill, Daniel P.; Barker, Fred G.; Gerstner, Elizabeth R.; Santagata, Sandro 分享 收藏
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Effect of Ventral vs Dorsal Spinal Surgery on Patient-Reported Physical Functioning in Patients With Cervical Spondylotic Myelopathy A Randomized Clinical Trial Ghogawala, Zoher; Terrin, Norma; Dunbar, Melissa R.; Breeze, Janis L.; Freund, Karen M.; Kanter, Adam S.; Mummaneni, Praveen V.; Bisson, Erica F.; Barker, Fred G., II; Schwartz, J. Sanford; Harrop, James S.; Magge, Subu N.; Heary, Robert F.; Fehlings, Michael G.; Albert, Todd J.; Arnold, Paul M.; Riew, K. Daniel; Steinmetz, Michael P.; Wang, Marjorie C.; Whitmore, Robert G.; Heller, John G.; Benzel, Edward C. 分享 收藏
Sporadic multiple meningiomas harbor distinct driver mutations Juratli, Tareq A.; Prilop, Insa; Saalfeld, Felix C.; Herold, Sylvia; Meinhardt, Matthias; Wenzel, Carina; Zeugner, Silke; Aust, Daniela E.; Barker, Fred G., II; Cahill, Daniel P.; Brastianos, Priscilla K.; Santagata, Sandro; Schackert, Gabriele; Pinzer, Thomas 分享 收藏
Adjuvant Radiation Therapy Versus Surveillance After Surgical Resection of Atypical Meningiomas Lee, Grace; Lamba, Nayan; Niemierko, Andrzej; Kim, Daniel W.; Chapman, Paul H.; Loeffler, Jay S.; Curry, William T.; Martuza, Robert L.; Oh, Kevin S.; Barker, Fred G., II; Shih, Helen A. 分享 收藏
Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic Williams, Erik A.; Santagata, Sandro; Wakimoto, Hiroaki; Shankar, Ganesh M.; Barker, Fred G., II; Sharaf, Radwa; Reddy, Abhinav; Spear, Phoebe; Alexander, Brian M.; Ross, Jeffrey S.; Brastianos, Priscilla K.; Cahill, Daniel P.; Ramkissoon, Shakti H.; Juratli, Tareq A. 分享 收藏