未登录 Development, initial validation, and application of a visual read method for [18F]MK-6240 tau PET [18F]MK-6240 tau PET视觉读取方法的开发，初步验证和应用 Shuping, Joanna L.; Matthews, Dawn C.; Adamczuk, Katarzyna; Scott, David; Rowe, Christopher C.; Kreisl, William C.; Johnson, Sterling C.; Lukic, Ana S.; Johnson, Keith A.; Rosa-Neto, Pedro; Andrews, Randolph D.; Van Laere, Koen; Cordes, Lindsay; Ward, Larry; Wilde, Claire L.; Barakos, Jerome; Purcell, Derk D.; Devanand, Davangere P.; Stern, Yaakov; Luchsinger, Jose A.; Sur, Cyrille; Price, Julie C.; Brickman, Adam M.; Klunk, William E.; Boxer, Adam L.; Mathotaarachchi, Sulantha S.; Lao, Patrick J.; Evelhoch, Jeffrey L. 分享 收藏
Evaluation of 18F-flutemetamol amyloid PET image analysis parameters on the effect of verubecestat on brain amlyoid load in Alzheimer's disease Sur, Cyrille; Adamczuk, Katarzyna; Scott, David; Kost, James; Sampat, Mehul; Buckley, Christopher; Farrar, Gill; Newton, Ben; Suhy, Joyce; Bennacef, Idriss; Egan, Michael F. 分享 收藏
The Worldwide Alzheimer's Disease Neuroimaging Initiative: ADNI-3 updates and global perspectives Weber, Christopher J.; Carrillo, Maria C.; Jagust, William; Jack, Clifford R., Jr.; Shaw, Leslie M.; Trojanowski, John Q.; Saykin, Andrew J.; Beckett, Laurel A.; Sur, Cyrille; Rao, Naren P.; Mendez, Patricio Chrem; Black, Sandra E.; Li, Kuncheng; Iwatsubo, Takeshi; Chang, Chiung-Chih; Sosa, Ana Luisa; Rowe, Christopher C.; Perrin, Richard J.; Morris, John C.; Healan, Amanda M. B.; Hall, Stephen E.; Weiner, Michael W. 分享 收藏
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A multisite analysis of the concordance between visual image interpretation and quantitative analysis of [18F]flutemetamol amyloid PET images [18F]flutemetamol淀粉样蛋白PET图像的视觉图像解释与定量分析之间一致性的多站点分析 Bucci, Marco; Savitcheva, Irina; Farrar, Gill; Salvado, Gemma; Collij, Lyduine; Dore, Vincent; Gispert, Juan Domingo; Gunn, Roger; Hanseeuw, Bernard; Hansson, Oskar; Shekari, Mahnaz; Lhommel, Renaud; Molinuevo, Jose Luis; Rowe, Christopher; Sur, Cyrille; Whittington, Alex; Buckley, Christopher; Nordberg, Agneta 分享 收藏
Retinal Optical Coherence Tomography Metrics Are Unchanged in Verubecestat Alzheimer's Disease Clinical Trial but Correlate with Baseline Regional Brain Atrophy Sergott, Robert C.; Raji, Annaswamy; Kost, James; Sur, Cyrille; Jackson, Saheeda; Locco, Amy; Patel, Arpankumar; Furtek, Christine; Mattson, Britta; Egan, Michael F. 分享 收藏
BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain Sur, Cyrille; Kost, James; Scott, David; Adamczuk, Katarzyna; Fox, Nick C.; Cummings, Jeffrey L.; Tariot, Pierre N.; Aisen, Paul S.; Vellas, Bruno; Voss, Tiffini; Mahoney, Erin; Mukai, Yuki; Kennedy, Matthew E.; Lines, Christopher; Michelson, David; Egan, Michael F. 分享 收藏
MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy Wang, Xiaohai; Li, Wenping; Marcus, Jacob; Pearson, Michelle; Song, Lixin; Smith, Karen; Terracina, Giuseppe; Lee, Julie; Hong, Kwok-Lam Karen; Lu, Sherry X.; Hyde, Lynn; Chen, Shu-Cheng; Kinsley, David; Melchor, Jerry P.; Rubins, Daniel J.; Meng, Xiangjun; Hostetler, Eric; Sur, Cyrille; Zhang, Lili; Schachter, Joel B.; Hess, J. Fred; Selnick, Harold G.; Vocadlo, David J.; McEachern, Ernest J.; Uslaner, Jason M.; Duffy, Joseph L.; Smith, Sean M. 分享 收藏
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Preclinical Safety Evaluation and Human Dosimetry of [18F]MK-6240, a Novel PET Tracer for Imaging Neurofibrillary Tangles Koole, Michel; Lohith, Talakad G.; Valentine, John L.; Bennacef, Idriss; Declercq, Ruben; Reynders, Tom; Riffel, Kerry; Celen, Sofie; Serdons, Kim; Bormans, Guy; Ferry-Martin, Sandrine; Laroque, Philippe; Walji, Abbas; Hostetler, Eric D.; Briscoe, Richard J.; de Hoon, Jan; Sur, Cyrille; Van Laere, Koen; Struyk, Arie 分享 收藏
Randomized Trial of Verubecestat for Prodromal Alzheimer's Disease Egan, Michael F.; Kost, James; Voss, Tiffini; Mukai, Yuki; Aisen, Paul S.; Cummings, Jeffrey L.; Tariot, Pierre N.; Vellas, Bruno; van Dyck, Christopher H.; Boada, Merce; Zhang, Ying; Li, Wen; Furtek, Christine; Mahoney, Erin; Mozley, Lyn Harper; Mo, Yi; Sur, Cyrille; Michelson, David 分享 收藏
Brain Imaging of Alzheimer Dementia Patients and Elderly Controls with 18F-MK-6240, a PET Tracer Targeting Neurofibrillary Tangles Lohith, Talakad G.; Bennacef, Idriss; Vandenberghe, Rik; Vandenbulcke, Mathieu; Salinas, Cristian A.; Declercq, Ruben; Reynders, Tom; Telan-Choing, N. Florestina; Riffel, Kerry; Celen, Sofie; Serdons, Kim; Bormans, Guy; Tsai, Kuenhi; Walji, Abbas; Hostetler, Eric D.; Evelhoch, Jeffrey L.; Van Laere, Koen; Forman, Mark; Stoch, Aubrey; Sur, Cyrille; Struyk, Arie 分享 收藏
Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer's Disease Egan, Michael F.; Kost, James; Tariot, Pierre N.; Aisen, Paul S.; Cummings, Jeffrey L.; Vellas, Bruno; Sur, Cyrille; Mukai, Yuki; Voss, Tiffini; Furtek, Christine; Mahoney, Erin; Mozley, Lyn Harper; Vandenberghe, Rik; Mo, Yi; Michelson, David 分享 收藏
Chronic Verubecestat Treatment Suppresses Amyloid Accumulation in Advanced Aged Tg2576-AβPPswe Mice Without Inducing Microhemorrhage Villarreal, Stephanie; Zhao, Fuqiang; Hyde, Lynn A.; Holder, Daniel; Forest, Thomas; Sondey, Marie; Chen, Xia; Sur, Cyrille; Parker, Eric M.; Kennedy, Matthew E. 分享 收藏
In Vivo Quantification of Calcitonin Gene-Related Peptide Receptor Occupancy by Telcagepant in Rhesus Monkey and Human Brain Using the Positron Emission Tomography Tracer [11C]MK-4232 Hostetler, Eric D.; Joshi, Aniket D.; Sanabria-Bohorquez, Sandra; Fan, Hong; Zeng, Zhizhen; Purcell, Mona; Gantert, Liza; Riffel, Kerry; Williams, Mangay; O'Malley, Stacey; Miller, Patricia; Selnick, Harold G.; Gallicchio, Steven N.; Bell, Ian M.; Salvatore, Christopher A.; Kane, Stefanie A.; Li, Chi-Chung; Hargreaves, Richard J.; de Groot, Tjibbe; Bormans, Guy; Van Hecken, Anne; Derdelinckx, Inge; de Hoon, Jan; Reynders, Tom; Declercq, Ruben; De Lepeleire, Inge; Kennedy, W. P.; Blanchard, Rebecca; Marcantonio, Eugene E.; Sur, Cyrille; Cook, Jacquelynn J.; Van Laere, Koen; Evelhoch, Jeffrey L. 分享 收藏
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A fluorogenic near-infrared imaging agent for quantifying plasma and local tissue renin activity in vivo and ex vivo Zhang, Jun; Preda, Dorin V.; Vasquez, Kristine O.; Morin, Jeff; Delaney, Jeannine; Bao, Bagna; Percival, M. David; Xu, Daigen; McKay, Dan; Klimas, Michael; Bednar, Bohumil; Sur, Cyrille; Gao, David Z.; Madden, Karen; Yared, Wael; Rajopadhye, Milind; Peterson, Jeffrey D. 分享 收藏
[18F]Fluoroazabenzoxazoles as potential amyloid plaque PET tracers: synthesis and in vivo evaluation in rhesus monkey Hostetler, Eric D.; Sanabria-Bohorquez, Sandra; Fan, Hong; Zeng, Zhizhen; Gammage, Linda; Miller, Patricia; O'Malley, Stacey; Connolly, Brett; Mulhearn, James; Harrison, Scott T.; Wolkenberg, Scott E.; Barrow, James C.; Williams, David L., Jr.; Hargreaves, Richard J.; Sur, Cyrille; Cook, Jacquelynn J. 分享 收藏
Synthesis and Evaluation of 5-Fluoro-2-aryloxazolo[5,4-b]pyridines as β-Amyloid PET Ligands and Identification of MK-3328 Harrison, Scott T.; Mulhearn, James; Wolkenberg, Scott E.; Miller, Patricia J.; O'Malley, Stacey S.; Zeng, Zhizhen; Williams, David L., Jr.; Hostetler, Eric D.; Sanabria-Bohorquez, Sandra; Gammage, Linda; Fan, Hong; Sur, Cyrille; Culberson, J. Christopher; Hargreaves, Richard J.; Cook, Jacquelynn J.; Hartman, George D.; Barrow, James C. 分享 收藏
Ex Vivo Imaging of Pancreatic Beta Cells using a Radiolabeled GLP-1 Receptor Agonist Connolly, Brett M.; Vanko, Amy; McQuade, Paul; Guenther, Ilonka; Meng, Xiangjun; Rubins, Daniel; Waterhouse, Rikki; Hargreaves, Richard; Sur, Cyrille; Hostetler, Eric 分享 收藏
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