未登录 Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery 在适应性随机I-SPY2试验中，以Trebananib和紫杉醇为基础的新辅助化疗治疗II/III期乳腺癌的疗效和生物标志物发现 Albain, Kathy S.; Yau, Christina; Petricoin, Emanuel F.; Wolf, Denise M.; Lang, Julie E.; Chien, A. Jo; Haddad, Tufia; Forero-Torres, Andres; Wallace, Anne M.; Kaplan, Henry; Pusztai, Lajos; Euhus, David; Nanda, Rita; Elias, Anthony D.; Clark, Amy S.; Godellas, Constantine; Boughey, Judy C.; Isaacs, Claudine; Tripathy, Debu; Lu, Janice; Yung, Rachel L.; Gallagher, Rosa I.; Wulfkuhle, Julia D.; Brown-Swigart, Lamorna; Krings, Gregor; Chen, Yunn Yi; Potter, David A.; Stringer-Reasor, Erica; Blair, Sarah; Asare, Smita M.; Wilson, Amy; Hirst, Gillian L.; Singhrao, Ruby; Buxton, Meredith; Clennell, Julia L.; Sanil, Ashish; Berry, Scott; Asare, Adam L.; Matthews, Jeffrey B.; Demichele, Angela M.; Hylton, Nola M.; Melisko, Michelle; Perlmutter, Jane; Rugo, Hope S.; Symmans, W. Fraser; van't Veer, Laura J.; Yee, Douglas; Berry, Donald A.; Esserman, Laura J. 分享 收藏
Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer Lang, Julie E.; Forero-Torres, Andres; Yee, Douglas; Yau, Christina; Wolf, Denise; Park, John; Parker, Barbara A.; Chien, A. Jo; Wallace, Anne M.; Murthy, Rashmi; Albain, Kathy S.; Ellis, Erin D.; Beckwith, Heather; Haley, Barbara B.; Elias, Anthony D.; Boughey, Judy C.; Yung, Rachel L.; Isaacs, Claudine; Clark, Amy S.; Han, Hyo S.; Nanda, Rita; Khan, Qamar J.; Edmiston, Kristen K.; Stringer-Reasor, Erica; Price, Elissa; Joe, Bonnie; Liu, Minetta C.; Brown-Swigart, Lamorna; Petricoin, Emanuel F.; Wulfkuhle, Julia D.; Buxton, Meredith; Clennell, Julia L.; Sanil, Ashish; Berry, Scott; Asare, Smita M.; Wilson, Amy; Hirst, Gillian L.; Singhrao, Ruby; Asare, Adam L.; Matthews, Jeffrey B.; Melisko, Michelle; Perlmutter, Jane; Rugo, Hope S.; Symmans, W. Fraser; van't Veer, Laura J.; Hylton, Nola M.; DeMichele, Angela M.; Berry, Donald A.; Esserman, Laura J. 分享 收藏
Analysis of clinical outcomes and expression-based immune signatures by race in the I-SPY 2 trial Kyalwazi, Beverly; Yau, Christina; Olopade, Olufunmilayo; Chien, A. Jo; Wallace, Anne; Forero-Torres, Andres; Pusztai, Lajos; Ellis, Erin; Albain, Kathy; Blaes, Anne; Haley, Barbara; Boughey, Judy; Elias, Anthony; Clark, Amy; Isaacs, Claudine; Nanda, Rita; Han, Hyo; Yung, Rachel; Tripathy, Debu; Edmiston, Kristen; Viscusi, Rebecca; Northfelt, Donald; Khan, Qamar; Sanil, Ashish; Berry, Scott; Asare, Smita; Wilson, Amy; Hirst, Gillian; Hylton, Nola; Melisko, Michelle; Perlmutter, Jane; Rugo, Hope; Symmans, Fraser; van 't Veer, Laura; Berry, Donald; Esserman, Laura 分享 收藏
Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial 新辅助T-DM1/帕妥珠单抗和紫杉醇/曲妥珠单抗/帕妥珠单抗治疗HER2乳腺癌的适应性随机I-SPY2试验 Clark, Amy S.; Yau, Christina; Wolf, Denise M.; Petricoin, Emanuel F.; Veer, Laura J. van't; Yee, Douglas; Moulder, Stacy L.; Wallace, Anne M.; Chien, A. Jo; Isaacs, Claudine; Boughey, Judy C.; Albain, Kathy S.; Kemmer, Kathleen; Haley, Barbara B.; Han, Hyo S.; Forero-Torres, Andres; Elias, Anthony; Lang, Julie E.; Ellis, Erin D.; Yung, Rachel; Tripathy, Debu; Nanda, Rita; Wulfkuhle, Julia D.; Brown-Swigart, Lamorna; Gallagher, Rosa, I; Helsten, Teresa; Roesch, Erin; Ewing, Cheryl A.; Alvarado, Michael; Crane, Erin P.; Buxton, Meredith; Clennell, Julia L.; Paoloni, Melissa; Asare, Smita M.; Wilson, Amy; Hirst, Gillian L.; Singhrao, Ruby; Steeg, Katherine; Asare, Adam; Matthews, Jeffrey B.; Berry, Scott; Sanil, Ashish; Melisko, Michelle; Perlmutter, Jane; Rugo, Hope S.; Schwab, Richard B.; Symmans, W. Fraser; Hylton, Nola M.; Berry, Donald A.; Esserman, Laura J.; DeMichele, Angela M. 分享 收藏
Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer Yee, Douglas; Isaacs, Claudine; Wolf, Denise M.; Yau, Christina; Haluska, Paul; Giridhar, Karthik V.; Forero-Torres, Andres; Jo Chien, A.; Wallace, Anne M.; Pusztai, Lajos; Albain, Kathy S.; Ellis, Erin D.; Beckwith, Heather; Haley, Barbara B.; Elias, Anthony D.; Boughey, Judy C.; Kemmer, Kathleen; Yung, Rachel L.; Pohlmann, Paula R.; Tripathy, Debu; Clark, Amy S.; Han, Hyo S.; Nanda, Rita; Khan, Qamar J.; Edmiston, Kristen K.; Petricoin, Emanuel F.; Stringer-Reasor, Erica; Falkson, Carla I.; Majure, Melanie; Mukhtar, Rita A.; Helsten, Teresa L.; Moulder, Stacy L.; Robinson, Patricia A.; Wulfkuhle, Julia D.; Brown-Swigart, Lamorna; Buxton, Meredith; Clennell, Julia L.; Paoloni, Melissa; Sanil, Ashish; Berry, Scott; Asare, Smita M.; Wilson, Amy; Hirst, Gillian L.; Singhrao, Ruby; Asare, Adam L.; Matthews, Jeffrey B.; Hylton, Nola M.; DeMichele, Angela; Melisko, Michelle; Perlmutter, Jane; Rugo, Hope S.; Fraser Symmans, W.; Van't Veer, Laura J.; Berry, Donald A.; Esserman, Laura J. 分享 收藏
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19 The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial Angus, Derek C.; Derde, Lennie; Al-Beidh, Farah; Annane, Djillali; Arabi, Yaseen; Beane, Abigail; Van Bentum-Puijk, Wilma; Berry, Lindsay; Bhimani, Zahra; Bonten, Marc; Bradbury, Charlotte; Brunkhorst, Frank; Buxton, Meredith; Buzgau, Adrian; Cheng, Allen C.; de Jong, Menno; Detry, Michelle; Estcourt, Lise; Fitzgerald, Mark; Goossens, Herman; Green, Cameron; Haniffa, Rashan; Higgins, Alisa M.; Horvat, Christopher; Hullegie, Sebastiaan J.; Kruger, Peter; Lamontagne, Francois; Lawler, Patrick R.; Linstrum, Kelsey; Litton, Edward; Lorenzi, Elizabeth; Marshall, John; McAuley, Daniel; McGlothin, Anna; McGuinness, Shay; McVerry, Bryan; Montgomery, Stephanie; Mouncey, Paul; Murthy, Srinivas; Nichol, Alistair; Parke, Rachael; Parker, Jane; Rowan, Kathryn; Sanil, Ashish; Santos, Marlene; Saunders, Christina; Seymour, Christopher; Turner, Anne; van de Veerdonk, Frank; Venkatesh, Balasubramanian; Zarychanski, Ryan; Berry, Scott; Lewis, Roger J.; McArthur, Colin; Webb, Steven A.; Gordon, Anthony C. 分享 收藏
Evaluation of patritumab/paclitaxel/trastuzumab over standard paclitaxel/trastuzumab in early stage, high-risk HER2 positive breast cancer: Results from the neoadjuvant I-SPY 2 trial Helsten, Teresa L.; Lo, Shelly S.; Yau, Christina; Kalinsky, Kevin; Elias, Anthony D.; Wallace, Anne M.; Chien, A. Jo; Lu, Janice; Lang, Julie E.; Albain, Kathy S.; Stringer-Reasor, Erica; Clark, Amy S.; Boughey, Judy C.; Ellis, Erin D.; Yee, Douglas; DeMichele, Angela; Isaacs, Claudine; Perlmutter, Jane; Rugo, Hope S.; Schwab, Richard; Hylton, Nola M.; Symmans, W. Fraser; Melisko, Michelle E.; van't Veer, Laura J.; Wilson, Amy; Singhrao, Ruby; Asare, Smita M.; Sanil, Ashish; Berry, Donald A.; Esserman, Laura J. 分享 收藏
Evaluation of a novel agent plus standard neoadjuvant therapy in early stage, high-risk HER2 negative breast cancer: Results from the I-SPY 2 TRIAL Liu, Minetta C.; Robinson, Patricia A.; Yau, Christina; Wallace, Anne M.; Chien, A. Jo; Stringer-Reasor, Erica; Nanda, Rita; Yee, Douglas; Albain, Kathy S.; Boughey, Judy C.; Han, Heather S.; Elias, Anthony D.; Kalinsky, Kevin; Clark, Amy S.; Kemmer, Kathleen; Isaacs, Claudine; Lang, Julie E.; Lu, Janice; Sanft, Tara; DeMichele, Angela; Hylton, Nola M.; Melisko, Michelle E.; Perlmutter, Jane; Rugo, Hope S.; Schwab, Richard; Symmans, W. Fraser; van't Veer, Laura J.; Haugen, Patricia K.; Wilson, Amy; Singhrao, Ruby; Asare, Smita; Sanil, Ashish; Berry, Donald A.; Esserman, Laura J. 分享 收藏
Refining neoadjuvant predictors of three year distant metastasis free survival: Integrating volume change as measured by MRI with residual cancer burden Hylton, N. M.; Symmans, W. F.; Yau, C.; Li, W.; Hatzis, C.; Isaacs, C.; Albain, K. S.; Chen, Y-Y; Krings, G.; Wei, S.; Harada, S.; Datnow, B.; Fadare, O.; Klein, M.; Pambuccian, S.; Chen, B.; Adamson, K.; Sams, S.; Mhawech-Fauceglia, P.; Magliocco, A.; Feldman, M.; Rendi, M.; Sattar, H.; Zeck, J.; Ocal, I.; Tawfik, O.; LeBeau, L. Grasso; Sahoo, S.; Vinh, T.; Yang, S.; Adams, A.; Chien, A. J.; Ferero-Torres, A.; Stringer-Reasor, E.; Wallace, A.; Boughey, J. C.; Ellis, E. D.; Elias, A. D.; Lang, J. E.; Lu, J.; Han, H. S.; Clark, A. S.; Korde, L.; Nanda, R.; Northfelt, D. W.; Khan, Q. J.; Viscusi, R. K.; Euhus, D. M.; Edmiston, K. K.; Chui, S. Y.; Kemmer, K.; Wood, W. C.; Park, J. W.; Liu, M. C.; Olopade, O.; Tripathy, D.; Moulder, S. L.; Rugo, H. S.; Schwab, R.; Lo, S.; Helsten, T.; Beckwith, H.; Haugen, P. K.; van't Veer, L. J.; Perlmutter, J.; Melisko, M. E.; Wilson, A.; Peterson, G.; Asare, A. L.; Buxton, M. B.; Paoloni, M.; Clennell, J. L.; Hirst, G. L.; Singhrao, R.; Steeg, K.; Matthews, J. B.; Sanil, A.; Berry, S. M.; Abe, H.; Wolverton, D.; Crane, E. P.; Ward, K. A.; Nelson, M.; Niell, B. L.; Oh, K.; Brandt, K. R.; Bang, D. H.; Ojeda-Fournier, H.; Eghtedari, M.; Sheth, P. A.; Bernreuter, W. K.; Umphrey, H.; Rosen, M. A.; Dogan, B.; Yang, W.; Joe, B.; Yee, D.; Pusztai, L.; DeMichele, A.; Asare, S. M.; Berry, D. A.; Esserman, L. J. 分享 收藏
DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial Wolf, Denise M.; Yau, Christina; Sanil, Ashish; Glas, Annuska; Petricoin, Emanuel; Wulfkuhle, Julia; Severson, Tesa M.; Linn, Sabine; Brown-Swigart, Lamorna; Hirst, Gillian; Buxton, Meredith; DeMichele, Angela; Hylton, Nola; Symmans, Fraser; Yee, Doug; Paoloni, Melissa; Esserman, Laura; Berry, Don; Rugo, Hope; Olopade, Olufunmilayo; van t'Veer, Laura 分享 收藏
DNA repair deficiency biomarkers and MammaPrint high1/(ultra)high2 risk as predictors of veliparib/carboplatin response: Results from the neoadjuvant I-SPY 2 trial for high risk breast cancer Wolf, D. M.; Yau, C.; Sanil, A.; Glas, A.; Petricoin, C.; Wulfkuhle, J.; Brown-Swigart, L.; Hirst, G.; Buxton, M.; DeMichele, A.; Hylton, N.; Symmans, F.; Yee, D.; Paoloni, M.; Esserman, L.; Berry, D.; Rugo, H.; Olapade, O.; van't Veer, L. 分享 收藏
Efficacy of pertuzumab/trastuzumab /paclitaxel over standard trastuzumab/paclitaxel therapy for HER2+breast cancer: Results from the neoadjuvant I-SPY 2 TRIAL Buxton, Meredith; DeMichele, Angela M.; Chia, Stephen; van't Veer, Laura; Chien, Jo; Wallace, Anne; Kaplan, Henry; Lang, Julie; Yee, Douglas; Isaacs, Claudine; Moulder, Stacy; Albain, Kathy; Boughey, Judy; Kemmer, Kathleen; Haley, Barbara; Minton, Susan; Forero, Andres; Nanda, Rita; Elias, Anthony; Korde, Larissa; Viscuzi, Rebecca; Rugo, Hope; Schwab, Richard; Symmans, Fraser; Paoloni, Melissa; Hylton, Nola; Hogarth, Michael; Lyandres, Julia; Perlmutter, Jane; Sanil, Ashish; Yau, Christina; Esserman, Laura; Berry, Don 分享 收藏
Efficacy of T-DM1+pertuzumab over standard therapy for HER2+breast cancer: Results from the neoadjuvant I -SPY 2 TRIAL DeMichele, Angela M.; Moulder, Stacy; Buxton, Meredith; Yee, Douglas; Wallace, Anne; Chien, Jo; Isaacs, Claudine; Albain, Kathy; Boughey, Judy; Kemmer, Kathleen; Haley, Barbara; Lang, Julie; Kaplan, Henry; Minton, Susan; Forero, Andres; Elias, Anthony; Nanda, Rita; Korde, Larissa; Schwab, Richard; Melisko, Michelle; Sanil, Ashish; Hogarth, Michael; Hylton, Nola; Paoloni, Melissa; Symmans, Fraser; Perlmutter, Jane; Lyandres, Julia; Yau, Christina; Berry, Don; Esserman, Laura 分享 收藏
Combining sensitivity markers to identify triple-negative breast cancer patients most responsive to veliparib/carboplatin: results from the I-SPY 2 TRIAL Wolf, Denise M.; Yau, Christina; Sanil, Ashish; Brown-Swigart, Lamorna; Hirst, Gillian; Buxton, Meredith; Paoloni, Melissa; Olopade, Olufunmilayo; Rugo, Hope; De Michele, Angela; Symmans, Fraser; Berry, Don; Esserman, Laura; van't Veer, Laura 分享 收藏
Adaptive Randomization of Neratinib in Early Breast Cancer Park, J. W.; Liu, M. C.; Yee, D.; Yau, C.; van 't Veer, L. J.; Symmans, W. F.; Paoloni, M.; Perlmutter, J.; Hylton, N. M.; Hogarth, M.; DeMichele, A.; Buxton, M. B.; Chien, A. J.; Wallace, A. M.; Boughey, J. C.; Haddad, T. C.; Chui, S. Y.; Kemmer, K. A.; Kaplan, H. G.; Isaacs, C.; Nanda, R.; Tripathy, D.; Albain, K. S.; Edmiston, K. K.; Elias, A. D.; Northfelt, D. W.; Pusztai, L.; Moulder, S. L.; Lang, J. E.; Viscusi, R. K.; Euhus, D. M.; Haley, B. B.; Khan, Q. J.; Wood, W. C.; Melisko, M.; Schwab, R.; Helsten, T.; Lyandres, J.; Davis, S. E.; Hirst, G. L.; Sanil, A.; Esserman, L. J.; Berry, D. A. 分享 收藏
Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer Rugo, H. S.; Olopade, O. I.; DeMichele, A.; Yau, C.; van 't Veer, L. J.; Buxton, M. B.; Hogarth, M.; Hylton, N. M.; Paoloni, M.; Perlmutter, J.; Symmans, W. F.; Yee, D.; Chien, A. J.; Wallace, A. M.; Kaplan, H. G.; Boughey, J. C.; Haddad, T. C.; Albain, K. S.; Liu, M. C.; Isaacs, C.; Khan, Q. J.; Lang, J. E.; Viscusi, R. K.; Pusztai, L.; Moulder, S. L.; Chui, S. Y.; Kemmer, K. A.; Elias, A. D.; Edmiston, K. K.; Euhus, D. M.; Haley, B. B.; Nanda, R.; Northfelt, D. W.; Tripathy, D.; Wood, W. C.; Ewing, C.; Schwab, R.; Lyandres, J.; Davis, S. E.; Hirst, G. L.; Sanil, A.; Berry, D. A.; Esserman, L. J. 分享 收藏
The evaluation of trebananib plus standard neoadjuvant therapy in high-risk breast cancer: Results from the I-SPY 2 TRIAL Albain, K. S.; Leyland-Jones, B.; Symmans, F.; Paoloni, M.; van't Veer, L.; DeMichele, A.; Buxton, M.; Hylton, N.; Yee, D.; Clennell, J. Lyandres; Yau, C.; Sanil, A.; Berry, D.; Esserman, L. 分享 收藏
Evaluation of an in vitro derived signature of olaparib response (PARPi-7) as a predictive biomarker of response to veliparib/carboplatin plus standard neoadjuvant therapy in high-risk breast cancer: Results from the I-SPY 2 TRIAL Wolf, Denise M.; Yau, Christina; Sanil, Ashish; Daemen, Anneleen; Heiser, Laura; Gray, Joe; Brown-Swigart, Lamorna; Flynn, Susan; Hirst, Gillian; Buxton, Meredith; DeMichele, Angela; Hylton, Nola; Symmans, Fraser; Yee, Doug; Paoloni, Melissa; Esserman, Laura; Berry, Don; Rugo, Hope; Olopade, Olufunmilayo; van't Veer, Laura 分享 收藏
Evaluation of a BRCAness signature as a predictive biomarker of response to veliparib/carboplatin plus standard neoadjuvant therapy in high-risk breast cancer: results from the I-SPY 2 trial Glas, A.; Peeters, J.; Yau, C.; Wolf, D. M.; Sanil, A.; Li, Y.; Severson, T.; Linn, S.; Buxton, M.; DeMichele, A.; Hylton, N.; Symmans, F.; Yee, D.; Paoloni, M.; Esserman, L.; Berry, D.; Rugo, H.; Olopade, O.; van 't Veer, L. J. 分享 收藏
Neratinib plus standard neoadjuvant therapy for high-risk breast cancer: Efficacy results from the I-SPY 2 TRIAL Park, John W.; Liu, Minetta C.; Yee, Douglas; DeMichele, Angela; van't Veer, Laura; Hylton, Nola; Symmans, Fraser; Buxton, Meredith B.; Chien, A. Jo; Wallace, Amy; Melisko, Michelle; Schwab, Richard; Boughey, Judy; Tripathy, Debashish; Kaplan, Hank; Nanda, Rita; Chui, Stephen; Albain, Kathy S.; Moulder, Stacy; Elias, Anthony; Lang, Julie E.; Edminston, Kirsten; Northfelt, Donald; Euhus, David; Khan, Qamar; Lyandres, Julia; Davis, Sarah E.; Yau, Christina; Sanil, Ashish; Esserman, Laura J.; Berry, Donald A. 分享 收藏
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