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Lenvatinib plus Pembrolizumab Following Immune Checkpoint Inhibitor Treatment in Patients with Metastatic Clear Cell Renal Cell Carcinoma: Results from Study 111/KEYNOTE-146 仑伐替尼联合帕博利珠单抗在免疫检查点抑制剂治疗后转移性透明细胞肾细胞癌患者中的应用：Study 111/KEYNOTE-146研究的结果 Lee, Chung-Han; Shah, Amishi Yogesh; Rao, Arpit; Taylor, Matthew H.; Di Simone, Christopher; Hsieh, James J.; Pinto, Alvaro; Sarrio, Regina Girones; Cohn, Allen Lee; Bilen, Mehmet Asim; Ribe, Sara Gunnestad; Tennoe, Oyvind Krohn; Richards, Donald; Sweis, Randy F.; Courtright, Jay; Heinrich, Daniel; Perini, Rodolfo; Kubiak, Peter; Bock, Daena; Okpara, Chinyere E. 分享 收藏
Phase Ib/II study of ompenaclid (RGX-202-01), a first-in-class oral inhibitor of the creatine transporter SLC6A8, in combination with FOLFIRI and bevacizumab (BEV) in RAS mutated (RASmt) second-line (2L) advanced/metastatic colorectal cancer (mCRC): Updated results 奥潘奈克立定（RGX-202-01）的Ib/II期研究，奥潘奈克立定是一种首创口服型肌酸转运蛋白SLC6A8抑制剂，该研究联合FOLFIRI和贝伐珠单抗（BEV）用于RAS突变（RASmt）二线（2L）晚期/转移性结直肠癌（mCRC）的更新结果 Hendifar, A.; Gong, J.; Spigel, D. R.; Basu-Mallick, A.; Espinosa, A.; Misleh, J. G.; Richards, D.; Boles, J.; Fakih, M.; Paulson, A. S.; Chung, K.; Cohn, A.; Gupta, M.; Johnson, K.; Bechar, N.; Hoffman, K. A.; Spector, S.; Szarek, M.; Wasserman, R.; Rosen, L. S. 分享 收藏
Modified FOLFOX6 plus bevacizumab with and without nivolumab for first-line treatment of metastatic colorectal cancer: phase 2 results from the CheckMate 9X8 randomized clinical trial Lenz, Heinz-Josef; Parikh, Aparna; Spigel, David R.; Cohn, Allen L.; Yoshino, Takayuki; Kochenderfer, Mark; Elez, Elena; Shao, Spencer H.; Deming, Dustin; Holdridge, Regan; Larson, Timothy; Chen, Eric; Mahipal, Amit; Ucar, Antonio; Cullen, Dana; Baskin-Bey, Edwina; Kang, Tong; Hammell, Amy B.; Yao, Jin; Tabernero, Josep 分享 收藏
Evaluation of potential biomarkers for lenvatinib plus pembrolizumab among patients with advanced endometrial cancer: results from Study 111/KEYNOTE-146 Makker, Vicky; Taylor, Matthew H.; Aghajanian, Carol; Cohn, Allen L.; Brose, Marcia S.; Simone, Christopher Di; Cao, Zhu Alexander; Suttner, Leah; Loboda, Andrey; Cristescu, Razvan; Jelinic, Petar; Orlowski, Robert; Dutta, Lea; Matsui, Junji; Dutcus, Corina E.; Minoshima, Yukinori; Messing, Mark J. 分享 收藏
Phase Ib/II study of ompenaclid (RGX-202-01), afirst-in-class oral inhibitor of the creatine transporter SLC6A8, in combination with FOLFIRI and bevacizumab (BEV) in RAS mutated (RASm) second-line (2L) advanced/metastatic colorectal cancer (mCRC) Hendifar, A.; Spigel, D. R.; Basu-Mallick, A.; Richards, D.; Fakih, M.; Boles, J.; Gupta, M.; Chung, K.; Cohn, A.; Espinosa, A.; Hourdequin, K. C.; Johnson, K.; Michalski, J. M.; Misleh, J. G.; Mukkamala, S.; Paulson, A. S.; Ratnam, S.; Shao, S. H.; Wasserman, R.; Rosen, L. S. 分享 收藏
Regorafenib plus nivolumab in patients with mismatch repair- proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 study Regorafenib联合nivolumab治疗错配修复熟练/微卫星稳定的转移性结直肠癌患者: 一项单臂、开放标签、多中心2期研究 Fakih, Marwan; Raghav, Kanwal Pratap Singh; Chang, David Z.; Larson, Tim; Cohn, Allen L.; Huyck, Timothy K.; Cosgrove, David; Fiorillo, Joseph A.; Tam, Rachel; D'Adamo, David; Sharma, Neelesh; Brennan, Barbara J.; Wang, Ying A.; Coppieters, Sabine; Zebger-Gong, Hong; Weispfenning, Anke; Seidel, Henrik; Ploeger, Bart A.; Mueller, Udo; de Oliveira, Carolina Soares Viana; Paulson, Andrew Scott 分享 收藏
CABOZANTINIB PLUS ATEZOLIZUMAB IN ADVANCED HEAD AND NECK CANCER PREVIOUSLY TREATED WITH PLATINUM-CONTAINING CHEMOTHERAPY: RESULTS FROM COHORT 17 OF THE COSMIC-021 STUDY Rottey, Sylvie; Santoro, Armando; Arnold, Suzanne; Khan, Saad; Cohn, Allen; Fang, Bruno; Andrianova, Svetlana; Sudhagoni, Ramu; Samaraweera, Leleesha; Gonzalez-Cao, Maria 分享 收藏
CSF1 receptor inhibition of tenosynovial giant cell tumor using novel disease-specific MRI measures of tumor burden Peterfy, Charles; Chen, Yan; Countryman, Peter; Chmielowski, Bartosz; Anthony, Stephen P.; Healey, John H.; Wainberg, Zev A.; Cohn, Allen L.; Shapiro, Geoffrey, I; Keedy, Vicki L.; Singh, Arun; Puzanov, Igor; Wagner, Andrew J.; Qian, Meng; Sterba, Mike; Hsu, Henry H.; Tong-Starksen, Sandra; Tap, William D. 分享 收藏
LENVATINIB AND PEMBROLIZUMAB IN ADVANCED ENDOMETRIAL CARCINOMA (EC): LONG-TERM EFFICACY AND SAFETY UPDATE FROM A PHASE 1B/2 STUDY Makker, Vicky; Aghajanian, Carol; Cohn, Allen; Romeo, Margarita; Bratos, Raquel; Brose, Marcia; Messing, Mark; Dutta, Lea; Dutcus, Corina; Huang, Jie; Schmidt, Emmett; Orlowski, Robert; Taylor, Matthew 分享 收藏
Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT Tap, William D.; Singh, Arun S.; Anthony, Stephen Patrick; Sterba, Mike; Zhang, Chao; Healey, John H.; Chmielowski, Bartosz; Cohn, Allen Lee; Shapiro, Geoffrey, I; Keedy, Vicki L.; Wainberg, Zev A.; Puzanov, Igor; Cote, Gregory M.; Wagner, Andrew J.; Braiteh, Fadi; Sherman, Eric; Hsu, Henry H.; Peterfy, Charles; Gelhorn, Heather L.; Ye, Xin; Severson, Paul; West, Brian L.; Lin, Paul S.; Tong-Starksen, Sandra 分享 收藏
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set 使用独立验证集对基于靶向甲基化的多癌症早期检测测试进行临床验证 Klein, E. A.; Richards, D.; Cohn, A.; Tummala, M.; Lapham, R.; Cosgrove, D.; Chung, G.; Clement, J.; Gao, J.; Hunkapiller, N.; Jamshidi, A.; Kurtzman, K. N.; Seiden, M., V; Swanton, C.; Liu, M. C. 分享 收藏
Evaluation of cell-free DNA approaches for multi-cancer early detection 评估用于多种癌症早期检测的游离DNA方法 Liu, M. C.; Jamshidi, A.; Klein, E. A.; Venn, O.; Hubbell, E.; Beausang, J. F.; Zhang, N.; Kurtzman, K. N.; Hou, C.; Richards, D. A.; Yeatman, T. J.; Cohn, A. L.; Thiel, D. D.; Tummala, M. K.; McIntyre, K.; Sekeres, M. A.; Bryce, A. H.; Seiden, M. V.; Swanton, C. 分享 收藏
Association between biomarkers and clinical outcomes of lenvatinib (L) plus pembrolizumab (P) in advanced endometrial cancer (EC): Results from KEYNOTE-146/study 111 Makker, V.; Taylor, M. H.; Aghajanian, C.; Cohn, A. L.; Brose, M. S.; DiSimone, C.; Cao, A.; Suttner, L.; Loboda, A.; Cristescu, R.; Jelinic, P.; Snyder, A.; Nebozhyn, M.; Lunceford, J.; Orlowski, R.; Dutta, L.; Matsui, J.; Dutcus, C.; Minoshima, Y.; Messing, M. 分享 收藏
Efficacy and Safety of Atezolizumab Plus Bevacizumab Following Disease Progression on Atezolizumab or Sunitinib Monotherapy in Patients with Metastatic Renal Cell Carcinoma in IMmotion150: A Randomized Phase 2 Clinical Trial Powles, Thomas; Atkins, Michael B.; Escudier, Bernard; Motzer, Robert J.; Rini, Brian, I; Fong, Lawrence; Joseph, Richard W.; Pal, Sumanta K.; Sznol, Mario; Hainsworth, John; Stadler, Walter M.; Hutson, Thomas E.; Ravaud, Alain; Bracarda, Sergio; Suarez, Cristina; Choueiri, Toni K.; Reeves, James; Cohn, Allen; Ding, Beiying; Leng, Ning; Hashimoto, Kenji; Huseni, Mahrukh; Schiff, Christina; McDermott, David F. 分享 收藏
PROOF: A multicenter, open-label, randomized, phase III trial of infigratinib vs gemcitabine plus cisplatin in patients with advanced cholangiocarcinoma with FGFR2 gene rearrangements Abou-Alfa, G. K.; Borbath, I.; Cohn, A. L.; Goyal, L.; Lamarca, A.; Macarulla, T.; Oh, D-Y.; Roychowdhury, S.; Sadeghi, S.; Shroff, R. T.; Howland, M.; Li, A.; Cho, T.; Pande, A.; Javle, M. 分享 收藏
Infigratinib in patients with advanced cholangiocarcinoma with FGFR2 gene fusions/translocations: the PROOF 301 trial Infigratinib治疗FGFR2基因融合/易位的晚期胆管癌患者: PROOF 301试验 Makawita, Shalini; Abou-Alfa, Ghassan K.; Roychowdhury, Sameek; Sadeghi, Saeed; Borbath, Ivan; Goyal, Lipika; Cohn, Allen; Lamarca, Angela; Oh, Do-Youn; Macarulla, Teresa; Shroff, Rachna T.; Howland, Michael; Li, Ai; Cho, Terry; Pande, Amit; Javle, Milind 分享 收藏
Ramucirumab combined with FOLFOX as front-line therapy for advanced esophageal, gastroesophageal junction, or gastric adenocarcinoma: a randomized, double-blind, multicenter Phase II trial (vol 27, pg 2196, 2016) Ramucirumab联合FOLFOX作为晚期食管，胃食管交界处或胃腺癌的一线治疗: 一项随机，双盲，多中心II期试验 (第27卷，2196页，2016) Yoon, H. H.; Bendell, J. C.; Braiteh, F. S.; Firdaus, I.; Philip, P. A.; Cohn, A. L.; Lewis, N.; Anderson, D. M.; Arrowsmith, E.; Schwartz, J. D.; Gao, L.; Hsu, Y.; Xu, Y.; Ferry, D.; Alberts, S. R.; Wainberg, Z. A. 分享 收藏
33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018) (vol 6, pg 115, 2018) Berry, Sneha; Giraldo, Nicolas; Nguyen, Peter; Green, Benjamin; Xu, Haiying; Ogurtsova, Aleksandra; Soni, Abha; Succaria, Farah; Wang, Daphne; Roberts, Charles; Stein, Julie; Engle, Elizabeth; Pardoll, Drew; Anders, Robert; Cottrell, Tricia; Taube, Janis M.; Tran, Ben; Voskoboynik, Mark; Kuo, James; Bang, Yung-Lue; Chung, Hyun-Cheo; Ahn, Myung-Ju; Kim, Sang-We; Perera, Ayesh; Freeman, Daniel; Achour, Ikbel; Faggioni, Raffaella; Xiao, Feng; Ferte, Charles; Lemech, Charlotte; Meric-Bernstam, Funda; Werner, Theresa; Hodi, Stephen; Messersmith, Wells; Lewis, Nancy; Talluto, Craig; Dostalek, Mirek; Tao, Aiyang; McWhirter, Sarah; Trujillo, Damian; Luke, Jason; Xu, Chunxiao; BoMarelli; Qi, Jin; Qin, Guozhong; Yu, Huakui; Jenkins, Molly; Lo, Kin-Ming; Halle, Joern-Peter; Lan, Yan; Taylor, Matthew; Vogelzang, Nicholas; Cohn, Allen; Stepan, Daniel; Shumaker, Robert; Dutcus, Corina; Guo, Matthew; Schmidt, Emmett; Rasco, Drew; Brose, Marcia; Vogelzang, Nicholas; Simone, Christopher Di; Jain, Sharad; Richards, Donald; Encarnacion, Carlos; Rasco, Drew; Shumaker, Robert; Dutcus, Corina; Stepan, Daniel; Guo, Matthew; Schmidt, Emmett; Taylor, Matthew; Vogelzang, Nicholas; Encarnacion, Carlos; Cohn, Allen; Di Simone, Christopher; Rasco, Drew; Richards, Donald; Taylor, Matthew; Dutcus, Corina; Stepan, Daniel; Shumaker, Robert; Guo, Matthew; Schmidt, Emmett; Mier, James; An, Jeongshin; Yang, Yeun-yeoul; Lee, Won-Hee; Yang, Jinho; Kim, Jong-kyu; Kim, Hyun Goo; Paek, Se Hyun; Lee, Jun Woo; Woo, Joohyun; Kim, Jong Bin; Kwon, Hyungju; Lim, Woosung; Paik, Nam Sun; Kim, Yoon-Keun; Moon, Byung-In; Janku, Filip; Tan, David; Martin-Liberal, Juan; Takahashi, Shunji; Geva, Ravit; Gucalp, Ayca; Chen, Xueying; Subramanian, Kulandayan; Mataraza, Jennifer; Wheler, Jennifer; Bedard, Philippe 分享 收藏
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