Alexander Sumaroka - Publications, H-index & Citations

Alexander Sumaroka

university of pennsylvania

51H指数

210论文数

8.9K被引数

收录论文 75

发表时间

Recovery of cone-mediated vision in Lebercilin associated retinal ciliopathy after gene therapy: One-year results of a phase I/II trial 72. Aleman TS, Uyhazi KE, Roman AJ, 等. 基因疗法在Lebercilin相关视网膜纤毛病中恢复视锥介导视力的研究：一项I/II期试验的一年结果。Mol Ther 2025:S1525;

Molecular Therapy

IF12

2025-07-01

PREAI

Tomas S. Aleman; Katherine E. Uyhazi; Alejandro J. Roman; Mariejel L. Weber; Erin C. O’Neil; Malgorzata Swider; Alexander Sumaroka; Katherine H. Maguire; Elena M. Aleman; Arlene J. Santos; Rebecca J. Kim; Kelsey M. Parchinski; Andrew Billek; Makayla Fradin; William Chung; Paris Margaritis; Junwei Sun; Drew H. Scoles; Vivian Wu; Alexandra V. Garafalo; Ashwath Jayagopal; Ben Yerxa; Sarah Tuller; Albert M. Maguire; Jean Bennett; Artur V. Cideciyan

Retinal Degeneration Associated With Biallelic RDH12 Variants: Longitudinal Evaluation of Retinal Structure and Visual Function in Pediatric Patients

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2024-12-18

OAAI

Aleman, Tomas S.; Roman, Alejandro J.; Uyhazi, Katherine E.; Jiang, Yu You; Bedoukian, Emma C.; Sumaroka, Alexander; Wu, Vivian; Swider, Malgorzata; Viarbitskaya, Iryna; Russell, Robert C.; Shagena, Elizabeth O.; Santos, Arlene J.; Serrano, Leona W.; Parchinski, Kelsey M.; Kim, Rebecca J.; Weber, Mariejel L.; Garafalo, Alexandra, V; Thompson, Dorothy A.; Maguire, Albert M.; Bennett, Jean; Scoles, Drew H.; O'Neil, Erin C.; Morgan, Jessica I. W.; Cideciyan, Artur, V

Safety and improved efficacy signals following gene therapy in childhood blindness caused by GUCY2D mutations (vol 24, 102409, 2021)GUCY2D基因突变导致的儿童失明在基因疗法后显示出安全性和疗效改善的信号（卷24，102409，2021）

ISCIENCE

IF4.1

2024-11-01

OAAI

Jacobson, Samuel G.; Cideciyan, Artur, V; Ho, Allen C.; Peshenko, Igor, V; Garafalo, Alexandra, V; Roman, Alejandro J.; Sumaroka, Alexander; Wu, Vivian; Krishnan, Arun K.; Sheplock, Rebecca; Cheang, Bee-Lin; Davidson, Vanessa; O'Riordan, Catherine R.; Boye, Sanford L.; Dizhoor, Alexander M.; Boye, Shannon E.

Retinal prolactin isoform PRLΔE1 sustains rod disease in inherited retinal degenerations

CELL DEATH & DISEASE

IF9.6

2024-09-18

OAAI

Sudharsan, Raghavi; Kwok, Jennifer; Swider, Malgorzata; Sumaroka, Alexander; Aguirre, Gustavo D.; Cideciyan, Artur V.; Beltran, William A.

Treatment Strategy With Gene Editing for Late-Onset Retinal Degeneration Caused by a Founder Variant in C1QTNF5

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2023-12-22

OAAI

Li, Randa T. H.; Roman, Alejandro J.; Sumaroka, Alexander; Stanton, Chloe M.; Swider, Malgorzata; Garafalo, Alexandra V.; Heon, Elise; Vincent, Ajoy; Wright, Alan F.; Megaw, Roly; Aleman, Tomas S.; Browning, Andrew C.; Dhillon, Baljean; Cideciyan, Artur V.

Photoreceptor Function and Structure in Autosomal Dominant Vitelliform Macular Dystrophy Caused by BEST1 Mutations

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2022-12-13

OAAI

Cideciyan, Artur V.; Jacobson, Samuel G.; Swider, Malgorzata; Sumaroka, Alexander; Sheplock, Rebecca; Krishnan, Arun K.; Garafalo, Alexandra V.; Guziewicz, Karina E.; Aguirre, Gustavo D.; Beltran, William A.; Heon, Elise

Restoration of Cone Sensitivity to Individuals with Congenital Photoreceptor Blindness within the Phase 1/2 Sepofarsen Trial

OPHTHALMOLOGY SCIENCE

IF4.6

2022-06-01

OAAI

Cideciyan, Artur, V; Jacobson, Samuel G.; Ho, Allen C.; Krishnan, Arun K.; Roman, Alejandro J.; Garafalo, Alexandra, V; Wu, Vivian; Swider, Malgorzata; Sumaroka, Alexander; Van Cauwenbergh, Caroline; Russell, Stephen R.; Drack, Arlene, V; Leroy, Bart P.; Schwartz, Michael R.; Girach, Aniz

Intravitreal antisense oligonucleotide sepofarsen in Leber congenital amaurosis type 10: a phase 1b/2 trial

NATURE MEDICINE

IF50

2022-04-04

OAAI

Russell, Stephen R.; Drack, Arlene, V; Cideciyan, Artur, V; Jacobson, Samuel G.; Leroy, Bart P.; Van Cauwenbergh, Caroline; Ho, Allen C.; Dumitrescu, Alina, V; Han, Ian C.; Martin, Mitchell; Pfeifer, Wanda L.; Sohn, Elliott H.; Walshire, Jean; Garafalo, Alexandra, V; Krishnan, Arun K.; Powers, Christian A.; Sumaroka, Alexander; Roman, Alejandro J.; Vanhonsebrouck, Eva; Jones, Eltanara; Nerinckx, Fanny; De Zaeytijd, Julie; Collin, Rob W. J.; Hoyng, Carel; Adamson, Peter; Cheetham, Michael E.; Schwartz, Michael R.; den Hollander, Wilhelmina; Asmus, Friedrich; Platenburg, Gerard; Rodman, David; Girach, Aniz

Measures of Function and Structure to Determine Phenotypic Features, Natural History, and Treatment Outcomes in Inherited Retinal Diseases

ANNUAL REVIEW OF VISION SCIENCE, VOL 7, 2021

IF0

2021-09-15

OAAI

Cideciyan, Artur V.; Krishnan, Arun K.; Roman, Alejandro J.; Sumaroka, Alexander; Swider, Malgorzata; Jacobson, Samuel G.

Durable vision improvement after a single treatment with antisense oligonucleotide sepofarsen: a case report

NATURE MEDICINE

IF50

2021-04-01

OAAI

Cideciyan, Artur V.; Jacobson, Samuel G.; Ho, Allen C.; Garafalo, Alexandra V.; Roman, Alejandro J.; Sumaroka, Alexander; Krishnan, Arun K.; Swider, Malgorzata; Schwartz, Michael R.; Girach, Aniz

Childhood-onset genetic cone-rod photoreceptor diseases and underlying pathobiology

EBIOMEDICINE

IF10.8

2021-01-01

OAAI

Garafalo, Alexandra V.; Sheplock, Rebecca; Sumaroka, Alexander; Roman, Alejandro J.; Cideciyan, Artur V.; Jacobson, Samuel G.

Foveal Therapy in Blue Cone Monochromacy: Predictions of Visual Potential From Artificial Intelligence

FRONTIERS IN NEUROSCIENCE

IF3.2

2020-08-03

OAAI

Sumaroka, Alexander; Cideciyan, Artur V.; Sheplock, Rebecca; Wu, Vivian; Kohl, Susanne; Wissinger, Bernd; Jacobson, Samuel G.

Rod function deficit in retained photoreceptors of patients with class B Rhodopsin mutations

SCIENTIFIC REPORTS

IF3.9

2020-07-28

OAAI

Cideciyan, Artur, V; Jacobson, Samuel G.; Roman, Alejandro J.; Sumaroka, Alexander; Wu, Vivian; Charng, Jason; Lisi, Brianna; Swider, Malgorzata; Aguirre, Gustavo D.; Beltran, William A.

Progress in treating inherited retinal diseases: Early subretinal gene therapy clinical trials and candidates for future initiatives

PROGRESS IN RETINAL AND EYE RESEARCH

IF14.7

2020-07-01

128

OAAI

Garafalo, Alexandra, V; Cideciyan, Artur, V; Heon, Elise; Sheplock, Rebecca; Pearson, Alexander; Yu, Caberry WeiYang; Sumaroka, Alexander; Aguirre, Gustavo D.; Jacobson, Samuel G.

Long-Term Structural Outcomes of Late-Stage RPE65 Gene Therapy

MOLECULAR THERAPY

IF12

2020-01-01

OAAI

Gardiner, Kristin L.; Cideciyan, Artur V.; Swider, Malgorzata; Dufour, Valerie L.; Sumaroka, Alexander; Komaromy, Andras M.; Hauswirth, William W.; Iwabe, Simone; Jacobson, Samuel G.; Beltran, William A.; Aguirre, Gustavo D.

Treatment Potential for Macular Cone Vision in Leber Congenital Amaurosis Due to CEP290 or NPHP5 Mutations: Predictions From Artificial Intelligence

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2019-06-18

OAAI

Sumaroka, Alexander; Garafalo, Alexandra V.; Semenov, Evelyn P.; Sheplock, Rebecca; Krishnan, Arun K.; Roman, Alejandro J.; Jacobson, Samuel G.; Cideciyan, Artur V.

A G86R mutation in the calcium-sensor protein GCAP1 alters regulation of retinal guanylyl cyclase and causes dominant cone-rod degeneration

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-03-01

OAAI

Peshenko, Igor V.; Cideciyan, Artur V.; Sumaroka, Alexander; Olshevskaya, Elena V.; Scholten, Alexander; Abbas, Seher; Koch, Karl-Wilhelm; Jacobson, Samuel G.; Dizhoor, Alexander M.

Effect of an intravitreal antisense oligonucleotide on vision in Leber congenital amaurosis due to a photoreceptor cilium defect

NATURE MEDICINE

IF50

2018-12-17

167

PREAI

Cideciyan, Artur V.; Jacobson, Samuel G.; Drack, Arlene V.; Ho, Allen C.; Charng, Jason; Garafalo, Alexandra V.; Roman, Alejandro J.; Sumaroka, Alexander; Han, Ian C.; Hochstedler, Maria D.; Pfeifer, Wanda L.; Sohn, Elliott H.; Taiel, Magali; Schwartz, Michael R.; Biasutto, Patricia; de Wit, Wilma; Cheetham, Michael E.; Adamson, Peter; Rodman, David M.; Platenburg, Gerard; Tome, Maria D.; Balikova, Irina; Nerinckx, Fanny; De Zaeytijd, Julie; Van Cauwenbergh, Caroline; Leroy, Bart P.; Russell, Stephen R.

Blue Cone Monochromacy Caused by the C203R Missense Mutation or Large Deletion Mutations

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2018-12-05

OAAI

Sumaroka, Alexander; Garafalo, Alexandra V.; Cideciyan, Artur V.; Charng, Jason; Roman, Alejandro J.; Choi, Windy; Saxena, Supna; Aksianiuk, Valeryia; Kohl, Susanne; Wissinger, Bernd; Jacobson, Samuel G.

Variegated yet non-random rod and cone photoreceptor disease patterns in RPGR-ORF15-associated retinal degeneration (vol 25, pg 5444, 2016)

HUMAN MOLECULAR GENETICS

IF3.2

2018-10-04

OAAI

Charng, Jason; Cideciyan, Artur V.; Jacobson, Samuel G.; Sumaroka, Alexander; Schwartz, Sharon B.; Swider, Malgorzata; Roman, Alejandro J.; Sheplock, Rebecca; Anand, Manisha; Peden, Marc C.; Khanna, Hemant; Heon, Elise; Wright, Alan F.; Swaroop, Anand

研究方向