未登录 The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression Xiao, GH; Gallagher, R; Shetler, J; Skele, K; Altomare, DA; Pestell, RG; Jhanwar, S; Testa, JR 分享 收藏
Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma RIPK3的体细胞表观遗传沉默可灭活坏死性凋亡并有助于恶性间皮瘤的化学抗性 Tan, Yinfei; Sementino, Eleonora; Cheung, Mitchell; Peri, Suraj; Menges, Craig W.; Kukuyan, Anna-Mariya; Zhang, Ting; Khazak, Vladimir; Fox, Lauren A.; Ross, Eric A.; Ramanathan, Suresh; Jhanwar, Suresh C.; Flores, Raja M.; Balachandran, Siddharth; Testa, Joseph R. 分享 收藏
SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells Xu, Xiaoliang L.; Li, Zhengke; Liu, Aihong; Fan, Xianqun; Hu, Dan-ning; Qi, Dong-Lai; Chitty, David W.; Jia, Renbing; Qui, Jianping; Wang, Justin Q.; Sharaf, Jake; Zou, Jun; Weiss, Rebecca; Huang, Hongyan; Joseph, Walter J.; Ng, Lily; Rosen, Richard; Shen, Binghui; Reid, Mark W.; Forrest, Douglas; Abramson, David H.; Singer, Samuel; Cobrinik, David; Jhanwar, Suresh C. 分享 收藏
NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition Garcia-Rendueles, Maria E. R.; Ricarte-Filho, Julio C.; Untch, Brian R.; Landa, Inigo; Knauf, Jeffrey A.; Voza, Francesca; Smith, Vicki E.; Ganly, Ian; Taylor, Barry S.; Persaud, Yogindra; Oler, Gisele; Fang, Yuqiang; Jhanwar, Suresh C.; Viale, Agnes; Heguy, Adriana; Huberman, Kety H.; Giancotti, Filippo; Ghossein, Ronald; Fagin, James A. 分享 收藏
Overexpression of E2F1 in lung and liver metastases of human colon cancer is associated with gene amplification Iwamoto, M; Banerjee, D; Menon, LG; Jurkiewicz, A; Rao, PH; Kemeny, NE; Fong, YM; Jhanwar, SC; Gorlick, R; Bertino, JR 分享 收藏
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A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia Shah, Sohela; Schrader, Kasmintan A.; Waanders, Esme; Timms, Andrew E.; Vijai, Joseph; Miething, Cornelius; Wechsler, Jeremy; Yang, Jun; Hayes, James; Klein, Robert J.; Zhang, Jinghui; Wei, Lei; Wu, Gang; Rusch, Michael; Nagahawatte, Panduka; Ma, Jing; Chen, Shann-Ching; Song, Guangchun; Cheng, Jinjun; Meyers, Paul; Bhojwani, Deepa; Jhanwar, Suresh; Maslak, Peter; Fleisher, Martin; Littman, Jason; Offit, Lily; Rau-Murthy, Rohini; Fleischut, Megan Harlan; Corines, Marina; Murali, Rajmohan; Gao, Xiaoni; Manschreck, Christopher; Kitzing, Thomas; Murty, Vundavalli V.; Raimondi, Susana C.; Kuiper, Roland P.; Simons, Annet; Schiffman, Joshua D.; Onel, Kenan; Plon, Sharon E.; Wheeler, David A.; Ritter, Deborah; Ziegler, David S.; Tucker, Kathy; Sutton, Rosemary; Chenevix-Trench, Georgia; Li, Jun; Huntsman, David G.; Hansford, Samantha; Senz, Janine; Walsh, Tom; Lee, Ming; Hahn, Christopher N.; Roberts, Kathryn G.; King, Mary-Claire; Lo, Sarah M.; Levine, Ross L.; Viale, Agnes; Socci, Nicholas D.; Nathanson, Katherine L.; Scott, Hamish S.; Daly, Mark; Lipkin, Steven M.; Lowe, Scott W.; Downing, James R.; Altshuler, David; Sandlund, John T.; Horwitz, Marshall S.; Mullighan, Charles G.; Offit, Kenneth 分享 收藏
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IDH Mutation and Neuroglial Developmental Features Define Clinically Distinct Subclasses of Lower Grade Diffuse Astrocytic Glioma Gorovets, Daniel; Kannan, Kasthuri; Shen, Ronglai; Kastenhuber, Edward R.; Islamdoust, Nasrin; Campos, Carl; Pentsova, Elena; Heguy, Adriana; Jhanwar, Suresh C.; Mellinghoff, Ingo K.; Chan, Timothy A.; Huse, Jason T. 分享 收藏
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response Szerlip, Nicholas J.; Pedraza, Alicia; Chakravarty, Debyani; Azim, Mohammad; McGuire, Jeremy; Fang, Yuqiang; Ozawa, Tatsuya; Holland, Eric C.; Huse, Jason T.; Jhanwar, Suresh; Leversha, Margaret A.; Mikkelsen, Tom; Brennan, Cameron W. 分享 收藏
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Crizotinib in ALK-Rearranged Inflammatory Myofibroblastic Tumor Butrynski, James E.; D'Adamo, David R.; Hornick, Jason L.; Dal Cin, Paola; Antonescu, Cristina R.; Jhanwar, Suresh C.; Ladanyi, Marc; Capelletti, Marzia; Rodig, Scott J.; Ramaiya, Nikhil; Kwak, Eunice L.; Clark, Jeffrey W.; Wilner, Keith D.; Christensen, James G.; Jaenne, Pasi A.; Maki, Robert G.; Demetri, George D.; Shapiro, Geoffrey I. 分享 收藏
Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer Janakiraman, Manickam; Vakiani, Efsevia; Zeng, Zhaoshi; Pratilas, Christine A.; Taylor, Barry S.; Chitale, Dhananjay; Halilovic, Ensar; Wilson, Manda; Huberman, Kety; Ricarte Filho, Julio Cezar; Persaud, Yogindra; Levine, Douglas A.; Fagin, James A.; Jhanwar, Suresh C.; Mariadason, John M.; Lash, Alex; Ladanyi, Marc; Saltz, Leonard B.; Heguy, Adriana; Paty, Philip B.; Solit, David B. 分享 收藏
Feasibility of ex Vivo FDG PET of the Colon Gollub, Marc J.; Akhurst, Timothy J.; Williamson, Matthew J.; Shia, Jinru; Humm, John L.; Wong, W. Douglas; Paty, Philip B.; Guillem, Jose G.; Weiser, Martin R.; Temple, Larissa K. F.; Dauer, Lawrence T.; Jhanwar, Suresh C.; Kronman, Rachel E.; Montalvo, Carolina V.; Miller, Allison R.; Larson, Steven M.; Margulis, Alexander R. 分享 收藏
A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-Cell lymphomas from Lck-Akt2 transgenic mice Tan, Yinfei; Timakhov, Roman A.; Rao, Mamta; Altomare, Deborah A.; Xu, Jinfei; Liu, Zemin; Gao, Qingshen; Jhanwar, Suresh C.; Di Cristofano, Antonio; Wiest, David L.; Knepper, Janice E.; Testa, Joseph R. 分享 收藏
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Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth Altomare, DA; You, HH; Xiao, GH; Ramos-Nino, ME; Skele, KL; De Rienzo, A; Jhanwar, SC; Mossman, BT; Kane, AB; Testa, JR 分享 收藏
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