未登录 SF3B1 mutation accelerates the development of CLL via activation of the mTOR pathway SF3B1突变通过激活mTOR通路加速CLL的发展。 Zhang, Bo; Iyer, Prajish; Jin, Meiling; Ten Hacken, Elisa; Cartun, Zachary J.; Hart, Kevyn L.; Fernandez, Mike; Stevenson, Kristen; Rassenti, Laura; Ghia, Emanuela M.; Kipps, Thomas J.; Neuberg, Donna; Carrasco, Ruben; Chan, Wing C.; Song, Joo Y.; Hu, Yu; Wu, Catherine J.; Wang, Lili 分享 收藏
The Impact of Therapeutic Selective Pressure on the Evolutionary Landscape of Chronic Lymphocytic Leukemia 治疗性选择性压力对慢性淋巴细胞白血病进化景观的影响 Karisani, Negin; Sud, Amit; Li, Liang; Gohil, Satyen; Schlueter-Kuck, Kristy; Rassenti, Laura; Tran, Tuan N.; Cheung, Leo Wang-Kit; Szafer-Glusman, Iliana Edith; Dean, James P.; Chen, Guang; Tsuji, Junko; Kay, Neil E.; Rai, Kanti R.; Brown, Jennifer R.; Gribben, John G.; Gribben, John C.; Byrd, John C.; Neuberg, Donna S.; Stewart, Chip; Bozic, Ivana; Kipps, Thomas J.; Getz, Gad; Wu, Catherine J. 分享 收藏
a phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic HER2-negative breast cancer (vol 26, 32, 2024) Shatsky, Rebecca A.; Batra-Sharma, Hemali; Helsten, Teresa; Schwab, Richard B.; Pittman, Emily I.; Pu, Minya; Weihe, Elizabeth; Ghia, Emanuela M.; Rassenti, Laura Z.; Molinolo, Alfredo; Cabrera, Betty; Breitmeyer, James B.; Widhopf II, George F.; Messer, Karen; Jamieson, Catriona; Kipps, Thomas J.; Parker, Barbara A. 分享 收藏
A phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic Her2-negative breast cancer zilovertamab联合紫杉醇治疗局部晚期/不可切除或转移性Her2-negative乳腺癌的1b期研究 Shatsky, Rebecca A.; Batra-Sharma, Hemali; Helsten, Teresa; Schwab, Richard B.; Pittman, Emily I.; Pu, Minya; Weihe, Elizabeth; Ghia, Emanuela M.; Rassenti, Laura Z.; Molinolo, Alfredo; Cabrera, Betty; Breitmeyer, James B.; Widhopf II, George F.; Messer, Karen; Jamieson, Catriona; Kipps, Thomas J.; Parker, Barbara A. 分享 收藏
Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia 人内源性逆转录病毒在慢性淋巴细胞白血病中的表达特征 La Ferlita, Alessandro; Nigita, Giovanni; Tsyba, Liudmyla; Palamarchuk, Alexey; Alaimo, Salvatore; Pulvirenti, Alfredo; Balatti, Veronica; Rassenti, Laura; Tsichlis, Philip N.; Kipps, Thomas; Pekarsky, Yuri; Croce, Carlo M. 分享 收藏
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome 慢性淋巴细胞白血病向Richter综合征转化的进化史 Parry, Erin M.; Leshchiner, Ignaty; Guieze, Romain; Johnson, Connor; Tausch, Eugen; Parikh, Sameer A.; Lemvigh, Camilla; Broseus, Julien; Hergalant, Sebastien; Messer, Conor; Utro, Filippo; Levovitz, Chaya; Rhrissorrakrai, Kahn; Li, Liang; Rosebrock, Daniel; Yin, Shanye; Deng, Stephanie; Slowik, Kara; Jacobs, Raquel; Huang, Teddy; Li, Shuqiang; Fell, Geoff; Redd, Robert; Lin, Ziao; Knisbacher, Binyamin A.; Livitz, Dimitri; Schneider, Christof; Ruthen, Neil; Elagina, Liudmila; Taylor-Weiner, Amaro; Persaud, Bria; Martinez, Aina; Fernandes, Stacey M.; Purroy, Noelia; Anandappa, Annabelle J.; Ma, Jialin; Hess, Julian; Rassenti, Laura Z.; Kipps, Thomas J.; Jain, Nitin; Wierda, William; Cymbalista, Florence; Feugier, Pierre; Kay, Neil E.; Livak, Kenneth J.; Danysh, Brian P.; Stewart, Chip; Neuberg, Donna; Davids, Matthew S.; Brown, Jennifer R.; Parida, Laxmi; Stilgenbauer, Stephan; Getz, Gad; Wu, Catherine J. J. 分享 收藏
Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia Kaufman, Matthew; Yan, Xiao-Jie; Li, Wentian; Ghia, Emanuela M.; Langerak, Anton W.; Rassenti, Laura Z.; Belessi, Chrysoula; Kay, Neil E.; Davi, Frederic; Byrd, John C.; Pospisilova, Sarka; Brown, Jennifer R.; Catherwood, Mark; Davis, Zadie; Oscier, David; Montillo, Marco; Trentin, Livio; Rosenquist, Richard; Ghia, Paolo; Barrientos, Jacqueline C.; Kolitz, Jonathan E.; Allen, Steven L.; Rai, Kanti R.; Stamatopoulos, Kostas; Kipps, Thomas J.; Neuberg, Donna; Chiorazzi, Nicholas 分享 收藏
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cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies Pedersen, Christina Bligaard; Dam, Soren Helweg; Barnkob, Mike Bogetofte; Leipold, Michael D.; Purroy, Noelia; Rassenti, Laura Z.; Kipps, Thomas J.; Nguyen, Jennifer; Lederer, James Arthur; Gohil, Satyen Harish; Wu, Catherine J.; Olsen, Lars Ronn 分享 收藏
A large fraction of trisomy 12, 17p-, and 11q- CLL cases carry unidentified microdeletions of miR-15a/16-1 大部分三体性12、17p-和11q-cll病例携带未鉴定的miR-15a/16-1微缺失 Pepe, Felice; Rassenti, Laura Z.; Pekarsky, Yuri; Labanowska, Jadwiga; Nakamura, Tatsuya; Nigita, Giovanni; Kipps, Thomas J.; Balatti, Veronica; Croce, Carlo M. 分享 收藏
Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia Biran, Anat; Yin, Shanye; Kretzmer, Helene; ten Hacken, Elisa; Parvin, Salma; Lucas, Fabienne; Uduman, Mohamed; Gutierrez, Catherine; Dangle, Nathan; Billington, Leah; Regis, Fara Faye; Rassenti, Laura Z.; Mohammad, Arman; Hoffmann, Gabriela Brunsting; Stevenson, Kristen; Zheng, Mei; Witten, Elizabeth; Fernandes, Stacey M.; Tausch, Eugen; Sun, Clare; Stilgenbauer, Stephan; Brown, Jennifer R.; Kipps, Thomas J.; Aster, John C.; Gnirke, Andreas; Neuberg, Donna S.; Letai, Anthony; Wang, Lili; Carrasco, Ruben D.; Meissner, Alexander; Wu, Catherine J. 分享 收藏
Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History Penter, Livius; Gohil, Satyen H.; Lareau, Caleb; Ludwig, Leif S.; Parry, Erin M.; Huang, Teddy; Li, Shuqiang; Zhang, Wandi; Livitz, Dimitri; Leshchiner, Ignaty; Parida, Laxmi; Getz, Gad; Rassenti, Laura Z.; Kipps, Thomas J.; Brown, Jennifer R.; Davids, Matthew S.; Neuberg, Donna S.; Livak, Kenneth J.; Sankaran, Vijay G.; Wu, Catherine J. 分享 收藏
Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans Kleinstern, Geffen; Weinberg, J. Brice; Parikh, Sameer A.; Braggio, Esteban; Achenbach, Sara J.; Robinson, Dennis P.; Norman, Aaron D.; Rabe, Kari G.; Boddicker, Nicholas J.; Vachon, Celine M.; Lesnick, Connie E.; Call, Timothy G.; Brander, Danielle M.; Rassenti, Laura Z.; Kipps, Thomas J.; Olson, Janet E.; Cerhan, James R.; Kay, Neil E.; Furman, Richard R.; Hanson, Curtis A.; Shanafelt, Tait D.; Slager, Susan L. 分享 收藏
Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment Gutierrez, Catherine; Al'Khafaji, Aziz M.; Brenner, Eric; Johnson, Kaitlyn E.; Gohil, Satyen H.; Lin, Ziao; Knisbacher, Binyamin A.; Durrett, Russell E.; Li, Shuqiang; Parvin, Salma; Biran, Anat; Zhang, Wandi; Rassenti, Laura; Kipps, Thomas J.; Livak, Kenneth J.; Neuberg, Donna; Letai, Anthony; Getz, Gad; Wu, Catherine J.; Brock, Amy 分享 收藏
Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia 复发性XPO1突变改变慢性淋巴细胞白血病的发病机制 Walker, Janek S.; Hing, Zachary A.; Harrington, Bonnie; Baumhardt, Jordan; Ozer, Hatice Gulcin; Lehman, Amy; Giacopelli, Brian; Beaver, Larry; Williams, Katie; Skinner, Jordan N.; Cempre, Casey B.; Sun, Qingxiang; Shacham, Sharon; Stromberg, Benjamin R.; Summers, Matthew K.; Abruzzo, Lynne, V; Rassenti, Laura; Kipps, Thomas J.; Parikh, Sameer; Kay, Neil E.; Rogers, Kerry A.; Woyach, Jennifer A.; Coppola, Vincenzo; Chook, Yuh Min; Oakes, Christopher; Byrd, John C.; Lapalombella, Rosa 分享 收藏
Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy Kretzmer, Helene; Biran, Anat; Purroy, Noelia; Lemvigh, Camilla K.; Clement, Kendell; Gruber, Michaela; Gu, Hongcang; Rassenti, Laura; Mohammad, Arman W.; Lesnick, Connie; Slager, Susan L.; Braggio, Esteban; Shanafelt, Tait D.; Kay, Neil E.; Fernandes, Stacey M.; Brown, Jennifer R.; Wang, Lili; Li, Shuqiang; Livak, Kenneth J.; Neuberg, Donna S.; Klages, Sven; Timmermann, Bernd; Kipps, Thomas J.; Campo, Elias; Gnirke, Andreas; Wu, Catherine J.; Meissner, Alexander 分享 收藏
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Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect Bachireddy, Pavan; Ennis, Christina; Nguyen, Vinhkhang N.; Gohil, Satyen H.; Clement, Kendell; Shukla, Sachet A.; Forman, Juliet; Barkas, Nikolaos; Freeman, Samuel; Bavli, Natalie; Elagina, Liudmila; Leshchiner, Ignaty; Mohammad, Arman W.; Mathewson, Nathan D.; Keskin, Derin B.; Rassenti, Laura Z.; Kipps, Thomas J.; Brown, Jennifer R.; Getz, Gad; Ho, Vincent T.; Gnirke, Andreas; Neuberg, Donna; Soiffer, Robert J.; Ritz, Jerome; Alyea, Edwin P.; Kharchenko, Peter, V; Wu, Catherine J. 分享 收藏
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