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The co-receptor Neuropilin-1 enhances proliferation in inv(16) acute myeloid leukemia via VEGF signaling Hegde, Mahesh; Ahmad, Mohd H.; Lazaro, Roger Mulet; Sugita, Mayumi; Li, Rui; Hu, Kai; Gebhard, Claudia; Guzman, Monica L.; Bushweller, John H.; Zhu, Lihua J.; Brehm, Michael; Wolfe, Scot A.; Delwel, Ruud; Castilla, Lucio H. 分享 收藏
STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia Fischer, Alexander; Hernandez-Rodriguez, Benjamin; Mulet-Lazaro, Roger; Nuetzel, Margit; Hoelzl, Fabian; van Herk, Stanley; Kavelaars, Francois G.; Stanewsky, Hanna; Ackermann, Ute; Niang, Amadou H.; Diaz, Noelia; Reuschel, Edith; Strieder, Nicholas; Hernandez-Lopez, Inmaculada; Valk, Peter J. M.; Vaquerizas, Juan M.; Rehli, Michael; Delwel, Ruud; Gebhard, Claudia 分享 收藏
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Transcriptional repression of the neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein Yang, GY; Khalaf, W; van de Locht, L; Jansen, JH; Gao, MH; Thompson, MA; van der Reijden, BA; Gutmann, DH; Delwel, R; Clapp, DW; Hiebert, SW 分享 收藏
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency Rein, Avigail; Geron, Ifat; Kugler, Eitan; Fishman, Hila; Gottlieb, Eyal; Abramovich, Ifat; Giladi, Amir; Amit, Ido; Mulet-Lazaro, Roger; Delwel, Ruud; Groeschel, Stefan; Levin-Zaidman, Smadar; Dezorella, Nili; Holdengreber, Vered; Rao, Tata Nageswara; Yacobovich, Joanne; Steinberg-Shemer, Orna; Huang, Qiu-Hua; Tan, Yun; Chen, Sai-Juan; Izraeli, Shai; Birger, Yehudit 分享 收藏
Induced cell-autonomous neutropenia systemically perturbs hematopoiesis in Cebpa enhancer-null mice Avellino, Roberto; Mulet-Lazaro, Roger; Havermans, Marije; Hoogenboezem, Remco; Smeenk, Leonie; Salomonis, Nathan; Schneider, Rebekka K.; Rombouts, Elwin; Bindels, Eric; Grimes, Lee; Delwel, Ruud 分享 收藏
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops 白血病癌基因EVI1通过CTCF促进的环劫持MYC超级增强子 Ottema, Sophie; Mulet-Lazaro, Roger; Erpelinck-Verschueren, Claudia; van Herk, Stanley; Havermans, Marije; Varea, Andrea Arricibita; Vermeulen, Michael; Beverloo, H. Berna; Groeschel, Stefan; Haferlach, Torsten; Haferlach, Claudia; Wouters, Bas J.; Bindels, Eric; Smeenk, Leonie; Delwel, Ruud 分享 收藏
Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia Smeenk, Leonie; Ottema, Sophie; Mulet-Lazaro, Roger; Ebert, Anja; Havermans, Marije; Varea, Andrea Arricibita; Fellner, Michaela; Pastoors, Dorien; van Herk, Stanley; Erpelinck-Verschueren, Claudia; Grob, Tim; Hoogenboezem, Remco M.; Kavelaars, Francois G.; Matson, Daniel R.; Bresnick, Emery H.; Bindels, Eric M.; Kentsis, Alex; Zuber, Johannes; Delwel, Ruud 分享 收藏
Derepression of retroelements in acute myeloid leukemia with 3q aberrations Mika, Jagoda; Ottema, Sophie; Kiehlmeier, Sandra; Kruse, Sabrina; Smeenk, Leonie; Mueller, Judith; Schweiggert, Sabrina; Herrmann, Carl; Sanders, Mathijs; Delwel, Ruud; Groeschel, Stefan 分享 收藏
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML Li, Sheng; Chen, Xiaowen; Wang, Jiahui; Meydan, Cem; Glass, Jacob L.; Shih, Alan H.; Delwel, Ruud; Levine, Ross L.; Mason, Christopher E.; Melnick, Ari M. 分享 收藏
RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction (vol 28, pg 3022, 2019) Ptasinska, Anetta; Pickin, Anna; Assi, Salam A.; Chin, Paulynn Suyin; Ames, Luke; Avellino, Roberto; Groschel, Stefan; Delwel, Ruud; Cockerill, Peter N.; Osborne, Cameron S.; Bonifer, Constanze 分享 收藏
RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction Ptasinska, Anetta; Pickin, Anna; Assi, Salam A.; Chin, Paulynn Suyin; Ames, Luke; Avellino, Roberto; Groeschel, Stephan; Delwel, Ruud; Cockerill, Peter N.; Osborne, Cameron S.; Bonifer, Constanze 分享 收藏
Subtype-specific regulatory network rewiring in acute myeloid leukemia Assi, Salam A.; Imperato, Maria Rosaria; Coleman, Daniel J. L.; Pickin, Anna; Potluri, Sandeep; Ptasinska, Anetta; Chin, Paulynn Suyin; Blair, Helen; Cauchy, Pierre; James, Sally R.; Zacarias-Cabeza, Joaquin; Gilding, L. Niall; Beggs, Andrew; Clokie, Sam; Loke, Justin C.; Jenkin, Phil; Uddin, Ash; Delwel, Ruud; Richards, Stephen J.; Raghavan, Manoj; Griffiths, Michael J.; Heidenreich, Olaf; Cockerill, Peter N.; Bonifer, Constanze 分享 收藏
EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors (vol 24, pg 705, 2017) Zjablovskaja, Polina; Kardosova, Miroslava; Danek, Petr; Angelisova, Pavla; Benoukraf, Touati; Wurm, Alexander A.; Kalina, Tomas; Sian, Stephanie; Balastik, Martin; Delwel, Ruud; Brdicka, Tomas; Tenen, Daniel G.; Behre, Gerhard; Fiore, Frederic; Malissen, Bernard; Horejsi, Vaclav; Alberich-Jorda, Meritxell 分享 收藏
The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia Numata, Akihiko; Kwok, Hui Si; Kawasaki, Akira; Li, Jia; Zhou, Qi-Ling; Kerry, Jon; Benoukraf, Touati; Bararia, Deepak; Li, Feng; Ballabio, Erica; Tapia, Marta; Deshpande, Aniruddha J.; Welner, Robert S.; Delwel, Ruud; Yang, Henry; Milne, Thomas A.; Taneja, Reshma; Tenen, Daniel G. 分享 收藏
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia (vol 3, 688, 2012) Li, Zejuan; Huang, Hao; Chen, Ping; He, Miao; Li, Yuanyuan; Arnovitz, Stephen; Jiang, Xi; He, Chunjiang; Hyjek, Elizabeth; Zhang, Jun; Zhang, Zhiyu; Elkahloun, Abdel; Cao, Donglin; Shen, Chen; Wunderlich, Mark; Wang, Yungui; Neilly, Mary Beth; Jin, Jie; Wei, Minjie; Lu, Jun; Valk, Peter J. M.; Delwel, Ruud; Lowenberg, Bob; Le Beau, Michelle M.; Vardiman, James; Mulloy, James C.; Zeleznik-Le, Nancy J.; Liu, Paul P.; Zhang, Jiwang; Chen, Jianjun 分享 收藏
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