James A. Gallagher - Publications, H-index & Citations

James A. Gallagher

University of Liverpool

39H指数

198论文数

4.0K被引数

收录论文 39

发表时间

Urinary metabolite model to predict the dying process in lung cancer patients

COMMUNICATIONS MEDICINE

IF6.3

2025-02-27

OAAI

Coyle, Seamus; Chapman, Elinor; Hughes, David M.; Baker, James; Slater, Rachael; Davison, Andrew S.; Norman, Brendan P.; Roberts, Ivayla; Nwosu, Amara C.; Gallagher, James A.; Ranganath, Lakshminarayan R.; Boyd, Mark T.; Mayland, Catriona R.; Kell, Douglas B.; Mason, Stephen; Ellershaw, John; Probert, Chris

Alkaptonuria

NATURE REVIEWS DISEASE PRIMERS

IF60.6

2024-03-07

PREAI

Bernardini, Giulia; Braconi, Daniela; Zatkova, Andrea; Sireau, Nick; Kujawa, Mariusz J.; Introne, Wendy J.; Spiga, Ottavia; Geminiani, Michela; Gallagher, James A.; Ranganath, Lakshminarayan R.; Santucci, Annalisa

Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial

CELLS

IF5.2

2023-06-21

OAAI

Ooi, Nicola; Cooper, Ian R.; Norman, Brendan; Gallagher, James A.; Sireau, Nick; Bou-Gharios, George; Ranganath, Lakshminarayan R.; Savage, Victoria J.

Effects of Nitisinone on Oxidative and Inflammatory Markers in Alkaptonuria: Results from SONIA1 and SONIA2 Studies

CELLS

IF5.2

2022-11-18

OAAI

Braconi, Daniela; Geminiani, Michela; Psarelli, Eftychia Eirini; Giustarini, Daniela; Marzocchi, Barbara; Rossi, Ranieri; Bernardini, Giulia; Spiga, Ottavia; Gallagher, James A.; Kim-Hanh Le Quan Sang; Arnoux, Jean-Baptiste; Imrich, Richard; Al-Sbou, Mohammed S.; Gornall, Matthew; Jackson, Richard; Ranganath, Lakshminarayan R.; Santucci, Annalisa

Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria

METABOLITES

IF3.7

2022-09-29

OAAI

Norman, Brendan P.; Davison, Andrew S.; Hickton, Bryony; Ross, Gordon A.; Milan, Anna M.; Hughes, Andrew T.; Wilson, Peter J. M.; Sutherland, Hazel; Hughes, Juliette H.; Roberts, Norman B.; Bou-Gharios, George; Gallagher, James A.; Ranganath, Lakshminarayan R.

Revisiting Quantification of Phenylalanine/Tyrosine Flux in the Ochronotic Pathway during Long-Term Nitisinone Treatment of Alkaptonuria

METABOLITES

IF3.7

2022-09-29

OAAI

Ranganath, Lakshminarayan R.; Hughes, Andrew T.; Davison, Andrew S.; Khedr, Milad; Imrich, Richard; Rudebeck, Mattias; Olsson, Birgitta; Norman, Brendan P.; Bou-Gharios, George; Gallagher, James A.; Milan, Anna M.

Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment

METABOLITES

IF3.7

2022-08-22

OAAI

Ranganath, Lakshminarayan R.; Milan, Anna M.; Hughes, Andrew T.; Davison, Andrew S.; Khedr, Milad; Imrich, Richard; Rudebeck, Mattias; Olsson, Birgitta; Norman, Brendan P.; Bou-Gharios, George; Gallagher, James A.

Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism

GENES & DISEASES

IF9.4

2022-07-01

OAAI

Norman, Brendan P.; Davison, Andrew S.; Hughes, Juliette H.; Sutherland, Hazel; Wilson, Peter JM.; Berry, Neil G.; Hughes, Andrew T.; Milan, Anna M.; Jarvis, Jonathan C.; Roberts, Norman B.; Ranganath, Lakshminarayan R.; Bou-Gharios, George; Gallagher, James A.

Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria

METABOLITES

IF3.7

2022-05-25

OAAI

Davison, Andrew S.; Norman, Brendan P.; Sutherland, Hazel; Milan, Anna M.; Gallagher, James A.; Jarvis, Jonathan C.; Ranganath, Lakshminarayan R.

Lessons from Rare Forms of Osteoarthritis

CALCIFIED TISSUE INTERNATIONAL

IF3.2

2021-08-21

OAAI

Shepherd, Rebecca F.; Kerns, Jemma G.; Ranganath, Lakshminarayan R.; Gallagher, James A.; Taylor, Adam M.

Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces

CALCIFIED TISSUE INTERNATIONAL

IF3.2

2020-10-14

OAAI

Hughes, Juliette H.; Keenan, Craig M.; Sutherland, Hazel; Edwards, Henry R.; Wilson, Peter J. M.; Ranganath, Lakshminarayan R.; Jarvis, Jonathan C.; Bou-Gharios, George; Gallagher, James A.

Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2020-05-14

OAAI

Chow, Wing Ying; Norman, Brendan P.; Roberts, Norman B.; Ranganath, Lakshminarayan R.; Teutloff, Christian; Bittl, Robert; Duer, Melinda J.; Gallagher, James A.; Oschkinat, Hartmut

Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria

HUMAN MOLECULAR GENETICS

IF3.2

2019-10-10

OAAI

Hughes, Juliette H.; Liu, Ke; Plagge, Antonius; Wilson, Peter J. M.; Sutherland, Hazel; Norman, Brendan P.; Hughes, Andrew T.; Keenan, Craig M.; Milan, Anna M.; Sakai, Takao; Ranganath, Lakshminarayan R.; Gallagher, James A.; Bou-Gharios, George

Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice

SCIENTIFIC REPORTS

IF3.9

2019-08-01

OAAI

Keenan, Craig M.; Beckett, Alison J.; Sutherland, Hazel; Ranganath, Lakshminarayan R.; Jarvis, Jonathan C.; Prior, Ian A.; Gallagher, James A.

A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria

CLINICAL CHEMISTRY

IF6.3

2019-04-01

OAAI

Norman, Brendan P.; Davison, Andrew S.; Ross, Gordon A.; Milan, Anna M.; Hughes, Andrew T.; Sutherland, Hazel; Jarvis, Jonathan C.; Roberts, Norman B.; Gallagher, James A.; Ranganath, Lakshminarayan R.

Defining the Properties of an Array of -NH2-Modified Substrates for the Induction of a Mature Osteoblast/Osteocyte Phenotype from a Primary Human Osteoblast Population Using Controlled Nanotopography and Surface Chemistry

CALCIFIED TISSUE INTERNATIONAL

IF3.2

2016-10-28

OAAI

Fawcett, Sandra A.; Curran, Judith M.; Chen, Rui; Rhodes, Nicholas P.; Murphy, Mark F.; Wilson, Peter; Ranganath, Lakshminarayan; Dillon, Jane P.; Gallagher, James A.; Hunt, John A.

c-Fos induction by gut hormones and extracellular ATP in osteoblastic-like cell lines

Purinergic Signalling

IF2.4

2016-07-20

OAAI

Pacheco-Pantoja, Elda Leonor; Dillon, Jane P.; Wilson, Peter J. M.; Fraser, William D.; Gallagher, James A.

Alkaptonuria: An example of a fundamental disease-A rare disease with important lessons for more common disorders

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2016-04-01

PREAI

Gallagher, James A.; Dillon, Jane P.; Sireau, Nicolas; Timmis, Oliver; Ranganath, Lakshminarayan R.

Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2016-02-01

105

OAAI

Ranganath, Lakshminarayan R.; Milan, Anna M.; Hughes, Andrew T.; Dutton, John J.; Fitzgerald, Richard; Briggs, Michael C.; Bygott, Helen; Psarelli, Eftychia E.; Cox, Trevor F.; Gallagher, James A.; Jarvis, Jonathan C.; van Kan, Christa; Hall, Anthony K.; Laan, Dinny; Olsson, Birgitta; Szamosi, Johan; Rudebeck, Mattias; Kullenberg, Torbjorn; Cronlund, Arvid; Svensson, Lennart; Junestrand, Carin; Ayoob, Hana; Timmis, Oliver G.; Sireau, Nicolas; Le Quan Sang, Kim-Hanh; Genovese, Federica; Braconi, Daniela; Santucci, Annalisa; Nemethova, Martina; Zatkova, Andrea; McCaffrey, Judith; Christensen, Peter; Ross, Gordon; Imrich, Richard; Rovensky, Jozef

Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury

PURINERGIC SIGNALLING

IF2.4

2016-01-29

OAAI

Varley, Ian; Greeves, Julie P.; Sale, Craig; Friedman, Eitan; Moran, Daniel S.; Yanovich, Ran; Wilson, Peter J.; Gartland, Alison; Hughes, David C.; Stellingwerff, Trent; Ranson, Craig; Fraser, William D.; Gallagher, James A.

研究方向