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Structural and mechanistic insights into the sequential dsDNA cleavage by SpCas12f1 SpCas12f1对dsDNA的顺序切割的结构与机制洞察 Madariaga-Marcos, Julene; Baltramonaitis, Marius; Henkel-Heinecke, Selgar; Kauert, Dominik J.; Irmisch, Patrick; Bigelyte-Stankeviciene, Greta; Silanskas, Arunas; Karvelis, Tautvydas; Siksnys, Virginijus; Sasnauskas, Giedrius; Seidel, Ralf 分享 收藏
Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing Bigelyte, Greta; Duchovska, Brigita; Zedaveinyte, Rimante; Sasnauskas, Giedrius; Sinkunas, Tomas; Dalgediene, Indre; Tamulaitiene, Giedre; Silanskas, Arunas; Kazlauskas, Darius; Valancauskas, Lukas; Madariaga-Marcos, Julene; Seidel, Ralf; Siksnys, Virginijus; Karvelis, Tautvydas 分享 收藏
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Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors Schmitz, Claus; Madej, Mariusz; Nowakowska, Zuzanna; Cuppari, Anna; Jacula, Anna; Ksiazek, Miroslaw; Mikruta, Katarzyna; Wisniewski, Jerzy; Pudelko-Malik, Natalia; Saran, Anshu; Zeytuni, Natalie; Mlynarz, Piotr; Lamont, Richard J.; Uson, Isabel; Siksnys, Virginijus; Potempa, Jan; Sola, Maria 分享 收藏
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A new family of CRISPR-type V nucleases with C-rich PAM recognition Urbaitis, Tomas; Gasiunas, Giedrius; Young, Joshua K.; Hou, Zhenglin; Paulraj, Sushmitha; Godliauskaite, Egle; Juskeviciene, Mantvyda M.; Stitilyte, Migle; Jasnauskaite, Monika; Mabuchi, Megumu; Robb, G. Brett; Siksnys, Virginijus 分享 收藏
Miniature type V-F CRISPR-Cas nucleases enable targeted DNA modification in cells Bigelyte, Greta; Young, Joshua K.; Karvelis, Tautvydas; Budre, Karolina; Zedaveinyte, Rimante; Djukanovic, Vesna; Van Ginkel, Elizabeth; Paulraj, Sushmitha; Gasior, Stephen; Jones, Spencer; Feigenbutz, Lanie; St Clair, Grace; Barone, Pierluigi; Bohn, Jennifer; Acharya, Ananta; Zastrow-Hayes, Gina; Henkel-Heinecke, Selgar; Silanskas, Arunas; Seidel, Ralf; Siksnys, Virginijus 分享 收藏
Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor Balderston, Sarah; Taulbee, Jeffrey J.; Celaya, Elizabeth; Fung, Kandace; Jiao, Amanda; Smith, Kasey; Hajian, Reza; Gasiunas, Giedrius; Kutanovas, Simonas; Kim, Daehwan; Parkinson, Jonathan; Dickerson, Kenneth; Ripoll, Juan-Jose; Peytavi, Regis; Lu, Hsiang-Wei; Barron, Francie; Goldsmith, Brett R.; Collins, Philip G.; Conboy, Irina M.; Siksnys, Virginijus; Aran, Kiana 分享 收藏
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A catalogue of biochemically diverse CRISPR-Cas9 orthologs 生物化学上多样化的CRISPR-Cas9直系同源物目录 Gasiunas, Giedrius; Young, Joshua K.; Karvelis, Tautvydas; Kazlauskas, Darius; Urbaitis, Tomas; Jasnauskaite, Monika; Grusyte, Mantvyda M.; Paulraj, Sushmitha; Wang, Po-Hao; Hou, Zhenglin; Dooley, Shane K.; Cigan, Mark; Alarcon, Clara; Chilcoat, N. Doane; Bigelyte, Greta; Curcuru, Jennifer L.; Mabuchi, Megumu; Sun, Zhiyi; Fuchs, Ryan T.; Schildkraut, Ezra; Weigele, Peter R.; Jack, William E.; Robb, G. Brett; Venclovas, Ceslovas; Siksnys, Virginijus 分享 收藏
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Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish Fricke, Thomas; Smalakyte, Dalia; Lapinski, Maciej; Pateria, Abhishek; Weige, Charles; Pastor, Michal; Kolano, Agnieszka; Winata, Cecilia; Siksnys, Virginijus; Tamulaitis, Gintautas; Bochtler, Matthias 分享 收藏
Evolutionary and functional classification of the CARF domain superfamily, key sensors in prokaryotic antivirus defense CARF结构域超家族的进化和功能分类，原核抗病毒防御中的关键传感器 Makarova, Kira S.; Timinskas, Albertas; Wolf, Yuri, I; Gussow, Ayal B.; Siksnys, Virginijus; Venclovas, Ceslovas; Koonin, Eugene, V 分享 收藏
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PAM recognition by miniature CRISPR-Cas12f nucleases triggers programmable double-stranded DNA target cleavage 微型CRISPR-Cas12f核酸酶对PAM的识别触发了可编程的双链DNA靶标切割 Karvelis, Tautvydas; Bigelyte, Greta; Young, Joshua K.; Hou, Zhenglin; Zedaveinyte, Rimante; Budre, Karolina; Paulraj, Sushmitha; Djukanovic, Vesna; Gasior, Stephen; Silanskas, Arunas; Venclovas, Ceslovas; Siksnys, Virginijus 分享 收藏
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