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Targeting Aggressive B-cell Lymphomas through Pharmacological Activation of the Mitochondrial Protease OMA1 通过线粒体蛋白酶OMA1的药理激活靶向侵袭性b细胞淋巴瘤 Schwarzer, Adrian; Oliveira, Matheus; Kleppa, Marc-Jens; Slattery, Scott D.; Anantha, Andy; Cooper, Alan; Hannink, Mark; Schambach, Axel; Dorrie, Anneke; Kotlyarov, Alexey; Gaestel, Matthias; Hembrough, Todd; Levine, Jedd; Luther, Michael; Stocum, Michael; Stiles, Linsey; Weinstock, David M.; Liesa, Marc; Kostura, Matthew J. 分享 收藏
Pharmacokinetics and pharmacodynamics of the novel OMA1 activator BTM 3566 in a mouse model of diffuse large B-cell lymphoma Bagherzadeh, Azadeh; Baker, Jennifer; Bennett, Charlotte; Lee, Mi-Young; Pacheco, Natalia; Patel, Bhavisha; Stewart, Kevin; Travers, Jon; Stocum, Michael; Hembrough, Todd; Kostura, Matthew 分享 收藏
MET Exon 14-altered Lung Cancers and MET Inhibitor Resistance MET外显子14改变的肺癌和MET抑制剂耐药 Guo, Robin; Offin, Michael; Brannon, A. Rose; Chang, Jason; Chow, Andrew; Delasos, Lukas; Girshman, Jeffrey; Wilkins, Olivia; McCarthy, Caroline G.; Makhnin, Alex; Falcon, Christina; Scott, Kerry; Tian, Yuan; Cecchi, Fabiola; Hembrough, Todd; Alex, Deepu; Shen, Ronglai; Benayed, Ryma; Li, Bob T.; Rudin, Charles M.; Kris, Mark G.; Arcila, Maria E.; Rekhtman, Natasha; Paik, Paul; Zehir, Ahmet; Drilon, Alexander 分享 收藏
Prognostic and Predictive Impact of Circulating Tumor DNA in Patients with Advanced Cancers Treated with Immune Checkpoint Blockade Zhang, Qu; Luo, Jia; Wu, Song; Si, Han; Gao, Chen; Xu, Wenjing; Abdullah, Shaad E.; Higgs, Brandon W.; Dennis, Phillip A.; van der Heijden, Michiel S.; Segal, Neil H.; Chaft, Jamie E.; Hembrough, Todd; Barrett, J. Carl; Hellmann, Matthew D. 分享 收藏
High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies Toulmonde, Maud; Lucchesi, Carlo; Verbeke, Stephanie; Crombe, Amandine; Adam, Julien; Geneste, Damien; Chaire, Vanessa; Laroche-Clary, Audrey; Perret, Raul; Bertucci, Francois; Bertolo, Frederic; Bianchini, Laurence; Dadone-Montaudie, Berengere; Hembrough, Todd; Sweet, Steve; Kim, Yeoun Jin; Cecchi, Fabiola; Le Loarer, Francois; Italiano, Antoine 分享 收藏
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HER2 low testing in breast cancer: How to optimize detection Cecchi, F.; Carrolle, D.; Gustavson, M.; Sridhar, S.; de los Reyes, M.; Thyparambil, S.; Bhalkikar, A.; Liao, W-L.; Coats, S.; Hembrough, T. 分享 收藏
Overcoming hypoxia-induced functional suppression of NK cells 克服缺氧诱导的NK细胞功能抑制 Solocinski, Kristen; Padget, Michelle R.; Fabian, Kellsye P.; Wolfson, Benjamin; Cecchi, Fabiola; Hembrough, Todd; Benz, Stephen C.; Rabizadeh, Shahrooz; Soon-Shiong, Patrick; Schlom, Jeffrey; Hodge, James W. 分享 收藏
Characterization of MGMT and EGFR protein expression in glioblastoma and association with survival Schaff, Lauren R.; Yan, Dongyao; Thyparambil, Sheeno; Tian, Yuan; Cecchi, Fabiola; Rosenblum, Marc; Reiner, Anne S.; Panageas, Katherine S.; Hembrough, Todd; Lin, Andrew L. 分享 收藏
Targeted multiplex proteomics for molecular prescreening and biomarker discovery in metastatic colorectal cancer 靶向多重蛋白质组学用于转移性结直肠癌的分子预筛选和生物标志物发现 Serna, Garazi; Ruiz-Pace, Fiorella; Cecchi, Fabiola; Fasani, Roberta; Jimenez, Jose; Thyparambil, Sheen; Landolfi, Stefania; Elez, Elena; Vivancos, Ana; Hembrough, Todd; Tabernero, Josep; Dienstmann, Rodrigo; Nuciforo, Paolo 分享 收藏
EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer EGFR和MET扩增决定了ERBB2-Amplified食管胃癌对HER2抑制的反应 Sanchez-Vega, Francisco; Hechtman, Jaclyn F.; Castel, Pau; Ku, Geoffrey Y.; Tuvy, Yaelle; Won, Helen; Fong, Christopher J.; Bouvier, Nancy; Nanjangud, Gouri J.; Soong, Joanne; Vakiani, Efsevia; Schattner, Mark; Kelsen, David P.; Lefkowitz, Robert A.; Brown, Karen; Lacouture, Mario E.; Capanu, Marinela; Mattar, Marissa; Qeriqi, Besnik; Cecchi, Fabiola; Tian, Yuan; Hembrough, Todd; Nagy, Rebecca J.; Lanman, Richard B.; Larson, Steven M.; Pandit-Taskar, Neeta; Schoder, Heiko; Iacobuzio-Donahue, Christine A.; Ilson, David H.; Weber, Wolfgang A.; Berger, Michael F.; De Stanchina, Elisa; Taylor, Barry S.; Lewis, Jason S.; Solit, David B.; Carrasquillo, Jorge A.; Scaltriti, Maurizio; Schultz, Nikolaus; Janjigian, Yelena Y. 分享 收藏
Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase Schwartz, Sarit; Szeto, Chris; Tian, Yuan; Cecchi, Fabiola; Corallo, Salvatore; Calegari, Maria Alessandra; Di Bartolomeo, Maria; Morano, Federica; Raimondi, Alessandra; Fuca, Giovanni; Martinetti, Antonia; De Pascalis, Ivana; Martini, Maurizio; Belfiore, Antonino; Milione, Massimo; Orlandi, Armando; Barault, Ludovic; Barone, Carlo; de Braud, Filippo; Di Nicolantonio, Federica; Benz, Steve; Hembrough, Todd; Pietrantonio, Filippo 分享 收藏
Data-Independent Acquisition Mass Spectrometry To Quantify Protein Levels in FFPE Tumor Biopsies for Molecular Diagnostics Kim, Yeoun Jin; Sweet, Steve M. M.; Egertson, Jarrett D.; Sedgewick, Andrew J.; Woo, Sunghee; Liao, Wei-li; Merrihew, Gennifer E.; Searle, Brian C.; Vaske, Charlie; Heaton, Robert; MacCoss, Michael J.; Hembrough, Todd 分享 收藏
Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition (vol 24, pg 968, 2018) Wong, Gabrielle S.; Zhou, Jin; Liu, Jie Bin; Wu, Zhong; Xu, Xinsen; Li, Tianxia; Xu, David; Schumacher, Steven E.; Puschhof, Jens; McFarland, James; Zou, Charles; Dulak, Austin; Henderson, Les; Xu, Peng; O'Day, Emily; Rendak, Rachel; Liao, Wei-li; Cecchi, Fabiola; Hembrough, Todd; Schwartz, Sarit; Szeto, Christopher; Rustgi, Anil K.; Wong, Kwok-Kin; Diehl, J. Alan; Jensen, Karin; Graziano, Francesco; Ruzzo, Annamaria; Fereshetian, Shaunt; Mertins, Philipp; Carr, Steven A.; Beroukhim, Rameen; Nakamura, Kenichi; Oki, Eiji; Watanabe, Masayuki; Baba, Hideo; Imamura, Yu; Catenacci, Daniel; Bass, Adam J. 分享 收藏
Potential drug targets for adenoid cystic carcinoma elucidated by proteogenomic analysis Thyparambil, Sheeno P.; Kim, Yeoun Jin; Chambers, Andrew G.; Yan, Dongyao; Sellappan, Shankar; Sedgewick, Andrew J.; Newton, Yulia; Sanborn, J. Zachary; Vaske, Charles J.; Benz, Stephen C.; Cecchi, Fabiola; Kang, Hyunseok; Hembrough, Todd A. 分享 收藏
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Targeted Therapies for Targeted Populations: Anti-EGFR Treatment for EGFR-Amplified Gastroesophageal Adenocarcinoma Maron, Steven B.; Alpert, Lindsay; Kwak, Heewon A.; Lomnicki, Samantha; Chase, Leah; Xu, David; O'Day, Emily; Nagy, Rebecca J.; Lanman, Richard B.; Cecchi, Fabiola; Hembrough, Todd; Schrock, Alexa; Hart, John; Xiao, Shu-Yuan; Setia, Namrata; Catenacci, Daniel V. T. 分享 收藏
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