George K. Aghajanian - Publications, H-index & Citations

George K. Aghajanian

Yale University

113H指数

293论文数

4.6W被引数

收录论文 25

发表时间

Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities

BIOLOGICAL PSYCHIATRY

IF9

2021-07-01

PREAI

Shinohara, Ryota; Aghajanian, George K.; Abdallah, Chadi G.

Torgny Svensson, MD, Ph.D. (1945-2020) IN MEMORIAM

NEUROPSYCHOPHARMACOLOGY

IF7.1

2020-07-22

OAAI

Aghajanian, George K.; Mathe, Aleksander A.; Eriksson, Elias; Krystal, John H.

GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine

NEUROPSYCHOPHARMACOLOGY

IF7.1

2016-09-16

OAAI

Liu, Rong-Jian; Duman, Catharine; Kato, Taro; Hare, Brendan; Lopresto, Dora; Bang, Eunyoung; Burgdorf, Jeffery; Moskal, Joseph; Taylor, Jane; Aghajanian, George; Duman, Ronald S.

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants 突触可塑性和抑郁: 来自压力和速效抗抑郁药的新见解

NATURE MEDICINE

IF50

2016-03-03

1.2K

OAAI

Duman, Ronald S.; Aghajanian, George K.; Sanacora, Gerard; Krysta, John H.

Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-06-08

227

OAAI

Fuchikami, Manabu; Thomas, Alexandra; Liu, Rongjian; Wohleb, Eric S.; Land, Benjamin B.; DiLeone, Ralph J.; Aghajanian, George K.; Duman, Ronald S.

Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses

NEUROPSYCHOPHARMACOLOGY

IF7.1

2015-03-11

OAAI

Liu, Rong-Jian; Ota, Kristie T.; Dutheil, Sophie; Duman, Ronald S.; Aghajanian, George K.

REDD1 is essential for stress-induced synaptic loss and depressive behavior

NATURE MEDICINE

IF50

2014-04-13

226

OAAI

Ota, Kristie T.; Liu, Rong-Jian; Voleti, Bhavya; Maldonado-Aviles, Jaime G.; Duric, Vanja; Iwata, Masaaki; Dutheil, Sophie; Duman, Catharine; Boikess, Steve; Lewis, David A.; Stockmeier, Craig A.; DiLeone, Ralph J.; Rex, Christopher; Aghajanian, George K.; Duman, Ronald S.

Neurobiology of Rapid Acting Antidepressants: Role of BDNF and GSK-3β

NEUROPSYCHOPHARMACOLOGY

IF7.1

2013-12-09

OAAI

Duman, Ronald S.; Aghajanian, George K.

Scopolamine Rapidly Increases Mammalian Target of Rapamycin Complex 1 Signaling, Synaptogenesis, and Antidepressant Behavioral Responses

BIOLOGICAL PSYCHIATRY

IF9

2013-11-01

229

OAAI

Voleti, Bhavya; Navarria, Andrea; Liu, Rong-Jian; Banasr, Mounira; Li, Nanxin; Terwilliger, Rose; Sanacora, Gerard; Eid, Tore; Aghajanian, George; Duman, Ronald S.

GSK-3 Inhibition Potentiates the Synaptogenic and Antidepressant-Like Effects of Subthreshold Doses of Ketamine

NEUROPSYCHOPHARMACOLOGY

IF7.1

2013-05-17

220

OAAI

Liu, Rong-Jian; Fuchikami, Manabu; Dwyer, Jason M.; Lepack, Ashley E.; Duman, Ronald S.; Aghajanian, George K.

Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex

BIOLOGICAL PSYCHIATRY

IF9

2012-06-01

336

OAAI

Liu, Rong-Jian; Lee, Francis S.; Li, Xiao-Yuan; Bambico, Francis; Duman, Ronald S.; Aghajanian, George K.

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure 谷氨酸N-甲基-D-天冬氨酸受体拮抗剂可快速逆转慢性应激暴露引起的行为和突触缺陷

BIOLOGICAL PSYCHIATRY

IF9

2011-04-01

970

OAAI

Li, Nanxin; Liu, Rong-Jian; Dwyer, Jason M.; Banasr, Mounira; Lee, Boyoung; Son, Hyeon; Li, Xiao-Yuan; Aghajanian, George; Duman, Ronald S.

Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: Behavioral, electrophysiological, and molecular studies

BIOLOGICAL PSYCHIATRY

IF9

2008-06-01

OAAI

Zachariou, Venetia; Liu, Rongjian; LaPlant, Quincey; Xiao, Guanghua; Renthal, William; Chan, Guy C.; Storm, Daniel R.; Aghajanian, George; Nestler, Eric J.

Schizophrenia, hypocretin (Orexin), and the thalamocortical activating system

SCHIZOPHRENIA BULLETIN

IF4.8

2006-10-27

OAAI

Lambe, Evelyn K.; Liu, Rong-Jian; Aghajanian, George K.

Hallucinogen-induced UP states in the brain slice of rat-prefrontal cortex: Role of glutamate spillover and NR2B-NMDA receptors

NEUROPSYCHOPHARMACOLOGY

IF7.1

2005-11-02

OAAI

Lambe, Evelyn K.; Aghajanian, George K.

Hypocretin (orexin) induces calcium transients in single spines postsynaptic to identified thalamocortical boutons in prefrontal slice

NEURON

IF15

2003-09-01

108

OAAI

Lambe, EK; Aghajanian, GK

Nicotine induces glutamate release from thalamocortical terminals in prefrontal cortex

NEUROPSYCHOPHARMACOLOGY

IF7.1

2003-02-14

243

OAAI

Lambe, EK; Picciotto, MR; Aghajanian, GK

Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal

MOLECULAR PSYCHIATRY

IF10.1

2001-08-29

PREAI

Akbarian, S; Bates, B; Liu, RJ; Skirboll, SL; Pejchal, T; Coppola, V; Sun, LD; Fan, G; Kucera, J; Wilson, MA; Tessarollo, L; Kosofsky, BE; Taylor, JR; Bothwell, M; Nestler, EJ; Aghajanian, GK; Jaenisch, R

Molecular control of locus coeruleus neurotransmission

BIOLOGICAL PSYCHIATRY

IF9

1999-11-01

139

PREAI

Nestler, EJ; Alreja, M; Aghajanian, GK

5-HT2A receptor or α1-adrenoceptor activation induces excitatory postsynaptic currents in layer V pyramidal cells of the medial prefrontal cortex

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

1999-02-01

209

OAAI

Marek, GJ; Aghajanian, GK

研究方向