未登录

J

John C. Shryock

State University System of Florida

H指数:44

被引数:6,573

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Cardiac late Na+ current: Proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress

IF5.7

2015-02-01107

PREAI

Intracellular Na+ overload causes oxidation of CaMKII and leads to Ca2+ mishandling in isolated ventricular myocytes

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2014-11-0150

OAAI

The arrhythmogenic consequences of increasing late INa in the cardiomyocyte

CARDIOVASCULAR RESEARCH

IF13.3

2013-06-10114

OAAI

Intracellular Na+ Overload of Cardiomyocytes Causes ROS Induced CaMKII Activation, Leading to RYR Dysfunction and Diastolic Ca2+ Mishandling

BIOPHYSICAL JOURNAL

IF3.1

2013-01-010

OAAI

A Novel, Potent, and Selective Inhibitor of Cardiac Late Sodium Current Suppresses Experimental Arrhythmias

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2013-01-01190

PREAI

Inhibition of Apoptosis Signal-Regulating Kinase 1 Reduces Myocardial Ischemia-Reperfusion Injury in the Mouse

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2012-09-2643

OAAI

Calmodulin kinase II and protein kinase C mediate the effect of increased intracellular calcium to augment late sodium current in rabbit ventricular myocytes

钙调蛋白激酶II和蛋白激酶C介导细胞内钙增加对兔心室肌细胞晚期钠电流的影响

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2012-04-1548

PREAI

Ambrisentan and Tadalafil Synergistically Relax Endothelin-Induced Contraction of Rat Pulmonary Arteries

IF8.2

2012-03-0127

OAAI

Selective action of metoprolol to attenuate regadenoson-induced tachycardia in conscious dogs

美托洛尔对减轻清醒犬regadenoson引起的心动过速的选择性作用

JOURNAL OF NUCLEAR CARDIOLOGY

IF2.7

2012-02-012

PREAI

Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A1 adenosine receptor

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2012-01-0112

PRE

Ros and CaMKII Modulate Sodium Overload-Induced Calcium Leak from Ryanodine Receptors in Ventricular Myocytes

BIOPHYSICAL JOURNAL

IF3.1

2012-01-010

OAAI

Contribution of Local Anesthetic Binding Site Residues F1760 and Y1767 to Block of the Cardiac Na+ Channel, hNaV1.5, by Ranolazine

BIOPHYSICAL JOURNAL

IF3.1

2012-01-011

OAAI

Ranolazine Reduces Central Neuron Excitability by Slowly Interacting with NaV Channels

BIOPHYSICAL JOURNAL

IF3.1

2012-01-010

OAAI

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2011-09-0189

PREAI

Late Sodium Current Contributes to the Reverse Rate-Dependent Effect of IKr Inhibition on Ventricular Repolarization

IF38.6

2011-04-26105

OAAI

LQTS mutation N1325S in cardiac sodium channel gene SCN5A causes cardiomyocyte apoptosis, cardiac fibrosis and contractile dysfunction in mice

INTERNATIONAL JOURNAL OF CARDIOLOGY

IF3.2

2011-03-0130

OAAI

Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis (vol 16, pg 1024, 2010)

NATURE MEDICINE

IF50

2011-02-040

OAAI

Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis

NATURE MEDICINE

IF50

2010-08-2298

OAAI

Sulfonylureas uncouple glucose-dependence for GPR40-mediated enhancement of insulin secretion from INS-1E cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2010-02-0116

PREAI

Use-Dependent Block of Nav1.4 Human Paramyotonia Congenita Mutation By Ranolazine

BIOPHYSICAL JOURNAL

IF3.1

2010-01-010

OAAI