未登录 RECOVER identifies synergistic drug combinations in vitro through sequential model optimization Bertin, Paul; Rector-Brooks, Jarrid; Sharma, Deepak; Gaudelet, Thomas; Anighoro, Andrew; Gross, Torsten; Martinez-Pena, Francisco; Tang, Eileen L.; Suraj, M. S.; Regep, Cristian; Hayter, Jeremy B. R.; Korablyov, Maksym; Valiante, Nicholas; van der Sloot, Almer; Tyers, Mike; Roberts, Charles E. S.; Bronstein, Michael M.; Lairson, Luke L.; Taylor-King, Jake P.; Bengio, Yoshua 分享 收藏
A Novel Toll-Like Receptor 2 Agonist Protects Mice in a Prophylactic Treatment Model Against Challenge With Bacillus anthracis Chiang, Chih-Yuan; Lane, Douglas J.; Zou, Yefen; Hoffman, Tim; Pan, Jianfeng; Hampton, Janice; Maginnis, Jillian; Nayak, Bishnu P.; D'Oro, Ugo; Valiante, Nicholas; Miller, Andrew T.; Cooke, Michael; Wu, Tom; Bavari, Sina; Panchal, Rekha G. 分享 收藏
Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs Francica, Joseph R.; Zak, Daniel E.; Linde, Caitlyn; Siena, Emilio; Johnson, Carrie; Juraska, Michal; Yates, Nicole L.; Gunn, Bronwyn; De Gregorio, Ennio; Flynn, Barbara J.; Valiante, Nicholas M.; Malyala, Padma; Barnett, Susan W.; Sarkar, Pampi; Singh, Manmohan; Jain, Siddhartha; Ackerman, Margaret; Alam, Munir; Ferrari, Guido; Tomaras, Georgia D.; O'Hagan, Derek T.; Aderem, Alan; Alter, Galit; Seder, Robert A. 分享 收藏
Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines Buonsanti, Cecilia; Balocchi, Cristiana; Harfouche, Carole; Corrente, Federica; Stampino, Luisa Galli; Mancini, Francesca; Tontini, Marta; Malyala, Padma; Bufali, Simone; Baudner, Barbara; De Gregorio, Ennio; Valiante, Nicholas M.; O'Hagan, Derek T.; Rappuoli, Rino; D'Oro, Ugo 分享 收藏
Incorporation of Phosphonate into Benzonaphthyridine Toll-like Receptor 7 Agonists for Adsorption to Aluminum Hydroxide Cortez, Alex; Li, Yongkai; Miller, Andrew T.; Zhang, Xiaoyue; Yue, Kathy; Maginnis, Jillian; Hampton, Janice; Hall, De Shon; Shapiro, Michael; Nayak, Bishnu; D'Oro, Ugo; Li, Chun; Skibinski, David; Mbow, M. Lamine; Singh, Manmohan; O'Hagan, Derek T.; Cooke, Michael P.; Valiante, Nicholas M.; Wu, Tom Y. -H. 分享 收藏
A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells 一种新的TLR2激动剂促进小鼠和人抗原呈递细胞的交叉呈递 Santone, Melissa; Aprea, Susanna; Wu, Tom Y. H.; Cooke, Michael P.; Mbow, M. Lamine; Valiante, Nicholas M.; Rush, James S.; Dougan, Stephanie; Avalos, Ana; Ploegh, Hidde; De Gregorio, Ennio; Buonsanti, Cecilia; D'Oro, Ugo 分享 收藏
Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization Francica, Joseph R.; Sheng, Zizhang; Zhang, Zhenhai; Nishimura, Yoshiaki; Shingai, Masashi; Ramesh, Akshaya; Keele, Brandon F.; Schmidt, Stephen D.; Flynn, Barbara J.; Darko, Sam; Lynch, Rebecca M.; Yamamoto, Takuya; Matus-Nicodemos, Rodrigo; Wolinsky, David; Nason, Martha; Valiante, Nicholas M.; Malyala, Padma; De Gregorio, Ennio; Barnett, Susan W.; Singh, Manmohan; O'Hagan, Derek T.; Koup, Richard A.; Mascola, John R.; Martin, Malcolm A.; Kepler, Thomas B.; Douek, Daniel C.; Shapiro, Lawrence; Seder, Robert A. 分享 收藏
Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus Bagnoli, Fabio; Fontana, Maria Rita; Soldaini, Elisabetta; Mishra, Ravi P. N.; Fiaschi, Luigi; Cartocci, Elena; Nardi-Dei, Vincenzo; Ruggiero, Paolo; Nosari, Sarah; De Falco, Maria Grazia; Lofano, Giuseppe; Marchi, Sara; Galletti, Bruno; Mariotti, Paolo; Bacconi, Marta; Torre, Antonina; Maccari, Silvia; Scarselli, Maria; Rinaudo, C. Daniela; Inoshima, Naoko; Savino, Silvana; Mori, Elena; Rossi-Paccani, Silvia; Baudner, Barbara; Pallaoro, Michele; Swennen, Erwin; Petracca, Roberto; Brettoni, Cecilia; Liberatori, Sabrina; Norais, Nathalie; Monaci, Elisabetta; Wardenburg, Juliane Bubeck; Schneewind, Olaf; O'Hagan, Derek T.; Valiante, Nicholas M.; Bensi, Giuliano; Bertholet, Sylvie; De Gregorio, Ennio; Rappuoli, Rino; Grandi, Guido 分享 收藏
mTOR inhibition improves immune function in the elderly mTOR抑制改善老年人的免疫功能 Mannick, Joan B.; Del Giudice, Giuseppe; Lattanzi, Maria; Valiante, Nicholas M.; Praestgaard, Jens; Huang, Baisong; Lonetto, Michael A.; Maecker, Holden T.; Kovarik, John; Carson, Simon; Glass, David J.; Klickstein, Lloyd B. 分享 收藏
A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines Brito, Luis A.; Chan, Michelle; Shaw, Christine A.; Hekele, Armin; Carsillo, Thomas; Schaefer, Mary; Archer, Jacob; Seubert, Anja; Otten, Gillis R.; Beard, Clayton W.; Dey, Antu K.; Lilja, Anders; Valiante, Nicholas M.; Mason, Peter W.; Mandl, Christian W.; Barnett, Susan W.; Dormitzer, Philip R.; Ulmer, Jeffrey B.; Singh, Manmohan; O'Hagan, Derek T.; Geall, Andrew J. 分享 收藏
Rational design of small molecules as vaccine adjuvants Wu, Tom Y. -H.; Singh, Manmohan; Miller, Andrew T.; De Gregorio, Ennio; Doro, Francesco; D'Oro, Ugo; Skibinski, David A. G.; Mbow, M. Lamine; Bufali, Simone; Herman, Ann E.; Cortez, Alex; Li, Yongkai; Nayak, Bishnu P.; Tritto, Elaine; Filippi, Christophe M.; Otten, Gillis R.; Brito, Luis A.; Monaci, Elisabetta; Li, Chun; Aprea, Susanna; Valentini, Sara; Calabro, Samuele; Laera, Donatello; Brunelli, Brunella; Caproni, Elena; Malyala, Padma; Panchal, Rekha G.; Warren, Travis K.; Bavari, Sina; O'Hagan, Derek T.; Cooke, Michael P.; Valiante, Nicholas M. 分享 收藏
Nonviral delivery of self-amplifying RNA vaccines 自我扩增RNA疫苗的非病毒递送 Geall, Andrew J.; Verma, Ayush; Otten, Gillis R.; Shaw, Christine A.; Hekele, Armin; Banerjee, Kaustuv; Cu, Yen; Beard, Clayton W.; Brito, Luis A.; Krucker, Thomas; O'Hagan, Derek T.; Singh, Manmohan; Mason, Peter W.; Valiante, Nicholas M.; Dormitzer, Philip R.; Barnett, Susan W.; Rappuoli, Rino; Ulmer, Jeffrey B.; Mandl, Christian W. 分享 收藏
A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding Iavarone, Carlo; Ramsauer, Katrin; Kubarenko, Andriy V.; Debasitis, Jason C.; Leykin, Igor; Weber, Alexander N. R.; Siggs, Owen M.; Beutler, Bruce; Zhang, Pu; Otten, Gillis; D'Oro, Ugo; Valiante, Nicholas M.; Mbow, M. Lamine; Visintin, Alberto 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
未登录.png){kind=icon}