David L. Huso - Publications, H-index & Citations

David L. Huso

Johns Hopkins University

73H指数

357论文数

2.2W被引数

收录论文 97

发表时间

Differential Requirement for H2AX and 53BP1 in Organismal Development and Genome Maintenance in the Absence of Poly(ADP)ribosyl Polymerase 1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Orsburn, Benjamin; Escudero, Beatriz; Prakash, Mansi; Gesheva, Silvia; Liu, Guosheng; Huso, David L.; Franco, Sonia

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

COMMUNICATIONS BIOLOGY

IF5.1

2021-05-14

OAAI

Boleij, Annemarie; Fathi, Payam; Dalton, William; Park, Ben; Wu, Xinqun; Huso, David; Allen, Jawara; Besharati, Sepideh; Anders, Robert A.; Housseau, Franck; Mackenzie, Amanda E.; Jenkins, Laura; Milligan, Graeme.; Wu, Shaoguang; Sears, Cynthia L.

HMGA1 induces FGF-19 to foster tumor-stromal cell crosstalk and drive tumor progression in pancreatic ductal adenocarcinoma

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Chia, Lionel; Shuai, Shuai; Xian, Lingling; Kim, Jung-Hyun; Zhang, Ruitao; Huso, Tait; Huso, David; Cope, Leslie; Reddy, Karen; Resar, Linda

Oxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2019-05-01

OAAI

Habashi, Jennifer Pardo; MacFarlane, Elena Gallo; Bagirzadeh, Rustam; Bowen, Caitlin; Huso, Nicholas; Chen, Yichun; Bedja, Djahida; Creamer, Tyler J.; Rykiel, Graham; Manning, Maurice; Huso, David; Dietz, Harry C.

HMGA1 amplifies Wnt signaling and expands the intestinal stem cell compartment to drive premalignant polyposis in transgenic mice

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Xian, Lingling; Georgess, Dan; Luo, Li; Chia, Lionel; Gu, Qihua; Huso, Tait; Belton, Amy; Huso, David; Ewald, Andrew; Resar, Linda M. S.

HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche

NATURE COMMUNICATIONS

IF15.7

2017-04-28

OAAI

Xian, Lingling; Georgess, Dan; Huso, Tait; Cope, Leslie; Belton, Amy; Chang, Yu-Ting; Kuang, Wenyong; Gu, Qihua; Zhang, Xiaoyan; Senger, Stefania; Fasano, Alessio; Huso, David L.; Ewald, Andrew J.; Resar, Linda M. S.

A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-12-20

OAAI

Benjamin, Joel S.; Pilarowski, Genay O.; Carosso, Giovanni A.; Zhang, Li; Huso, David. L.; Goff, Loyal A.; Vernon, Hilary J.; Hansen, Kasper D.; Bjornsson, Hans T.

High mobility group A1 chromatin remodeling protein expands the intestinal stem cell compartment and Paneth cell niche through Wnt/β-catenin signaling and Sox9

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Xian, Lingling; Huso, Tait; Belton, Amy; Huso, David; Resar, Linda M. S.

Oncogenic BRAFV600E drives stem cell niche factors-independent growth and tumorigenic transformation in colon organoids

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Kang, Byunghak; In, Julie; Zachos, Nicholas; Huso, David; Maegawa, Shinji; Issa, Jean-Pierre; Easwaran, Hariharan; Baylin, Stephen B.

Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease

KIDNEY INTERNATIONAL

IF12.6

2016-07-01

OAAI

Cebotaru, Liudmila; Liu, Qiangni; Yanda, Murali K.; Boinot, Clement; Outeda, Patricia; Huso, David L.; Watnick, Terry; Guggino, William B.; Cebotaru, Valeriu

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis

CANCER RESEARCH

IF16.6

2016-04-14

OAAI

Housseau, Franck; Wu, Shaoguang; Wick, Elizabeth C.; Fan, Hongni; Wu, Xinqun; Llosa, Nicolas J.; Smith, Kellie N.; Tam, Ada; Ganguly, Sudipto; Wanyiri, Jane W.; Iyadorai, Thevambiga; Malik, Ausama A.; Roslani, April C.; Vadivelu, Jamunarani S.; Van Meerbeke, Sara; Huso, David L.; Pardoll, Drew M.; Sears, Cynthia L.

Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer

CANCER RESEARCH

IF16.6

2016-03-31

OAAI

Merino, Vanessa F.; Nguyen, Nguyen; Jin, Kideok; Sadik, Helen; Cho, Soonweng; Korangath, Preethi; Han, Liangfeng; Foster, Yolanda M. N.; Zhou, Xian C.; Zhang, Zhe; Connolly, Roisin M.; Stearns, Vered; Ali, Syed Z.; Adams, Christina; Chen, Qian; Pan, Duojia; Huso, David L.; Ordentlich, Peter; Brodie, Angela; Sukumar, Saraswati

Activation of Liver X Receptor/Retinoid X Receptor Pathway Ameliorates Liver Disease in Atp7B-/- (Wilson Disease) Mice

HEPATOLOGY

IF15.8

2016-02-22

OAAI

Hamilton, James P.; Koganti, Lahari; Muchenditsi, Abigael; Pendyala, Venkata S.; Huso, David; Hankin, Joseph; Murphy, Robert C.; Huster, Dominik; Merle, Uta; Mangels, Christopher; Yang, Nan; Potter, James J.; Mezey, Esteban; Lutsenko, Svetlana

Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2016-02-21

OAAI

Shields, Christina E. DeStefano; Van Meerbeke, Sara W.; Housseau, Franck; Wang, Hao; Huso, David L.; Casero, Robert A., Jr.; O'Hagan, Heather M.; Sears, Cynthia L.

Small Scale Renal Dosimetry for Alpha Particle Radiopharmaceutical Therapy of Metastatic Breast Cancer With 225Ac-7.16.4

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2015-11-01

PREAI

Josefsson, A.; Zhu, C.; Park, S.; Abou, D.; Song, H.; Huso, D.; Back, T.; Bruchertseifer, F.; Morgenstern, A.; Bolch, W. E.; Sgouros, G.; Hobbs, R. F.

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome

ELIFE

IF0

2015-10-27

OAAI

Doyle, Jefferson J.; Doyle, Alexander J.; Wilson, Nicole K.; Habashi, Jennifer P.; Bedja, Djahida; Whitworth, Ryan E.; Lindsay, Mark E.; Schoenhoff, Florian; Myers, Loretha; Huso, Nick; Bachir, Suha; Squires, Oliver; Rusholme, Benjamin; Ehsan, Hamid; Huso, David; Thomas, Craig J.; Caulfield, Mark J.; Van Eyk, Jennifer E.; Judge, Daniel P.; Dietz, Harry C.

Optimal definition of biological tumor volume using positron emission tomography in an animal model

EJNMMI RESEARCH

IF3

2015-10-21

OAAI

Wu, Ingrid; Wang, Hao; Huso, David; Wahl, Richard L.

Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis

CANCER DISCOVERY

IF33.3

2015-09-30

142

OAAI

Geis, Abby L.; Fan, Hongni; Wu, Xinqun; Wu, Shaoguang; Huso, David L.; Wolfe, Jaime L.; Sears, Cynthia L.; Pardoll, Drew M.; Housseau, Franck

Giant obscurins: Novel tumor and metastasis suppressors in breast cancer

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Kontrogianni-Konstantopoulos, Aikaterini; Shriver, Marey; Perry, Nicole; Stroka, Kimberly; Vitole, Michele; Huso, David; Martin, Stuart; Konstantopoulos, Konstantinos

Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Merino, Vanessa F.; Nguyen Nguyen; Sadik, Helen; Cho, Soonweng; Cope, Leslie; Zhou, Xian C.; Zhang, Zhe; Chen, Qian; Pan, Duojia; Huso, David L.; Ali, Syed; Adams, Christina; Gyorffy, Balazs; Sukumar, Saraswati

研究方向