Dwight H. Kono - Publications, H-index & Citations

Dwight H. Kono

The Scripps Research Institute

45H指数

177论文数

9.0K被引数

收录论文 43

发表时间

Crystalline silica exposure of genetically diverse mice exacerbates subclinical autoimmunity into systemic autoimmune disease phenotypes including inflammatory arthritis in female mice 遗传多样性小鼠的结晶二氧化硅暴露将亚临床自身免疫加剧为系统性自身免疫疾病表型，包括雌性小鼠的炎症性关节炎

Journal of Autoimmunity

IF7

2026-07-23

PREAI

Lisa M.F. Janssen; Caroline de Ocampo; Dwight H. Kono; Peter H.M. Hoet; K. Michael Pollard; Jessica M. Mayeux

Susceptibility to systemic autoimmunity rather than the presence of the HLA-DR4 peptide binding domain alone leads to severe inflammatory arthritis following inhalation of crystalline silica 对系统性自身免疫的易感性，而非仅存在HLA-DR4肽结合域，是吸入结晶型二氧化硅后引发严重炎性关节炎的原因。

Particle and Fibre Toxicology

IF8.2

2026-02-09

OAAI

Lisa M. F. Janssen; Caroline de Ocampo; Dwight H. Kono; Steven Ronsmans; Manosij Ghosh; Peter H. M. Hoet; K. Michael Pollard; Jessica M. Mayeux

Silica exposure as a driver of inflammatory arthritis: insights from genetically susceptible mouse models

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Janssen, Lisa M. F.; De Ocampo, Caroline; Kono, Dwight H.; Hoet, Peter H. M.; Pollard, Kenneth Michael; Mayeux, Jessica Marie

A novel mouse model of silicosis and silica-induced inflammatory arthritis.

JOURNAL OF IMMUNOLOGY

IF3.4

2024-05-01

PREAI

de Ocampo, Caroline; Mayeux, Jessica; Kono, Dwight; Pollard, Michael; Janssen, Lisa

Silicosis and silica-induced autoimmunity in multiple Collaborative Cross strains

JOURNAL OF IMMUNOLOGY

IF3.4

2024-05-01

PREAI

de Ocampo, Caroline; Mayeux, Jessica; Kono, Dwight; Pollard, Michael; Janssen, Lisa

The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-03-29

OAAI

Rimann, Ivo; Gonzalez-Quintial, Rosana; Baccala, Roberto; Kiosses, William B.; Teijaro, John R.; Parker, Christopher G.; Li, Xiaohong; Beutler, Bruce; Kono, Dwight H.; Theofilopoulos, Argyrios N.

Mechanisms of Environment-Induced Autoimmunity

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 61, 2021

IF0

2021-01-06

OAAI

Pollard, K. Michael; Cauvi, David M.; Mayeux, Jessica M.; Toomey, Christopher B.; Peiss, Amy K.; Hultman, Per; Kono, Dwight H.

Development of experimental silicosis in inbred and outbred mice depends on instillation volume

SCIENTIFIC REPORTS

IF3.9

2019-10-02

OAAI

Mayeux, Jessica M.; Kono, Dwight H.; Pollard, Kenneth Michael

Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse 在多样性远交小鼠中矽肺和二氧化硅诱导的自身免疫

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-04-26

OAAI

Mayeux, Jessica M.; Escalante, Gabriela M.; Christy, Joseph M.; Pawar, Rahul D.; Kono, Dwight H.; Pollard, Kenneth M.

Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN

JOURNAL OF IMMUNOLOGY

IF3.4

2017-12-01

OAAI

Pollard, K. Michael; Escalante, Gabriela M.; Huang, Hua; Haraldsson, Katarina M.; Hultman, Per; Christy, Joseph M.; Pawar, Rahul D.; Mayeux, Jessica M.; Gonzalez-Quintial, Rosana; Baccala, Roberto; Beutler, Bruce; Theofilopoulos, Argyrios N.; Kono, Dwight H.

The multiple pathways to autoimmunity

NATURE IMMUNOLOGY

IF27.6

2017-06-20

427

OAAI

Theofilopoulos, Argyrios N.; Kono, Dwight H.; Baccala, Roberto

TLRs and interferons: a central paradigm in autoimmunity

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2013-12-01

OAAI

Kono, Dwight H.; Baccala, Roberto; Theofilopoulos, Argyrios N.

Role of Nucleic Acid-Sensing TLRs in Diverse Autoantibody Specificities and Anti-Nuclear Antibody-Producing B Cells

JOURNAL OF IMMUNOLOGY

IF3.4

2013-05-15

OAAI

Koh, Yi Ting; Scatizzi, John C.; Gahan, Jennifer D.; Lawson, Brian R.; Baccala, Roberto; Pollard, K. Michael; Beutler, Bruce A.; Theofilopoulos, Argyrios N.; Kono, Dwight H.

Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-02-04

115

OAAI

Baccala, Roberto; Gonzalez-Quintial, Rosana; Blasius, Amanda L.; Rimann, Ivo; Ozato, Keiko; Kono, Dwight H.; Beutler, Bruce; Theofilopoulos, Argyrios N.

Anti-IFN-α/β Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice

JOURNAL OF IMMUNOLOGY

IF3.4

2012-12-15

OAAI

Baccala, Roberto; Gonzalez-Quintial, Rosana; Schreiber, Robert D.; Lawson, Brian R.; Kono, Dwight H.; Theofilopoulos, Argyrios N.

Animal models used to examine the role of the environment in the development of autoimmune disease: Findings from an NIEHS Expert Panel Workshop

JOURNAL OF AUTOIMMUNITY

IF7

2012-12-01

OAAI

Germolec, Dori; Kono, Dwight H.; Pfau, Jean C.; Pollard, K. Michael

Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity

JOURNAL OF AUTOIMMUNITY

IF7

2012-12-01

OAAI

Pollard, K. Michael; Hultman, Per; Toomey, Christopher B.; Cauvi, David M.; Hoffman, Hal M.; Hamel, John C.; Kono, Dwight H.

MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-11-08

OAAI

Groenwall, Caroline; Chen, Yifang; Vas, Jaya; Khanna, Sahil; Thiel, Steffen; Corr, Maripat; Kono, Dwight H.; Silverman, Gregg J.

Mast cell function is not altered by Coronin-1A deficiency

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2010-07-19

OAAI

Arandjelovic, Sanja; Wickramarachchi, Dilki; Hemmers, Saskia; Leming, Sunamita S.; Kono, Dwight H.; Mowen, Kerri A.

Deletion of IgG-Switched Autoreactive B Cells and Defects in Faslpr Lupus Mice

JOURNAL OF IMMUNOLOGY

IF3.4

2010-07-15

OAAI

Ait-Azzouzene, Djemel; Kono, Dwight H.; Gonzalez-Quintial, Rosana; McHeyzer-Williams, Louise J.; Lim, Min; Wickramarachchi, Dilki; Gerdes, Tobias; Gavin, Amanda L.; Skog, Patrick; McHeyzer-Williams, Michael G.; Nemazee, David; Theofilopoulos, Argyrios N.

研究方向