Argyrios N. Theofilopoulos

Scripps Clinic and Research Foundation

77H指数

336论文数

2.2W被引数

收录论文 69

发表时间

Machine learning-based identification of a transcriptomic blood signature discriminating between systemic autoimmunity and infection 基于机器学习的转录组血液特征识别，用于区分系统性自身免疫和感染

Med

IF11.8

2025-09-05

PREAI

Kleio-Maria Verrou; Nikolaos I. Vlachogiannis; Argyrios N. Theofilopoulos; Maria Tektonidou; Georgios Kollias; Christoforos Nikolaou; Petros P. Sfikakis

Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors

OCULAR SURFACE

IF5.6

2024-04-01

OAAI

Stern, Michael E.; Theofilopoulos, Argyrios N.; Steven, Philipp; Niederkorn, Jerry Y.; Fox, Robert; Calonge, Margarita; Scheid, Christof; Pflugfelder, Stephen C.

Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity

NATURE CHEMICAL BIOLOGY

IF13.7

2024-01-08

OAAI

Chiu, Tzu-Yuan; Lazar, Daniel C.; Wang, Wesley W.; Wozniak, Jacob M.; Jadhav, Appaso M.; Li, Weichao; Gazaniga, Nathalia; Theofilopoulos, Argyrios N.; Teijaro, John R.; Parker, Christopher G.

The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-03-29

OAAI

Rimann, Ivo; Gonzalez-Quintial, Rosana; Baccala, Roberto; Kiosses, William B.; Teijaro, John R.; Parker, Christopher G.; Li, Xiaohong; Beutler, Bruce; Kono, Dwight H.; Theofilopoulos, Argyrios N.

Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN

JOURNAL OF IMMUNOLOGY

IF3.4

2017-12-01

OAAI

Pollard, K. Michael; Escalante, Gabriela M.; Huang, Hua; Haraldsson, Katarina M.; Hultman, Per; Christy, Joseph M.; Pawar, Rahul D.; Mayeux, Jessica M.; Gonzalez-Quintial, Rosana; Baccala, Roberto; Beutler, Bruce; Theofilopoulos, Argyrios N.; Kono, Dwight H.

The multiple pathways to autoimmunity

NATURE IMMUNOLOGY

IF27.6

2017-06-20

427

OAAI

Theofilopoulos, Argyrios N.; Kono, Dwight H.; Baccala, Roberto

Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-09-23

OAAI

Wang, Rongsheng E.; Wang, Ying; Zhang, Yuhan; Gabrelow, Chase; Zhang, Yong; Chi, Victor; Fu, Qiangwei; Luo, Xiaozhou; Wang, Danling; Joseph, Sean; Johnson, Kristen; Chatterjee, Arnab K.; Wright, Timothy M.; Nguyen-Tran, Van T. B.; Teijaro, John; Theofilopoulos, Argyrios N.; Schultz, Peter G.; Wang, Feng

An agonist antibody that blocks autoimmunity by inducing anti-inflammatory macrophages

FASEB JOURNAL

IF4.2

2015-10-19

OAAI

Han, Kyung Ho; Gonzalez-Quintial, Rosana; Peng, Yingjie; Baccala, Roberto; Theofilopoulos, Argyrios N.; Lerner, Richard A.

Type I interferon is a therapeutic target for virus-induced lethal vascular damage

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-06-02

OAAI

Baccala, Roberto; Welch, Megan J.; Gonzalez-Quintial, Rosana; Walsh, Kevin B.; Teijaro, John R.; Nguyen, Anthony; Ng, Cherie T.; Sullivan, Brian M.; Zarpellon, Alessandro; Ruggeri, Zaverio M.; de la Torre, Juan Carlos; Theofilopoulos, Argyrios N.; Oldstone, Michael B. A.

TLRs and interferons: a central paradigm in autoimmunity

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2013-12-01

OAAI

Kono, Dwight H.; Baccala, Roberto; Theofilopoulos, Argyrios N.

Role of Nucleic Acid-Sensing TLRs in Diverse Autoantibody Specificities and Anti-Nuclear Antibody-Producing B Cells

JOURNAL OF IMMUNOLOGY

IF3.4

2013-05-15

OAAI

Koh, Yi Ting; Scatizzi, John C.; Gahan, Jennifer D.; Lawson, Brian R.; Baccala, Roberto; Pollard, K. Michael; Beutler, Bruce A.; Theofilopoulos, Argyrios N.; Kono, Dwight H.

Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-02-04

115

OAAI

Baccala, Roberto; Gonzalez-Quintial, Rosana; Blasius, Amanda L.; Rimann, Ivo; Ozato, Keiko; Kono, Dwight H.; Beutler, Bruce; Theofilopoulos, Argyrios N.

Anti-IFN-α/β Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice

JOURNAL OF IMMUNOLOGY

IF3.4

2012-12-15

OAAI

Baccala, Roberto; Gonzalez-Quintial, Rosana; Schreiber, Robert D.; Lawson, Brian R.; Kono, Dwight H.; Theofilopoulos, Argyrios N.

Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-07-16

OAAI

Brandl, Katharina; Tomisato, Wataru; Li, Xiaohong; Neppl, Christina; Pirie, Elaine; Falk, Werner; Xia, Yu; Moresco, Eva Marie Y.; Baccala, Roberto; Theofilopoulos, Argyrios N.; Schnabl, Bernd; Beutler, Bruce

Deletion of IgG-Switched Autoreactive B Cells and Defects in Faslpr Lupus Mice

JOURNAL OF IMMUNOLOGY

IF3.4

2010-07-15

OAAI

Ait-Azzouzene, Djemel; Kono, Dwight H.; Gonzalez-Quintial, Rosana; McHeyzer-Williams, Louise J.; Lim, Min; Wickramarachchi, Dilki; Gerdes, Tobias; Gavin, Amanda L.; Skog, Patrick; McHeyzer-Williams, Michael G.; Nemazee, David; Theofilopoulos, Argyrios N.

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence

NATURE IMMUNOLOGY

IF27.6

2010-02-28

OAAI

Berger, Michael; Krebs, Philippe; Crozat, Karine; Li, Xiaohong; Croker, Ben A.; Siggs, Owen M.; Popkin, Daniel; Du, Xin; Lawson, Brian R.; Theofilopoulos, Argyrios N.; Xia, Yu; Khovananth, Kevin; Moresco, Eva Marie Y.; Satoh, Takashi; Takeuchi, Osamu; Akira, Shizuo; Beutler, Bruce

Sensors of the innate immune system: their link to rheumatic diseases

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2010-02-09

OAAI

Theofilopoulos, Argyrios N.; Gonzalez-Quintial, Rosana; Lawson, Brian R.; Koh, Yi T.; Stern, Michael E.; Kono, Dwight H.; Beutler, Bruce; Baccala, Roberto

Inhibition of lupus by genetic alteration of the interferon-α/β receptor

AUTOIMMUNITY

IF3.1

2009-08-03

PREAI

Kono, DH; Baccala, R; Theofilopoulos, AN

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2009-07-21

155

OAAI

Kono, Dwight H.; Haraldsson, M. Katarina; Lawson, Brian R.; Pollard, K. Michael; Koh, Yi Ting; Du, Xin; Arnold, Carrie N.; Baccala, Roberto; Silverman, Gregg J.; Beutler, Bruce A.; Theofilopoulos, Argyrios N.

Sensors of the innate immune system: their mode of action

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2009-07-14

115

PREAI

Baccala, Roberto; Gonzalez-Quintial, Rosana; Lawson, Brian R.; Stern, Michael E.; Kono, Dwight H.; Beutler, Bruce; Theofilopoulos, Argyrios N.

研究方向