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收藏Notch activation is an early and critical event during T-cell leukemogenesis in Ikaros-deficient mice
Dumortier, A; Jeannet, R; Kirstetter, P; Kleinmann, E; Sellars, M; dos Santos, NR; Thibault, C; Barths, J; Ghysdael, J; Punt, JA; Kastner, P; Chan, S 分享 收藏 Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL利用MYB依赖性TAL1 5' 超级增强子进行t-all的靶向治疗Smith, Charlotte; Touzart, Aurore; Simonin, Mathieu; Tran-Quang, Christine; Hypolite, Guillaume; Latiri, Mehdi; Andrieu, Guillaume P.; Balducci, Estelle; Dourthe, Marie-emilie; Goyal, Ashish; Huguet, Francoise; Petit, Arnaud; Ifrah, Norbert; Baruchel, Andre; Dombret, Herve; Macintyre, Elizabeth; Plass, Christoph; Ghysdael, Jacques; Boissel, Nicolas; Asnafi, Vahid 分享 收藏 Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive (BCR::ABL plus ) Acute Lymphoblastic Leukemia (ALL)Berrou, Jeannig; Dupont, Melanie; Djamai, Hanane; Adiceam, Emilie; Parietti, Veronique; Kaci, Anna; Clappier, Emmanuelle; Cayuela, Jean-Michel; Baruchel, Andre; Paublant, Fabrice; Prudent, Renaud; Ghysdael, Jacques; Gardin, Claude; Dombret, Herve; Braun, Thorsten 分享 收藏 AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naive and Treatment-Resistant LeukemiaTirado-Gonzalez, Irene; Descot, Arnaud; Soetopo, Devona; Nevmerzhitskaya, Aleksandra; Schaeffer, Alexander; Kur, Ivan-Maximilano; Czlonka, Ewelina; Wachtel, Carolin; Tsoukala, Ioanna; Mueller, Luise; Schaefer, Anna-Lena; Weitmann, Maresa; Dinse, Petra; Alberto, Emily; Buck, Michele C.; Landry, Jonathan Jm; Baying, Bianka; Slotta-Huspenina, Julia; Roesler, Jenny; Harter, Patrick N.; Kubasch, Anne-Sophie; Meinel, Jorn; Elwakeel, Eiman; Strack, Elisabeth; Quang, Christine Tran; Abdel-Wahab, Omar; Schmitz, Marc; Weigert, Andreas; Schmid, Tobias; Platzbecker, Uwe; Benes, Vladimir; Ghysdael, Jacques; Bonig, Halvard; Goetze, Katharina S.; Rothlin, Carla, V; Ghosh, Sourav; Medyouf, Hind 分享 收藏 Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroupTouzart, Aurore; Mayakonda, Anand; Smith, Charlotte; Hey, Joschka; Toth, Reka; Cieslak, Agata; Andrieu, Guillaume P.; Quang, Christine Tran; Latiri, Mehdi; Ghysdael, Jacques; Spicuglia, Salvatore; Dombret, Herve; Ifrah, Norbert; Macintyre, Elizabeth; Lutsik, Pavlo; Boissel, Nicolas; Plass, Christoph; Asnafi, Vahid 分享 收藏 Novel Intergenically Spliced Chimera, NFATC3-PLA2G15, Is Associated with Aggressive T-ALL Biology and OutcomeBond, Jonathan; Quang, Christine Tran; Hypolite, Guillaume; Belhocine, Mohamed; Bergon, Aurelie; Cordonnier, Gaelle; Ghysdael, Jacques; Macintyre, Elizabeth; Boissel, Nicolas; Spicuglia, Salvatore; Asnafi, Vahid 分享 收藏 分享 收藏 Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell LeukemiaTrinquand, Amelie; dos Santos, Nuno R.; Quang, Christine Tran; Rocchetti, Francesca; Zaniboni, Benedetta; Belhocine, Mohamed; de Jesus, Cindy Da Costa; Lhermitte, Ludovic; Tesio, Melania; Dussiot, Michael; Cosset, Francois-Loic; Verhoeyen, Els; Pflumio, Francoise; Ifrah, Norbert; Dombret, Herve; Spicuglia, Salvatore; Chatenoud, Lucienne; Gross, David-Alexandre; Hermine, Olivier; Macintyre, Elizabeth; Ghysdael, Jacques; Asnafi, Vahid 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progressionUzan, Benjamin; Poglio, Sandrine; Gerby, Bastien; Wu, Ching-Lien; Gross, Julia; Armstrong, Florence; Calvo, Julien; Cahu, Xavier; Deswarte, Caroline; Dumont, Florent; Passaro, Diana; Besnard-Guerin, Corinne; Leblanc, Thierry; Baruchel, Andre; Landman-Parker, Judith; Ballerini, Paola; Baud, Veronique; Ghysdael, Jacques; Baleydier, Frederic; Porteu, Francoise; Pflumio, Francoise 分享 收藏 分享 收藏 Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 InhibitorsWaibel, Michaela; Solomon, Vanessa S.; Knight, Deborah A.; Ralli, Rachael A.; Kim, Sang-Kyu; Banks, Kellie-Marie; Vidacs, Eva; Virely, Clemence; Sia, Keith C. S.; Bracken, Lauryn S.; Collins-Underwood, Racquel; Drenberg, Christina; Ramsey, Laura B.; Meyer, Sara C.; Takiguchi, Megumi; Dickins, Ross A.; Levine, Ross; Ghysdael, Jacques; Dawson, Mark A.; Lock, Richard B.; Mullighan, Charles G.; Johnstone, Ricky W. 分享 收藏 分享 收藏 Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemiaGachet, S.; Genesca, E.; Passaro, D.; Irigoyen, M.; Alcalde, H.; Clemenson, C.; Poglio, S.; Pflumio, F.; Janin, A.; Lasgi, C.; Dodier, S.; Soyer, M.; Dumenil, G.; Ghysdael, J. 分享 收藏 Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemiaVirely, C.; Moulin, S.; Cobaleda, C.; Lasgi, C.; Alberdi, A.; Soulier, J.; Sigaux, F.; Chan, S.; Kastner, P.; Ghysdael, J. 分享 收藏 RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci (vol 10, pg 655, 2009)Hewitt, Susannah L.; Yin, Bu; Ji, Yanhong; Chaumeil, Julie; Marszalek, Katarzyna; Tenthorey, Jeannette; Salvagiotto, Giorgia; Steinel, Natalie; Ramsey, Laura B.; Ghysdael, Jacques; Farrar, Michael A.; Sleckman, Barry P.; Schatz, David G.; Busslinger, Meinrad; Bassing, Craig H.; Skok, Jane A. 分享 收藏 RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci (vol 10, pg 655, 2009)Hewitt, Susannah L.; Yin, Bu; Ji, Yanhong; Chaumeil, Julie; Marszalek, Katarzyna; Tenthorey, Jeannette; Salvagiotto, Giorgia; Steinel, Natalie; Ramsey, Laura B.; Ghysdael, Jacques; Farrar, Michael A.; Sleckman, Barry P.; Schatz, David G.; Busslinger, Meinrad; Bassing, Craig H.; Skok, Jane A. 分享 收藏 
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