未登录 Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments Martinelli, Paola; Schaaf, Otmar; Mantoulidis, Andreas; Martin, Laetitia J.; Fuchs, Julian E.; Bader, Gerd; Gollner, Andreas; Wolkerstorfer, Bernhard; Rogers, Catherine; Balikci, Esra; Lipp, Jesse J.; Mischerikow, Nikolai; Doebel, Sandra; Gerstberger, Thomas; Sommergruber, Wolfgang; Huber, Kilian V. M.; Boettcher, Jark 分享 收藏
PI3Kβ inhibition enhances ALK-inhibitor sensitivity in ALK-rearranged lung cancer Talwelkar, Sarang S.; Mayranpaa, Mikko I.; Schuler, Julia; Linnavirta, Nora; Hemmes, Annabrita; Adinolfi, Simone; Kankainen, Matti; Sommergruber, Wolfgang; Levonen, Anna-Liisa; Rasanen, Jari; Knuuttila, Aija; Verschuren, Emmy W.; Wennerberg, Krister 分享 收藏
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Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M.; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J.; Schmid, Ralph A.; Hall, Sean R. R. 分享 收藏
Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages 基质成纤维细胞在正常结肠和结直肠癌中形成髓样表型并诱导巨噬细胞中CD163和CCL2的表达 Stadler, Mira; Pudelko, Karoline; Biermeier, Alexander; Walterskirchen, Natalie; Gaigneaux, Anthoula; Weindorfer, Claudia; Harrer, Nathalie; Klett, Hagen; Hengstschlaeger, Markus; Schueler, Julia; Sommergruber, Wolfgang; Oehler, Rudolf; Bergmann, Michael; Letellier, Elisabeth; Dolznig, Helmut 分享 收藏
KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth Raho, Susanna; Capobianco, Loredana; Malivindi, Rocco; Vozza, Angelo; Piazzolla, Carmela; De Leonardis, Francesco; Gorgoglione, Ruggiero; Scarcia, Pasquale; Pezzuto, Francesca; Agrimi, Gennaro; Barile, Simona N.; Pisano, Isabella; Reshkin, Stephan J.; Greco, Maria R.; Cardone, Rosa A.; Rago, Vittoria; Li, Yuan; Marobbio, Carlo M. T.; Sommergruber, Wolfgang; Riley, Christopher L.; Lasorsa, Francesco M.; Mills, Edward; Vegliante, Maria C.; De Benedetto, Giuseppe E.; Fratantonio, Deborah; Palmieri, Luigi; Dolce, Vincenza; Fiermonte, Giuseppe 分享 收藏
Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer 癌症相关成纤维细胞衍生的WNT2增加结肠癌的肿瘤血管生成 Unterleuthner, Daniela; Neuhold, Patrick; Schwarz, Katharina; Janker, Lukas; Neuditschko, Benjamin; Nivarthi, Harini; Crncec, Ilija; Kramer, Nina; Unger, Christine; Hengstschlaeger, Markus; Eferl, Robert; Moriggl, Richard; Sommergruber, Wolfgang; Gerner, Christopher; Dolznig, Helmut 分享 收藏
SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines Ehrenhoefer-Woelfer, Katharina; Puchner, Teresa; Schwarz, Cornelia; Rippka, Janine; Blaha-Ostermann, Silvia; Strobl, Ursula; Hoermann, Alexandra; Bader, Gerd; Kornigg, Stefan; Zahn, Stephan; Sommergruber, Wolfgang; Schweifer, Norbert; Zichner, Thomas; Schlattl, Andreas; Neumueller, Ralph A.; Shi, Junwei; Vakoc, Christopher R.; Koegl, Manfred; Petronczki, Mark; Kraut, Norbert; Pearson, Mark A.; Woehrle, Simon 分享 收藏
Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis Weinstabl, Harald; Treu, Matthias; Rinnenthal, Joerg; Zahn, Stephan K.; Ettmayer, Peter; Bader, Gerd; Dahmann, Georg; Kessler, Dirk; Rumpel, Klaus; Mischerikow, Nikolai; Savarese, Fabio; Gerstberger, Thomas; Mayer, Moriz; Zoephel, Andreas; Schnitzer, Renate; Sommergruber, Wolfgang; Martinelli, Paola; Arnhof, Heribert; Peric-Simov, Biljana; Hofbauer, Karin S.; Garavel, Geraldine; Scherbantin, Yvonne; Mitzner, Sophie; Fett, Thomas N.; Scholz, Guido; Bruchhaus, Jens; Burkard, Michelle; Kousek, Roland; Ciftci, Tuncay; Sharps, Bernadette; Schrenk, Andreas; Harrer, Christoph; Haerinsg, Daniela; Wolkerstorfer, Bernhard; Zhang, Xuechun; Lv, Xiaobing; Du, Alicia; Li, Dongyang; Li, Yali; Quant, Jens; Pearson, Mark; McConnell, Darryl B. 分享 收藏
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SMARCA4 is a selective vulnerability in SMARCA2-deficient esophageal squamous cell carcinoma cell lines Ehrenhoefer-Woelfer, Katharina; Puchner, Teresa; Blaha-Ostermann, Silvia; Hoermann, Alexandra; Sommergruber, Wolfgang; Schweifer, Norbert; Zichner, Thomas; Schlattl, Andreas; Neumueller, Ralph A.; Koegl, Manfred; Petronczki, Mark P.; Pearson, Mark; Woehrle, Simon 分享 收藏
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3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment Rebelo, Sofia P.; Pinto, Catarina; Martins, Tatiana R.; Harrer, Nathalie; Estrada, Marta F.; Loza-Alvarez, Pablo; Cabecadas, Jose; Alves, Paula M.; Gualda, Emilio J.; Sommergruber, Wolfgang; Brito, Catarina 分享 收藏
Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours Narhi, Katja; Nagaraj, Ashwini S.; Parri, Elina; Turkki, Riku; van Duijn, Petra W.; Hemmes, Annabrita; Lahtela, Jenni; Uotinen, Virva; Mayranpaa, Mikko I.; Salmenkivi, Kaisa; Rasanen, Jari; Linder, Nina; Trapman, Jan; Rannikko, Antti; Kallioniemi, Olli; Af Hallstrom, Taija M.; Lundin, Johan; Sommergruber, Wolfgang; Anders, Simon; Verschuren, Emmy W. 分享 收藏
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Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression Kramer, N.; Schmoellerl, J.; Unger, C.; Nivarthi, H.; Rudisch, A.; Unterleuthner, D.; Scherzer, M.; Riedl, A.; Artaker, M.; Crncec, I.; Lenhardt, D.; Schwarz, T.; Prieler, B.; Han, X.; Hengstschaelger, M.; Schueler, J.; Eferl, R.; Moriggl, R.; Sommergruber, W.; Dolznig, H. 分享 收藏
Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms Unger, C.; Kramer, N.; Unterleuthner, D.; Scherzer, M.; Burian, A.; Rudisch, A.; Stadler, M.; Schlederer, M.; Lenhardt, D.; Riedl, A.; Walter, S.; Wernitznig, A.; Kenner, L.; Hengstschlger, M.; Schler, J.; Sommergruber, W.; Dolznig, H. 分享 收藏
3D tumor models in bioreactors recapitulate microenvironment and disease progression Santo, Vitor E.; Estrada, Marta F.; Rebelo, Sofia P.; Abreu, Sofia; Pinto, Catarina; Anderson, Elizabeth; Sommergruber, Wolfgang; Alves, Paula; Boghaert, Erwin; Brito, Catarina 分享 收藏
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Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery Stock, Kristin; Estrada, Marta F.; Vidic, Suzana; Gjerde, Kjersti; Rudisch, Albin; Santo, Vitor E.; Barbier, Michael; Blom, Sami; Arundkar, Sharath C.; Selvam, Irwin; Osswald, Annika; Stein, Yan; Gruenewald, Sylvia; Brito, Catarina; van Weerden, Wytske; Rotter, Varda; Boghaert, Erwin; Oren, Moshe; Sommergruber, Wolfgang; Chong, Yolanda; de Hoogt, Ronald; Graeser, Ralph 分享 收藏
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