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O

O. Saavedra Santa Gadea

vall d'hebron institut d'oncologia (vhio)
H指数:4
被引数:70

个人简介

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教育背景

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工作经历

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荣誉奖项

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Leveraging innate and adaptive immunity with AFM24 and atezolizumab in metastatic gastric cancer

利用AFM24和atezolizumab增强固有免疫和适应性免疫在转移性胃癌中的应用

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Santa Gadea, O. Saavedra; Oberoi, A.; Lopez, J. S.; Cervantes, A.; Ponz-Sarvise, M.; Kim, H. R.; El-Khoueiry, A. B.; Shim, B.; Kim, J. W.; Boni, V.; Lugowska, I.; Szczylik, C.; Rogowski, W.; Mandziuk, S.; Ramlau, R.; Gaertner, U.; Lutkewitz, S.; Schuetz, D.; Emig, M.; Morales-Espinosa, D.
Debio 0123+carboplatin (CP) for patients (pts) with advanced solid tumors: Safety, preliminary efficacy and determination of recommended phase II dose (RP2D)

Debio 0123+顺铂（CP）用于晚期实体瘤患者的治疗：安全性、初步疗效及推荐II期剂量的确定（RP2D）

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Gelderblom, H.; Gadea, O. Saavedra Santa; Jalving, M.; Desar, I.; Gietema, J. A.; Oberoi, A.; Van Herpen, C.; Kroep, J. R.; Franzen, R. Frederiksen; Bellon, A.; Micallef, S.; Tat, T.; Dozio, V.; Luong, N.; Imedio, E. Rodrigo
A phase I/II study of CFT1946, a novel BIDAC degrader targeting mutant BRAF V600 solid tumors including metastatic colorectal cancer (CRC) in combination with cetuximab
ANNALS OF ONCOLOGY
IF65.4
2024-06-010
PRE
Vieito Villar, M.; McKean, M.; Spira, A.; Rosen, E.; Rodon, J.; Moreno, V.; Gambardella, V.; Saavedra Santa Gadea, O.; Cousin, S.; Cassier, P.; Korakis, I.; Van Tine, B. A.; Wang, J. S.; Ma, V. T-L.; Elez Fernandez, M. E.; Pelster, M.; Hinojosa, E.; Lobbardi, R.; Hurh, E.; Buchbinder, E.
An investigator-initiated phase I study to assess the safety and tolerability of ex vivo next-generation neoantigen-selected tumor-infiltrating lymphocyte (TIL) therapy in advanced immune checkpoint blockade (ICB) resistant solid tumors (NEXTGENTIL-ACT)

研究者启动的I期研究，以评估体外下一代新抗原选择的肿瘤浸润淋巴细胞 (TIL) 疗法在晚期免疫检查点阻断 (ICB) 耐药实体瘤中的安全性和耐受性 (nextgentil-act)

ANNALS OF ONCOLOGY
IF65.4
2023-10-010
PRE
Galvao, V.; Palomero, J.; Creus-Gonzalez, I.; Lostes Bardaji, M. J.; Lozano-Rabella, M.; Garcia-Garijo, A.; Yuste, A.; Rodriguez, L.; Villalobos Alberu, X.; Rotxes, M.; Vieito Villar, M.; Santa Gadea, O. Saavedra; Alonso, G.; Brana, I.; Munoz-Couselo, E.; Querol, S.; Tabernero, J.; Martin-Lluesma, S.; Gros, A.; Garralda, E.
Single-center retrospective analysis of patients with brain metastases included in early phase clinical trials
ANNALS OF ONCOLOGY
IF65.4
2023-10-010
OA
Pretelli, G.; Rojas Laimito, K. I.; Alonso, G.; Lostes Bardaji, M. J.; Hernando Calvo, A.; Galvao, V.; Oberoi, A.; Ortega Morillo, B.; Santa Gadea, O. Saavedra; Ginard Moya, J.; Saura Manich, C.; Elez Fernandez, M. E.; Ortiz, C.; Munoz Couselo, E.; Brana, I.; Callejo Perez, A.; Carles Galceran, J.; Felip, E.; Garralda, E.; Vieito Villar, M.
Characterization of germline HLA genotypes in patients (pts) with solid tumors treated with immunotherapy

免疫治疗实体瘤患者 (pts) 的生殖系HLA基因型特征

ANNALS OF ONCOLOGY
IF65.4
2023-10-010
OA
Laimito, K. I. Rojas; Villar, M. Vieito; Hernandez, M. A. Moya; Pretelli, G.; Bardaji, M. J. Lostes; Gadea, O. Saavedra Santa; Calvo, A. Hernando; Galvao, V.; Oberoi, A.; Alonso, G.; Brana, I.; Moya, J. Ginard; Argota, I. Baraibar; Manich, C. Saura; Couselo, E. Munoz; Macarulla, T.; Duran, C. Garcia; Galceran, J. Carles; Tabernero, J.; Garralda, E.
AFM24 AND ATEZOLIZUMAB COMBINATION IN PATIENTS WITH ADVANCED EPIDERMAL GROWTH FACTOR RECEPTOR-EXPRESSING (EGFR+) SOLID TUMORS: INITIAL RESULTS FROM THE PHASE 1 DOSEESCALATION STUDY
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-11-070
OA
Saavedra Santa Gadea, Omar; Morales-Espinosa, Daniela; Lopez, Juanita; Christenson, Eric; El-Khoueiry, Anthony; Cervantes, Andres; Raab, Christa; Gartner, Ulrike; Pietzko, Kerstin; Kohlhas, Laura; Schutz, Daniel; Hintzen, Gabriele; Ravenstijn, Paulien; Emig, Michael; Nava-Parada, Pilar
Genomic alterations in epigenetic modifiers and response to epigenetic-targeted agents (ETAs) in patients (pts) with recurrent/metastatic (R/M) salivary gland tumours (SGTs)
ANNALS OF ONCOLOGY
IF65.4
2022-09-010
OAAI
Rezqallah Aron, M. A.; Hernando-Calvo, A.; Galvao de Aguiar, V.; Saavedra Santa Gadea, O.; Assaf Pastrana, J. D.; Lostes Bardaji, M. J.; Rojas Laimito, K. I.; Aguilar Izquierdo, S.; Berche, R.; Tian, T.; Bescos, C.; Lorente, J.; Giralt, J.; Temprana-Salvador, J.; Alberola, M.; Dienstmann, R.; Felip, E.; Garralda, E.; Vieito Villar, M.; Brana, I.
The HLA I composite score and VHIO immune gene-expression signature (VIGex) as selection tools to explore the tumor microenvironment (TME) in patients (pts) treated with immunotherapy (IT)
ANNALS OF ONCOLOGY
IF65.4
2022-09-010
OA
Saavedra Santa Gadea, O.; Vila Casadesus, M.; Mirallas, O.; Calvo, A. H.; Ros Montana, F. J.; Baraibar Argota, I.; Suarez Rodriguez, C.; Oberoi, A.; Morales Barrera, R.; Iranzo Gomez, P.; Alonso, G.; Brana, I.; Cabrera Navarro, A.; Hernandez-Illan, E.; Vieito Villar, M.; Elez Fernandez, M. E.; Gonzalez Rodriguez, M.; Felip, E.; Garralda, E.; Vivancos, A.
Circulating tumor DNA (ctDNA) next generation sequencing (NGS): Molecular prescreening for tailoring treatment in clinical trials
ANNALS OF ONCOLOGY
IF65.4
2021-10-011
OA
Alonso, G.; Aguilar, S.; Ros Montana, F. J.; Verdaguer, H.; Callejo Perez, A.; Brana, I.; Baraibar Argota, I.; Iranzo Gomez, P.; Santa Gadea, O. Saavedra; Salva Ballabrera, F.; Acosta Eyzaguirre, D. A.; Vieito Villar, M.; Garcia Torralba, E.; Wornham, N. A.; Faull, I.; Tabernero, J.; Felip, E.; Elez, E.; Macarulla Mercade, T.; Garralda, E.
Rescue chemotherapy (CT) after immune-oncology (IO) drugs in patients (pts) with refractory solid tumours: A propensity score (PS) matched cohort study
ANNALS OF ONCOLOGY
IF65.4
2020-09-010
OAAI
Galvao, V.; Ros Montana, F. J.; Matos, I.; Viaplana, C.; Villacampa Javierre, G.; Brana, I.; Azaro Pedrazzoli, A. B.; Vieito Villar, M.; Santa Gadea, O. Saavedra; Alonso Casal, G.; Hernando-Calvo, A.; Carles, J.; Macarulla Mercade, T.; Munoz Couselo, E.; Elez, E.; Felip, E.; Tabernero, J.; Dienstmann, R.; Oliveira, M.; Garralda, E.
Nutritional status (NS) as a strong predictor for immunotherapy (IT) outcome in recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) patients (pts)
ANNALS OF ONCOLOGY
IF65.4
2020-09-010
OAAI
Hernando-Calvo, A.; Mirallas, O.; Marmolejo Castaneda, D. H.; Vieito, M.; Santa Gadea, O. Saavedra; Gardeazabal, I.; Villacampa Javierre, G.; Aguilar, S.; Martin Liberal, J.; Bescos, C.; Lorente, J.; Giralt, J.; Benavente, S.; Fuentes, J. F.; Temprana-Salvador, J.; Alberola, M.; Dienstmann, R.; Garralda, E.; Felip, E.; Brana, I.
Limited efficacy of immunotherapy combination regimens in patients with unselected cold tumours enrolled in early clinical trials
ANNALS OF ONCOLOGY
IF65.4
2020-09-010
OAAI
Santa Gadea, O. Saavedra; Hernando-Calvo, A.; Berche, R.; Matos, I.; Gardeazabal, I.; Azaro Pedrazzoli, A. B.; Vieito Villar, M.; Brana, I.; Alonso Casal, G.; Galvao de Aguiar, V.; Pedrola, A.; Argiles Martinez, G.; Macarulla Mercade, T.; Capdevila, J.; Cedres, S.; Oaknin, A.; Elez, E.; Tabernero, J.; Dienstmann, R.; Garralda, E.

研究方向

暂未获取到该数据
E
Elena Garralda
H 指数:46论文数:729被引数:1.0万
M
María Vieito
H 指数:25论文数:314被引数:2,189
I
Irene Braña
H 指数:47论文数:373被引数:1.2万
J
Josep Tabernero
H 指数:146论文数:2,711被引数:12.6万
R
Rodrigo Dienstmann
H 指数:57论文数:651被引数:2.0万
A
Alberto Hernando‐Calvo
H 指数:10论文数:100被引数:354
A
A. Oberoi
H 指数:5论文数:37被引数:121
G
G. Alonso Casal
H 指数:3论文数:47被引数:35
E
Enriqueta Felip
H 指数:129论文数:1,499被引数:11.0万
G
Guzmán Alonso
H 指数:13论文数:82被引数:986