未登录 Scientific and Regulatory Policy Committee Points to Consider*: Sample Selection, Assay Design, Data Generation and Interpretation, and Reporting Practices for Chromogenic Immunohistochemical (IHC) Assays in Nonclinical Drug Development 科学和监管政策委员会考虑要点*: 样本选择、检测试剂盒设计、数据生成与解释以及报告实践，用于非临床药物开发中的显色免疫组织化学（IHC）检测试剂盒 Aeffner, Famke; Bolon, Brad; Boyle, Molly H.; Buetow, Bernard S.; Forest, Thomas; Janardhan, Kyathanahalli; Mansfield, Keith; Meyerholz, David K.; Price, Shari; Rebelatto, Marlon C. 分享 收藏
Combining mass spectrometry with quantitative continuous scoring to unlock the full quantitative potential of immunohistochemistry 结合质谱技术与定量连续评分，以释放免疫组织化学的完整定量潜力 Hidalgo-Sastre, A.; Zaucha, J.; Damond, N.; Tan, T. H.; Meier, A.; Schick, M.; Korade, M.; Kunihiro, A.; Chambers, A.; Durham, N.; Barrett, J. C.; Schmidt, G.; Sade, H.; Kim, Y. J.; Gustavson, M.; Reis-Filho, J. S.; Rebelatto, M. C.; Giraldo, N. 分享 收藏
ASCT2-Targeting Antibody-Drug Conjugate MEDI7247 in Adult Patients with Relapsed/Refractory Hematological Malignancies: A First-in-Human, Phase 1 Study Maris, Michael; Salles, Gilles; Kim, Won Seog; Kim, Tae Min; Lyons, Roger M.; Arellano, Martha; Karmali, Reem; Schiller, Gary; Cull, Elizabeth; Abboud, Camille N.; Batlevi, Connie; Kagiampakis, Ioannis; Rebelatto, Marlon C.; Lee, Young; Kirby, Lyndon C.; Wang, Fujun; Bothos, John; Townsley, Danielle M.; Fathi, Amir T.; Ribrag, Vincent 分享 收藏
Targeted proteomics and next-generation sequencing (NGS) for biomarker discovery in metastatic colorectal cancer (mCRC) Kelly, William J.; Nuttall, Barrett; Rebelatto, Marlon; Schick, Marcus; Meier, Armin; Sweet, Steve; Kim, Beom-Jun; Chain, David; Kim, Yeoun Jin; Lai, Zhongwu; Wang, Ying; Creasy, Todd H.; Gurrapu, Ramya; Gulati, Sakshi; Barkell, Alice; Dougherty, Brian; Carroll, Danielle; Cecchi, Fabiola 分享 收藏
Dynamics of TROP2 expression in triple-negative breast cancer Garrido-Castro, A. C.; Zanudo, J. Gomez Tejeda; Navarro, J.; Barkell, A. M.; Frangieh, A.; Mohammed-Abreu, A.; Hughes, M. E.; Kurt, B. Binboga; Hill, R. J.; King, T. A.; Mittendorf, E. A.; Rebelatto, M. C.; Carroll, D.; Lin, N. U.; Tolaney, S. M.; De Bruin, E. C. 分享 收藏
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Chronic pharmacological antagonism of the GM-CSF receptor in mice does not replicate the pulmonary alveolar proteinosis phenotype but does alter lung surfactant turnover Corkill, Dominic J.; Hunt, Alan N.; Hinrichs, Mary Jane; White, Nicholas; Rebelatto, Marlon; Roskos, Lorin; Nys, Josquin; Scott, Alison; Robinson, Matthew J.; Ryan, Patricia; Postle, Anthony D.; Sleeman, Matthew A. 分享 收藏
Domain Adaptation-Based Deep Learning for Automated Tumor Cell (TC) Scoring and Survival Analysis on PD-L1 Stained Tissue Images 基于域自适应的深度学习，用于PD-L1染色组织图像的自动肿瘤细胞 (TC) 评分和生存分析 Kapil, Ansh; Meier, Armin; Steele, Keith; Rebelatto, Marlon; Nekolla, Katharina; Haragan, Alexander; Silva, Abraham; Zuraw, Aleksandra; Barker, Craig; Scott, Marietta L.; Wiestler, Tobias; Lanzmich, Simon; Schmidt, Gunter; Brieu, Nicolas 分享 收藏
TUMORAL AND PERIPHERAL IMMUNOPHENOTYPE OF REFRACTORY VS RELAPSE TO PD-(L)1 BLOCKADE IN PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER Ascierto, Maria; Hellmann, Matthew; Standifer, Nathan; Wu, Song; Si, Han; Morehouse, Chris; Rebelatto, Marlon; Abdullah, Shaad; Raja, Rajiv; Soria, Jean-Charles; Germa, Caroline; Barrett, Carl 分享 收藏
PD-L1 prevalence in advanced urothelial carcinoma by demographic and clinical characteristics Powles, T. B.; van der Heijden, M. S.; Balar, A. V.; O'Donnell, P.; Massard, C.; Walker, J.; Gupta, A.; Angra, N.; Cairns, J.; Turriziani, B.; Rebelatto, M. C.; Scott, M.; Wildsmith, S. 分享 收藏
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The Society for Immunotherapy of Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation Taube, Janis M.; Akturk, Guray; Angelo, Michael; Engle, Elizabeth L.; Gnjatic, Sacha; Greenbaum, Shirley; Greenwald, Noah F.; Hedvat, Cyrus, V; Hollmann, Travis J.; Juco, Jonathan; Parra, Edwin R.; Rebelatto, Marlon C.; Rimm, David L.; Rodriguez-Canales, Jaime; Schalper, Kurt A.; Stack, Edward C.; Ferreira, Claudia S.; Korski, Konstanty; Lako, Ana; Rodig, Scott J.; Schenck, Emanuel; Steele, Keith E.; Surace, Michael J.; Tetzlaff, Michael T.; von Loga, Katharina; Wistuba, Ignacio I.; Bifulco, Carlo B. 分享 收藏
Comparison of continuous measures across diagnostic PD-L1 assays in non-small cell lung cancer using automated image analysis Widmaier, Moritz; Wiestler, Tobias; Walker, Jill; Barker, Craig; Scott, Marietta L.; Sekhavati, Farzad; Budco, Alexei; Schneider, Katrin; Segerer, Felix J.; Steele, Keith; Rebelatto, Marlon C. 分享 收藏
Safety and Efficacy of Durvalumab and Tremelimumab Alone or in Combination in Patients with Advanced Gastric and Gastroesophageal Junction Adenocarcinoma Kelly, Ronan J.; Lee, Jeeyun; Bang, Yung-Jue; Almhanna, Khaldoun; Blum-Murphy, Mariela; Catenacci, Daniel V. T.; Hyun Cheol Chung; Wainberg, Zev A.; Gibson, Michael K.; Lee, Keun-Wook; Bendell, Johanna C.; Denlinger, Crystal S.; Chee, Cheng Ean; Omori, Takeshi; Leidner, Rom; Lenz, Heinz-Josef; Chao, Yee; Rebelatto, Marlon C.; Brohawn, Philip Z.; He, Peng; McDevitt, Jennifer; Sheth, Siddharth; Englert, Judson M.; Ku, Geoffrey Y. 分享 收藏
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Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy NSCLC活检的自动图像分析以预测对anti-PD-L1治疗的反应 Althammer, Sonja; Tan, Tze Heng; Spitzmuller, Andreas; Rognoni, Lorenz; Wiestler, Tobias; Herz, Thomas; Widmaier, Moritz; Rebelatto, Marlon C.; Kaplon, Helene; Damotte, Diane; Alifano, Marco; Hammond, Scott A.; Dieu-Nosjean, Marie-Caroline; Ranade, Koustubh; Schmidt, Guenter; Higgs, Brandon W.; Steele, Keith E. 分享 收藏
Safety and efficacy of durvalumab in patients with head and neck squamous cell carcinoma: results from a phase I/II expansion cohort Segal, Neil H.; Ou, Sai-Hong, I; Balmanoukian, Ani; Fury, Matthew G.; Massarelli, Etiuinia; Brahmer, Julie R.; Weiss, Jared; Schoffski, Patrick; Antonia, Scott J.; Massard, Christophe; Zandberg, Dan P.; Khleif, Samir N.; Xiao, Feng; Rebelatto, Marlon C.; Steele, Keith E.; Robbins, Paul B.; Angra, Natasha; Song, Xuyang; Abdullah, Shaad; Butler, Marcus 分享 收藏
SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked Maytansinoid and Pyrrolobenzodiazepine Warheads Kinneer, Krista; Meekin, John; Tiberghien, Arnaud C.; Tai, Yu-Tzu; Phipps, Sandrina; Kiefer, Christine Mione; Rebelatto, Marlon C.; Dimasi, Nazzareno; Moriarty, Alyssa; Papadopoulos, Kyriakos P.; Sridhar, Sriram; Gregson, Stephen J.; Wick, Michael J.; Masterson, Luke; Anderson, Kenneth C.; Herbst, Ronald; Howard, Philip W.; Tice, David A. 分享 收藏
Analytical Validation and Clinical Utility of an Immunohistochemical Programmed Death Ligand-1 Diagnostic Assay and Combined Tumor and Immune Cell Scoring Algorithm for Durvalumab in Urothelial Carcinoma Zajac, Magdalena; Boothman, Anne-Marie; Ben, Yong; Gupta, Ashok; Jin, Xiaoping; Mistry, Amita; Sabalos, Constantine; Nielsen, Alma; Manriquez, Guadalupe; Barker, Craig; Antal, Joyce; Wang, Peiyi; Patil, Pallavi; Schechter, Nicole; Rebelatto, Marlon C.; Walker, Jill 分享 收藏
PD-L1 expression in patients screened for phase 2 head and neck squamous cell carcinoma clinical studies (HAWK and CONDOR) Wildsmith, Sophie; Scott, Marietta; Midha, Anita; Barker, Craig; Whiteley, Jessica; Ratcliffe, Marianne; Rebelatto, Marlon; Walker, Jill; Zandberg, Dan; Siu, Lillian L. 分享 收藏
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