未登录 Investigating chromosomal instability in long-term survivors with glioblastoma and grade 4 astrocytoma Spoor, Jochem K. H.; den Braber, May; Dirven, Clemens M. F.; Pennycuick, Adam; Bartkova, Jirina; Bartek, Jiri; van Dis, Vera; van den Bosch, Thierry P. P.; Leenstra, Sieger; Venkatesan, Subramanian 分享 收藏
Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET Kanellis, Dimitris C.; Zisi, Asimina; Skrott, Zdenek; Lemmens, Bennie; Espinoza, Jaime A.; Kosar, Martin; Bjorkman, Andrea; Li, Xuexin; Arampatzis, Stefanos; Bartkova, Jirina; Andujar-Sanchez, Miguel; Fernandez-Capetillo, Oscar; Mistrik, Martin; Lindstrom, Mikael S.; Bartek, Jiri 分享 收藏
Markers associated with genomic instability, immunogenicity and immune therapy responsiveness in Metaplastic carcinoma of the breast: Expression of γH2AX, pRPA2, P53, PD-L1 and tumor infiltrating lymphocytes in 76 cases Voutilainen, S.; Heikkila, P.; Bartkova, J.; Nevanlinna, H.; Blomqvist, C.; Bartek, J.; Mattson, J. 分享 收藏
Human cytomegalovirus hijacks host stress response fueling replication stress and genome instability Merchut-Maya, Joanna Maria; Bartek, Jiri, Jr.; Bartkova, Jirina; Galanos, Panagiotis; Pantalone, Mattia Russel; Lee, MyungHee; Cui, Huanhuan L.; Shilling, Patrick J.; Brochner, Christian Beltoft; Broholm, Helle; Maya-Mendoza, Apolinar; Soderberg-Naucler, Cecilia; Bartek, Jiri 分享 收藏
Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps 通过暴露ssDNA缺口，核DNA连接酶III的丧失可恢复BRCA1/53BP1双缺陷细胞中的PARP抑制剂抗性 Dias, Mariana Paes; Tripathi, Vivek; van der Heijden, Ingrid; Cong, Ke; Manolika, Eleni-Maria; Bhin, Jinhyuk; Gogola, Ewa; Galanos, Panagiotis; Annunziato, Stefano; Lieftink, Cor; Andujar-Sanchez, Miguel; Chakrabarty, Sanjiban; Smith, Graeme C. M.; van de Ven, Marieke; Beijersbergen, Roderick L.; Bartkova, Jirina; Rottenberg, Sven; Cantor, Sharon; Bartek, Jiri; Chaudhuri, Arnab Ray; Jonkers, Jos 分享 收藏
The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output Kanellis, Dimitris C.; Espinoza, Jaime A.; Zisi, Asimina; Sakkas, Elpidoforos; Bartkova, Jirina; Katsori, Anna-Maria; Bostrom, Johan; Dyrskjot, Lars; Broholm, Helle; Altun, Mikael; Elsasser, Simon J.; Lindstrom, Mikael S.; Bartek, Jiri 分享 收藏
The human nucleoporin Tpr protects cells from RNA-mediated replication stress Kosar, Martin; Giannattasio, Michele; Piccini, Daniele; Maya-Mendoza, Apolinar; Garcia-Benitez, Francisco; Bartkova, Jirina; Barroso, Sonia I.; Gaillard, Helene; Martini, Emanuele; Restuccia, Umberto; Ramirez-Otero, Miguel Angel; Garre, Massimiliano; Verga, Eleonora; Andujar-Sanchez, Miguel; Maynard, Scott; Hodny, Zdenek; Costanzo, Vincenzo; Kumar, Amit; Bachi, Angela; Aguilera, Andres; Bartek, Jiri; Foiani, Marco 分享 收藏
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution APOBEC3的诱导加剧了早期乳腺癌和肺癌演变中的DNA复制应激和染色体不稳定性 Venkatesan, Subramanian; Angelova, Mihaela; Puttick, Clare; Zhai, Haoran; Caswell, Deborah R.; Lu, Wei-Ting; Dietzen, Michelle; Galanos, Panagiotis; Evangelou, Konstantinos; Bellelli, Roberto; Lim, Emilia L.; Watkins, Thomas B. K.; Rowan, Andrew; Teixeira, Vitor H.; Zhao, Yue; Chen, Haiquan; Ngo, Bryan; Zalmas, Lykourgos-Panagiotis; Al Bakir, Maise; Hobor, Sebastijan; Gronroos, Eva; Pennycuick, Adam; Nigro, Ersilia; Campbell, Brittany B.; Brown, William L.; Akarca, Ayse U.; Marafioti, Teresa; Wu, Mary Y.; Howell, Michael; Boulton, Simon J.; Bertoli, Cosetta; Fenton, Tim R.; de Bruin, Robertus A. M.; Maya-Mendoza, Apolinar; Santoni-Rugiu, Eric; Hynds, Robert E.; Gorgoulis, Vassilis G.; Jamal-Hanjani, Mariam; McGranahan, Nicholas; Harris, Reuben S.; Janes, Sam M.; Bartkova, Jirina; Bakhoum, Samuel F.; Bartek, Jiri; Kanu, Nnennaya; Swanton, Charles 分享 收藏
Cancer cell stemness, responses to experimental genotoxic treatments, cytomegalovirus protein expression and DNA replication stress in pediatric medulloblastomas Bartek, Jiri, Jr.; Merchut-Maya, Joanna M.; Maya-Mendoza, Apolinar; Fornara, Olesja; Rahbar, Afsar; Brochner, Christian Beltoft; Sehested, Astrid; Soderberg-Naucler, Cecilia; Bartek, Jiri; Bartkova, Jirina 分享 收藏
Autophagy role(s) in response to oncogenes and DNA replication stress Vanzo, Riccardo; Bartkova, Jirina; Merchut-Maya, Joanna Maria; Hall, Arnaldur; Bouchal, Jan; Dyrskjot, Lars; Frankel, Lisa B.; Gorgoulis, Vassilis; Maya-Mendoza, Apolinar; Jaattela, Marja; Bartek, Jiri 分享 收藏
DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy Bennetzen, Martin V.; Kosar, Martin; Bunkenborg, Jakob; Payne, Mark Ronald; Bartkova, Jirina; Lindstrom, Mikael S.; Lukas, Jiri; Andersen, Jens S.; Bartek, Jiri; Larsen, Dorthe Helena 分享 收藏
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4 酒精滥用药物双硫仑通过p97分离酶适配器NPL4靶向癌症 Skrott, Zdenek; Mistrik, Martin; Andersen, Klaus Kaae; Friis, Soren; Majera, Dusana; Gursky, Jan; Ozdian, Tomas; Bartkova, Jirina; Turi, Zsofia; Moudry, Pavel; Kraus, Marianne; Michalova, Martina; Vaclavkova, Jana; Dzubak, Petr; Vrobel, Ivo; Pouckova, Pavla; Sedlacek, Jindrich; Miklovicova, Andrea; Kutt, Anne; Li, Jing; Mattova, Jana; Driessen, Christoph; Dou, Q. Ping; Olsen, Jorgen; Hajduch, Marian; Cvek, Boris; Deshaies, Raymond J.; Bartek, Jiri 分享 收藏
Replication stress, DNA damage signalling, and cytomegalovirus infection in human medulloblastomas Bartek, Jiri, Jr.; Fornara, Olesja; Merchut-Maya, Joanna Maria; Maya-Mendoza, Apolinar; Rahbar, Afshar; Stragliotto, Giuseppe; Broholm, Helle; Svensson, Mikael; Sehested, Astrid; Naucler, Cecilia Soderberg; Bartek, Jiri; Bartkova, Jirina 分享 收藏
分享 收藏
Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress 过表达RNF168的肿瘤显示出改变的DNA修复和对基因毒性治疗的反应，基因组不稳定性和对蛋白毒性应激的抗性 Chroma, K.; Mistrik, M.; Moudry, P.; Gursky, J.; Liptay, M.; Strauss, R.; Skrott, Z.; Vrtel, R.; Bartkova, J.; Kramara, J.; Bartek, J. 分享 收藏
FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome Kiiski, Johanna I.; Fagerholm, Rainer; Tervasmaki, Anna; Pelttari, Liisa M.; Khan, Sofia; Jamshidi, Maral; Mantere, Tuomo; Pylkas, Katri; Bartek, Jiri; Bartkova, Jirina; Mannermaa, Arto; Tengstrom, Maria; Kosma, Veli-Matti; Winqvist, Robert; Kallioniemi, Anne; Aittomaki, Kristiina; Blomqvist, Carl; Nevanlinna, Heli 分享 收藏
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer Kanu, Nnennaya; Cerone, Maria Antonietta; Goh, Gerald; Zalmas, Lykourgos-Panagiotis; Bartkova, Jirina; Dietzen, Michelle; McGranahan, Nicholas; Rogers, Rebecca; Law, Emily K.; Gromova, Irina; Kschischo, Maik; Walton, Michael I.; Rossanese, Olivia W.; Bartek, Jiri; Harris, Reuben S.; Venkatesan, Subramanian; Swanton, Charles 分享 收藏
DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer Kurfurstova, Daniela; Bartkova, Jirina; Vrtel, Radek; Mickova, Alena; Burclova, Alena; Majera, Dusana; Mistrik, Martin; Kral, Milan; Santer, Frederic R.; Bouchal, Jan; Bartek, Jiri 分享 收藏
TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity Moudry, Pavel; Watanabe, Kenji; Wolanin, Kamila M.; Bartkova, Jirina; Wassing, Isabel E.; Watanabe, Sugiko; Strauss, Robert; Pedersen, Rune Troelsgaard; Oestergaard, Vibe H.; Lisby, Michael; Andujar-Sanchez, Miguel; Maya-Mendoza, Apolinar; Esashi, Fumiko; Lukas, Jiri; Bartek, Jiri 分享 收藏
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair Kanu, N.; Groenroos, E.; Martinez, P.; Burrell, R. A.; Goh, X. Yi; Bartkova, J.; Maya-Mendoza, A.; Mistrik, M.; Rowan, A. J.; Patel, H.; Rabinowitz, A.; East, P.; Wilson, G.; Santos, C. R.; McGranahan, N.; Gulati, S.; Gerlinger, M.; Birkbak, N. J.; Joshi, T.; Alexandrov, L. B.; Stratton, M. R.; Powles, T.; Matthews, N.; Bates, P. A.; Stewart, A.; Szallasi, Z.; Larkin, J.; Bartek, J.; Swanton, C. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
